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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | EXP | | 6480464 | [potassium chromateVI co-treated with epigallocatechin gallate] results in decreased expression of ATG4A mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1616955 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of ATG4A mRNA | CTD | PMID:22206623 | 3-methyladenine | decreases expression | ISO | RGD:1616955 | 6480464 | 3-methyladenine results in decreased expression of ATG4A mRNA | CTD | PMID:21681844 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1616955 | 6480464 | Fenretinide results in increased expression of ATG4A mRNA | CTD | PMID:28973697 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of ATG4A mRNA | CTD | PMID:32763439 | aflatoxin B2 | increases methylation | EXP | | 6480464 | aflatoxin B2 results in increased methylation of ATG4A intron | CTD | PMID:30157460 | Aroclor 1254 | decreases expression | ISO | RGD:1616955 | 6480464 | Chlorodiphenyl 54% Chlorine results in decreased expression of ATG4A mRNA | CTD | PMID:23650126 | atrazine | multiple interactions | ISO | RGD:1616955 | 6480464 | Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4A mRNA] | CTD | PMID:30360616 | atrazine | decreases expression | ISO | RGD:1616955 | 6480464 | Atrazine results in decreased expression of ATG4A mRNA | CTD | PMID:30360616 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzoapyrene results in increased methylation of ATG4A exon | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzoapyrene affects the methylation of ATG4A promoter | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | RGD:1596915 | 6480464 | bisphenol A results in increased expression of ATG4A mRNA | CTD | PMID:25181051 | cadmium dichloride | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ATG4A protein] more ... | CTD | PMID:29179951 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of ATG4A protein | CTD | PMID:29179951 | cadmium dichloride | increases expression | ISO | RGD:1616955 | 6480464 | Cadmium Chloride results in increased expression of ATG4A protein | CTD | PMID:29179951 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of ATG4A mRNA | CTD | PMID:30871063 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of ATG4A mRNA | CTD | PMID:19376846 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of ATG4A mRNA | CTD | PMID:25562108 | disodium selenite | increases expression | EXP | | 6480464 | Sodium Selenite results in increased expression of ATG4A mRNA | CTD | PMID:18175754 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of ATG4A mRNA | CTD | PMID:27188386 | isotretinoin | decreases expression | EXP | | 6480464 | Isotretinoin results in decreased expression of ATG4A mRNA | CTD | PMID:20436886 | lycopene | multiple interactions | ISO | RGD:1616955 | 6480464 | Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4A mRNA] | CTD | PMID:30360616 | methotrexate | increases expression | EXP | | 6480464 | Methotrexate results in increased expression of ATG4A mRNA | CTD | PMID:21678067 | methylisothiazolinone | increases expression | EXP | | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of ATG4A mRNA | CTD | PMID:31629900 | N-acetyl-L-cysteine | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ATG4A protein] | CTD | PMID:29179951 | paracetamol | affects expression | ISO | RGD:1616955 | 6480464 | Acetaminophen affects the expression of ATG4A mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ATG4A mRNA | CTD | PMID:29067470 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ATG4A mRNA | CTD | PMID:22230336 | perfluorononanoic acid | decreases expression | EXP | | 6480464 | perfluorononanoic acid results in decreased expression of ATG4A mRNA | CTD | PMID:32588087 | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromateVI results in decreased expression of ATG4A mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | EXP | | 6480464 | [potassium chromateVI co-treated with epigallocatechin gallate] results in decreased expression of ATG4A mRNA | CTD | PMID:22079256 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of ATG4A mRNA | CTD | PMID:27188386 | sirolimus | increases expression | ISO | RGD:1616955 | 6480464 | Sirolimus results in increased expression of ATG4A mRNA | CTD | PMID:21681844 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of ATG4A mRNA | CTD | PMID:31533062 | triptonide | decreases expression | ISO | RGD:1616955 | 6480464 | triptonide results in decreased expression of ATG4A mRNA | CTD | PMID:33045310 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of ATG4A mRNA | CTD | PMID:19140230 | tungsten | increases expression | ISO | RGD:1616955 | 6480464 | Tungsten results in increased expression of ATG4A mRNA | CTD | PMID:30912803 | urethane | increases expression | EXP | | 6480464 | Urethane results in increased expression of ATG4A mRNA | CTD | PMID:28818685 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ATG4A mRNA | CTD | PMID:25979313 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of ATG4A mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of ATG4A mRNA | CTD | PMID:27188386 | vinclozolin | decreases methylation | ISO | RGD:1596915 | 6480464 | vinclozolin results in decreased methylation of ATG4A gene | CTD | PMID:31079544 | vorinostat | increases expression | EXP | | 6480464 | vorinostat results in increased expression of ATG4A mRNA | CTD | PMID:27188386 | |