Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sh3glb2 | Mouse | (+)-schisandrin B | multiple interactions | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SH3GLB2 mRNA] | CTD | PMID:31150632 | Sh3glb2 | Mouse | 1,3-dinitrobenzene | increases expression | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | 3-dinitrobenzene results in increased expression of SH3GLB2 mRNA | CTD | PMID:21983209 | Sh3glb2 | Mouse | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SH3GLB2 mRNA | CTD | PMID:17942748 | Sh3glb2 | Mouse | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SH3GLB2 mRNA | CTD | PMID:17942748 | Sh3glb2 | Mouse | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of SH3GLB2 mRNA | CTD | PMID:17555576 | Sh3glb2 | Mouse | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Metribolone results in increased expression of SH3GLB2 mRNA | CTD | PMID:17010196 | Sh3glb2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SH3GLB2 mRNA | CTD | PMID:17942748 | Sh3glb2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SH3GLB2 mRNA | CTD | PMID:32109520 and PMID:34747641 | Sh3glb2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SH3GLB2 mRNA | CTD | PMID:21570461 | Sh3glb2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SH3GLB2 mRNA | CTD | PMID:17942748 | Sh3glb2 | Mouse | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of SH3GLB2 protein | CTD | PMID:31675489 | Sh3glb2 | Mouse | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of SH3GLB2 mRNA | CTD | PMID:18648102 | Sh3glb2 | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SH3GLB2 mRNA | CTD | PMID:36041667 | Sh3glb2 | Mouse | acrylamide | decreases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of SH3GLB2 mRNA | CTD | PMID:32763439 | Sh3glb2 | Mouse | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of SH3GLB2 mRNA | CTD | PMID:19770486 | Sh3glb2 | Mouse | aristolochic acid A | decreases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SH3GLB2 mRNA and aristolochic acid I results in decreased expression of SH3GLB2 protein | CTD | PMID:33212167 | Sh3glb2 | Mouse | bisphenol A | decreases expression | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SH3GLB2 mRNA | CTD | PMID:25181051 | Sh3glb2 | Mouse | bisphenol A | multiple interactions | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SH3GLB2 mRNA | CTD | PMID:36041667 | Sh3glb2 | Mouse | bisphenol A | decreases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SH3GLB2 protein | CTD | PMID:31675489 | Sh3glb2 | Mouse | bisphenol F | multiple interactions | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SH3GLB2 mRNA | CTD | PMID:36041667 | Sh3glb2 | Mouse | bortezomib | decreases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of SH3GLB2 mRNA | CTD | PMID:20977926 | Sh3glb2 | Mouse | caffeine | decreases phosphorylation | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of SH3GLB2 protein | CTD | PMID:35688186 | Sh3glb2 | Mouse | chlordecone | increases expression | EXP | | 6480464 | Chlordecone results in increased expression of SH3GLB2 mRNA | CTD | PMID:33711761 | Sh3glb2 | Mouse | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of SH3GLB2 mRNA | CTD | PMID:32715474 | Sh3glb2 | Mouse | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of SH3GLB2 mRNA | CTD | PMID:37019170 | Sh3glb2 | Mouse | cisplatin | increases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of SH3GLB2 mRNA | CTD | PMID:27392435 | Sh3glb2 | Mouse | cisplatin | multiple interactions | ISO | SH3GLB2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of SH3GLB2 mRNA | CTD | PMID:27392435 | Sh3glb2 | Mouse | cobalt dichloride | decreases expression | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of SH3GLB2 mRNA | CTD | PMID:24386269 | Sh3glb2 | Mouse | cobalt dichloride | decreases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of SH3GLB2 mRNA | CTD | PMID:19376846 | Sh3glb2 | Mouse | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of SH3GLB2 mRNA | CTD | PMID:19770486 | Sh3glb2 | Mouse | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of SH3GLB2 mRNA | CTD | PMID:17361019 | Sh3glb2 | Mouse | dorsomorphin | multiple interactions | ISO | SH3GLB2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SH3GLB2 mRNA | CTD | PMID:27188386 | Sh3glb2 | Mouse | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of SH3GLB2 mRNA | CTD | PMID:30319688 | Sh3glb2 | Mouse | folic acid | increases expression | EXP | | 6480464 | Folic Acid results in increased expression of SH3GLB2 mRNA | CTD | PMID:25629700 | Sh3glb2 | Mouse | formaldehyde | decreases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of SH3GLB2 mRNA | CTD | PMID:27905399 | Sh3glb2 | Mouse | furan | increases methylation | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | furan results in increased methylation of SH3GLB2 gene | CTD | PMID:22079235 | Sh3glb2 | Mouse | gentamycin | decreases expression | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of SH3GLB2 mRNA | CTD | PMID:33387578 | Sh3glb2 | Mouse | hydrogen cyanide | decreases expression | EXP | | 6480464 | Hydrogen Cyanide results in decreased expression of SH3GLB2 mRNA | CTD | PMID:33914522 | Sh3glb2 | Mouse | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SH3GLB2 mRNA | CTD | PMID:36331819 | Sh3glb2 | Mouse | ivermectin | decreases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SH3GLB2 protein | CTD | PMID:32959892 | Sh3glb2 | Mouse | mercury atom | increases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Mercury results in increased expression of SH3GLB2 mRNA | CTD | PMID:16823088 | Sh3glb2 | Mouse | mercury(0) | increases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Mercury results in increased expression of SH3GLB2 mRNA | CTD | PMID:16823088 | Sh3glb2 | Mouse | methotrexate | affects response to substance | ISO | SH3GLB2 (Homo sapiens) | 6480464 | SH3GLB2 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | Sh3glb2 | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SH3GLB2 mRNA | CTD | PMID:17562736 | Sh3glb2 | Mouse | paracetamol | increases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SH3GLB2 mRNA | CTD | PMID:22230336 | Sh3glb2 | Mouse | paraquat | decreases expression | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | Paraquat results in decreased expression of SH3GLB2 mRNA | CTD | PMID:32680482 | Sh3glb2 | Mouse | pentachlorophenol | decreases expression | EXP | | 6480464 | Pentachlorophenol results in decreased expression of SH3GLB2 mRNA | CTD | PMID:23892564 | Sh3glb2 | Mouse | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SH3GLB2 mRNA | CTD | PMID:36331819 | Sh3glb2 | Mouse | potassium cyanide | increases expression | EXP | | 6480464 | Potassium Cyanide results in increased expression of SH3GLB2 mRNA | CTD | PMID:33914522 | Sh3glb2 | Mouse | potassium dichromate | increases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of SH3GLB2 protein | CTD | PMID:23718831 | Sh3glb2 | Mouse | SB 431542 | multiple interactions | ISO | SH3GLB2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SH3GLB2 mRNA | CTD | PMID:27188386 | Sh3glb2 | Mouse | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of SH3GLB2 protein | CTD | PMID:28918527 | Sh3glb2 | Mouse | sunitinib | increases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SH3GLB2 mRNA | CTD | PMID:31533062 | Sh3glb2 | Mouse | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of SH3GLB2 mRNA | CTD | PMID:17555576 | Sh3glb2 | Mouse | tetrachloromethane | multiple interactions | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SH3GLB2 mRNA] | CTD | PMID:31150632 | Sh3glb2 | Mouse | tetrachloromethane | decreases expression | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of SH3GLB2 mRNA | CTD | PMID:31150632 | Sh3glb2 | Mouse | thioacetamide | decreases expression | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of SH3GLB2 mRNA | CTD | PMID:34492290 | Sh3glb2 | Mouse | trichloroethene | increases methylation | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased methylation of SH3GLB2 gene | CTD | PMID:27618143 | Sh3glb2 | Mouse | triphenyl phosphate | affects expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SH3GLB2 mRNA | CTD | PMID:37042841 | Sh3glb2 | Mouse | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of SH3GLB2 mRNA | CTD | PMID:17292431 | Sh3glb2 | Mouse | valproic acid | increases expression | ISO | SH3GLB2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SH3GLB2 mRNA | CTD | PMID:26272509 | Sh3glb2 | Mouse | valproic acid | multiple interactions | ISO | SH3GLB2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SH3GLB2 mRNA | CTD | PMID:27188386 | Sh3glb2 | Mouse | valproic acid | affects splicing | ISO | Sh3glb2 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of SH3GLB2 mRNA | CTD | PMID:29427782 | |