AQP11 (aquaporin 11) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: AQP11 (aquaporin 11) Homo sapiens
Analyze
Symbol: AQP11
Name: aquaporin 11
RGD ID: 736750
HGNC Page HGNC:19940
Description: Enables glycerol channel activity and water channel activity. Involved in several processes, including glycerol transmembrane transport; hydrogen peroxide transmembrane transport; and intracellular water homeostasis. Located in cell surface; endoplasmic reticulum; and plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AQP-11; AQPX1; aquaporin-11
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381177,589,953 - 77,610,356 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1177,589,391 - 77,610,356 (+)EnsemblGRCh38hg38GRCh38
GRCh371177,300,998 - 77,321,401 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,978,328 - 76,998,342 (+)NCBINCBI36Build 36hg18NCBI36
Build 341176,978,327 - 76,998,339NCBI
Celera1174,608,361 - 74,629,072 (+)NCBICelera
Cytogenetic Map11q14.1NCBI
HuRef1173,599,078 - 73,619,798 (+)NCBIHuRef
CHM1_11177,183,785 - 77,204,503 (+)NCBICHM1_1
T2T-CHM13v2.01177,523,008 - 77,543,410 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1373524   PMID:1510932   PMID:7530250   PMID:9369468   PMID:9405233   PMID:9806845   PMID:9829975   PMID:10510269   PMID:10564231   PMID:11001937   PMID:11034202   PMID:11076974  
PMID:11573934   PMID:12084581   PMID:12477932   PMID:14701836   PMID:15489334   PMID:15948717   PMID:16107722   PMID:16303743   PMID:16596446   PMID:16650285   PMID:17178220   PMID:17207965  
PMID:18202181   PMID:18501347   PMID:18511455   PMID:18762715   PMID:21118806   PMID:21251984   PMID:21873635   PMID:21988832   PMID:23359558   PMID:23643386   PMID:24845055   PMID:24918044  
PMID:26719361   PMID:28042826   PMID:30010847   PMID:30563120   PMID:31046802   PMID:31546170   PMID:31685402   PMID:32512939   PMID:36403720   PMID:36420936   PMID:38451099  


Genomics

Comparative Map Data
AQP11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381177,589,953 - 77,610,356 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1177,589,391 - 77,610,356 (+)EnsemblGRCh38hg38GRCh38
GRCh371177,300,998 - 77,321,401 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,978,328 - 76,998,342 (+)NCBINCBI36Build 36hg18NCBI36
Build 341176,978,327 - 76,998,339NCBI
Celera1174,608,361 - 74,629,072 (+)NCBICelera
Cytogenetic Map11q14.1NCBI
HuRef1173,599,078 - 73,619,798 (+)NCBIHuRef
CHM1_11177,183,785 - 77,204,503 (+)NCBICHM1_1
T2T-CHM13v2.01177,523,008 - 77,543,410 (+)NCBIT2T-CHM13v2.0
Aqp11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39797,375,586 - 97,387,454 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl797,373,213 - 97,387,496 (-)EnsemblGRCm39 Ensembl
GRCm38797,726,379 - 97,738,247 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl797,724,006 - 97,738,289 (-)EnsemblGRCm38mm10GRCm38
MGSCv377104,874,889 - 104,886,757 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36797,601,571 - 97,613,439 (-)NCBIMGSCv36mm8
Celera798,046,312 - 98,058,532 (-)NCBICelera
Cytogenetic Map7E1NCBI
cM Map753.57NCBI
Aqp11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81161,457,752 - 161,467,918 (-)NCBIGRCr8
mRatBN7.21152,046,515 - 152,056,675 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1152,046,517 - 152,056,725 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1160,033,373 - 160,043,515 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,213,553 - 167,223,696 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01160,087,040 - 160,097,182 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01162,703,394 - 162,713,560 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1162,703,442 - 162,713,610 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01168,910,171 - 168,920,337 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41154,973,796 - 154,983,962 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11155,052,203 - 155,062,368 (-)NCBI
Celera1150,140,146 - 150,150,299 (-)NCBICelera
Cytogenetic Map1q32NCBI
Aqp11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541414,245,682 - 14,260,717 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541414,245,682 - 14,260,717 (-)NCBIChiLan1.0ChiLan1.0
AQP11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2978,522,280 - 78,547,456 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,570,672 - 79,595,844 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01172,653,721 - 72,673,698 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11176,295,778 - 76,315,292 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1176,295,778 - 76,315,292 (+)Ensemblpanpan1.1panPan2
AQP11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12121,170,760 - 21,185,709 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2121,171,008 - 21,185,429 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2121,062,597 - 21,077,580 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02121,368,876 - 21,383,901 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2121,367,271 - 21,383,947 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12121,145,467 - 21,160,437 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02121,361,689 - 21,376,239 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02121,285,087 - 21,299,649 (-)NCBIUU_Cfam_GSD_1.0
Aqp11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494764,613,980 - 64,634,881 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364986,213,583 - 6,237,273 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AQP11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl912,065,546 - 12,078,401 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1912,065,550 - 12,076,339 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2913,217,315 - 13,228,258 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AQP11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1168,805,354 - 68,824,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl168,807,025 - 68,824,792 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604356,947,167 - 56,965,056 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aqp11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624863678,953 - 694,505 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624863679,049 - 694,765 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AQP11
16 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q13.4-14.1(chr11:71923251-79662025)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052684]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052684]|See cases [RCV000052684] Chr11:71923251..79662025 [GRCh38]
Chr11:71634297..79373069 [GRCh37]
Chr11:71311945..79050717 [NCBI36]
Chr11:11q13.4-14.1		 pathogenic
GRCh38/hg38 11q13.4-14.1(chr11:71969881-78232895)x1 copy number loss See cases [RCV000052709] Chr11:71969881..78232895 [GRCh38]
Chr11:71680927..77943941 [GRCh37]
Chr11:71358575..77621589 [NCBI36]
Chr11:11q13.4-14.1		 pathogenic
GRCh38/hg38 11q13.5-22.1(chr11:75941754-98357960)x1 copy number loss See cases [RCV000133838] Chr11:75941754..98357960 [GRCh38]
Chr11:75652798..98228688 [GRCh37]
Chr11:75330446..97733898 [NCBI36]
Chr11:11q13.5-22.1		 pathogenic
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_173039.3(AQP11):c.472C>G (p.Pro158Ala) single nucleotide variant Inborn genetic diseases [RCV003281278] Chr11:77590464 [GRCh38]
Chr11:77301509 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.262G>T (p.Val88Leu) single nucleotide variant Inborn genetic diseases [RCV003293091] Chr11:77590254 [GRCh38]
Chr11:77301299 [GRCh37]
Chr11:11q14.1		 uncertain significance
GRCh37/hg19 11q13.5-14.1(chr11:76895239-77568340)x3 copy number gain not provided [RCV000683346] Chr11:76895239..77568340 [GRCh37]
Chr11:11q13.5-14.1		 uncertain significance
GRCh37/hg19 11q13.4-23.3(chr11:71588805-116680918)x3 copy number gain not provided [RCV000683374] Chr11:71588805..116680918 [GRCh37]
Chr11:11q13.4-23.3		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q14.1(chr11:77276494-77430704)x3 copy number gain not provided [RCV000849449] Chr11:77276494..77430704 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.456C>A (p.Ser152Arg) single nucleotide variant Inborn genetic diseases [RCV003247481] Chr11:77590448 [GRCh38]
Chr11:77301493 [GRCh37]
Chr11:11q14.1		 uncertain significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
NM_173039.3(AQP11):c.780G>T (p.Trp260Cys) single nucleotide variant not provided [RCV001728136] Chr11:77609341 [GRCh38]
Chr11:77320386 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.472C>T (p.Pro158Ser) single nucleotide variant not provided [RCV001728137] Chr11:77590464 [GRCh38]
Chr11:77301509 [GRCh37]
Chr11:11q14.1		 uncertain significance
GRCh37/hg19 11q14.1(chr11:77211136-78014355)x3 copy number gain not provided [RCV002474594] Chr11:77211136..78014355 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.23G>C (p.Arg8Pro) single nucleotide variant Inborn genetic diseases [RCV002707249] Chr11:77590015 [GRCh38]
Chr11:77301060 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.299C>T (p.Pro100Leu) single nucleotide variant Inborn genetic diseases [RCV002660012] Chr11:77590291 [GRCh38]
Chr11:77301336 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.613T>C (p.Tyr205His) single nucleotide variant Inborn genetic diseases [RCV002797470] Chr11:77590605 [GRCh38]
Chr11:77301650 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.22C>G (p.Arg8Gly) single nucleotide variant Inborn genetic diseases [RCV002980470] Chr11:77590014 [GRCh38]
Chr11:77301059 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.121A>G (p.Arg41Gly) single nucleotide variant Inborn genetic diseases [RCV002809293] Chr11:77590113 [GRCh38]
Chr11:77301158 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.556G>A (p.Glu186Lys) single nucleotide variant Inborn genetic diseases [RCV002936205] Chr11:77590548 [GRCh38]
Chr11:77301593 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.63G>T (p.Met21Ile) single nucleotide variant Inborn genetic diseases [RCV003259737] Chr11:77590055 [GRCh38]
Chr11:77301100 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.434A>C (p.Gln145Pro) single nucleotide variant not provided [RCV003395939] Chr11:77590426 [GRCh38]
Chr11:77301471 [GRCh37]
Chr11:11q14.1		 likely benign
NM_173039.3(AQP11):c.538G>A (p.Ala180Thr) single nucleotide variant Inborn genetic diseases [RCV003352743] Chr11:77590530 [GRCh38]
Chr11:77301575 [GRCh37]
Chr11:11q14.1		 uncertain significance
NM_173039.3(AQP11):c.435G>T (p.Gln145His) single nucleotide variant not provided [RCV003395940] Chr11:77590427 [GRCh38]
Chr11:77301472 [GRCh37]
Chr11:11q14.1		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:437
Count of miRNA genes:340
Interacting mature miRNAs:367
Transcripts:ENST00000313578, ENST00000528638
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH92330  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371177,319,940 - 77,320,088UniSTSGRCh37
Build 361176,997,588 - 76,997,736RGDNCBI36
Celera1174,627,611 - 74,627,759RGD
Cytogenetic Map11q14.1UniSTS
HuRef1173,618,337 - 73,618,485UniSTS
GeneMap99-GB4 RH Map11278.1UniSTS
RH123239  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371177,320,225 - 77,320,504UniSTSGRCh37
Build 361176,997,873 - 76,998,152RGDNCBI36
Celera1174,627,896 - 74,628,175RGD
Cytogenetic Map11q14.1UniSTS
HuRef1173,618,622 - 73,618,901UniSTS
TNG Radiation Hybrid Map1135287.0UniSTS
TNG Radiation Hybrid Map1135275.0UniSTS
G62578  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371177,313,450 - 77,313,777UniSTSGRCh37
Build 361176,991,098 - 76,991,425RGDNCBI36
Celera1174,621,122 - 74,621,449RGD
Cytogenetic Map11q14.1UniSTS
HuRef1173,611,849 - 73,612,176UniSTS
TNG Radiation Hybrid Map1135266.0UniSTS
SHGC-31328  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371177,320,505 - 77,320,654UniSTSGRCh37
Build 361176,998,153 - 76,998,302RGDNCBI36
Celera1174,628,176 - 74,628,325RGD
Cytogenetic Map11q14.1UniSTS
HuRef1173,618,902 - 73,619,051UniSTS
TNG Radiation Hybrid Map1135257.0UniSTS
Stanford-G3 RH Map113414.0UniSTS
NCBI RH Map11637.3UniSTS
GeneMap99-G3 RH Map113414.0UniSTS
SHGC-1207  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371177,317,429 - 77,317,561UniSTSGRCh37
Build 361176,995,077 - 76,995,209RGDNCBI36
Celera1174,625,100 - 74,625,232RGD
Cytogenetic Map11q14.1UniSTS
HuRef1173,615,826 - 73,615,958UniSTS
TNG Radiation Hybrid Map1135283.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 63 321 119 41 119 6 95 16 511 22 2
Low 2353 1976 1398 500 1216 346 3914 1617 3608 392 935 1553 170 1 1171 2378 5
Below cutoff 23 995 7 5 665 436 577 31 10 11 38 4 33 408 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000313578   ⟹   ENSP00000318770
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1177,589,953 - 77,610,356 (+)Ensembl
RefSeq Acc Id: ENST00000528638
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1177,589,391 - 77,610,009 (+)Ensembl
RefSeq Acc Id: NM_001363477   ⟹   NP_001350406
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381177,589,953 - 77,610,356 (+)NCBI
T2T-CHM13v2.01177,523,008 - 77,543,410 (+)NCBI
Sequence:
RefSeq Acc Id: NM_173039   ⟹   NP_766627
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381177,589,953 - 77,610,356 (+)NCBI
GRCh371177,300,680 - 77,321,401 (+)RGD
Build 361176,978,328 - 76,998,342 (+)NCBI Archive
Celera1174,608,361 - 74,629,072 (+)RGD
HuRef1173,599,078 - 73,619,798 (+)ENTREZGENE
CHM1_11177,183,785 - 77,204,503 (+)NCBI
T2T-CHM13v2.01177,523,008 - 77,543,410 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_766627   ⟸   NM_173039
- Peptide Label: isoform 1
- UniProtKB: Q8NBQ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001350406   ⟸   NM_001363477
- Peptide Label: isoform 2
RefSeq Acc Id: ENSP00000318770   ⟸   ENST00000313578

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8NBQ7-F1-model_v2 AlphaFold Q8NBQ7 1-271 view protein structure

Promoters
RGD ID:6788486
Promoter ID:HG_KWN:13794
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid
Transcripts:NM_173039,   UC009YUU.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361176,977,581 - 76,978,817 (+)MPROMDB
RGD ID:7221631
Promoter ID:EPDNEW_H16561
Type:initiation region
Name:AQP11_1
Description:aquaporin 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16562  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381177,589,656 - 77,589,716EPDNEW
RGD ID:7221633
Promoter ID:EPDNEW_H16562
Type:initiation region
Name:AQP11_2
Description:aquaporin 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16561  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381177,589,953 - 77,590,013EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:19940 AgrOrtholog
COSMIC AQP11 COSMIC
Ensembl Genes ENSG00000178301 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000313578 ENTREZGENE
  ENST00000313578.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1080.10 UniProtKB/Swiss-Prot
GTEx ENSG00000178301 GTEx
HGNC ID HGNC:19940 ENTREZGENE
Human Proteome Map AQP11 Human Proteome Map
InterPro Aquaporin-like UniProtKB/Swiss-Prot
  Aquaporin_11 UniProtKB/Swiss-Prot
  Aquaporin_11/12 UniProtKB/Swiss-Prot
  MIP UniProtKB/Swiss-Prot
KEGG Report hsa:282679 UniProtKB/Swiss-Prot
NCBI Gene 282679 ENTREZGENE
OMIM 609914 OMIM
PANTHER AQUAPORIN UniProtKB/Swiss-Prot
  PTHR21191:SF7 UniProtKB/Swiss-Prot
Pfam MIP UniProtKB/Swiss-Prot
PharmGKB PA134949682 PharmGKB
PIRSF Aquaporin_11/12 UniProtKB/Swiss-Prot
PRINTS AQUAPORIN11 UniProtKB/Swiss-Prot
  MINTRINSICP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF81338 UniProtKB/Swiss-Prot
UniProt AQP11_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE