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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chromatographic reagent
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Accession:CHEBI:59745 term browser browse the term
Definition:A reagent used to improve selectivity in chromatographic analyses or separations, e.g. by formation of a derivative or by modification of the mobile phase.
Synonyms:related_synonym: derivatising reagents;   derivatizing reagent;   derivatizing reagents


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1-fluoro-2,4-dinitrobenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin increases expression ISO Dinitrofluorobenzene results in increased expression of ADM mRNA CTD PMID:23999411 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Akirin2 akirin 2 increases expression ISO Dinitrofluorobenzene results in increased expression of AKIRIN2 mRNA CTD PMID:23999411 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Dinitrofluorobenzene results in increased phosphorylation of AKT1 protein CTD PMID:23445166 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Dinitrofluorobenzene results in increased expression of AQP3 mRNA CTD PMID:21362464 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Arg2 arginase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of ARG2 mRNA CTD PMID:23999411 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Dinitrofluorobenzene results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO Dinitrofluorobenzene results in increased expression of BABAM2 mRNA CTD PMID:23999411 NCBI chr 6:24,369,021...24,788,416
Ensembl chr 6:24,369,022...24,833,951 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased expression of and results in increased activity of CASP1 protein]; Dinitrofluorobenzene results in increased expression of and results in increased activity of CASP1 protein CTD PMID:30183461 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 multiple interactions
increases expression		 ISO cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased expression of CCL17 mRNA] CTD PMID:30183461 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO [CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene
Dinitrofluorobenzene results in increased expression of CCL2 mRNA		 CTD PMID:15719370 PMID:21362464 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL3 mRNA CTD PMID:15719370 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL4 mRNA
Dinitrofluorobenzene results in increased expression of CCL4 protein		 CTD PMID:15719370 PMID:18353026 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL5 mRNA; Dinitrofluorobenzene results in increased expression of CCL5 protein CTD PMID:15719370 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccne2 cyclin E2 increases expression ISO Dinitrofluorobenzene results in increased expression of CCNE2 mRNA CTD PMID:23999411 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression
multiple interactions		 ISO Dinitrofluorobenzene results in increased expression of CCR2 mRNA
[CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene		 CTD PMID:21362464 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 multiple interactions
increases expression		 ISO cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased expression of CCR3 mRNA] CTD PMID:30183461 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 decreases expression ISO Dinitrofluorobenzene results in decreased expression of CCR6 protein CTD PMID:15924226 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Cd83 CD83 molecule increases expression ISO Dinitrofluorobenzene results in increased expression of CD83 protein CTD PMID:21362464 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Cd86 CD86 molecule increases expression ISO Dinitrofluorobenzene results in increased expression of CD86 protein CTD PMID:21362464 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO Dinitrofluorobenzene affects the expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crem cAMP responsive element modulator increases expression ISO Dinitrofluorobenzene results in increased expression of CREM mRNA CTD PMID:21362464 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
decreases expression		 ISO Dinitrofluorobenzene results in increased expression of CXCL10 mRNA; Dinitrofluorobenzene results in increased expression of CXCL10 protein
Dinitrofluorobenzene results in decreased expression of CXCL10 mRNA		 CTD PMID:15719370 PMID:23445166 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Dinitrofluorobenzene results in increased expression of CXCL1 mRNA CTD PMID:15719370 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Dinitrofluorobenzene results in decreased expression of CXCR4 protein CTD PMID:15924226 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cytip cytohesin 1 interacting protein increases expression ISO Dinitrofluorobenzene results in increased expression of CYTIP mRNA CTD PMID:21362464 NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of DHRS2 mRNA CTD PMID:23999411 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Dinitrofluorobenzene results in increased expression of DNAJB4 mRNA CTD PMID:23999411 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO Dinitrofluorobenzene results in increased expression of EIF1 mRNA CTD PMID:23999411 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327 		JBrowse link
G Epc1 enhancer of polycomb homolog 1 increases expression ISO Dinitrofluorobenzene results in increased expression of EPC1 mRNA CTD PMID:23999411 NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Dinitrofluorobenzene results in increased expression of FOSB mRNA CTD PMID:23999411 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Dinitrofluorobenzene results in increased expression of GCLC mRNA CTD PMID:23999411 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Dinitrofluorobenzene results in increased expression of GCLM mRNA CTD PMID:23999411 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO Dinitrofluorobenzene results in increased expression of H2AX mRNA CTD PMID:23999411 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of HMOX1 mRNA CTD PMID:23445166 PMID:25091725 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Dinitrofluorobenzene results in increased expression of HSPA1A mRNA CTD PMID:23999411 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO Dinitrofluorobenzene results in increased expression of HSPA6 mRNA CTD PMID:23999411 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Dinitrofluorobenzene results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression		 ISO doramapimod inhibits the reaction [Dinitrofluorobenzene results in increased expression of ICAM1 protein] CTD PMID:19427879 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma increases expression
multiple interactions		 ISO Dinitrofluorobenzene results in increased expression of IFNG mRNA; Dinitrofluorobenzene results in increased expression of IFNG protein
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IFNG mRNA]		 CTD PMID:11243917 PMID:11244134 PMID:23499868 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il10 interleukin 10 increases expression ISO Dinitrofluorobenzene results in increased expression of IL10 mRNA CTD PMID:11243917 PMID:23499868 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B increases expression ISO Dinitrofluorobenzene results in increased expression of IL12B mRNA CTD PMID:11708898 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha increases response to substance ISO IL15RA protein results in increased susceptibility to Dinitrofluorobenzene CTD PMID:15719370 NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278 		JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions		 ISO Dinitrofluorobenzene results in increased expression of IL17A mRNA
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IL17A mRNA]		 CTD PMID:23499868 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17f interleukin 17F increases expression ISO Dinitrofluorobenzene results in increased expression of IL17F mRNA CTD PMID:23445166 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482 		JBrowse link
G Il1a interleukin 1 alpha increases expression
affects secretion		 ISO Dinitrofluorobenzene results in increased expression of IL1A mRNA; Dinitrofluorobenzene results in increased expression of IL1A protein
Dinitrofluorobenzene affects the secretion of IL1A protein		 CTD PMID:8006454 PMID:12781210 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il2 interleukin 2 increases expression ISO Dinitrofluorobenzene results in increased expression of IL2 mRNA; Dinitrofluorobenzene results in increased expression of IL2 protein CTD PMID:11244134 PMID:22381623 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions
increases secretion		 ISO Dinitrofluorobenzene results in increased expression of IL4 mRNA
cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased secretion of IL4 protein]		 CTD PMID:23499868 PMID:30183461 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Dinitrofluorobenzene results in increased expression of IL4RA protein CTD PMID:22381623 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions		 ISO Dinitrofluorobenzene results in increased secretion of IL6 protein
cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased secretion of IL6 protein]		 CTD PMID:30183461 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Dinitrofluorobenzene results in increased expression of MAFF mRNA CTD PMID:23999411 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions		 ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein]		 CTD PMID:27129696 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK14 protein CTD PMID:19427879 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein]		 CTD PMID:27129696 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]		 CTD PMID:27129696 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions		 ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein]		 CTD PMID:27129696 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO Dinitrofluorobenzene results in increased expression of MIF mRNA CTD PMID:11244134 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Dinitrofluorobenzene results in increased expression of MXD1 mRNA CTD PMID:21362464 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Dinitrofluorobenzene results in increased expression of NAMPT mRNA CTD PMID:21362464 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NFE2L2 protein CTD PMID:19427879 PMID:26022718 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO Dinitrofluorobenzene results in decreased expression of NFKB1 mRNA CTD PMID:20385217 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of NQO1 mRNA CTD PMID:23445166 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NR2F2 mRNA CTD PMID:23999411 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NTRK2 mRNA CTD PMID:23999411 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Peg10 paternally expressed 10 increases expression ISO Dinitrofluorobenzene results in increased expression of PEG10 mRNA CTD PMID:23999411 NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Dinitrofluorobenzene results in increased expression of PMAIP1 mRNA CTD PMID:23999411 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 ISO Dinitrofluorobenzene results in increased expression of PTGS2 mRNA; Dinitrofluorobenzene results in increased expression of PTGS2 protein
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which affects the susceptibility to Dinitrofluorobenzene		 CTD PMID:21362464 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Dinitrofluorobenzene results in increased expression of PTX3 mRNA CTD PMID:23999411 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Dinitrofluorobenzene results in increased expression of RGS16 mRNA CTD PMID:23999411 NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO Dinitrofluorobenzene results in increased expression of SLC2A3 mRNA CTD PMID:21362464 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases response to substance		 ISO Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene] CTD PMID:14555839 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 increases expression ISO Dinitrofluorobenzene results in increased expression of TAF7 mRNA CTD PMID:23999411 NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TGFB1 mRNA CTD PMID:11244134 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 increases expression ISO Dinitrofluorobenzene results in increased expression of TICAM2 mRNA CTD PMID:23999411 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tnf tumor necrosis factor affects expression
increases expression
multiple interactions
increases secretion		 ISO Dinitrofluorobenzene affects the expression of TNF mRNA
Dinitrofluorobenzene results in increased expression of TNF mRNA
cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased secretion of TNF protein]; oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of TNF mRNA]		 CTD PMID:20385217 PMID:23499868 PMID:30183461 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO Dinitrofluorobenzene results in increased expression of TNFRSF10A mRNA CTD PMID:23999411 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TRIB1 mRNA CTD PMID:23999411 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trim27 tripartite motif-containing 27 increases expression ISO Dinitrofluorobenzene results in increased expression of TRIM27 mRNA CTD PMID:23999411 NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643 		JBrowse link
G Tslp thymic stromal lymphopoietin increases secretion
multiple interactions
increases expression		 ISO Dinitrofluorobenzene results in increased secretion of TSLP protein
cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased expression of TSLP mRNA]; cordycepin inhibits the reaction [Dinitrofluorobenzene results in increased secretion of TSLP protein]		 CTD PMID:30183461 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TXNRD1 mRNA CTD PMID:23445166 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 increases expression ISO Dinitrofluorobenzene results in increased expression of XCL1 mRNA CTD PMID:15719370 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
G Zfp870 zinc finger protein 870 increases expression ISO Dinitrofluorobenzene results in increased expression of ZNF670 mRNA CTD PMID:23999411 NCBI chr 7:11,990,146...12,003,813
Ensembl chr 7:11,990,148...12,003,813 		JBrowse link
G Zxdb zinc finger, X-linked, duplicated B increases expression ISO Dinitrofluorobenzene results in increased expression of ZXDB mRNA CTD PMID:23999411 NCBI chr  X:59,700,765...59,706,737
Ensembl chr  X:59,701,178...59,703,871
Ensembl chr  X:59,701,178...59,703,871 		JBrowse link
perfluorobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO perfluorobutyric acid results in decreased expression of A2M mRNA CTD PMID:36251517 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO perfluorobutyric acid results in increased expression of ABCA1 mRNA CTD PMID:35337807 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO perfluorobutyric acid results in increased expression of ABCB4 mRNA CTD PMID:34474067 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO perfluorobutyric acid results in increased expression of ABCC2 mRNA CTD PMID:34474067 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO perfluorobutyric acid results in increased expression of ABCC3 mRNA CTD PMID:34474067 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression EXP
ISO		 perfluorobutyric acid analog results in increased expression of ACACA mRNA
perfluorobutyric acid results in increased expression of ACACA mRNA		 CTD PMID:21878386 PMID:36251517 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression EXP perfluorobutyric acid results in increased expression of ACOT1 mRNA CTD PMID:19407336 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP
ISO		 perfluorobutyric acid analog results in increased expression of ACOX1 mRNA; perfluorobutyric acid results in increased expression of ACOX1 mRNA CTD PMID:19359353 PMID:19407336 PMID:21878386 PMID:34474067 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Actb actin, beta decreases expression ISO perfluorobutyric acid results in decreased expression of ACTB mRNA CTD PMID:23567314 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Alb albumin affects binding EXP
ISO		 perfluorobutyric acid binds to ALB protein CTD PMID:38518100 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression ISO perfluorobutyric acid results in decreased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO perfluorobutyric acid results in increased expression of APEX1 mRNA CTD PMID:34474067 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apoa1 apolipoprotein A1 decreases expression EXP perfluorobutyric acid analog results in decreased expression of APOA1 mRNA CTD PMID:21878386 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP perfluorobutyric acid affects the expression of APOA4 mRNA CTD PMID:22071372 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apob apolipoprotein B decreases expression ISO perfluorobutyric acid results in decreased expression of APOB mRNA CTD PMID:36251517 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Ar androgen receptor multiple interactions ISO perfluorobutyric acid promotes the reaction [Dihydrotestosterone results in increased activity of AR protein] CTD PMID:29601859 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO perfluorobutyric acid results in increased expression of ATF4 mRNA CTD PMID:36251517 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO perfluorobutyric acid results in increased expression of ATF6 mRNA CTD PMID:36251517 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atg3 autophagy related 3 increases expression ISO perfluorobutyric acid results in increased expression of ATG3 mRNA CTD PMID:37806615 NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO perfluorobutyric acid results in increased expression of BTG2 mRNA CTD PMID:34474067 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Ccng1 cyclin G1 increases expression ISO perfluorobutyric acid results in increased expression of CCNG1 mRNA CTD PMID:34474067 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd36 CD36 molecule increases expression ISO perfluorobutyric acid results in increased expression of CD36 mRNA CTD PMID:34474067 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO perfluorobutyric acid results in increased expression of CDKN1A mRNA CTD PMID:36251517 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chst9 carbohydrate sulfotransferase 9 decreases expression ISO perfluorobutyric acid results in decreased expression of CHST9 mRNA CTD PMID:36251517 NCBI chr18:6,576,391...6,851,078
Ensembl chr18:6,577,348...6,850,868 		JBrowse link
G Col17a1 collagen type XVII alpha 1 chain decreases expression ISO perfluorobutyric acid results in decreased expression of COL17A1 mRNA CTD PMID:36251517 NCBI chr 1:246,530,589...246,577,559
Ensembl chr 1:246,531,367...246,577,632 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression ISO perfluorobutyric acid results in increased expression of COL4A1 mRNA CTD PMID:34474067 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO perfluorobutyric acid results in decreased expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression ISO perfluorobutyric acid results in increased expression of CPT1B mRNA CTD PMID:23567314 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression ISO perfluorobutyric acid results in decreased expression of CXCL1 mRNA CTD PMID:36251517 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO perfluorobutyric acid results in decreased expression of CXCL1 mRNA CTD PMID:36251517 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression EXP
ISO		 perfluorobutyric acid analog results in decreased expression of CYP1A1 mRNA
perfluorobutyric acid results in decreased expression of CYP1A1 mRNA		 CTD PMID:21878386 PMID:23567314 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP2B2 mRNA CTD PMID:21878386 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP3A23-3A1 mRNA CTD PMID:21878386 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP4A1 mRNA; perfluorobutyric acid results in increased expression of CYP4A1 mRNA CTD PMID:19407336 PMID:21878386 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP7A1 mRNA CTD PMID:21878386 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP perfluorobutyric acid analog results in decreased expression of DIO1 mRNA CTD PMID:21878386 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Egr3 early growth response 3 multiple interactions ISO perfluorobutyric acid inhibits the reaction [Estradiol results in increased expression of EGR3 mRNA] CTD PMID:33111528 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression
multiple interactions		 ISO
EXP		 perfluorobutyric acid results in increased expression of EHHADH mRNA
perfluorobutyric acid affects the reaction [perfluorooctanoic acid results in increased expression of EHHADH mRNA]		 CTD PMID:23567314 PMID:34474067 PMID:34695511 PMID:35337807 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [perfluorooctanoic acid co-treated with perfluorobutyric acid co-treated with perfluorotetradecanoic acid] results in increased expression of EIF4EBP1 protein CTD PMID:37806615 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO perfluorobutyric acid results in increased expression of ERN1 mRNA CTD PMID:36251517 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO perfluorobutyric acid binds to [ESR1 protein binds to Estradiol] CTD PMID:33111528 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 increases expression ISO perfluorobutyric acid results in increased expression of EXTL1 mRNA CTD PMID:36251517 NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression
affects expression		 ISO perfluorobutyric acid results in increased expression of FABP1 mRNA
perfluorobutyric acid affects the expression of FABP1 mRNA		 CTD PMID:23567314 PMID:34474067 PMID:36251517 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO perfluorobutyric acid results in increased expression of FABP5 mRNA CTD PMID:34474067 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773 		JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions
affects expression		 EXP
ISO		 perfluorobutyric acid analog results in increased expression of FASN mRNA
[perfluorooctanoic acid co-treated with perfluorobutyric acid co-treated with perfluorotetradecanoic acid] results in decreased expression of FASN protein
perfluorobutyric acid affects the expression of FASN mRNA
perfluorobutyric acid results in increased expression of FASN mRNA		 CTD PMID:21878386 PMID:34474067 PMID:35337807 PMID:36251517 PMID:37806615 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression EXP perfluorobutyric acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fgf23 fibroblast growth factor 23 increases expression ISO perfluorobutyric acid results in increased expression of FGF23 mRNA CTD PMID:36251517 NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO perfluorobutyric acid results in increased expression of GADD45A mRNA CTD PMID:34474067 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 increases expression ISO perfluorobutyric acid results in increased expression of GAL3ST1 mRNA CTD PMID:36251517 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO perfluorobutyric acid results in increased expression of GCLC mRNA CTD PMID:34474067 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO perfluorobutyric acid results in increased expression of GPAM mRNA CTD PMID:35337807 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO perfluorobutyric acid results in increased expression of GSR mRNA CTD PMID:34474067 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP perfluorobutyric acid results in decreased expression of HADHA mRNA CTD PMID:22071372 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression EXP perfluorobutyric acid results in decreased expression of HADHB mRNA CTD PMID:22071372 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hbq1b hemoglobin subunit theta 1B increases expression ISO perfluorobutyric acid results in increased expression of HBQ1 mRNA CTD PMID:36251517 NCBI chr10:15,334,293...15,336,061
Ensembl chr10:15,320,762...15,321,397
Ensembl chr10:15,320,762...15,321,397 		JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP perfluorobutyric acid results in decreased expression of HHEX mRNA CTD PMID:22071372 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO perfluorobutyric acid results in increased expression of HMGCS1 mRNA CTD PMID:35337807 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hpn hepsin increases expression ISO perfluorobutyric acid results in increased expression of HPN mRNA CTD PMID:34474067 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO perfluorobutyric acid results in increased expression of HSPA5 mRNA CTD PMID:36251517 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO perfluorobutyric acid results in decreased expression of IL1B mRNA CTD PMID:36251517 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il24 interleukin 24 increases expression ISO perfluorobutyric acid results in increased expression of IL24 mRNA CTD PMID:36251517 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il6 interleukin 6 increases expression ISO perfluorobutyric acid results in increased expression of IL6 mRNA CTD PMID:36251517 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ipo4 importin 4 increases expression ISO perfluorobutyric acid results in increased expression of IPO4 mRNA CTD PMID:34474067 NCBI chr15:29,117,365...29,127,382
Ensembl chr15:29,117,365...29,127,285 		JBrowse link
G Krt18 keratin 18 increases expression ISO perfluorobutyric acid results in increased expression of KRT18 mRNA CTD PMID:34474067 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Krt7 keratin 7 increases expression ISO perfluorobutyric acid results in increased expression of KRT7 mRNA CTD PMID:36251517 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Krt8 keratin 8 increases expression ISO perfluorobutyric acid results in increased expression of KRT8 mRNA CTD PMID:34474067 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Lpl lipoprotein lipase increases expression ISO perfluorobutyric acid results in increased expression of LPL mRNA CTD PMID:34474067 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lss lanosterol synthase increases expression ISO perfluorobutyric acid results in increased expression of LSS mRNA CTD PMID:34474067 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Mal mal, T-cell differentiation protein increases expression EXP perfluorobutyric acid analog results in increased expression of MAL mRNA CTD PMID:21878386 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO [perfluorooctanoic acid co-treated with perfluorobutyric acid co-treated with perfluorotetradecanoic acid] results in increased expression of MAP1LC3B protein CTD PMID:37806615 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO perfluorobutyric acid results in increased expression of MTTP mRNA CTD PMID:35337807 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Myl10 myosin light chain 10 decreases expression ISO perfluorobutyric acid results in decreased expression of MYL10 mRNA CTD PMID:36251517 NCBI chr12:19,969,174...19,982,627
Ensembl chr12:19,970,055...19,978,614 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO perfluorobutyric acid results in decreased expression of NOS2 mRNA CTD PMID:23567314 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO perfluorobutyric acid results in increased expression of NQO1 mRNA CTD PMID:34474067 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
increases expression		 ISO perfluorobutyric acid results in increased activity of NR1I2 protein
perfluorobutyric acid results in increased expression of NR1I2 mRNA		 CTD PMID:28115241 PMID:35337807 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression ISO perfluorobutyric acid results in increased expression of NR1I3 mRNA CTD PMID:35337807 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression ISO perfluorobutyric acid results in decreased expression of NUPR1 mRNA CTD PMID:36251517 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Osmr oncostatin M receptor increases expression ISO perfluorobutyric acid results in increased expression of OSMR mRNA CTD PMID:34474067 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262 		JBrowse link
G Pax8 paired box 8 increases expression EXP perfluorobutyric acid results in increased expression of PAX8 mRNA CTD PMID:22071372 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP perfluorobutyric acid analog results in increased expression of PCNA mRNA CTD PMID:21878386 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluorobutyric acid results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 increases expression ISO perfluorobutyric acid results in increased expression of PIK3C3 mRNA CTD PMID:37806615 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048 		JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluorobutyric acid results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Pltp phospholipid transfer protein increases expression ISO perfluorobutyric acid results in increased expression of PLTP mRNA CTD PMID:34474067 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP perfluorobutyric acid analog results in increased expression of POR mRNA CTD PMID:21878386 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity
increases expression
decreases expression
affects response to substance		 ISO perfluorobutyric acid results in increased activity of PPARA protein
perfluorobutyric acid results in increased expression of PPARA protein
perfluorobutyric acid results in decreased expression of PPARA mRNA
PPARA protein affects the susceptibility to perfluorobutyric acid		 CTD PMID:19359353 PMID:23391484 PMID:28857218 PMID:34474067 PMID:37806615 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity
multiple interactions
increases expression		 ISO perfluorobutyric acid results in increased activity of PPARG protein
[perfluorooctanoic acid co-treated with perfluorobutyric acid co-treated with perfluorotetradecanoic acid] results in decreased expression of PPARG protein
perfluorobutyric acid results in increased expression of PPARG mRNA		 CTD PMID:24998974 PMID:37806615 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO perfluorobutyric acid binds to and results in decreased activity of PTPN11 protein CTD PMID:27572461 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 increases expression ISO perfluorobutyric acid results in increased expression of HLA-DRB1 mRNA CTD PMID:36251517 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G S100a7a S100 calcium binding protein A7A increases expression ISO perfluorobutyric acid results in increased expression of S100A7A mRNA CTD PMID:34474067 NCBI chr 2:176,151,405...176,155,846
Ensembl chr 2:176,151,288...176,156,441 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression
multiple interactions
affects expression		 ISO perfluorobutyric acid results in increased expression of SCD1 mRNA
[perfluorooctanoic acid co-treated with perfluorobutyric acid co-treated with perfluorotetradecanoic acid] results in decreased expression of SCD protein
perfluorobutyric acid affects the expression of SCD1 mRNA
perfluorobutyric acid results in increased expression of SCD mRNA; perfluorobutyric acid results in increased expression of SCD protein		 CTD PMID:23567314 PMID:34474067 PMID:35337807 PMID:36251517 PMID:37806615 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sdc2 syndecan 2 decreases expression ISO perfluorobutyric acid results in decreased expression of SDC2 mRNA CTD PMID:36251517 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081 		JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO perfluorobutyric acid results in increased expression of SERPINB2 mRNA CTD PMID:36251517 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO perfluorobutyric acid results in increased expression of SERPINE1 mRNA CTD PMID:34474067 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO perfluorobutyric acid results in increased expression of SOD1 mRNA CTD PMID:35337807 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Spp1 secreted phosphoprotein 1 affects expression ISO perfluorobutyric acid affects the expression of SPP1 mRNA CTD PMID:36251517 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression
multiple interactions		 ISO perfluorobutyric acid results in increased expression of SREBF1 mRNA; perfluorobutyric acid results in increased expression of SREBF1 protein
[perfluorooctanoic acid co-treated with perfluorobutyric acid co-treated with perfluorotetradecanoic acid] results in decreased expression of SREBF1 protein		 CTD PMID:35337807 PMID:36251517 PMID:37806615 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Susd2 sushi domain containing 2 decreases expression ISO perfluorobutyric acid results in decreased expression of SUSD2 mRNA CTD PMID:36251517 NCBI chr20:13,017,516...13,024,820
Ensembl chr20:13,017,477...13,024,903 		JBrowse link
G Tf transferrin decreases expression ISO perfluorobutyric acid results in decreased expression of TF mRNA CTD PMID:36251517 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO perfluorobutyric acid inhibits the reaction [Estradiol results in increased expression of TFF1 mRNA] CTD PMID:33111528 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Thrsp thyroid hormone responsive increases expression EXP perfluorobutyric acid analog results in increased expression of THRSP mRNA CTD PMID:21878386 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO perfluorobutyric acid results in increased expression of TIMP2 mRNA CTD PMID:36251517 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression ISO perfluorobutyric acid results in decreased expression of TIMP3 mRNA CTD PMID:36251517 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tmem52b transmembrane protein 52B decreases expression ISO perfluorobutyric acid results in decreased expression of TMEM52B mRNA CTD PMID:36251517 NCBI chr 4:162,954,025...162,959,220
Ensembl chr 4:162,954,025...162,959,220 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO perfluorobutyric acid results in increased expression of TNF mRNA CTD PMID:36251517 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tslp thymic stromal lymphopoietin increases expression ISO perfluorobutyric acid results in increased expression of TSLP mRNA CTD PMID:34474067 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Ttr transthyretin multiple interactions ISO perfluorobutyric acid affects the reaction [Thyroxine binds to TTR protein] CTD PMID:27528273 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO perfluorobutyric acid results in decreased expression of TXNIP mRNA CTD PMID:23567314 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP perfluorobutyric acid analog results in increased expression of UGT1A1 mRNA CTD PMID:21878386 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Zbtb7c zinc finger and BTB domain containing 7C decreases expression ISO perfluorobutyric acid results in decreased expression of ZBTB7C mRNA CTD PMID:36251517 NCBI chr18:69,441,616...69,765,744
Ensembl chr18:69,441,616...69,765,297 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19893
      application 19734
        reagent 18087
          chromatographic reagent 185
            1-fluoro-2,4-dinitrobenzene 82
            1-hexanesulfonic acid 0
            N,N-dimethylformamide dimethyl acetal 0
            N,O-bis(trimethylsilyl)trifluoroacetamide 0
            N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide 0
            N-(trimethylsilyl)diethylamine 0
            N-methyl-N-(trimethylsilyl)trifluoroacetamide 0
            N-trimethylsilylimidazole 0
            chlorotrimethylsilane 0
            heptafluorobutyric anhydride 0
            hexamethyldisilazane 0
            pentafluorobenzoyl chloride 0
            perfluorobutyric acid 110
            tert-butyldimethylsilyl chloride 0
            trimethylphenylammonium hydroxide 0
paths to the root