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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736925
Species: Homo sapiens
RGD Object: Gene
Symbol: GJA1
Name: gap junction protein alpha 1
Acc ID: CHEBI:15948
Term: lycopene
Definition: An acyclic carotene commonly obtained from tomatoes and other red fruits.
Chemical ID: MESH:C015329
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GJA1increases expressionISOGja1 (Mus musculus)6480464CTDlycopene results in increased expression of GJA1 proteinPMID:16091010
GJA1multiple interactionsISOGja1 (Rattus norvegicus)6480464CTDLycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of GJA1 protein]PMID:31568845
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