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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1318459 | 6480464 | Ethinyl Estradiol results in increased expression of SUSD2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1318459 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SUSD2 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RGD:1318458 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of SUSD2 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1318459 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SUSD2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SUSD2 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SUSD2 mRNA | CTD | PMID:22298810 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:1318459 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of SUSD2 mRNA | CTD | PMID:26251327 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | RGD:1318459 | 6480464 | 4, 4'-diaminodiphenylmethane results in decreased expression of SUSD2 mRNA | CTD | PMID:18648102 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1318459 | 6480464 | Fenretinide results in increased expression of SUSD2 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SUSD2 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of SUSD2 mRNA | CTD | PMID:31881176 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of SUSD2 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | RGD:1318458 | 6480464 | Aflatoxin B1 results in decreased methylation of SUSD2 3' UTR | CTD | PMID:30157460 | aristolochic acid A | increases expression | ISO | RGD:1318458 | 6480464 | aristolochic acid I results in increased expression of SUSD2 mRNA | CTD | PMID:33212167 | arsenite(3-) | increases expression | ISO | RGD:1318458 | 6480464 | arsenite results in increased expression of SUSD2 mRNA | CTD | PMID:23974009 | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SUSD2 mRNA | CTD | PMID:33854195 | benzo[a]pyrene | multiple interactions | ISO | RGD:1318459 | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of SUSD2 mRNA], Benzo(a)pyrene promotes the reaction [AHR protein binds to SUSD2 promoter] | CTD | PMID:19654925, PMID:22228805 | benzo[a]pyrene | increases expression | ISO | RGD:1318458 | 6480464 | Benzo(a)pyrene results in increased expression of SUSD2 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | RGD:1318458 | 6480464 | Benzo(a)pyrene affects the methylation of SUSD2 5' UTR, Benzo(a)pyrene affects the methylation of SUSD2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | RGD:1318458 | 6480464 | Benzo(a)pyrene results in increased methylation of SUSD2 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | RGD:1318459 | 6480464 | Benzo(a)pyrene results in increased expression of SUSD2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | RGD:1318459 | 6480464 | Benzo(a)pyrene results in decreased expression of SUSD2 mRNA | CTD | PMID:20127859 | beta-damascenone | increases expression | ISO | RGD:1318459 | 6480464 | beta-damascenone results in increased expression of SUSD2 mRNA | CTD | PMID:22982537 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:1318458 | 6480464 | Diethylhexyl Phthalate results in increased expression of SUSD2 mRNA | CTD | PMID:31163220 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in decreased expression of SUSD2 mRNA | CTD | PMID:26496021 | bisphenol A | increases expression | ISO | RGD:1318459 | 6480464 | bisphenol A results in increased expression of SUSD2 mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SUSD2 mRNA | CTD | PMID:25181051 more ... | cadmium atom | multiple interactions | ISO | RGD:1318458 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SUSD2 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | RGD:1318458 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SUSD2 mRNA | CTD | PMID:35301059 | carbamazepine | affects expression | ISO | RGD:1318458 | 6480464 | Carbamazepine affects the expression of SUSD2 mRNA | CTD | PMID:25979313 | cefaloridine | decreases expression | EXP | | 6480464 | Cephaloridine results in decreased expression of SUSD2 mRNA | CTD | PMID:18500788 | chlormequat chloride | increases expression | EXP | | 6480464 | Chlormequat results in increased expression of SUSD2 protein | CTD | PMID:34958886 | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SUSD2 mRNA | CTD | PMID:33854195 | choline | multiple interactions | ISO | RGD:1318459 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SUSD2 mRNA | CTD | PMID:20938992 | chromium(6+) | affects expression | ISO | RGD:1318459 | 6480464 | chromium hexavalent ion affects the expression of SUSD2 mRNA | CTD | PMID:28472532 | cisplatin | multiple interactions | ISO | RGD:1318458 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of SUSD2 mRNA | CTD | PMID:27392435 | copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of SUSD2 mRNA | CTD | PMID:30556269 | copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of SUSD2 mRNA | CTD | PMID:30556269 | dexamethasone | increases expression | ISO | RGD:1318458 | 6480464 | Dexamethasone results in increased expression of SUSD2 mRNA | CTD | PMID:25047013 | dorsomorphin | multiple interactions | ISO | RGD:1318458 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | RGD:1318458 | 6480464 | Doxorubicin results in increased expression of SUSD2 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of SUSD2 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | RGD:1318458 | 6480464 | entinostat results in increased expression of SUSD2 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | RGD:1318458 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SUSD2 mRNA | CTD | PMID:27188386 | ethanol | affects expression | ISO | RGD:1318459 | 6480464 | Ethanol affects the expression of SUSD2 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | RGD:1318459 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SUSD2 mRNA | CTD | PMID:20938992 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of SUSD2 mRNA | CTD | PMID:25539665 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SUSD2 mRNA | CTD | PMID:33387578 | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SUSD2 mRNA | CTD | PMID:33854195 | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SUSD2 mRNA | CTD | PMID:33854195 | L-methionine | multiple interactions | ISO | RGD:1318459 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SUSD2 mRNA | CTD | PMID:20938992 | nickel atom | decreases expression | ISO | RGD:1318458 | 6480464 | Nickel results in decreased expression of SUSD2 mRNA | CTD | PMID:24768652, PMID:25583101 | panobinostat | multiple interactions | ISO | RGD:1318458 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SUSD2 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | RGD:1318458 | 6480464 | panobinostat results in increased expression of SUSD2 mRNA | CTD | PMID:26272509 | paracetamol | affects expression | ISO | RGD:1318459 | 6480464 | Acetaminophen affects the expression of SUSD2 mRNA | CTD | PMID:17562736 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of SUSD2 mRNA | CTD | PMID:32680482 | pirinixic acid | decreases expression | ISO | RGD:1318459 | 6480464 | pirinixic acid results in decreased expression of SUSD2 mRNA | CTD | PMID:17426115, PMID:20813756 | potassium dichromate | increases expression | ISO | RGD:1318459 | 6480464 | Potassium Dichromate results in increased expression of SUSD2 mRNA | CTD | PMID:23608068 | propanal | increases expression | ISO | RGD:1318458 | 6480464 | propionaldehyde results in increased expression of SUSD2 mRNA | CTD | PMID:26079696 | resveratrol | multiple interactions | ISO | RGD:1318458 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SUSD2 mRNA | CTD | PMID:23557933 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of SUSD2 mRNA | CTD | PMID:28374803 | SB 431542 | multiple interactions | ISO | RGD:1318458 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | RGD:1318458 | 6480464 | sodium arsenite results in increased expression of SUSD2 mRNA | CTD | PMID:34032870 | testosterone | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in decreased expression of SUSD2 mRNA | CTD | PMID:26496021 | tetrachloromethane | affects expression | ISO | RGD:1318459 | 6480464 | Carbon Tetrachloride affects the expression of SUSD2 mRNA | CTD | PMID:17484886 | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SUSD2 mRNA | CTD | PMID:33854195 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SUSD2 mRNA | CTD | PMID:23411599 | titanium dioxide | decreases expression | ISO | RGD:1318459 | 6480464 | titanium dioxide results in decreased expression of SUSD2 mRNA | CTD | PMID:23409001 | triclosan | increases expression | ISO | RGD:1318458 | 6480464 | Triclosan results in increased expression of SUSD2 mRNA | CTD | PMID:30510588 | Triptolide | decreases expression | EXP | | 6480464 | triptolide results in decreased expression of SUSD2 protein | CTD | PMID:32519852 | triptonide | increases expression | ISO | RGD:1318459 | 6480464 | triptonide results in increased expression of SUSD2 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | ISO | RGD:1318458 | 6480464 | Valproic Acid results in increased methylation of SUSD2 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | RGD:1318458 | 6480464 | Valproic Acid affects the expression of SUSD2 mRNA | CTD | PMID:25979313 | vancomycin | increases expression | ISO | RGD:1318459 | 6480464 | Vancomycin results in increased expression of SUSD2 mRNA | CTD | PMID:18930951 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of SUSD2 mRNA | CTD | PMID:23034163 | |