|
G |
ACE |
angiotensin I converting enzyme |
multiple interactions |
ISO |
Lycopene inhibits the reaction [bisphenol A results in decreased activity of ACE protein] |
CTD |
PMID:32153214 |
|
NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
|
|
G |
ACHE |
acetylcholinesterase (Yt blood group) |
multiple interactions |
ISO |
Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of ACHE protein] |
CTD |
PMID:22192907 PMID:26900785 |
|
NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
|
|
G |
ACVR2B |
activin A receptor type 2B |
decreases expression |
ISO |
Lycopene results in decreased expression of SCGB2A2 mRNA |
CTD |
PMID:15084515 |
|
NCBI chr 3:38,453,890...38,493,142
Ensembl chr 3:38,453,890...38,493,142
|
|
G |
ADD1 |
adducin 1 |
decreases expression |
EXP |
lycopene results in decreased expression of ADD1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076
|
|
G |
AGER |
advanced glycosylation end-product specific receptor |
multiple interactions |
EXP |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein] |
CTD |
PMID:22429818 |
|
NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
|
|
G |
AHR |
aryl hydrocarbon receptor |
decreases expression multiple interactions |
EXP ISO |
lycopene results in decreased expression of AHR mRNA [Lycopene co-treated with Atrazine] results in increased expression of AHR mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of AHR protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of AHR mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of AHR protein] |
CTD |
PMID:16886892 PMID:36216167 PMID:36403809 |
|
NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
|
|
G |
AIF1 |
allograft inflammatory factor 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] |
CTD |
PMID:28974442 |
|
NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021
|
|
G |
AKT1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation |
EXP |
lycopene results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:17337101 |
|
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
|
|
G |
ALAD |
aminolevulinate dehydratase |
multiple interactions |
ISO |
lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein] lycopene inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein] |
CTD |
PMID:17516994 PMID:25682699 |
|
NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
|
|
G |
AQP1 |
aquaporin 1 (Colton blood group) |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of AQP1 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
|
|
G |
AQP11 |
aquaporin 11 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP11 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr11:77,589,953...77,610,356
Ensembl chr11:77,589,391...77,610,356
|
|
G |
AQP2 |
aquaporin 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 protein] |
CTD |
PMID:33960999 |
|
NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878
|
|
G |
AQP4 |
aquaporin 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP4 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771
|
|
G |
AQP6 |
aquaporin 6 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP6 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr12:49,972,947...49,977,139
Ensembl chr12:49,967,194...49,977,139
|
|
G |
AQP7 |
aquaporin 7 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP7 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr 9:33,383,191...33,402,568
Ensembl chr 9:33,383,179...33,402,682
|
|
G |
AR |
androgen receptor |
decreases expression |
EXP |
lycopene results in decreased expression of AR mRNA |
CTD |
PMID:16886892 |
|
NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
|
|
G |
ARNT |
aryl hydrocarbon receptor nuclear translocator |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of ARNT mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT protein] |
CTD |
PMID:36216167 PMID:36403809 |
|
NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708
|
|
G |
ATF6 |
activating transcription factor 6 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ATF6 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
|
|
G |
ATG10 |
autophagy related 10 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG10 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 5:81,972,023...82,256,133
Ensembl chr 5:81,972,023...82,276,857
|
|
G |
ATG13 |
autophagy related 13 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG13 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr11:46,617,553...46,674,518
Ensembl chr11:46,617,527...46,674,818
|
|
G |
ATG14 |
autophagy related 14 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG14 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr14:55,366,391...55,411,830
Ensembl chr14:55,366,391...55,411,830
|
|
G |
ATG16L1 |
autophagy related 16 like 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG16L1 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 2:233,251,673...233,295,669
Ensembl chr 2:233,210,051...233,295,674
|
|
G |
ATG16L2 |
autophagy related 16 like 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG16L2 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr11:72,814,411...72,843,740
Ensembl chr11:72,814,406...72,843,674
|
|
G |
ATG2B |
autophagy related 2B |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG2B mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr14:96,279,195...96,363,341
Ensembl chr14:96,279,195...96,363,341
|
|
G |
ATG3 |
autophagy related 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG3 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 3:112,532,510...112,561,962
Ensembl chr 3:112,532,510...112,562,046
|
|
G |
ATG4A |
autophagy related 4A cysteine peptidase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4A mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr X:108,088,829...108,154,671
Ensembl chr X:108,091,668...108,154,671
|
|
G |
ATG4B |
autophagy related 4B cysteine peptidase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG4B mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 2:241,637,693...241,673,857
Ensembl chr 2:241,637,213...241,673,857
|
|
G |
ATG4C |
autophagy related 4C cysteine peptidase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4C mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 1:62,784,132...62,865,516
Ensembl chr 1:62,784,132...62,865,516
|
|
G |
ATG5 |
autophagy related 5 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG5 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
|
|
G |
ATG7 |
autophagy related 7 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG7 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
|
|
G |
ATG9A |
autophagy related 9A |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9A mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 2:219,219,380...219,229,636
Ensembl chr 2:219,219,380...219,229,717
|
|
G |
ATG9B |
autophagy related 9B |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9B mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 7:151,012,209...151,024,499
Ensembl chr 7:151,012,209...151,024,499
|
|
G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1A1 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
|
|
G |
ATP1A2 |
ATPase Na+/K+ transporting subunit alpha 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A2 mRNA] |
CTD |
PMID:27112537 PMID:33960999 |
|
NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
|
|
G |
ATP1A3 |
ATPase Na+/K+ transporting subunit alpha 3 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A3 mRNA] |
CTD |
PMID:26476475 |
|
NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497
|
|
G |
ATP1A4 |
ATPase Na+/K+ transporting subunit alpha 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A4 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr 1:160,151,603...160,186,980
Ensembl chr 1:160,151,586...160,186,980
|
|
G |
ATP1B1 |
ATPase Na+/K+ transporting subunit beta 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B1 mRNA] |
CTD |
PMID:27112537 PMID:33960999 |
|
NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
|
|
G |
ATP1B2 |
ATPase Na+/K+ transporting subunit beta 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP1B2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B2 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
|
|
G |
ATP1B3 |
ATPase Na+/K+ transporting subunit beta 3 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine affects the expression of ATP1B3 mRNA] |
CTD |
PMID:26476475 |
|
NCBI chr 3:141,876,643...141,926,549
Ensembl chr 3:141,876,124...141,926,549
|
|
G |
ATP1B4 |
ATPase Na+/K+ transporting family member beta 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1B4 mRNA] |
CTD |
PMID:26476475 PMID:33960999 |
|
NCBI chr X:120,362,089...120,383,237
Ensembl chr X:120,362,085...120,383,249
|
|
G |
ATP2A1 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A1 mRNA] |
CTD |
PMID:27112537 |
|
NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
|
|
G |
ATP2A2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A2 mRNA] |
CTD |
PMID:27112537 PMID:33960999 |
|
NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
|
|
G |
ATP2A3 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2A3 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A3 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,870...3,964,464
|
|
G |
ATP2B1 |
ATPase plasma membrane Ca2+ transporting 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2B1 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366
|
|
G |
ATP2B2 |
ATPase plasma membrane Ca2+ transporting 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B2 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007
|
|
G |
ATP2B3 |
ATPase plasma membrane Ca2+ transporting 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B3 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr X:153,517,642...153,582,929
Ensembl chr X:153,517,642...153,582,939
|
|
G |
ATP2B4 |
ATPase plasma membrane Ca2+ transporting 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B4 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081
|
|
G |
ATP2C1 |
ATPase secretory pathway Ca2+ transporting 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2C1 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr 3:130,850,595...131,016,712
Ensembl chr 3:130,850,595...131,016,712
|
|
G |
ATP2C2 |
ATPase secretory pathway Ca2+ transporting 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2C2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C2 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr16:84,368,538...84,464,187
Ensembl chr16:84,368,527...84,464,187
|
|
G |
BACH1 |
BTB domain and CNC homolog 1 |
increases expression |
EXP |
lycopene results in increased expression of BACH1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr21:29,298,922...29,361,894
Ensembl chr21:29,194,071...29,630,751
|
|
G |
BAK1 |
BCL2 antagonist/killer 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAK1 protein] |
CTD |
PMID:36583613 |
|
NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
|
|
G |
BAP1 |
BRCA1 associated protein 1 |
increases expression |
EXP |
lycopene results in increased expression of BAP1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008
|
|
G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA] Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein]; Lycopene inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of BAX mRNA] |
CTD |
PMID:26900785 PMID:27871895 PMID:31568845 PMID:32153214 PMID:36583613 |
|
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
|
|
G |
BCHE |
butyrylcholinesterase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of BCHE protein] |
CTD |
PMID:26900785 |
|
NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
|
|
G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions increases expression |
ISO |
[S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in decreased expression of BCL2 mRNA] Lycopene results in increased expression of BCL2 mRNA lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA] |
CTD |
PMID:16030430 PMID:26900785 PMID:27871895 PMID:31568845 PMID:32153214 |
|
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
|
|
G |
BCO1 |
beta-carotene oxygenase 1 |
multiple interactions |
ISO |
BCO1 affects the reaction [lycopene results in decreased abundance of Testosterone] |
CTD |
PMID:21935922 |
|
NCBI chr16:81,238,689...81,291,142
Ensembl chr16:81,238,689...81,291,142
|
|
G |
BDNF |
brain derived neurotrophic factor |
multiple interactions |
ISO |
lycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]; lycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein] Lycopene inhibits the reaction [bisphenol A results in decreased expression of BDNF protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased expression of BDNF protein] |
CTD |
PMID:28974442 PMID:32153214 PMID:32544411 |
|
NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
|
|
G |
BECN1 |
beclin 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of BECN1 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
|
|
G |
BRAF |
B-Raf proto-oncogene, serine/threonine kinase |
decreases expression |
EXP |
lycopene results in decreased expression of BRAF protein |
CTD |
PMID:17337101 |
|
NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
|
|
G |
C1QA |
complement C1q A chain |
decreases expression |
ISO |
lycopene results in decreased expression of C1QA mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678
|
|
G |
C4B |
complement C4B (Chido/Rodgers blood group) |
decreases expression |
ISO |
lycopene results in decreased expression of C4B mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
|
|
G |
CALCA |
calcitonin related polypeptide alpha |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of CALCA protein] |
CTD |
PMID:33592256 |
|
NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354
|
|
G |
CASP1 |
caspase 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP1 protein] |
CTD |
PMID:36610486 |
|
NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
|
|
G |
CASP3 |
caspase 3 |
multiple interactions |
ISO |
[S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; Lycopene inhibits the reaction [bisphenol A results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA] Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA] |
CTD |
PMID:16030430 PMID:27102619 PMID:27871895 PMID:31568845 PMID:32153214 PMID:32544411 PMID:36583613 More...
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP8 |
caspase 8 |
multiple interactions decreases expression |
ISO EXP |
[S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein] lycopene results in decreased expression of CASP8 mRNA |
CTD |
PMID:16030430 PMID:16886892 |
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NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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G |
CASP9 |
caspase 9 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP9 protein]; lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA] |
CTD |
PMID:27871895 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CAT |
catalase |
multiple interactions decreases expression increases activity increases expression |
ISO EXP |
Lycopene affects the reaction [Doxorubicin affects the activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Cadmium Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Mercuric Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA] Lycopene results in decreased expression of CAT mRNA Lycopene affects the reaction [Atrazine affects the expression of CAT mRNA]; Lycopene inhibits the reaction [Acetaminophen results in increased activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT protein] lycopene results in increased activity of CAT protein lycopene results in increased expression of CAT |
CTD |
PMID:16325981 PMID:17516994 PMID:17873360 PMID:19450652 PMID:20074268 PMID:26900785 PMID:27102619 PMID:27989599 PMID:30360616 PMID:31568845 PMID:32544411 PMID:35917956 PMID:36216167 PMID:36610486 More...
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CCL4 |
C-C motif chemokine ligand 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL4 mRNA] |
CTD |
PMID:36583613 |
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NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
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G |
CCL5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL5 mRNA] |
CTD |
PMID:36583613 |
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NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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G |
CCND1 |
cyclin D1 |
multiple interactions decreases expression |
EXP ISO |
Lycopene inhibits the reaction [Genistein results in increased expression of CCND1 protein]; Lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein] lycopene results in decreased expression of CCND1 protein lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein] |
CTD |
PMID:16565789 PMID:17051425 PMID:17337101 PMID:19551842 |
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NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G |
CCNE1 |
cyclin E1 |
decreases expression increases expression |
EXP |
lycopene results in decreased expression of CCNE1 protein lycopene results in increased expression of CCNE1 mRNA |
CTD |
PMID:16886892 PMID:17337101 |
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NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
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G |
CDK1 |
cyclin dependent kinase 1 |
decreases expression |
EXP |
lycopene results in decreased expression of CDK1 protein |
CTD |
PMID:17337101 |
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NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
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G |
CDK4 |
cyclin dependent kinase 4 |
decreases expression |
EXP |
lycopene results in decreased expression of CDK4 protein |
CTD |
PMID:17337101 |
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NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
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G |
CDK5 |
cyclin dependent kinase 5 |
decreases expression |
EXP |
lycopene results in decreased expression of CDK5 protein |
CTD |
PMID:17337101 |
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NCBI chr 7:151,053,815...151,057,897
Ensembl chr 7:151,053,815...151,057,897
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G |
CDK7 |
cyclin dependent kinase 7 |
decreases expression |
EXP |
lycopene results in decreased expression of CDK7 protein |
CTD |
PMID:17337101 |
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NCBI chr 5:69,234,795...69,277,430
Ensembl chr 5:69,234,795...69,277,430
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G |
CDK9 |
cyclin dependent kinase 9 |
decreases expression |
EXP |
lycopene results in decreased expression of CDK9 protein |
CTD |
PMID:17337101 |
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NCBI chr 9:127,786,034...127,790,792
Ensembl chr 9:127,785,679...127,790,792
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G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
multiple interactions |
EXP |
lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein] |
CTD |
PMID:16565789 |
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NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
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G |
CGAS |
cyclic GMP-AMP synthase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS protein] |
CTD |
PMID:36583613 |
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NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297
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G |
CHGA |
chromogranin A |
increases expression |
EXP |
lycopene results in increased expression of CHGA mRNA |
CTD |
PMID:16886892 |
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NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285
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G |
CHGB |
chromogranin B |
decreases expression |
EXP |
lycopene results in decreased expression of CHGB mRNA |
CTD |
PMID:16886892 |
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NCBI chr20:5,911,510...5,925,353
Ensembl chr20:5,911,510...5,925,353
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G |
CKB |
creatine kinase B |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CKB protein] |
CTD |
PMID:26900785 |
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NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
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G |
CRB1 |
crumbs cell polarity complex component 1 |
decreases expression |
EXP |
lycopene results in decreased expression of CRB1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 1:197,201,504...197,478,455
Ensembl chr 1:197,268,204...197,478,455
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G |
CREB1 |
cAMP responsive element binding protein 1 |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of CREB1 protein Lycopene inhibits the reaction [bisphenol A results in decreased expression of CREB1 protein] |
CTD |
PMID:32153214 |
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NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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G |
CSF2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CSF2 mRNA] |
CTD |
PMID:36583613 |
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NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
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G |
CST4 |
cystatin S |
decreases expression |
ISO |
Lycopene results in decreased expression of ANDPRO mRNA |
CTD |
PMID:15084515 |
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NCBI chr20:23,685,640...23,689,038
Ensembl chr20:23,685,640...23,689,038
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G |
CTSS |
cathepsin S |
decreases expression |
ISO |
lycopene results in decreased expression of CTSS mRNA |
CTD |
PMID:19555370 |
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NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957
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G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 protein] |
CTD |
PMID:36583613 |
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NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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G |
CXCL14 |
C-X-C motif chemokine ligand 14 |
decreases expression |
ISO |
lycopene results in decreased expression of CXCL14 mRNA |
CTD |
PMID:19555370 |
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NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279
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G |
CXCL2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL2 mRNA] |
CTD |
PMID:36583613 |
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NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA] |
CTD |
PMID:25551565 |
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NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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G |
CYB5A |
cytochrome b5 type A |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in increased expression of CYB5A protein] |
CTD |
PMID:26775023 |
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NCBI chr18:74,250,846...74,291,963
Ensembl chr18:74,250,846...74,291,973
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G |
CYP11A1 |
cytochrome P450 family 11 subfamily A member 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 protein] |
CTD |
PMID:19071209 |
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NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
decreases activity multiple interactions |
ISO |
lycopene results in decreased activity of CYP1A1 protein Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 protein] |
CTD |
PMID:19329757 PMID:26775023 PMID:36216167 PMID:36403809 |
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NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
multiple interactions increases expression |
ISO |
[Lycopene co-treated with Atrazine] results in increased expression of CYP1A2 mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A2 protein] Lycopene results in increased expression of CYP1A2 mRNA |
CTD |
PMID:26775023 PMID:36216167 PMID:36403809 |
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NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
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G |
CYP1B1 |
cytochrome P450 family 1 subfamily B member 1 |
decreases activity increases expression multiple interactions |
ISO |
lycopene results in decreased activity of CYP1B1 protein Lycopene results in increased expression of CYP1B1 mRNA [Lycopene co-treated with Atrazine] results in increased expression of CYP1B1 mRNA; Lycopene affects the reaction [Atrazine results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 protein] |
CTD |
PMID:19329757 PMID:26775023 PMID:36216167 PMID:36403809 |
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NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
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G |
CYP2A7 |
cytochrome P450 family 2 subfamily A member 7 |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine affects the expression of CYP2A4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2A4 mRNA] |
CTD |
PMID:26775023 PMID:36216167 |
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NCBI chr19:40,875,439...40,882,231
Ensembl chr19:40,875,439...40,882,752
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G |
CYP2B6 |
cytochrome P450 family 2 subfamily B member 6 |
multiple interactions |
ISO |
Lycopene promotes the reaction [Atrazine results in increased expression of CYP2B10 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
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G |
CYP2C8 |
cytochrome P450 family 2 subfamily C member 8 |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine results in increased expression of CYP2C29 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
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G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 protein] |
CTD |
PMID:26775023 PMID:36216167 PMID:36403809 |
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NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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G |
CYP2F1 |
cytochrome P450 family 2 subfamily F member 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2F2 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381
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G |
CYP3A4 |
cytochrome P450 family 3 subfamily A member 4 |
increases activity |
EXP |
lycopene results in increased activity of CYP3A4 protein |
CTD |
PMID:16632523 |
|
NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
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G |
CYP3A5 |
cytochrome P450 family 3 subfamily A member 5 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP3A13 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
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G |
CYP3A7 |
cytochrome P450 family 3 subfamily A member 7 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP3A13 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
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G |
CYP4A22 |
cytochrome P450 family 4 subfamily A member 22 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP4A31 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727
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G |
CYP4V2 |
cytochrome P450 family 4 subfamily V member 2 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP4V3 mRNA] Lycopene results in increased expression of CYP4V3 mRNA |
CTD |
PMID:36216167 |
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NCBI chr 4:186,191,567...186,213,463
Ensembl chr 4:186,191,567...186,213,463
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G |
CYP7B1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in increased expression of CYP7B1 mRNA] |
CTD |
PMID:26775023 |
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NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737
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G |
DDB2 |
damage specific DNA binding protein 2 |
increases expression |
EXP |
lycopene results in increased expression of DDB2 mRNA |
CTD |
PMID:16886892 |
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NCBI chr11:47,214,454...47,239,217
Ensembl chr11:47,214,465...47,239,217
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of EIF2AK3 mRNA] |
CTD |
PMID:32544411 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
EIF4G1 |
eukaryotic translation initiation factor 4 gamma 1 |
increases expression |
EXP |
lycopene results in increased expression of EIF4G1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 3:184,314,606...184,335,358
Ensembl chr 3:184,314,495...184,335,358
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
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G |
ESR1 |
estrogen receptor 1 |
multiple interactions increases expression |
EXP |
lycopene inhibits the reaction [Estradiol results in increased activity of ESR1 protein] lycopene results in increased expression of ESR1 mRNA |
CTD |
PMID:16886892 PMID:17051425 |
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NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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G |
ESR2 |
estrogen receptor 2 |
multiple interactions |
EXP |
lycopene inhibits the reaction [Estradiol results in increased activity of ESR2 protein] |
CTD |
PMID:17051425 |
|
NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
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G |
FANCC |
FA complementation group C |
decreases expression |
EXP |
lycopene results in decreased expression of FANCC mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 9:95,099,054...95,317,709
Ensembl chr 9:95,099,054...95,426,796
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G |
FANCF |
FA complementation group F |
decreases expression |
EXP |
lycopene results in decreased expression of FANCF mRNA |
CTD |
PMID:16886892 |
|
NCBI chr11:22,622,533...22,625,823
Ensembl chr11:22,622,533...22,625,823
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G |
FASLG |
Fas ligand |
decreases expression |
EXP |
lycopene results in decreased expression of FASLG mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
lycopene results in increased expression of FOS mRNA |
CTD |
PMID:16886892 |
|
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of GCLC mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLC mRNA] |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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G |
GCLM |
glutamate-cysteine ligase modifier subunit |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of GCLM protein Lycopene inhibits the reaction [Atrazine results in increased expression of GCLM mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLM mRNA] |
CTD |
PMID:35917956 PMID:36216167 |
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NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
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G |
GET1 |
guided entry of tail-anchored proteins factor 1 |
decreases expression |
EXP |
Lycopene results in decreased expression of GET1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr21:39,380,326...39,428,528
Ensembl chr21:39,377,698...39,428,528
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G |
GFAP |
glial fibrillary acidic protein |
decreases expression multiple interactions |
ISO |
lycopene results in decreased expression of GFAP mRNA Lycopene inhibits the reaction [Oxaliplatin results in increased expression of GFAP protein] |
CTD |
PMID:19555370 PMID:32544411 |
|
NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
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G |
GJA1 |
gap junction protein alpha 1 |
increases expression multiple interactions |
ISO |
lycopene results in increased expression of GJA1 protein Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of GJA1 protein] |
CTD |
PMID:16091010 PMID:31568845 |
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NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
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G |
GJA4 |
gap junction protein alpha 4 |
decreases expression |
EXP |
lycopene results in decreased expression of GJA4 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 1:34,792,999...34,795,747
Ensembl chr 1:34,792,999...34,795,747
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G |
GJA5 |
gap junction protein alpha 5 |
decreases expression increases expression |
EXP |
lycopene results in decreased expression of GJA5 mRNA lycopene results in increased expression of GJA5 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX1 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
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G |
GPX2 |
glutathione peroxidase 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX2 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
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G |
GPX3 |
glutathione peroxidase 3 |
multiple interactions increases expression |
ISO |
Lycopene affects the reaction [Atrazine affects the expression of GPX3 mRNA] Lycopene results in increased expression of GPX3 mRNA |
CTD |
PMID:36216167 |
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NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
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G |
GPX4 |
glutathione peroxidase 4 |
decreases expression multiple interactions |
EXP ISO |
lycopene results in decreased expression of GPX4 mRNA Lycopene affects the reaction [Atrazine affects the expression of GPX4 mRNA] |
CTD |
PMID:16886892 PMID:36216167 |
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NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791
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G |
GPX5 |
glutathione peroxidase 5 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX5 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr 6:28,525,881...28,534,955
Ensembl chr 6:28,525,881...28,534,955
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G |
GPX6 |
glutathione peroxidase 6 |
increases expression |
ISO |
Lycopene results in increased expression of GPX6 mRNA |
CTD |
PMID:36216167 |
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NCBI chr 6:28,503,296...28,515,793
Ensembl chr 6:28,503,296...28,528,215
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G |
GPX7 |
glutathione peroxidase 7 |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of GPX7 mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of GPX7 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr 1:52,602,371...52,609,051
Ensembl chr 1:52,602,371...52,609,051
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G |
GPX8 |
glutathione peroxidase 8 (putative) |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of GPX8 mRNA] Lycopene results in increased expression of GPX8 mRNA |
CTD |
PMID:36216167 |
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NCBI chr 5:55,160,171...55,167,297
Ensembl chr 5:55,160,167...55,167,297
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G |
GSDMD |
gasdermin D |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSDMD protein] |
CTD |
PMID:36610486 |
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NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
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G |
GSR |
glutathione-disulfide reductase |
multiple interactions |
ISO |
lycopene inhibits the reaction [Zearalenone results in decreased activity of GSR protein] |
CTD |
PMID:25682699 |
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NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
GSS |
glutathione synthetase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSS mRNA] |
CTD |
PMID:35917956 PMID:36610486 |
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NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
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G |
HMGB1 |
high mobility group box 1 |
multiple interactions decreases response to substance |
EXP |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased secretion of HMGB1 protein] lycopene results in decreased susceptibility to HMGB1 protein |
CTD |
PMID:22429818 |
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NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
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G |
HMOX1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO EXP |
lycopene results in increased expression of HMOX1 mRNA; lycopene results in increased expression of HMOX1 protein Lycopene inhibits the reaction [Atrazine results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of HMOX1 mRNA] [lycopene co-treated with Hydrogen Peroxide] results in increased expression of HMOX1 protein lycopene promotes the reaction [Atrazine results in increased expression of HMOX1 mRNA] |
CTD |
PMID:19551842 PMID:27102619 PMID:28974442 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 More...
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HSD3B1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of HSD3B1 protein] |
CTD |
PMID:19071209 |
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NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
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G |
HSPA4 |
heat shock protein family A (Hsp70) member 4 |
multiple interactions |
ISO |
lycopene inhibits the reaction [decamethrin results in increased expression of HSPA4 mRNA] |
CTD |
PMID:23076637 |
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NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of HSPA5 mRNA] |
CTD |
PMID:32544411 |
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NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
ICAM1 |
intercellular adhesion molecule 1 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; Lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; Lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] |
CTD |
PMID:22429818 PMID:25551565 |
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NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
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G |
IGF1 |
insulin like growth factor 1 |
multiple interactions decreases expression increases expression |
EXP ISO |
lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] lycopene results in decreased expression of IGF1 mRNA lycopene results in increased expression of IGF1 mRNA |
CTD |
PMID:15084515 PMID:16565789 PMID:16886892 |
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NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
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G |
IGF1R |
insulin like growth factor 1 receptor |
decreases expression |
EXP |
lycopene results in decreased expression of IGF1R protein |
CTD |
PMID:17337101 |
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NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
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G |
IGFBP2 |
insulin like growth factor binding protein 2 |
increases expression |
EXP |
lycopene results in increased expression of IGFBP2 protein |
CTD |
PMID:17337101 |
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NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436
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G |
IL10 |
interleukin 10 |
multiple interactions |
EXP ISO |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein] Lycopene inhibits the reaction [Atrazine results in decreased expression of IL10 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL10 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL10] |
CTD |
PMID:25551565 PMID:25682699 PMID:36216167 PMID:36583613 |
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NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
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G |
IL18 |
interleukin 18 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL18 protein] |
CTD |
PMID:36610486 |
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NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
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G |
IL1B |
interleukin 1 beta |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Galactose results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL1B] |
CTD |
PMID:25682699 PMID:28974442 PMID:36216167 PMID:36610486 |
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL2 |
interleukin 2 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Zearalenone results in increased expression of IL2] |
CTD |
PMID:25682699 |
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NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
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G |
IL6 |
interleukin 6 |
decreases expression multiple interactions |
ISO |
lycopene results in decreased expression of IL6 mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL6] |
CTD |
PMID:15084515 PMID:25682699 PMID:36216167 PMID:36583613 |
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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G |
IRF3 |
interferon regulatory factor 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of IRF3 protein] |
CTD |
PMID:36583613 |
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NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
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G |
IRF7 |
interferon regulatory factor 7 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF7 mRNA] |
CTD |
PMID:36583613 |
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NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983
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G |
IVL |
involucrin |
decreases expression |
EXP |
lycopene results in decreased expression of IVL protein |
CTD |
PMID:10769631 |
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NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886
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G |
JAK1 |
Janus kinase 1 |
increases expression |
EXP |
lycopene results in increased expression of JAK1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754
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G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
EXP |
lycopene results in decreased expression of JUN mRNA |
CTD |
PMID:16886892 |
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NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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G |
KEAP1 |
kelch like ECH associated protein 1 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of KEAP1 protein] Lycopene results in increased expression of KEAP1 mRNA |
CTD |
PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
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G |
KIF2A |
kinesin family member 2A |
increases expression |
EXP |
lycopene results in increased expression of KIF2A mRNA |
CTD |
PMID:16886892 |
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NCBI chr 5:62,306,206...62,391,025
Ensembl chr 5:62,306,162...62,391,025
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G |
KPNA2 |
karyopherin subunit alpha 2 |
increases expression |
EXP |
lycopene results in increased expression of KPNA2 mRNA |
CTD |
PMID:16886892 |
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NCBI chr17:68,035,735...68,046,854
Ensembl chr17:68,035,636...68,047,364
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G |
LDLR |
low density lipoprotein receptor |
increases expression |
EXP |
lycopene results in increased expression of LDLR mRNA |
CTD |
PMID:16886892 |
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NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
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G |
LIPA |
lipase A, lysosomal acid type |
increases expression |
EXP |
lycopene results in increased expression of LIPA mRNA |
CTD |
PMID:16886892 |
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NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557
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G |
LPO |
lactoperoxidase |
multiple interactions |
ISO |
lycopene inhibits the reaction [Diethylnitrosamine results in increased expression of LPO protein] |
CTD |
PMID:24144777 |
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NCBI chr17:58,238,584...58,268,518
Ensembl chr17:58,218,548...58,268,518
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G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased localization of MAP1LC3B protein] |
CTD |
PMID:36583613 |
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NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
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G |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
increases expression |
EXP |
lycopene results in increased expression of MAP2K1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
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G |
MAP2K2 |
mitogen-activated protein kinase kinase 2 |
decreases expression |
EXP |
lycopene results in decreased expression of MAP2K2 protein |
CTD |
PMID:17337101 |
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NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122
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G |
MAP2K4 |
mitogen-activated protein kinase kinase 4 |
decreases expression |
EXP |
lycopene results in decreased expression of MAP2K4 protein |
CTD |
PMID:17337101 |
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NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830
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G |
MAP2K6 |
mitogen-activated protein kinase kinase 6 |
decreases expression |
EXP |
lycopene results in decreased expression of MAP2K6 protein |
CTD |
PMID:17337101 |
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NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased phosphorylation of MAPK1 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of MAPK1 protein] Lycopene results in increased expression of MAPK1 protein Lycopene inhibits the reaction [Atrazine results in increased expression of MAPK1 mRNA] |
CTD |
PMID:19551842 PMID:30360616 PMID:32153214 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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G |
MAPK14 |
mitogen-activated protein kinase 14 |
decreases expression multiple interactions increases expression |
EXP ISO |
lycopene results in decreased expression of MAPK14 protein Lycopene inhibits the reaction [Oxaliplatin results in increased expression of MAPK14 protein] lycopene results in increased expression of MAPK14 mRNA |
CTD |
PMID:16886892 PMID:17337101 PMID:32544411 |
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NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
decreases expression |
EXP |
lycopene results in decreased expression of MAPK3 protein |
CTD |
PMID:17337101 |
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
MAPK8 |
mitogen-activated protein kinase 8 |
decreases expression |
EXP |
lycopene results in decreased expression of MAPK8 protein |
CTD |
PMID:17337101 |
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NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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G |
MGAT2 |
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
increases expression |
EXP |
lycopene results in increased expression of MGAT2 mRNA |
CTD |
PMID:16886892 |
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NCBI chr14:49,620,799...49,623,481
Ensembl chr14:49,620,799...49,623,481
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G |
MICA |
MHC class I polypeptide-related sequence A |
increases expression |
EXP |
lycopene results in increased expression of MICA mRNA |
CTD |
PMID:16886892 |
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NCBI chr 6:31,400,711...31,415,315
Ensembl chr 6:31,399,784...31,415,315
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G |
MKI67 |
marker of proliferation Ki-67 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of MKI67 protein] |
CTD |
PMID:33592256 |
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NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
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G |
MLH1 |
mutL homolog 1 |
increases expression |
EXP |
lycopene results in increased expression of MLH1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896
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G |
MMP2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Acetaminophen results in increased activity of MMP2 protein] |
CTD |
PMID:27989599 |
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NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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G |
MSH2 |
mutS homolog 2 |
increases expression |
EXP |
lycopene results in increased expression of MSH2 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 2:47,403,067...47,709,830
Ensembl chr 2:47,403,067...47,663,146
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G |
MSH6 |
mutS homolog 6 |
increases expression |
EXP |
lycopene results in increased expression of MSH6 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 2:47,783,145...47,810,101
Ensembl chr 2:47,695,530...47,810,063
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
increases expression multiple interactions |
ISO |
lycopene results in increased expression of NFE2L2 mRNA; lycopene results in increased expression of NFE2L2 protein Lycopene inhibits the reaction [Atrazine affects the localization of NFE2L2 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 protein] lycopene promotes the reaction [Atrazine results in increased expression of NFE2L2 mRNA] |
CTD |
PMID:19551842 PMID:27102619 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 More...
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in increased expression of NFKB1 mRNA] |
CTD |
PMID:27102619 |
|
NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
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G |
NFKBIA |
NFKB inhibitor alpha |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; Lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA] |
CTD |
PMID:25551565 |
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NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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G |
NLRP3 |
NLR family pyrin domain containing 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 protein] |
CTD |
PMID:36610486 |
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NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108
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G |
NOS1 |
nitric oxide synthase 1 |
decreases expression |
EXP |
lycopene results in decreased expression of NOS1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
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G |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of NQO1 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of NQO1 mRNA] |
CTD |
PMID:28974442 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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G |
NR1H3 |
nuclear receptor subfamily 1 group H member 3 |
increases expression |
EXP |
Lycopene increases expression of NR1H3 protein in macrophages |
RGD |
PMID:21208793 |
RGD:401842374 |
NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
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NR1I2 |
nuclear receptor subfamily 1 group I member 2 |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of NR1I2 mRNA; Lycopene results in increased expression of NR1I2 protein Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 protein] |
CTD |
PMID:36216167 PMID:36403809 |
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NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
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NR1I3 |
nuclear receptor subfamily 1 group I member 3 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 protein] Lycopene results in increased expression of NR1I3 mRNA |
CTD |
PMID:36216167 PMID:36403809 |
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NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
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NR3C2 |
nuclear receptor subfamily 3 group C member 2 |
multiple interactions |
ISO |
[Lycopene co-treated with Atrazine] results in increased expression of NR3C2 mRNA |
CTD |
PMID:36216167 |
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NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698
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NTRK2 |
neurotrophic receptor tyrosine kinase 2 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [bisphenol A results in decreased expression of NTRK2 protein] Lycopene results in increased expression of NTRK2 protein |
CTD |
PMID:32153214 |
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NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751
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NUP214 |
nucleoporin 214 |
decreases expression |
EXP |
lycopene results in decreased expression of NUP214 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 9:131,125,586...131,234,663
Ensembl chr 9:131,125,573...131,234,663
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NUP62 |
nucleoporin 62 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NUP62 mRNA] |
CTD |
PMID:35917956 |
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NCBI chr19:49,906,825...49,929,504
Ensembl chr19:49,906,825...49,929,764
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PAH |
phenylalanine hydroxylase |
decreases expression |
ISO |
lycopene results in decreased expression of PAH mRNA |
CTD |
PMID:19555370 |
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NCBI chr12:102,836,889...102,958,441
Ensembl chr12:102,836,889...102,958,410
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PARP1 |
poly(ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [decamethrin results in increased activity of PARP1 protein] |
CTD |
PMID:23076637 |
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NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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PCNA |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
lycopene inhibits the reaction [[Diethylnitrosamine co-treated with Dietary Fats] results in increased expression of PCNA protein] |
CTD |
PMID:19551842 |
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NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
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G |
PINK1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 protein] |
CTD |
PMID:36583613 |
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NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
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PLA2G2A |
phospholipase A2 group IIA |
multiple interactions |
EXP |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein] |
CTD |
PMID:22429818 |
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NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
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POMC |
proopiomelanocortin |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in increased secretion of POMC protein modified form] |
CTD |
PMID:27102619 |
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NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
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PPARA |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine affects the expression of PPARA mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of PPARA protein] |
CTD |
PMID:36216167 |
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NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions increases expression |
ISO |
[Lycopene co-treated with Atrazine] results in increased expression of PPARG mRNA Lycopene results in increased expression of PPARG mRNA |
CTD |
PMID:36216167 |
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NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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PRDX1 |
peroxiredoxin 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX1 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
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PRDX2 |
peroxiredoxin 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX2 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
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G |
PRKAA2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
increases expression increases phosphorylation multiple interactions |
ISO |
Lycopene results in increased expression of PRKAA2 mRNA Lycopene results in increased phosphorylation of PRKAA2 protein Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAA2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased phosphorylation of PRKAA2 protein] |
CTD |
PMID:30360616 |
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NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335
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G |
PRKAB1 |
protein kinase AMP-activated non-catalytic subunit beta 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAB1 mRNA] |
CTD |
PMID:30360616 |
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NCBI chr12:119,667,952...119,681,619
Ensembl chr12:119,667,864...119,681,624
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G |
PRKAB2 |
protein kinase AMP-activated non-catalytic subunit beta 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of PRKAB2 mRNA] |
CTD |
PMID:30360616 |
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NCBI chr 1:147,155,106...147,172,470
Ensembl chr 1:147,155,106...147,172,550
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G |
PRKAG2 |
protein kinase AMP-activated non-catalytic subunit gamma 2 |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine results in increased expression of PRKAG2 mRNA] |
CTD |
PMID:30360616 |
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NCBI chr 7:151,556,127...151,877,115
Ensembl chr 7:151,556,124...151,877,214
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PRKDC |
protein kinase, DNA-activated, catalytic subunit |
decreases expression |
EXP |
lycopene results in decreased expression of PRKDC mRNA |
CTD |
PMID:16886892 |
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NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178
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G |
PRKN |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN protein] |
CTD |
PMID:36583613 |
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NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
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PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of PTGS2 mRNA]; Lycopene inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA] |
CTD |
PMID:28974442 PMID:36216167 |
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
PYCARD |
PYD and CARD domain containing |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD protein] |
CTD |
PMID:36610486 |
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NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450
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G |
RAD50 |
RAD50 double strand break repair protein |
increases expression |
EXP |
lycopene results in increased expression of RAD50 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349
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G |
RASSF7 |
Ras association domain family member 7 |
increases expression |
EXP |
lycopene results in increased expression of RASSF7 mRNA |
CTD |
PMID:16886892 |
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NCBI chr11:560,970...564,025
Ensembl chr11:560,404...564,025
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G |
RB1 |
RB transcriptional corepressor 1 |
multiple interactions decreases phosphorylation |
EXP |
lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] lycopene results in decreased phosphorylation of RB1 protein |
CTD |
PMID:16565789 PMID:17051425 PMID:17337101 |
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NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
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G |
RDX |
radixin |
decreases expression |
EXP |
lycopene results in decreased expression of RDX mRNA |
CTD |
PMID:16886892 |
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NCBI chr11:110,174,922...110,296,614
Ensembl chr11:109,864,295...110,296,712
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G |
RELA |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of RELA protein] |
CTD |
PMID:36583613 |
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NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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G |
RPS6KA1 |
ribosomal protein S6 kinase A1 |
decreases expression |
EXP |
lycopene results in decreased expression of RPS6KA1 protein |
CTD |
PMID:17337101 |
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NCBI chr 1:26,529,761...26,575,025
Ensembl chr 1:26,529,761...26,575,030
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G |
RPS6KA3 |
ribosomal protein S6 kinase A3 |
decreases expression |
EXP |
lycopene results in decreased expression of RPS6KA3 protein |
CTD |
PMID:17337101 |
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NCBI chr X:20,149,911...20,267,097
Ensembl chr X:20,149,911...20,267,519
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RRM2 |
ribonucleotide reductase regulatory subunit M2 |
increases expression |
EXP |
lycopene results in increased expression of RRM2 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725
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G |
SCGB1D2 |
secretoglobin family 1D member 2 |
decreases expression |
ISO |
lycopene results in decreased expression of SCGB1D2 mRNA |
CTD |
PMID:15084515 |
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NCBI chr11:62,242,239...62,244,812
Ensembl chr11:62,242,239...62,244,812
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G |
SCGB1D4 |
secretoglobin family 1D member 4 |
decreases expression |
ISO |
lycopene results in decreased expression of SCGB1D4 mRNA |
CTD |
PMID:15084515 |
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NCBI chr11:62,296,281...62,299,075
Ensembl chr11:62,296,281...62,299,075
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G |
SELE |
selectin E |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA] |
CTD |
PMID:22429818 PMID:25551565 |
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NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
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SELENOP |
selenoprotein P |
decreases expression |
EXP |
lycopene results in decreased expression of SELENOP mRNA |
CTD |
PMID:16886892 |
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NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392
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G |
SIRT1 |
sirtuin 1 |
multiple interactions |
EXP |
lycopene inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein] |
CTD |
PMID:28974442 |
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NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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G |
SKAP2 |
src kinase associated phosphoprotein 2 |
decreases expression |
ISO |
lycopene results in decreased expression of SKAP2 mRNA |
CTD |
PMID:19555370 |
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NCBI chr 7:26,654,770...26,864,590
Ensembl chr 7:26,667,068...26,995,239
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G |
SMAD3 |
SMAD family member 3 |
increases expression |
EXP |
lycopene results in increased expression of SMAD3 mRNA |
CTD |
PMID:16886892 |
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NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
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G |
SMC1A |
structural maintenance of chromosomes 1A |
decreases expression |
EXP |
lycopene results in decreased expression of SMC1A mRNA |
CTD |
PMID:16886892 |
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NCBI chr X:53,374,149...53,422,728
Ensembl chr X:53,374,149...53,422,728
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD1 mRNA]; Lycopene promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SOD1 protein] Lycopene results in increased expression of SOD1 mRNA |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 protein] |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SOD3 |
superoxide dismutase 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD3 mRNA] |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
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G |
SQSTM1 |
sequestosome 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA alternative form]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 protein] |
CTD |
PMID:30360616 PMID:36583613 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SRD5A1 |
steroid 5 alpha-reductase 1 |
decreases expression |
ISO |
lycopene results in decreased expression of SRD5A1 mRNA |
CTD |
PMID:15084515 |
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NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539
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G |
STAR |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of STAR protein]; lycopene inhibits the reaction [decamethrin results in decreased expression of STAR mRNA] |
CTD |
PMID:19071209 PMID:23076637 |
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NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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G |
STAT3 |
signal transducer and activator of transcription 3 |
increases expression |
EXP |
lycopene results in increased expression of STAT3 mRNA |
CTD |
PMID:16886892 |
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NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
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G |
STING1 |
stimulator of interferon response cGAMP interactor 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 protein] |
CTD |
PMID:36583613 |
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NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935
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G |
TBK1 |
TANK binding kinase 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of TBK1 protein] |
CTD |
PMID:36583613 |
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NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114
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G |
TFF1 |
trefoil factor 1 |
decreases expression |
EXP |
lycopene results in decreased expression of TFF1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
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G |
TFPI2 |
tissue factor pathway inhibitor 2 |
decreases expression |
EXP |
lycopene results in decreased expression of TFPI2 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753
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G |
TGFA |
transforming growth factor alpha |
increases expression |
EXP |
lycopene results in increased expression of TGFA mRNA |
CTD |
PMID:16886892 |
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NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
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G |
TLR2 |
toll like receptor 2 |
multiple interactions |
EXP |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] |
CTD |
PMID:22429818 |
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NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260
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G |
TLR4 |
toll like receptor 4 |
multiple interactions |
EXP ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] Lycopene affects the reaction [Atrazine affects the expression of TLR4 mRNA] |
CTD |
PMID:22429818 PMID:36216167 |
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NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
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G |
TNF |
tumor necrosis factor |
multiple interactions |
ISO EXP |
[Lycopene co-treated with Diethylnitrosamine] results in increased expression of TNF mRNA; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of TNF protein] Lycopene inhibits the reaction [Atrazine results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TNF protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF protein]; Lycopene inhibits the reaction [Galactose results in increased expression of TNF protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of TNF] [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; Lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; Lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; Lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; Lycopene inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; Lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; Lycopene inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; Lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein] |
CTD |
PMID:19551842 PMID:22429818 PMID:25551565 PMID:25682699 PMID:28974442 PMID:32544411 PMID:36216167 PMID:36583613 More...
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TP53 |
tumor protein p53 |
decreases expression multiple interactions |
EXP ISO |
lycopene results in decreased expression of TP53 mRNA Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TP53 mRNA] |
CTD |
PMID:16886892 PMID:36583613 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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G |
TRAF6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 protein] |
CTD |
PMID:36216167 |
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NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272
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G |
TSHB |
thyroid stimulating hormone subunit beta |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of TSHB protein] |
CTD |
PMID:33592256 |
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NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302
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G |
TXN |
thioredoxin |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine affects the expression of TXN1 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
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G |
TXN2 |
thioredoxin 2 |
multiple interactions decreases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of TXN2 mRNA] Lycopene results in decreased expression of TXN2 mRNA |
CTD |
PMID:36216167 |
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NCBI chr22:36,467,046...36,481,640
Ensembl chr22:36,467,046...36,481,640
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G |
VCAM1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:22429818 |
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NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
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G |
VCP |
valosin containing protein |
increases expression |
EXP |
lycopene results in increased expression of VCP mRNA |
CTD |
PMID:16886892 |
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NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668
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G |
VEGFA |
vascular endothelial growth factor A |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of VEGFA protein] |
CTD |
PMID:33592256 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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G |
XBP1 |
X-box binding protein 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 protein] |
CTD |
PMID:36583613 |
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NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
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G |
ZNF138 |
zinc finger protein 138 |
increases expression |
EXP |
lycopene results in increased expression of ZNF138 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 7:64,794,428...64,860,823
Ensembl chr 7:64,794,388...64,833,681
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