BRAF (B-Raf proto-oncogene, serine/threonine kinase) - Rat Genome Database

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Gene: BRAF (B-Raf proto-oncogene, serine/threonine kinase) Homo sapiens
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Symbol: BRAF
Name: B-Raf proto-oncogene, serine/threonine kinase
RGD ID: 735645
HGNC Page HGNC:1097
Description: Enables several functions, including identical protein binding activity; protein kinase activity; and scaffold protein binding activity. Involved in several processes, including positive regulation of D-glucose transmembrane transport; positive regulation of ERK1 and ERK2 cascade; and positive regulation of macromolecule metabolic process. Located in cytosol and intracellular membrane-bounded organelle. Implicated in several diseases, including Noonan syndrome 7; carcinoma (multiple); cardiofaciocutaneous syndrome (multiple); central nervous system benign neoplasm (multiple); and melanoma (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 94 kDa B-raf protein; B-raf; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf serine/threonine-protein; B-RAF1; BRAF-1; BRAF1; FLJ95109; MGC126806; MGC138284; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; proto-oncogene B-Raf; RAFB1; serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: BRAFP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387140,713,328 - 140,924,929 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7140,719,327 - 140,924,929 (-)EnsemblGRCh38hg38GRCh38
GRCh377140,413,128 - 140,624,729 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367140,080,751 - 140,271,033 (-)NCBINCBI36Build 36hg18NCBI36
Build 347139,887,462 - 140,077,748NCBI
Celera7135,155,867 - 135,346,614 (-)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7134,729,459 - 134,920,529 (-)NCBIHuRef
CHM1_17140,368,045 - 140,559,148 (-)NCBICHM1_1
T2T-CHM13v2.07142,027,505 - 142,239,131 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27139,771,989 - 139,962,886 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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