CRB1 (crumbs cell polarity complex component 1) - Rat Genome Database

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Gene: CRB1 (crumbs cell polarity complex component 1) Homo sapiens
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Symbol: CRB1
Name: crumbs cell polarity complex component 1
RGD ID: 1320564
HGNC Page HGNC:2343
Description: Predicted to enable calcium ion binding activity. Predicted to be involved in establishment or maintenance of epithelial cell apical/basal polarity and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to act upstream of with a positive effect on gene expression. Predicted to act upstream of with a negative effect on protein localization. Predicted to act upstream of or within several processes, including detection of light stimulus involved in visual perception; eye morphogenesis; and neurogenesis. Located in adherens junction. Part of protein-containing complex. Implicated in pigmented paravenous chorioretinal atrophy and retinal disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CRB1-A; CRB1-B; CRB1-C; crumbs 1, cell polarity complex component; crumbs family member 1, photoreceptor morphogenesis associated; crumbs homolog 1; LCA8; RP12
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381197,201,504 - 197,478,455 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1197,268,204 - 197,478,455 (+)EnsemblGRCh38hg38GRCh38
GRCh371197,170,634 - 197,447,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361195,504,031 - 195,714,208 (+)NCBINCBI36Build 36hg18NCBI36
Build 341193,969,064 - 194,179,241NCBI
Celera1170,362,823 - 170,573,037 (+)NCBICelera
Cytogenetic Map1q31.3NCBI
HuRef1168,328,124 - 168,606,472 (+)NCBIHuRef
CHM1_11198,593,055 - 198,870,040 (+)NCBICHM1_1
T2T-CHM13v2.01196,463,303 - 196,740,260 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model