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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hydroquinone
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Accession:CHEBI:17594 term browser browse the term
Definition:A benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
Synonyms:related_synonym: 1,4-Benzenediol;   1,4-Dihydroxybenzene;   4-Hydroxyphenol;   Benzene-1,4-diol;   Eldoquin;   Formula=C6H6O2;   InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H;   InChIKey=QIGBRXMKCJKVMJ-UHFFFAOYSA-N;   Quinol;   SMILES=Oc1ccc(O)cc1;   p-Benzenediol;   p-Hydroquinone;   p-hydroxyphenol
 alt_id: CHEBI:14416;   CHEBI:24645;   CHEBI:5793
 xref: Beilstein:605970;   CAS:123-31-9;   Drug_Central:3282;   Gmelin:2742;   HMDB:HMDB0002434;   KEGG:C00530;   KEGG:C15603;   KEGG:D00073;   KNApSAcK:C00002656
 xref_mesh: MESH:C031927
 xref: MetaCyc:HYDROQUINONE;   PMID:11170505;   PMID:12213471;   PMID:1395635;   PMID:15618234;   PMID:15894107;   PMID:1899343;   PMID:19148301;   PMID:24407054;   PMID:24858384;   PMID:25586344;   PPDB:1503;   Reaxys:605970;   UM-BBD_compID:c0091;   Wikipedia:Hydroquinone


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hydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase decreases expression ISO hydroquinone results in decreased expression of A4GALT mRNA CTD PMID:31256213 NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071 		JBrowse link
G Aatf apoptosis antagonizing transcription factor multiple interactions
increases expression
increases ADP-ribosylation		 ISO PARP1 protein affects the reaction [hydroquinone results in increased expression of AATF protein]
hydroquinone results in increased ADP-ribosylation of AATF protein		 CTD PMID:26822515 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO hydroquinone results in increased expression of ABCC3 mRNA CTD PMID:31256213 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO hydroquinone results in decreased expression of ACE2 mRNA CTD PMID:31256213 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of ADAM17 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of ADAM17 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]; ADAM17 protein affects the reaction [hydroquinone results in increased secretion of TNF protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased expression of ADAM17 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]		 CTD PMID:23791922 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adap2 ArfGAP with dual PH domains 2 increases expression ISO hydroquinone results in increased expression of ADAP2 mRNA CTD PMID:31256213 NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 multiple interactions ISO hydroquinone inhibits the reaction [Estradiol results in increased expression of ADARB2 mRNA] CTD PMID:28704378 NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831 		JBrowse link
G Adprh ADP-ribosylarginine hydrolase increases expression ISO hydroquinone results in increased expression of ADPRH mRNA CTD PMID:31256213 NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931 		JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein increases expression ISO hydroquinone results in increased expression of ADTRP mRNA CTD PMID:31256213 NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826 		JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO hydroquinone results in increased expression of AEN mRNA CTD PMID:23416264 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Afap1 actin filament associated protein 1 decreases expression ISO hydroquinone results in decreased expression of AFAP1 mRNA CTD PMID:31256213 NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263 		JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 decreases expression ISO hydroquinone results in decreased expression of AGGF1 mRNA CTD PMID:31256213 NCBI chr 2:26,619,336...26,646,050
Ensembl chr 2:26,619,339...26,645,952 		JBrowse link
G Ahr aryl hydrocarbon receptor affects localization
multiple interactions
increases expression		 ISO
EXP		 hydroquinone affects the localization of AHR protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and affects the localization of AHR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of AHR protein]; hydroquinone results in increased expression of and affects the localization of AHR protein
alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein]		 CTD PMID:15935814 PMID:29935983 PMID:35123993 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 increases expression ISO hydroquinone results in increased expression of AIFM2 mRNA CTD PMID:31256213 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression ISO hydroquinone results in decreased expression of AKR1B10 mRNA CTD PMID:31256213 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 ISO hydroquinone inhibits the reaction [AKT1 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of AKT1 protein]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein]
4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]		 CTD PMID:17464197 PMID:28883758 PMID:37148176 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions ISO hydroquinone inhibits the reaction [AKT2 protein results in increased phosphorylation of IRF3 protein] CTD PMID:28883758 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 multiple interactions ISO hydroquinone inhibits the reaction [AKT3 protein results in increased phosphorylation of IRF3 protein] CTD PMID:28883758 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of hydroquinone CTD PMID:8831264 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression ISO hydroquinone results in increased expression of ALDH1L2 mRNA CTD PMID:31256213 NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression ISO hydroquinone results in increased expression of ALDH2 mRNA CTD PMID:15452088 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO hydroquinone results in increased expression of ALDH3A1 mRNA CTD PMID:31256213 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type increases expression ISO hydroquinone results in increased expression of ALOX12 mRNA CTD PMID:31256213 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression ISO hydroquinone results in increased expression of ALOX12B mRNA CTD PMID:31256213 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 increases expression ISO hydroquinone results in increased expression of ALOXE3 mRNA CTD PMID:31256213 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328 		JBrowse link
G Alpk1 alpha-kinase 1 increases expression ISO hydroquinone results in increased expression of ALPK1 mRNA CTD PMID:31256213 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression ISO hydroquinone results in increased expression of AMBP mRNA CTD PMID:29221148 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331 		JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A decreases expression ISO hydroquinone results in decreased expression of ANKDD1A mRNA CTD PMID:31256213 NCBI chr 8:66,017,571...66,043,738
Ensembl chr 8:66,017,773...66,042,651 		JBrowse link
G Anxa1 annexin A1 increases expression ISO hydroquinone results in increased expression of ANXA1 mRNA CTD PMID:31256213 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa3 annexin A3 increases expression ISO hydroquinone results in increased expression of ANXA3 mRNA CTD PMID:31256213 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Apoe apolipoprotein E decreases expression
multiple interactions		 EXP hydroquinone results in decreased expression of APOE mRNA
[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of APOE mRNA]		 CTD PMID:33188856 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of APP mRNA CTD PMID:37245849 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO hydroquinone results in decreased expression of AQP3 mRNA CTD PMID:31256213 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Arg1 arginase 1 increases expression ISO hydroquinone results in increased expression of ARG1 mRNA CTD PMID:31256213 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arg2 arginase 2 increases expression ISO hydroquinone results in increased expression of ARG2 mRNA CTD PMID:31256213 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Arhgap27 Rho GTPase activating protein 27 increases expression ISO hydroquinone results in increased expression of ARHGAP27 mRNA CTD PMID:31256213 NCBI chr10:88,280,470...88,313,225
Ensembl chr10:88,280,455...88,313,185 		JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases expression ISO hydroquinone results in decreased expression of ARHGAP42 mRNA CTD PMID:31256213 NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha affects expression ISO hydroquinone affects the expression of ARHGDIA protein CTD PMID:17181942 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO hydroquinone results in increased expression of ARHGEF2 mRNA CTD PMID:31256213 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 decreases expression ISO hydroquinone results in decreased expression of ARHGEF26 mRNA CTD PMID:31256213 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819 		JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 decreases expression ISO hydroquinone results in decreased expression of ARL3 mRNA CTD PMID:31256213 NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression
multiple interactions		 ISO hydroquinone results in increased expression of ARNT protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ARNT protein]		 CTD PMID:35123993 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO hydroquinone results in increased expression of ASNS mRNA CTD PMID:31256213 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 increases expression ISO hydroquinone results in increased expression of ASPRV1 mRNA CTD PMID:31256213 NCBI chr 4:119,077,415...119,078,887
Ensembl chr 4:119,077,356...119,078,379 		JBrowse link
G Atf2 activating transcription factor 2 increases phosphorylation
multiple interactions		 ISO hydroquinone results in increased phosphorylation of ATF2 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein]; ATF2 protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone promotes the reaction [ATF2 protein binds to MIR122 promoter]; hydroquinone promotes the reaction [ATF2 protein binds to PPP2CA promoter]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein]		 CTD PMID:23288922 PMID:23791922 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO hydroquinone results in increased expression of ATF3 mRNA CTD PMID:31256213 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO hydroquinone results in increased expression of ATF4 mRNA; hydroquinone results in increased expression of ATF4 protein CTD PMID:15452088 PMID:24053669 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
decreases expression
increases expression		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ATF6 protein]; [Sirolimus co-treated with hydroquinone] results in decreased expression of ATF6 protein; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; ATF6 protein affects the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; ATF6 protein affects the reaction [hydroquinone results in increased expression of BAX protein]; ATF6 protein affects the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]
hydroquinone results in decreased expression of ATF6 mRNA; hydroquinone results in decreased expression of ATF6 protein		 CTD PMID:36646296 PMID:37148176 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atg12 autophagy related 12 increases expression ISO hydroquinone results in increased expression of ATG12 protein CTD PMID:37148176 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression		 ISO PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA] CTD PMID:28263894 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Atg7 autophagy related 7 increases expression ISO hydroquinone results in increased expression of ATG7 protein CTD PMID:35302183 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 increases expression ISO hydroquinone results in increased expression of ATP2C2 mRNA CTD PMID:31256213 NCBI chr19:47,754,120...47,811,369
Ensembl chr19:47,754,120...47,811,368 		JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 increases expression ISO hydroquinone results in increased expression of ATP6V1C2 mRNA CTD PMID:31256213 NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding increases expression ISO hydroquinone results in increased expression of AZGP1 mRNA CTD PMID:31256213 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions
decreases expression
affects localization		 ISO [ferric chloride results in increased oxidation of hydroquinone] promotes the reaction [hydroquinone analog binds to BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]
hydroquinone results in decreased expression of BACH1 protein
hydroquinone affects the localization of BACH1 protein		 CTD PMID:23290930 PMID:28645578 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447 		JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO hydroquinone results in decreased expression of BAD mRNA CTD PMID:15452088 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO hydroquinone results in decreased expression of BAG1 mRNA CTD PMID:31256213 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO hydroquinone results in increased expression of BAMBI mRNA CTD PMID:31256213 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
multiple interactions		 ISO hydroquinone results in decreased expression of BAX protein
hydroquinone results in increased expression of BAX protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of BAX protein]; [ABT-737 co-treated with hydroquinone] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; ATF6 protein affects the reaction [hydroquinone results in increased expression of BAX protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of BAX protein]; Sirolimus promotes the reaction [hydroquinone results in increased expression of BAX protein]		 CTD PMID:27515134 PMID:27606422 PMID:28843007 PMID:33771647 PMID:33932074 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO hydroquinone results in increased expression of BBC3 mRNA CTD PMID:23416264 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl11a BCL11 transcription factor A decreases expression ISO hydroquinone results in decreased expression of BCL11A mRNA CTD PMID:31256213 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180 		JBrowse link
G Bcl11b BCL11 transcription factor B decreases expression ISO hydroquinone results in decreased expression of BCL11B mRNA CTD PMID:31256213 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression		 ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein co-treated with hydroquinone] results in increased expression of BCL2 protein; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 protein]
hydroquinone results in decreased expression of BCL2 mRNA; hydroquinone results in decreased expression of BCL2 protein
hydroquinone promotes the reaction [XBP1 protein affects the expression of BCL2 mRNA]; XBP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 mRNA]
hydroquinone results in increased expression of BCL2 mRNA; hydroquinone results in increased expression of BCL2 protein		 CTD PMID:23288922 PMID:24053669 PMID:27515134 PMID:27606422 PMID:28444915 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
increases expression		 ISO hydroquinone results in decreased expression of BCL2L1 protein
hydroquinone results in increased expression of BCL2L1 protein		 CTD PMID:23288922 PMID:35561756 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO hydroquinone results in decreased expression of BDH2 mRNA CTD PMID:31256213 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of BECN1 mRNA; hydroquinone results in increased expression of BECN1 protein
PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA]		 CTD PMID:28263894 PMID:35302183 PMID:37148176 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
multiple interactions		 ISO hydroquinone results in increased cleavage of BID protein
FADD protein affects the reaction [hydroquinone results in increased cleavage of BID protein]		 CTD PMID:23288922 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression
decreases expression		 ISO hydroquinone results in increased expression of BIRC3 mRNA
hydroquinone results in decreased expression of BIRC3 mRNA		 CTD PMID:15452088 PMID:31256213 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions		 ISO hydroquinone results in decreased expression of BIRC5 protein
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]		 CTD PMID:28886972 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO hydroquinone results in decreased expression of BNIP3 mRNA CTD PMID:15452088 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bora bora, aurora kinase A activator decreases expression ISO hydroquinone results in decreased expression of BORA mRNA CTD PMID:23416264 NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322 		JBrowse link
G Bpifc BPI fold containing family C increases expression ISO hydroquinone results in increased expression of BPIFC mRNA CTD PMID:31256213 NCBI chr 7:17,848,787...17,905,993
Ensembl chr 7:17,861,007...17,905,919 		JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO hydroquinone results in increased expression of BRCA1 protein CTD PMID:29421518 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO hydroquinone results in decreased expression of BST2 mRNA CTD PMID:31256213 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO hydroquinone results in increased expression of BTG2 mRNA CTD PMID:23416264 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase multiple interactions ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC protein]; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; Chloroquine inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA]; Dactinomycin promotes the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA] CTD PMID:35561756 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression ISO hydroquinone results in decreased expression of BUB3 mRNA CTD PMID:31256213 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036 		JBrowse link
G C19h16orf74 similar to human chromosome 16 open reading frame 74 increases expression ISO hydroquinone results in increased expression of C16ORF74 mRNA CTD PMID:31256213 NCBI chr19:48,660,288...48,686,287
Ensembl chr19:48,660,288...48,686,349 		JBrowse link
G C3h15orf48 similar to human chromosome 15 open reading frame 48 increases expression ISO hydroquinone results in increased expression of C15ORF48 mRNA CTD PMID:31256213 NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006
Ensembl chr 3:109,719,897...109,724,006 		JBrowse link
G Calb2 calbindin 2 increases expression ISO hydroquinone results in increased expression of CALB2 mRNA CTD PMID:31256213 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438 		JBrowse link
G Calcb calcitonin-related polypeptide, beta increases expression ISO hydroquinone results in increased expression of CALCB mRNA CTD PMID:31256213 NCBI chr 1:168,965,383...168,970,259
Ensembl chr 1:168,966,465...168,970,125 		JBrowse link
G Calhm6 calcium homeostasis modulator family member 6 decreases expression ISO hydroquinone results in decreased expression of CALHM6 mRNA CTD PMID:31256213 NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278 		JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO hydroquinone results in decreased expression of CALML3 mRNA CTD PMID:31256213 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175 		JBrowse link
G Capn2 calpain 2 decreases activity ISO hydroquinone results in decreased activity of CAPN2 protein CTD PMID:9118890 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969 		JBrowse link
G Car3 carbonic anhydrase 3 decreases expression ISO hydroquinone results in decreased expression of CA3 mRNA CTD PMID:31256213 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Car9 carbonic anhydrase 9 decreases expression ISO hydroquinone results in decreased expression of CA9 mRNA CTD PMID:31256213 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp1 caspase 1 increases cleavage
multiple interactions		 ISO hydroquinone results in increased cleavage of CASP1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]		 CTD PMID:36646296 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CASP12 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of CASP12 protein] CTD PMID:36646296 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases degradation
increases cleavage
increases expression
decreases activity
decreases expression		 ISO
EXP		 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; hydroquinone results in decreased expression of and results in increased cleavage of CASP3 protein; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of CASP3 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; PARP1 protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]
hydroquinone results in decreased activity of CASP3 protein
[hydroquinone results in increased abundance of Reactive Oxygen Species] which results in decreased activity of CASP3 protein
hydroquinone results in decreased expression of CASP3 mRNA; hydroquinone results in decreased expression of CASP3 protein		 CTD PMID:15337166 PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 increases cleavage ISO hydroquinone results in increased cleavage of CASP4 protein CTD PMID:24053669 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp6 caspase 6 decreases expression ISO hydroquinone results in decreased expression of CASP6 mRNA CTD PMID:15452088 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp7 caspase 7 increases cleavage
increases expression
decreases activity
multiple interactions		 ISO hydroquinone results in increased cleavage of CASP7 protein
hydroquinone results in increased expression of CASP7 protein modified form
hydroquinone results in decreased activity of CASP7 protein
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein]		 CTD PMID:19064679 PMID:22960397 PMID:28886972 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
increases expression
increases activity		 ISO FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP8 protein]
hydroquinone results in increased expression of CASP8 protein
hydroquinone results in increased activity of CASP8 protein		 CTD PMID:15777082 PMID:23288922 PMID:23776099 PMID:27606422 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 decreases expression
increases activity
increases expression
multiple interactions
increases cleavage		 ISO
EXP		 hydroquinone results in decreased expression of CASP9 mRNA; hydroquinone results in decreased expression of CASP9 protein
hydroquinone results in increased activity of CASP9 protein
hydroquinone results in increased expression of CASP9 protein
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP9 protein]		 CTD PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 PMID:22302391 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases response to substance
decreases activity		 ISO
EXP		 CAT protein results in decreased susceptibility to hydroquinone
hydroquinone results in decreased activity of CAT protein		 CTD PMID:10193577 PMID:26056850 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO hydroquinone results in decreased expression of CAVIN2 mRNA CTD PMID:31256213 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147 		JBrowse link
G Cbs cystathionine beta synthase increases expression ISO hydroquinone results in increased expression of CBS mRNA CTD PMID:31256213 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccdc127 coiled-coil domain containing 127 decreases expression ISO hydroquinone results in decreased expression of CCDC127 mRNA CTD PMID:31256213 NCBI chr 1:28,928,420...28,935,885
Ensembl chr 1:28,928,325...28,935,893 		JBrowse link
G Ccdc163 coiled-coil domain containing 163 decreases expression ISO hydroquinone results in decreased expression of CCDC163 mRNA CTD PMID:31256213 NCBI chr 5:130,172,014...130,178,934
Ensembl chr 5:130,172,774...130,178,929 		JBrowse link
G Ccdc8 coiled-coil domain containing 8 decreases expression ISO hydroquinone results in decreased expression of CCDC8 mRNA CTD PMID:31256213 NCBI chr 1:77,679,521...77,682,849
Ensembl chr 1:77,679,218...77,683,090 		JBrowse link
G Ccdc88c coiled-coil domain containing 88C decreases expression ISO hydroquinone results in decreased expression of CCDC88C mRNA CTD PMID:31256213 NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO hydroquinone results in increased expression of CCL11 protein CTD PMID:17572062 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion
decreases expression
multiple interactions
increases secretion
increases expression		 ISO hydroquinone results in decreased secretion of CCL2 protein
hydroquinone results in decreased expression of CCL2 mRNA
hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 mRNA]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of CCL2 protein]
hydroquinone results in increased secretion of CCL2 protein
hydroquinone results in increased expression of CCL2 protein		 CTD PMID:17572062 PMID:20946948 PMID:22302391 PMID:22465845 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO hydroquinone results in increased expression of CCL3 protein CTD PMID:17572062 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO hydroquinone results in increased expression of CCL4 protein CTD PMID:17572062 PMID:18353026 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO hydroquinone results in increased expression of CCL5 protein CTD PMID:17572062 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn1 cellular communication network factor 1 affects expression ISO hydroquinone affects the expression of CCN1 mRNA CTD PMID:15452088 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO hydroquinone results in increased expression of CCN2 mRNA CTD PMID:31256213 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna1 cyclin A1 increases expression ISO hydroquinone results in increased expression of CCNA1 mRNA CTD PMID:31256213 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
decreases expression		 ISO Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein]
hydroquinone results in increased expression of CCND1 mRNA; hydroquinone results in increased expression of CCND1 protein		 CTD PMID:28886972 PMID:33932074 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne2 cyclin E2 increases expression ISO hydroquinone results in increased expression of CCNE2 mRNA CTD PMID:23416264 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccnf cyclin F decreases expression ISO hydroquinone results in decreased expression of CCNF mRNA CTD PMID:23416264 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101 		JBrowse link
G Ccsap centriole, cilia and spindle-associated protein decreases expression ISO hydroquinone results in decreased expression of CCSAP mRNA CTD PMID:31256213 NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753 		JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 protein] CTD PMID:20054000 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:19148301 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd86 CD86 molecule increases expression
multiple interactions		 ISO hydroquinone results in increased expression of CD86 protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein]		 CTD PMID:19148301 PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO hydroquinone results in decreased expression of CDCA2 mRNA CTD PMID:23416264 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO hydroquinone results in decreased expression of CDCA7 mRNA CTD PMID:31256213 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353 		JBrowse link
G Cdh26 cadherin 26 decreases expression ISO hydroquinone results in decreased expression of CDH26 mRNA CTD PMID:31256213 NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO hydroquinone results in increased expression of CDKN1A mRNA; hydroquinone results in increased expression of CDKN1A protein
SIRT1 protein affects the reaction [hydroquinone results in increased expression of CDKN1A protein]		 CTD PMID:23416264 PMID:27515134 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO hydroquinone results in decreased expression of CDKN1C mRNA CTD PMID:31256213 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
decreases expression		 ISO CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of RB1 protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of TP53 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of CDKN2A protein]
hydroquinone results in decreased expression of CDKN2A mRNA; hydroquinone results in decreased expression of CDKN2A protein		 CTD PMID:33771647 PMID:33932074 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdsn corneodesmosin increases expression ISO hydroquinone results in increased expression of CDSN mRNA CTD PMID:31256213 NCBI chr20:3,179,432...3,184,252
Ensembl chr20:3,179,438...3,184,250 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 increases expression ISO hydroquinone results in increased expression of CEMIP mRNA CTD PMID:31256213 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Cenpa centromere protein A decreases expression ISO hydroquinone results in decreased expression of CENPA mRNA CTD PMID:23416264 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cep15 centrosomal protein 15 decreases expression ISO hydroquinone results in decreased expression of CEP15 mRNA CTD PMID:31256213 NCBI chr15:12,815,159...12,835,115
Ensembl chr15:12,818,385...12,833,838 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO hydroquinone results in increased expression of CES1 mRNA CTD PMID:31256213 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cfap44 cilia and flagella associated protein 44 decreases expression ISO hydroquinone results in decreased expression of CFAP44 mRNA CTD PMID:31256213 NCBI chr11:56,199,772...56,283,964
Ensembl chr11:56,201,049...56,283,986 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO hydroquinone results in increased expression of CFLAR mRNA CTD PMID:31256213 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression ISO hydroquinone results in increased expression of CH25H mRNA CTD PMID:31256213 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression
decreases expression		 ISO hydroquinone results in increased expression of CHAC1 mRNA
hydroquinone results in decreased expression of CHAC1 mRNA		 CTD PMID:29221148 PMID:31256213 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Chp2 calcineurin-like EF hand protein 2 decreases expression ISO hydroquinone results in decreased expression of CHP2 mRNA CTD PMID:31256213 NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139 		JBrowse link
G Chst2 carbohydrate sulfotransferase 2 increases expression ISO hydroquinone results in increased expression of CHST2 mRNA CTD PMID:31256213 NCBI chr 8:95,960,067...95,966,312
Ensembl chr 8:95,959,826...95,966,955 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] CTD PMID:23288922 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Clca4 chloride channel accessory 4 decreases expression ISO hydroquinone results in decreased expression of CLCA4 mRNA CTD PMID:31256213 NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089 		JBrowse link
G Cldn8 claudin 8 decreases expression ISO hydroquinone results in decreased expression of CLDN8 mRNA CTD PMID:31256213 NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513 		JBrowse link
G Clic3 chloride intracellular channel 3 increases expression ISO hydroquinone results in increased expression of CLIC3 mRNA CTD PMID:31256213 NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018 		JBrowse link
G Clmp CXADR-like membrane protein increases expression ISO hydroquinone results in increased expression of CLMP mRNA CTD PMID:31256213 NCBI chr 8:41,060,527...41,168,841
Ensembl chr 8:41,060,799...41,168,838 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO hydroquinone results in decreased expression of CMPK2 mRNA CTD PMID:31256213 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183 		JBrowse link
G Cnfn cornifelin increases expression ISO hydroquinone results in increased expression of CNFN mRNA CTD PMID:31256213 NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747 		JBrowse link
G Cnmd chondromodulin increases response to substance
increases expression
multiple interactions		 ISO CNMD protein results in increased susceptibility to hydroquinone
hydroquinone results in increased expression of CNMD mRNA
Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; hydroquinone results in increased expression of and results in increased secretion of CNMD protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]		 CTD PMID:19525446 NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions		 ISO hydroquinone results in increased expression of COL1A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]		 CTD PMID:18055817 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased expression of and results in increased secretion of TNF protein; [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; [COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein CTD PMID:29908986 PMID:29935983 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression
increases expression
multiple interactions		 ISO hydroquinone results in decreased expression of COL4A1 mRNA
hydroquinone results in increased expression of COL4A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]		 CTD PMID:18055817 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO hydroquinone results in decreased expression of COL5A2 mRNA CTD PMID:31256213 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Crct1 cysteine-rich C-terminal 1 increases expression ISO hydroquinone results in increased expression of CRCT1 mRNA CTD PMID:31256213 NCBI chr 2:178,633,789...178,635,274
Ensembl chr 2:178,634,092...178,634,394 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of CREB1 protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone promotes the reaction [CREB1 protein binds to PPP2CA promoter] CTD PMID:23288922 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression ISO hydroquinone results in increased expression of CRISPLD2 mRNA CTD PMID:31256213 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465 		JBrowse link
G Crybg2 crystallin beta-gamma domain containing 2 increases expression ISO hydroquinone results in increased expression of CRYBG2 mRNA CTD PMID:29221148 NCBI chr 5:146,286,406...146,318,417
Ensembl chr 5:146,286,925...146,323,666 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO hydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
decreases secretion		 ISO [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein
hydroquinone results in decreased secretion of CSF2 protein
hydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide]		 CTD PMID:7884313 PMID:15129224 PMID:23559866 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 increases expression ISO hydroquinone results in increased expression of CSGALNACT1 mRNA CTD PMID:31256213 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Csrnp3 cysteine and serine rich nuclear protein 3 decreases expression ISO hydroquinone results in decreased expression of CSRNP3 mRNA CTD PMID:31256213 NCBI chr 3:50,498,379...50,695,598
Ensembl chr 3:50,498,633...50,685,950 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO hydroquinone results in decreased expression of CSRP2 mRNA CTD PMID:31256213 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745 		JBrowse link
G Cst6 cystatin E/M increases expression ISO hydroquinone results in increased expression of CST6 mRNA CTD PMID:31256213 NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030 		JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO hydroquinone results in increased expression of CTH mRNA CTD PMID:31256213 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
affects localization
decreases expression		 ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]; hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein] CTD PMID:28886972 PMID:30567741 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression
decreases secretion		 ISO hydroquinone results in decreased expression of CXCL12 mRNA
hydroquinone results in decreased secretion of CXCL12 protein		 CTD PMID:22960397 PMID:23559866 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cycs cytochrome c, somatic affects localization
increases expression
multiple interactions		 ISO hydroquinone affects the localization of CYCS protein
hydroquinone results in increased expression of CYCS protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYCS protein]		 CTD PMID:15777082 PMID:15816534 PMID:35123993 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects response to substance
multiple interactions
increases expression		 ISO CYP1A1 protein affects the susceptibility to hydroquinone
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]
hydroquinone results in increased expression of CYP1A1 mRNA; hydroquinone results in increased expression of CYP1A1 protein		 CTD PMID:8242868 PMID:23416264 PMID:31256213 PMID:35123993 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO hydroquinone results in increased expression of CYP1B1 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP [CYP2B1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone CTD PMID:8211999 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects response to substance ISO CYP2B1 protein affects the susceptibility to hydroquinone CTD PMID:8242868 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO [CYP2D6 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression		 EXP
ISO		 [CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone; [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone; [Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]
hydroquinone results in increased expression of CYP2E1 mRNA
Resveratrol inhibits the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]
hydroquinone results in increased expression of CYP2E1 mRNA; hydroquinone results in increased expression of CYP2E1 protein
[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]		 CTD PMID:8211999 PMID:15051535 PMID:23202692 PMID:30567741 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [CYP3A5 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO hydroquinone results in increased expression of CYP4F18 mRNA; hydroquinone results in increased expression of CYP4F18 protein CTD PMID:23940708 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940 		JBrowse link
G Cysrt1 cysteine rich tail 1 increases expression ISO hydroquinone results in increased expression of CYSRT1 mRNA CTD PMID:31256213 NCBI chr 3:8,054,195...8,057,846
Ensembl chr 3:8,053,482...8,059,721 		JBrowse link
G Dap death-associated protein decreases expression ISO hydroquinone results in decreased expression of DAP mRNA CTD PMID:15452088 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752 		JBrowse link
G Dapl1 death associated protein-like 1 decreases expression ISO hydroquinone results in decreased expression of DAPL1 mRNA CTD PMID:31256213 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940 		JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 increases expression ISO hydroquinone results in increased expression of DAPP1 mRNA CTD PMID:31256213 NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression ISO hydroquinone results in decreased expression of DBT mRNA CTD PMID:31256213 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609 		JBrowse link
G Dcun1d3 defective in cullin neddylation 1 domain containing 3 increases expression ISO hydroquinone results in increased expression of DCUN1D3 mRNA CTD PMID:31256213 NCBI chr 1:174,243,001...174,285,647
Ensembl chr 1:66,494,848...66,496,343
Ensembl chr 1:66,494,848...66,496,343 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO hydroquinone results in decreased expression of DDAH1 mRNA CTD PMID:31256213 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of DDIT3 mRNA; hydroquinone results in increased expression of DDIT3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; hydroquinone results in increased expression of and affects the localization of DDIT3 protein; ursodoxicoltaurine inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]
[XBP1 protein affects the susceptibility to hydroquinone] which affects the expression of DDIT3 protein; hydroquinone promotes the reaction [XBP1 protein affects the expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 protein]		 CTD PMID:23416264 PMID:24053669 PMID:31256213 PMID:32334435 PMID:36646296 More... NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO hydroquinone results in increased expression of DDIT4 mRNA CTD PMID:23416264 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 decreases expression ISO hydroquinone results in decreased expression of DDX60 mRNA CTD PMID:31256213 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Depdc7 DEP domain containing 7 decreases expression ISO hydroquinone results in decreased expression of DEPDC7 mRNA CTD PMID:31256213 NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein decreases expression ISO hydroquinone results in decreased expression of DEPTOR mRNA CTD PMID:29221148 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO hydroquinone results in decreased expression of DFFB mRNA CTD PMID:31256213 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects expression ISO hydroquinone affects the expression of DKK1 mRNA CTD PMID:22960397 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO hydroquinone results in increased expression of DNAJA1 mRNA CTD PMID:15452088 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO hydroquinone results in increased expression of DNAJB1 mRNA CTD PMID:15452088 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dner delta/notch-like EGF repeat containing decreases expression ISO hydroquinone results in decreased expression of DNER mRNA CTD PMID:31256213 NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression
increases expression
affects expression		 ISO hydroquinone results in decreased expression of DNMT1 mRNA; hydroquinone results in decreased expression of DNMT1 protein
hydroquinone results in increased expression of DNMT1 mRNA
hydroquinone affects the expression of DNMT1 mRNA		 CTD PMID:22245671 PMID:27979589 PMID:31899212 PMID:34612549 PMID:35135009 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
affects expression
increases expression		 ISO hydroquinone results in decreased expression of DNMT3A mRNA; hydroquinone results in decreased expression of DNMT3A protein
hydroquinone affects the expression of DNMT3A mRNA
hydroquinone results in increased expression of DNMT3A mRNA		 CTD PMID:22245671 PMID:27979589 PMID:31899212 PMID:34612549 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions
affects expression		 ISO hydroquinone results in decreased expression of DNMT3B mRNA
Decitabine affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]; trichostatin A affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]		 CTD PMID:22245671 PMID:31899212 PMID:34612549 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L decreases expression ISO hydroquinone results in decreased expression of DTX3L mRNA CTD PMID:31256213 NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO hydroquinone results in increased expression of DUSP1 protein CTD PMID:23290930 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp19 dual specificity phosphatase 19 decreases expression ISO hydroquinone results in decreased expression of DUSP19 mRNA CTD PMID:31256213 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO hydroquinone results in increased expression of DUSP5 mRNA CTD PMID:31256213 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO hydroquinone results in increased expression of DUSP6 mRNA CTD PMID:31256213 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 decreases expression ISO hydroquinone results in decreased expression of DZIP1 mRNA CTD PMID:31256213 NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066 		JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO hydroquinone results in increased expression of E2F1 mRNA; hydroquinone results in increased expression of E2F1 protein CTD PMID:33932074 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E4f1 E4F transcription factor 1 increases expression
affects response to substance
multiple interactions		 ISO hydroquinone results in increased expression of E4F1 mRNA; hydroquinone results in increased expression of E4F1 protein
E4F1 protein affects the susceptibility to hydroquinone
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form		 CTD PMID:30448557 PMID:30506647 NCBI chr10:13,471,478...13,495,018
Ensembl chr10:13,474,456...13,485,974 		JBrowse link
G Ecm2 extracellular matrix protein 2 increases expression ISO hydroquinone results in increased expression of ECM2 mRNA CTD PMID:31256213 NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516 		JBrowse link
G Edn1 endothelin 1 decreases expression ISO hydroquinone results in decreased expression of EDN1 mRNA CTD PMID:31256213 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 decreases expression ISO hydroquinone results in decreased expression of EDN2 mRNA CTD PMID:31256213 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO hydroquinone results in decreased expression of EEF2K mRNA CTD PMID:31256213 NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164 		JBrowse link
G Efna1 ephrin A1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of EFNA1 mRNA CTD PMID:32198055 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Egr3 early growth response 3 increases expression ISO hydroquinone results in increased expression of EGR3 mRNA CTD PMID:31256213 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO hydroquinone results in decreased expression of EHMT2 protein CTD PMID:27979589 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Eid3 EP300 interacting inhibitor of differentiation 3 decreases expression ISO hydroquinone results in decreased expression of EID3 mRNA CTD PMID:31256213 NCBI chr 7:20,860,073...20,861,395 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression
multiple interactions		 ISO hydroquinone results in increased phosphorylation of EIF2AK3 protein
hydroquinone results in increased expression of EIF2AK3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of EIF2AK3 protein]		 CTD PMID:24053669 PMID:36646296 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation		 ISO XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased phosphorylation of EIF2S1 protein] CTD PMID:24053669 PMID:37148176 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO hydroquinone results in increased expression of EIF4EBP1 mRNA CTD PMID:31256213 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 multiple interactions
increases degradation
decreases expression		 ISO ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in increased degradation of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]
hydroquinone results in increased degradation of ELAVL1 mRNA
hydroquinone results in decreased expression of ELAVL1 mRNA; hydroquinone results in decreased expression of ELAVL1 protein		 CTD PMID:35302183 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784 		JBrowse link
G Elavl2 ELAV like RNA binding protein 2 multiple interactions ISO [[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein] CTD PMID:35302183 NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097 		JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO hydroquinone results in increased expression of ELF3 mRNA CTD PMID:23416264 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481 		JBrowse link
G Elf5 E74 like ETS transcription factor 5 increases expression ISO hydroquinone results in increased expression of ELF5 mRNA CTD PMID:31256213 NCBI chr 3:89,808,837...89,836,977
Ensembl chr 3:89,797,880...89,836,973 		JBrowse link
G Elmod1 ELMO domain containing 1 increases expression ISO hydroquinone results in increased expression of ELMOD1 mRNA CTD PMID:31256213 NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 increases expression ISO hydroquinone results in increased expression of ELOVL4 mRNA CTD PMID:31256213 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO hydroquinone results in decreased expression of ELOVL5 mRNA CTD PMID:31256213 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 decreases expression ISO hydroquinone results in decreased expression of ELP2 mRNA CTD PMID:31256213 NCBI chr18:15,885,940...15,921,564
Ensembl chr18:15,885,934...15,921,599 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 increases expression ISO hydroquinone results in increased expression of EPB41L3 mRNA CTD PMID:31256213 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] CTD PMID:8211999 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Eps8l1 EPS8-like 1 increases expression ISO hydroquinone results in increased expression of EPS8L1 mRNA CTD PMID:31256213 NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO hydroquinone results in decreased expression of ERBB2 mRNA CTD PMID:22245671 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ereg epiregulin increases expression ISO hydroquinone results in increased expression of EREG mRNA CTD PMID:31256213 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Erich5 glutamate-rich 5 decreases expression ISO hydroquinone results in decreased expression of ERICH5 mRNA CTD PMID:31256213 NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ERN1 protein] CTD PMID:36646296 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO hydroquinone results in decreased expression of ESR1 mRNA CTD PMID:31256213 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Etv4 ETS variant transcription factor 4 increases expression ISO hydroquinone results in increased expression of ETV4 mRNA CTD PMID:31256213 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974 		JBrowse link
G Exosc3 exosome component 3 decreases expression ISO hydroquinone results in decreased expression of EXOSC3 mRNA CTD PMID:31256213 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060 		JBrowse link
G Exosc6 exosome component 6 increases expression ISO hydroquinone results in increased expression of EXOSC6 mRNA CTD PMID:31256213 NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO hydroquinone results in decreased expression of EZH2 protein CTD PMID:27979589 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO hydroquinone results in decreased expression of F2R mRNA CTD PMID:31256213 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of FABP4 mRNA CTD PMID:37245849 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fadd Fas associated via death domain decreases expression
multiple interactions		 ISO hydroquinone results in decreased expression of FADD mRNA
FADD protein affects the reaction [hydroquinone results in increased cleavage of BID protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]		 CTD PMID:15452088 PMID:23288922 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fam117b family with sequence similarity 117, member B decreases expression ISO hydroquinone results in decreased expression of FAM117B mRNA CTD PMID:31256213 NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483 		JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression ISO hydroquinone results in decreased expression of FAM13A mRNA CTD PMID:31256213 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860 		JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO hydroquinone results in increased expression of FAM43A mRNA CTD PMID:31256213 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401 		JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO hydroquinone results in decreased expression of FAM83D mRNA CTD PMID:23416264 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192 		JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions		 ISO hydroquinone results in increased expression of FAS protein
[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein		 CTD PMID:23776099 PMID:28444915 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression ISO hydroquinone results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion multiple interactions ISO FAU protein affects the reaction [hydroquinone results in increased expression of and results in increased activity of NQO1 protein]; FAU protein affects the reaction [hydroquinone results in increased expression of H2AX protein] CTD PMID:22687461 NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742 		JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO hydroquinone results in decreased expression of FBXO5 mRNA CTD PMID:23416264 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO hydroquinone results in decreased expression of FGFR3 mRNA CTD PMID:31256213 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fibin fin bud initiation factor homolog increases expression ISO hydroquinone results in increased expression of FIBIN mRNA CTD PMID:31256213 NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676 		JBrowse link
G Flg filaggrin increases expression ISO hydroquinone results in increased expression of FLG mRNA; hydroquinone results in increased expression of FLG protein CTD PMID:25240866 NCBI chr 2:178,884,793...178,912,986 JBrowse link
G Flg2 filaggrin 2 increases expression ISO hydroquinone results in increased expression of FLG2 mRNA CTD PMID:25240866 NCBI chr 2:178,789,792...178,802,232 JBrowse link
G Fn1 fibronectin 1 affects expression ISO hydroquinone affects the expression of FN1 mRNA CTD PMID:15452088 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
increases phosphorylation
multiple interactions		 ISO hydroquinone results in decreased expression of FOS mRNA
hydroquinone results in increased phosphorylation of FOS protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of FOS protein]; FOS protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; hydroquinone promotes the reaction [FOS protein binds to MIR122 promoter]		 CTD PMID:15452088 PMID:23791922 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO hydroquinone results in increased expression of FOSL1 mRNA CTD PMID:31256213 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fry FRY microtubule binding protein increases expression ISO hydroquinone results in increased expression of FRY mRNA CTD PMID:31256213 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116 		JBrowse link
G Fsip1 fibrous sheath interacting protein 1 increases expression ISO hydroquinone results in increased expression of FSIP1 mRNA CTD PMID:31256213 NCBI chr 3:105,074,584...105,217,180
Ensembl chr 3:105,068,543...105,217,167 		JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO hydroquinone results in increased expression of FTH1 mRNA; hydroquinone results in increased expression of FTH1 protein CTD PMID:15452088 PMID:23738040 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Fut1 fucosyltransferase 1 decreases expression ISO hydroquinone results in decreased expression of FUT1 mRNA CTD PMID:29221148 NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616 		JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression ISO hydroquinone results in decreased expression of FZD2 mRNA CTD PMID:31256213 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G G0s2 G0/G1switch 2 increases expression ISO hydroquinone results in increased expression of G0S2 mRNA CTD PMID:31256213 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO hydroquinone results in increased expression of GADD45A mRNA CTD PMID:23416264 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO hydroquinone results in decreased expression of GAS1 mRNA CTD PMID:31256213 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO hydroquinone results in decreased expression of GASK1B mRNA CTD PMID:31256213 NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477 		JBrowse link
G Gata1 GATA binding protein 1 decreases expression
multiple interactions		 ISO hydroquinone results in decreased expression of GATA1 mRNA
Decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]]; hydroquinone inhibits the reaction [GATA1 protein binds to HBA1 gene]; hydroquinone inhibits the reaction [GATA1 protein binds to HBD gene]; hydroquinone inhibits the reaction [GATA1 protein binds to HBG1 gene]; hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]		 CTD PMID:21414390 PMID:23973255 PMID:37329354 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gata2 GATA binding protein 2 multiple interactions
decreases expression		 ISO hydroquinone affects the reaction [Hemin affects the expression of GATA2 mRNA]; hydroquinone inhibits the reaction [Hemin results in decreased expression of GATA2 protein]; hydroquinone promotes the reaction [GATA2 protein binds to HBB gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBG2 gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBM gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBP1 gene]; hydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroquinone results in decreased expression of GATA2 mRNA		 CTD PMID:21414390 PMID:37329354 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO hydroquinone results in decreased expression of GBP2 mRNA CTD PMID:31256213 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
affects methylation		 ISO hydroquinone results in increased expression of GCLC mRNA; hydroquinone results in increased expression of GCLC protein
[hydroquinone affects the methylation of GCLC promoter] which results in decreased abundance of 5-Methylcytosine; [hydroquinone affects the methylation of GCLC promoter] which results in increased abundance of 5-hydroxymethylcytosine; Resveratrol promotes the reaction [hydroquinone results in increased expression of GCLC mRNA]; TET1 protein affects the reaction [hydroquinone results in increased expression of GCLC mRNA]		 CTD PMID:23290930 PMID:23940045 PMID:30547568 PMID:32334435 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO hydroquinone results in increased expression of GCLM mRNA; hydroquinone results in increased expression of GCLM protein CTD PMID:21059386 PMID:30547568 PMID:31256213 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gda guanine deaminase increases expression ISO hydroquinone results in increased expression of GDA mRNA CTD PMID:31256213 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO hydroquinone results in increased expression of GDF15 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO hydroquinone results in increased expression of GDPD3 mRNA CTD PMID:31256213 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 increases expression ISO hydroquinone results in increased expression of GFPT1 mRNA CTD PMID:31256213 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471 		JBrowse link
G Gk glycerol kinase increases expression ISO hydroquinone results in increased expression of GK mRNA CTD PMID:31256213 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Glmp glycosylated lysosomal membrane protein decreases expression ISO hydroquinone results in decreased expression of GLMP mRNA CTD PMID:31256213 NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960 		JBrowse link
G Glrx glutaredoxin increases expression ISO hydroquinone results in increased expression of GLRX mRNA CTD PMID:31256213 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression ISO hydroquinone results in decreased expression of GLUL mRNA CTD PMID:31256213 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gmpr guanosine monophosphate reductase decreases expression ISO hydroquinone results in decreased expression of GMPR mRNA CTD PMID:31256213 NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621 		JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 decreases expression ISO hydroquinone results in decreased expression of GOSR2 mRNA CTD PMID:31256213 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO hydroquinone results in increased expression of GOT1 mRNA CTD PMID:31256213 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO hydroquinone results in increased expression of GPAT3 mRNA CTD PMID:31256213 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490 		JBrowse link
G Gpr155 G protein-coupled receptor 155 decreases expression ISO hydroquinone results in decreased expression of GPR155 mRNA CTD PMID:31256213 NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275 		JBrowse link
G Gpr15lg G protein-coupled receptor 15 ligand decreases expression ISO hydroquinone results in decreased expression of GPR15LG mRNA CTD PMID:31256213 NCBI chr16:12,868,270...12,875,876
Ensembl chr16:12,868,270...12,875,876 		JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A decreases expression ISO hydroquinone results in decreased expression of GPRC5A mRNA CTD PMID:31256213 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO hydroquinone results in increased expression of GPX2 mRNA CTD PMID:31256213 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO hydroquinone results in increased expression of GRB10 mRNA CTD PMID:31256213 NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806 		JBrowse link
G Grb2 growth factor receptor bound protein 2 affects expression ISO hydroquinone affects the expression of GRB2 protein CTD PMID:20021034 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Grhl1 grainyhead-like transcription factor 1 increases expression ISO hydroquinone results in increased expression of GRHL1 mRNA CTD PMID:31256213 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301 		JBrowse link
G Gsdmd gasdermin D increases expression
multiple interactions		 ISO hydroquinone results in increased expression of GSDMD protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]		 CTD PMID:36646296 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO hydroquinone results in increased expression of and results in decreased phosphorylation of and results in increased activity of GSK3B protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein] CTD PMID:28886972 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO hydroquinone inhibits the reaction [Peroxynitrous Acid results in decreased activity of GSR protein] CTD PMID:15831208 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gss glutathione synthetase increases expression
multiple interactions		 ISO hydroquinone results in increased expression of GSS protein
NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]		 CTD PMID:21059386 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 affects the susceptibility to hydroquinone; GSTM1 gene polymorphism affects the susceptibility to hydroquinone CTD PMID:15141365 PMID:19778234 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects response to substance ISO GSTP1 affects the susceptibility to hydroquinone CTD PMID:19778234 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression
affects response to substance		 ISO hydroquinone results in increased expression of GSTT1 mRNA
GSTT1 affects the susceptibility to hydroquinone		 CTD PMID:19778234 PMID:23290930 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gtpbp2 GTP binding protein 2 increases expression ISO hydroquinone results in increased expression of GTPBP2 mRNA CTD PMID:31256213 NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO hydroquinone results in increased expression of GUCY1B1 mRNA CTD PMID:31256213 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G Gvin1 GTPase, very large interferon inducible 1 decreases expression ISO hydroquinone results in decreased expression of GVINP1 mRNA CTD PMID:31256213 NCBI chr 1:160,279,767...160,306,701
Ensembl chr 1:160,277,126...160,306,331 		JBrowse link
G Gypa glycophorin A decreases expression ISO hydroquinone results in decreased expression of GYPA protein CTD PMID:21414390 NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822 		JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-4 mRNA CTD PMID:23416264 NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403 		JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-5 mRNA CTD PMID:23416264 NCBI chr17:42,726,132...42,727,162
Ensembl chr17:42,726,127...42,769,160 		JBrowse link
G H2ac12 H2A clustered histone 12 decreases expression ISO hydroquinone results in decreased expression of H2AC12 mRNA CTD PMID:23416264 NCBI chr17:42,486,415...42,486,880
Ensembl chr17:42,486,415...42,486,941 		JBrowse link
G H2ac18 H2A clustered histone 18 decreases expression ISO hydroquinone results in decreased expression of H2AC18 mRNA CTD PMID:23416264 NCBI chr 2:183,808,398...183,808,992 JBrowse link
G H2ac20 H2A clustered histone 20 decreases expression ISO hydroquinone results in decreased expression of H2AC20 mRNA CTD PMID:23416264 NCBI chr 2:183,779,879...183,780,357 JBrowse link
G H2ac21 H2A clustered histone 21 decreases expression ISO hydroquinone results in decreased expression of H2AC21 mRNA CTD PMID:23416264 NCBI chr 2:183,779,355...183,779,788 JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression
increases phosphorylation
affects localization		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; [ABT-737 co-treated with hydroquinone] results in increased expression of H2AX protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [SIRT1 protein affects the susceptibility to hydroquinone] which affects the expression of H2AX protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; POLH protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; WRN gene mutant form promotes the reaction [hydroquinone results in increased expression of H2AX protein alternative form]; WRN protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
FAU protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
hydroquinone results in increased phosphorylation of H2AX protein
hydroquinone affects the localization of H2AX protein modified form
hydroquinone results in increased expression of H2AX protein; hydroquinone results in increased expression of H2AX protein alternative form		 CTD PMID:17875398 PMID:18835433 PMID:20036648 PMID:21267443 PMID:22687461 More... NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G H4c14 H4 clustered histone 14 decreases expression ISO hydroquinone results in decreased expression of H4C2 mRNA CTD PMID:23416264 NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048 		JBrowse link
G H4cl1 histone H4C like 1 decreases expression ISO hydroquinone results in decreased expression of H4C6 mRNA CTD PMID:23416264 NCBI chr17:41,368,743...41,426,735 JBrowse link
G H4f3 H1.3 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-3 mRNA CTD PMID:23416264 NCBI chr17:41,551,524...41,552,303
Ensembl chr17:41,529,667...41,552,334 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions ISO hydroquinone inhibits the reaction [GATA1 protein binds to HBA1 gene] CTD PMID:37329354 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbb hemoglobin subunit beta multiple interactions
decreases methylation		 ISO Decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]; hydroquinone promotes the reaction [GATA2 protein binds to HBB gene]
hydroquinone results in decreased methylation of HBB promoter		 CTD PMID:21414390 PMID:23973255 PMID:37329354 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain multiple interactions ISO hydroquinone inhibits the reaction [GATA1 protein binds to HBD gene] CTD PMID:37329354 NCBI chr 1:158,224,175...158,231,675
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO hydroquinone results in increased expression of HBEGF mRNA CTD PMID:31256213 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hbg1 hemoglobin subunit gamma 1 multiple interactions ISO hydroquinone inhibits the reaction [GATA1 protein binds to HBG1 gene] CTD PMID:37329354 NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425 		JBrowse link
G Hbp1 HMG-box transcription factor 1 multiple interactions ISO hydroquinone promotes the reaction [GATA2 protein binds to HBP1 gene] CTD PMID:37329354 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787 		JBrowse link
G Hdac1 histone deacetylase 1 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of HDAC1 mRNA; hydroquinone results in increased expression of HDAC1 protein
trichostatin A inhibits the reaction [hydroquinone results in increased expression of HDAC1 mRNA]		 CTD PMID:27220438 PMID:30448557 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of HDAC2 mRNA; hydroquinone results in increased expression of HDAC2 protein
trichostatin A inhibits the reaction [hydroquinone results in increased expression of HDAC2 mRNA]		 CTD PMID:27220438 PMID:30448557 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hdac9 histone deacetylase 9 increases expression ISO hydroquinone results in increased expression of HDAC9 mRNA CTD PMID:31256213 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
G Hfe homeostatic iron regulator decreases expression ISO hydroquinone results in decreased expression of HFE mRNA CTD PMID:31256213 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hist1h4m histone cluster 1, H4m decreases expression ISO hydroquinone results in decreased expression of H4C1 mRNA CTD PMID:23416264 NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958 		JBrowse link
G Hjurp Holliday junction recognition protein decreases expression ISO hydroquinone results in decreased expression of HJURP mRNA CTD PMID:23416264 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728 		JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions ISO decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] CTD PMID:21414390 PMID:23973255 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO hydroquinone results in decreased expression of HMGB2 mRNA CTD PMID:23416264 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of HMOX1 mRNA; hydroquinone results in increased expression of HMOX1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; AG 1879 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; bisindolylmaleimide I inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Cysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Dithiothreitol inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; [Resveratrol co-treated with hydroquinone] results in increased expression of HMOX1 protein; ferric chloride promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; Resveratrol promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]		 CTD PMID:17464197 PMID:21059386 PMID:23290930 PMID:28645578 PMID:29508652 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hotairm1 Hoxa transcript antisense RNA, myeloid-specific 1 multiple interactions
affects expression
affects methylation		 ISO Decitabine affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; Decitabine affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter]; trichostatin A affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; trichostatin A affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter] CTD PMID:31899212 NCBI chr 4:81,258,793...81,262,291 JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
affects expression		 ISO 3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of HRAS protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of HRAS protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]
hydroquinone affects the expression of HRAS mRNA; hydroquinone affects the expression of HRAS protein		 CTD PMID:26047893 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression ISO hydroquinone results in increased expression of HSD17B2 mRNA CTD PMID:31256213 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 increases expression ISO hydroquinone results in increased expression of HSPA13 mRNA CTD PMID:31256213 NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO hydroquinone results in increased expression of HSPA2 mRNA CTD PMID:15452088 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of HSPA5 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]		 CTD PMID:24053669 PMID:36646296 PMID:37148176 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A decreases expression ISO hydroquinone results in decreased expression of HTR1A protein CTD PMID:27606422 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B decreases expression ISO hydroquinone results in decreased expression of HTR1B protein CTD PMID:27606422 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO hydroquinone results in decreased expression of HYLS1 mRNA CTD PMID:23416264 NCBI chr 8:33,912,692...33,921,760
Ensembl chr 8:33,912,692...33,921,760 		JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO hydroquinone results in increased expression of ID1 mRNA CTD PMID:31256213 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression ISO hydroquinone results in decreased expression of ID3 mRNA CTD PMID:31256213 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Id4 inhibitor of DNA binding 4 increases expression ISO hydroquinone results in increased expression of ID4 mRNA CTD PMID:31256213 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470 		JBrowse link
G Ier3 immediate early response 3 increases expression ISO hydroquinone results in increased expression of IER3 mRNA CTD PMID:31256213 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO hydroquinone results in decreased expression of IFI44 mRNA CTD PMID:31256213 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844 		JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO hydroquinone results in decreased expression of IFI44L mRNA CTD PMID:31256213 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO hydroquinone results in decreased expression of IFIH1 mRNA CTD PMID:31256213 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO hydroquinone results in decreased expression of IFIT3 mRNA CTD PMID:31256213 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 decreases expression ISO hydroquinone results in decreased expression of IFITM1 mRNA CTD PMID:31256213 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Ifng interferon gamma multiple interactions ISO hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased expression of IFNG protein]; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroquinone] results in increased abundance of Nitric Oxide] CTD PMID:3137358 PMID:7884313 PMID:22465845 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO hydroquinone results in increased expression of IFRD1 mRNA CTD PMID:31256213 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form] CTD PMID:28886972 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression ISO hydroquinone results in decreased expression of IGFBP3 mRNA CTD PMID:31256213 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:20054000 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases secretion		 ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]
hydroquinone results in increased secretion of IL10 protein
hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]		 CTD PMID:17464197 PMID:17572062 PMID:23559866 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression		 ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]
hydroquinone results in increased expression of IL12B mRNA		 CTD PMID:15894107 PMID:17464197 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il15 interleukin 15 decreases secretion ISO hydroquinone results in decreased secretion of IL15 protein CTD PMID:23559866 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il17a interleukin 17A increases secretion EXP hydroquinone results in increased secretion of IL17A protein CTD PMID:29935983 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 multiple interactions
increases secretion		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased secretion of IL18 protein] CTD PMID:36646296 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
decreases cleavage		 ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]
Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]
hydroquinone results in increased expression of IL1A mRNA; hydroquinone results in increased expression of IL1A protein
hydroquinone results in decreased cleavage of IL1A protein		 CTD PMID:1868253 PMID:8548860 PMID:9118901 PMID:28836394 PMID:31256213 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta decreases cleavage
multiple interactions
increases expression
decreases secretion		 ISO
EXP		 hydroquinone results in decreased cleavage of IL1B protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; hydroquinone results in increased expression of and results in increased secretion of IL1B protein
hydroquinone results in increased expression of IL1B mRNA
hydroquinone results in decreased secretion of IL1B protein
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of IL1B mRNA; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]		 CTD PMID:8548860 PMID:9118901 PMID:17464197 PMID:19148301 PMID:22717997 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1f10 interleukin 1 family member 10 increases expression ISO hydroquinone results in increased expression of IL1F10 mRNA CTD PMID:31256213 NCBI chr 3:7,072,511...7,075,439
Ensembl chr 3:7,072,511...7,075,439 		JBrowse link
G Il1rn interleukin 1 receptor antagonist increases secretion ISO hydroquinone results in increased secretion of IL1RN protein CTD PMID:23559866 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein] CTD PMID:9571986 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA] CTD PMID:17464197 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il33 interleukin 33 decreases expression ISO hydroquinone results in decreased expression of IL33 mRNA CTD PMID:31256213 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il36g interleukin 36, gamma increases expression ISO hydroquinone results in increased expression of IL36G mRNA CTD PMID:31256213 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480 		JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression ISO hydroquinone results in increased expression of IL36RN mRNA CTD PMID:31256213 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 mRNA]; hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 protein] CTD PMID:12153512 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion		 EXP
ISO		 [COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
[hydroquinone co-treated with TNF protein] results in increased secretion of IL6 protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
hydroquinone results in decreased secretion of IL6 protein		 CTD PMID:17464197 PMID:19148301 PMID:20054000 PMID:22302391 PMID:22717997 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhba inhibin subunit beta A increases expression ISO hydroquinone results in increased expression of INHBA mRNA CTD PMID:31256213 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Inhbe inhibin subunit beta E decreases expression ISO hydroquinone results in decreased expression of INHBE mRNA CTD PMID:29221148 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B increases expression ISO hydroquinone results in increased expression of INPP4B mRNA CTD PMID:31256213 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 decreases expression ISO hydroquinone results in decreased expression of IRAK1 mRNA CTD PMID:30090394 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO hydroquinone inhibits the reaction [AKT1 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [AKT2 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [AKT3 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [TICAM1 protein results in increased phosphorylation of IRF3 protein] CTD PMID:28883758 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO hydroquinone results in decreased expression of IRS1 mRNA CTD PMID:31256213 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO hydroquinone results in decreased expression of ISG15 mRNA CTD PMID:31256213 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases activity
decreases expression		 ISO hydroquinone results in decreased activity of ITGB1 protein
hydroquinone results in decreased expression of ITGB1 mRNA
hydroquinone results in decreased expression of ITGB1 protein		 CTD PMID:17464197 PMID:19148301 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression
increases expression		 ISO hydroquinone results in decreased expression of ITGB2 protein
hydroquinone results in decreased expression of ITGB2 mRNA
hydroquinone results in increased expression of ITGB2 protein		 CTD PMID:17464197 PMID:19148301 PMID:21664406 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO hydroquinone results in increased expression of ITGB3 protein CTD PMID:21664406 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Ivl involucrin increases expression ISO hydroquinone results in increased expression of IVL mRNA; hydroquinone results in increased expression of IVL protein CTD PMID:25240866 PMID:31256213 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO hydroquinone results in decreased expression of JAG1 mRNA CTD PMID:22960397 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression ISO hydroquinone results in decreased expression of JCHAIN mRNA CTD PMID:29221148 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Jrk Jrk helix-turn-helix protein decreases expression ISO hydroquinone results in decreased expression of JRK mRNA CTD PMID:31256213 NCBI chr 7:106,590,662...106,595,345
Ensembl chr 7:106,589,484...106,596,371 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects localization
multiple interactions
increases phosphorylation		 ISO hydroquinone affects the localization of JUN protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein]; hydroquinone promotes the reaction [JUN protein binds to MIR122 promoter]; hydroquinone promotes the reaction [JUN protein binds to PPP2CA promoter]; JUN protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; JUN protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; JUN protein affects the reaction [hydroquinone results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein]		 CTD PMID:23288922 PMID:23791922 PMID:26807887 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kbtbd6 kelch repeat and BTB domain containing 6 decreases expression ISO hydroquinone results in decreased expression of KBTBD6 mRNA CTD PMID:31256213 NCBI chr15:54,848,285...54,850,042
Ensembl chr15:54,848,446...54,850,453 		JBrowse link
G Kbtbd7 kelch repeat and BTB domain containing 7 decreases expression ISO hydroquinone results in decreased expression of KBTBD7 mRNA CTD PMID:31256213 NCBI chr15:54,806,878...54,811,457
Ensembl chr15:54,806,873...54,811,687 		JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases expression ISO hydroquinone results in decreased expression of KCNJ15 mRNA CTD PMID:31256213 NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952 		JBrowse link
G Kdm6a lysine demethylase 6A decreases expression ISO hydroquinone results in decreased expression of KDM6A mRNA CTD PMID:31256213 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression ISO hydroquinone results in decreased expression of KEAP1 protein CTD PMID:23290930 PMID:36646296 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kics2 KICSTOR subunit 2 decreases expression ISO hydroquinone results in decreased expression of KICS2 mRNA CTD PMID:31256213 NCBI chr 7:57,284,213...57,299,070
Ensembl chr 7:57,284,192...57,297,486 		JBrowse link
G Kif18a kinesin family member 18A decreases expression ISO hydroquinone results in decreased expression of KIF18A mRNA CTD PMID:23416264 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582 		JBrowse link
G Kitlg KIT ligand increases expression ISO hydroquinone results in increased expression of KITLG mRNA CTD PMID:22960397 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Klf2 KLF transcription factor 2 increases expression ISO hydroquinone results in increased expression of KLF2 mRNA CTD PMID:31256213 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions ISO [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of KLF4 mRNA CTD PMID:37245849 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klf7 KLF transcription factor 7 increases expression ISO hydroquinone results in increased expression of KLF7 mRNA CTD PMID:31256213 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261 		JBrowse link
G Klhl31 kelch-like family member 31 decreases expression ISO hydroquinone results in decreased expression of KLHL31 mRNA CTD PMID:31256213 NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873 		JBrowse link
G Klk6 kallikrein related-peptidase 6 increases expression ISO hydroquinone results in increased expression of KLK6 mRNA CTD PMID:31256213 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121 		JBrowse link
G Klrg2 killer cell lectin like receptor G2 decreases expression ISO hydroquinone results in decreased expression of KLRG2 mRNA CTD PMID:31256213 NCBI chr 4:67,360,216...67,374,867
Ensembl chr 4:67,363,919...67,374,147 		JBrowse link
G Kmt2a lysine methyltransferase 2A decreases response to substance
multiple interactions		 ISO KMT2A mutant form results in decreased susceptibility to hydroquinone
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of APP mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of FABP4 mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of IL1B mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of KLF4 mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of LPL mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of PPARG mRNA		 CTD PMID:37245849 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions
increases expression
affects expression		 ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein
hydroquinone results in increased expression of KRAS protein
hydroquinone affects the expression of KRAS mRNA		 CTD PMID:27515134 PMID:28444915 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt13 keratin 13 decreases expression ISO hydroquinone results in decreased expression of KRT13 mRNA CTD PMID:31256213 NCBI chr10:85,051,887...85,056,099
Ensembl chr10:85,051,889...85,056,084 		JBrowse link
G Krt19 keratin 19 decreases expression ISO hydroquinone results in decreased expression of KRT19 mRNA CTD PMID:31256213 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt23 keratin 23 increases expression ISO hydroquinone results in increased expression of KRT23 mRNA CTD PMID:31256213 NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983 		JBrowse link
G Krt24 keratin 24 decreases expression ISO hydroquinone results in decreased expression of KRT24 mRNA CTD PMID:31256213 NCBI chr10:84,232,163...84,237,299
Ensembl chr10:84,232,164...84,237,299 		JBrowse link
G Krt78 keratin 78 increases expression ISO hydroquinone results in increased expression of KRT78 mRNA CTD PMID:31256213 NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021 		JBrowse link
G Krt80 keratin 80 increases expression ISO hydroquinone results in increased expression of KRT80 mRNA CTD PMID:31256213 NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508 		JBrowse link
G Lama4 laminin subunit alpha 4 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of LAMA4 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]		 CTD PMID:18055817 NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347 		JBrowse link
G Lasp1 LIM and SH3 protein 1 affects expression ISO hydroquinone affects the expression of LASP1 protein CTD PMID:20021034 NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO hydroquinone results in increased expression of LCN2 mRNA CTD PMID:31256213 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions
decreases expression		 ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]
hydroquinone results in decreased expression of LEF1 protein		 CTD PMID:28886972 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Lemd1 LEM domain containing 1 decreases expression ISO hydroquinone results in decreased expression of LEMD1 mRNA CTD PMID:31256213 NCBI chr13:43,631,705...43,697,765
Ensembl chr13:43,665,926...43,697,948 		JBrowse link
G Lgals9 galectin 9 increases expression ISO hydroquinone results in increased expression of LGALS9 mRNA CTD PMID:29221148 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lgalsl galectin-like increases expression ISO hydroquinone results in increased expression of LGALSL mRNA CTD PMID:31256213 NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980 		JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 decreases expression ISO hydroquinone results in decreased expression of LGR4 mRNA CTD PMID:31256213 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899 		JBrowse link
G Lipg lipase G, endothelial type increases expression ISO hydroquinone results in increased expression of LIPG mRNA CTD PMID:31256213 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Lmna lamin A/C affects expression ISO hydroquinone affects the expression of LMNA protein CTD PMID:17181942 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Loricrin loricrin cornified envelope precursor protein increases expression ISO hydroquinone results in increased expression of LORICRIN mRNA
hydroquinone results in increased expression of LORICRIN protein		 CTD PMID:25240866 PMID:31256213 NCBI chr 2:177,558,062...177,560,960
Ensembl chr 2:177,558,252...177,559,807 		JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of LPL mRNA CTD PMID:37245849 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrrc27 leucine rich repeat containing 27 decreases expression ISO hydroquinone results in decreased expression of LRRC27 mRNA CTD PMID:31256213 NCBI chr 1:194,004,967...194,035,087
Ensembl chr 1:194,005,182...194,035,084 		JBrowse link
G Lrrc71 leucine rich repeat containing 71 increases expression ISO hydroquinone results in increased expression of LRRC71 mRNA CTD PMID:29221148 NCBI chr 2:173,194,792...173,207,448
Ensembl chr 2:173,194,792...173,207,448 		JBrowse link
G Lrriq3 leucine-rich repeats and IQ motif containing 3 decreases expression ISO hydroquinone results in decreased expression of LRRIQ3 mRNA CTD PMID:31256213 NCBI chr 2:244,119,975...244,214,590
Ensembl chr 2:244,126,200...244,212,339 		JBrowse link
G Lss lanosterol synthase decreases expression ISO hydroquinone results in decreased expression of LSS mRNA CTD PMID:31256213 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO hydroquinone results in decreased expression of LY6E mRNA CTD PMID:31256213 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO hydroquinone results in increased expression of LY96 mRNA CTD PMID:31256213 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386 		JBrowse link
G Lypd5 Ly6/Plaur domain containing 5 increases expression ISO hydroquinone results in increased expression of LYPD5 mRNA CTD PMID:31256213 NCBI chr 1:79,929,818...79,941,791
Ensembl chr 1:79,935,240...79,941,039 		JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression ISO hydroquinone results in decreased expression of MACROH2A1 protein CTD PMID:35698848 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO hydroquinone results in increased expression of MAFF mRNA CTD PMID:31256213 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of MAGI1 mRNA; [hydroquinone co-treated with Hemin] affects the expression of MAGI1 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] CTD PMID:32198055 NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691 		JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO hydroquinone results in increased expression of MAP1B mRNA CTD PMID:31256213 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO Chloroquine inhibits the reaction [hydroquinone results in increased degradation of MAP1LC3A protein]; hydroquinone affects the localization of and results in increased degradation of MAP1LC3A protein CTD PMID:35302183 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation
multiple interactions		 ISO hydroquinone results in increased lipidation of MAP1LC3B protein
4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; ATF6 protein affects the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Chloroquine promotes the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Sirolimus promotes the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]		 CTD PMID:37148176 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein] CTD PMID:23288922 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map7d2 MAP7 domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MAP7D2 mRNA CTD PMID:31256213 NCBI chr  X:35,372,453...35,488,073
Ensembl chr  X:35,372,700...35,488,091 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased phosphorylation of MAPK1 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]
hydroquinone results in increased phosphorylation of MAPK1 protein		 CTD PMID:15129224 PMID:23288922 PMID:23290930 PMID:23791922 PMID:35561756 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases phosphorylation		 ISO Chloroquine inhibits the reaction [hydroquinone results in increased phosphorylation of MAPK14 protein] CTD PMID:35302183 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
decreases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased phosphorylation of MAPK3 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]
hydroquinone results in increased phosphorylation of MAPK3 protein		 CTD PMID:15129224 PMID:23288922 PMID:23290930 PMID:23791922 PMID:35561756 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 ISO hydroquinone results in increased phosphorylation of MAPK8 protein
hydroquinone results in decreased expression of and results in increased phosphorylation of MAPK8 protein		 CTD PMID:23791922 PMID:37148176 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Marchf3 membrane associated ring-CH-type finger 3 increases expression ISO hydroquinone results in increased expression of MARCHF3 mRNA CTD PMID:31256213 NCBI chr18:50,237,218...50,389,343
Ensembl chr18:50,237,230...50,389,150 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 decreases expression
multiple interactions
increases expression		 ISO hydroquinone results in decreased expression of MBD2 mRNA
PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]		 CTD PMID:22245671 PMID:30448557 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794 		JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 decreases expression ISO hydroquinone results in decreased expression of MBNL3 mRNA CTD PMID:31256213 NCBI chr  X:130,641,942...130,737,179
Ensembl chr  X:130,648,538...130,737,056 		JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 increases expression ISO hydroquinone results in increased expression of MBOAT2 mRNA CTD PMID:31256213 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485 		JBrowse link
G Mc1r melanocortin 1 receptor decreases expression ISO hydroquinone results in decreased expression of MC1R mRNA CTD PMID:23738040 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression
multiple interactions		 ISO hydroquinone results in increased expression of MCL1 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; [hydroquinone co-treated with WEHI-539] results in decreased expression of MCL1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein; PMAIP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]		 CTD PMID:35561756 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 increases expression ISO hydroquinone results in increased expression of MCTP1 mRNA CTD PMID:31256213 NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833 		JBrowse link
G Mctp2 multiple C2 and transmembrane domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MCTP2 mRNA CTD PMID:31256213 NCBI chr 1:125,769,932...126,002,886
Ensembl chr 1:125,771,233...126,002,928 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO hydroquinone results in increased expression of MDM2 mRNA CTD PMID:29221148 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mettl21a methyltransferase 21A, HSPA lysine decreases expression ISO hydroquinone results in decreased expression of METTL21A mRNA CTD PMID:31256213 NCBI chr 9:65,934,253...65,999,964
Ensembl chr 9:65,978,051...65,987,550 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO hydroquinone results in increased expression of MGST1 mRNA CTD PMID:15452088 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Mid1 midline 1 decreases expression ISO hydroquinone results in decreased expression of MID1 mRNA CTD PMID:31256213 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353 		JBrowse link
G Mir106b microRNA 106b decreases expression ISO hydroquinone results in decreased expression of MIR106B mRNA CTD PMID:28733890 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425 		JBrowse link
G Mir107 microRNA 107 decreases expression ISO hydroquinone results in decreased expression of MIR107 mRNA CTD PMID:28733890 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853 		JBrowse link
G Mir122 microRNA 122 multiple interactions
decreases expression		 ISO ATF2 protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; FOS protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; hydroquinone promotes the reaction [ATF2 protein binds to MIR122 promoter]; hydroquinone promotes the reaction [FOS protein binds to MIR122 promoter]; hydroquinone promotes the reaction [JUN protein binds to MIR122 promoter]; JUN protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; MIR122 mRNA affects the reaction [hydroquinone results in decreased expression of and results in increased secretion of TNF protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA] CTD PMID:23791922 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir126a microRNA 126a decreases expression ISO hydroquinone results in decreased expression of MIR126 mRNA CTD PMID:28733890 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir130a microRNA 130a decreases expression ISO hydroquinone results in decreased expression of MIR130A mRNA CTD PMID:28733890 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir146a microRNA 146a affects expression
multiple interactions		 ISO hydroquinone affects the expression of MIR146A mRNA
hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MIR146A mRNA]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]]		 CTD PMID:30090394 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir155 microRNA 155 multiple interactions
increases expression		 ISO Doxorubicin promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; trichostatin A promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA] CTD PMID:30448557 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir15b microRNA 15b decreases expression ISO hydroquinone results in decreased expression of MIR15B mRNA CTD PMID:28733890 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297 		JBrowse link
G Mir17 microRNA 17 decreases expression ISO hydroquinone results in decreased expression of MIR17 mRNA CTD PMID:28733890 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir185 microRNA 185 decreases expression ISO hydroquinone results in decreased expression of MIR185 mRNA CTD PMID:28733890 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir18a microRNA 18a decreases expression ISO hydroquinone results in decreased expression of MIR18A mRNA CTD PMID:28733890 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir19a microRNA 19a decreases expression ISO hydroquinone results in decreased expression of MIR19A mRNA CTD PMID:28733890 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir20a microRNA 20a decreases expression ISO hydroquinone results in decreased expression of MIR20A mRNA CTD PMID:28733890 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir20b microRNA 20b decreases expression ISO hydroquinone results in decreased expression of MIR20B mRNA CTD PMID:28733890 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282 		JBrowse link
G Mir223 microRNA 223 decreases expression ISO hydroquinone results in decreased expression of MIR223 mRNA CTD PMID:35698848 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir25 microRNA 25 decreases expression
multiple interactions		 ISO hydroquinone results in decreased expression of MIR25; hydroquinone results in decreased expression of MIR25 mRNA
[hydroquinone results in decreased expression of MIR25] which results in increased expression of NOX4 protein; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of MIR25]		 CTD PMID:28733890 PMID:35302183 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015 		JBrowse link
G Mir29a microRNA 29a decreases expression ISO hydroquinone results in decreased expression of MIR29A mRNA CTD PMID:28733890 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir342 microRNA 342 decreases expression ISO hydroquinone results in decreased expression of MIR342 mRNA CTD PMID:28733890 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367 		JBrowse link
G Mir451a microRNA 451a increases expression
multiple interactions		 ISO hydroquinone results in increased expression of MIR451A mRNA
hydroquinone affects the reaction [Hemin results in increased expression of MIR451A mRNA]		 CTD PMID:28733890 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591 		JBrowse link
G Mir486 microRNA 486 multiple interactions ISO hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; hydroquinone inhibits the reaction [Hemin results in increased expression of MIR486-1 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] CTD PMID:32198055
G Mir494 microRNA 494 decreases expression ISO hydroquinone results in decreased expression of MIR494 mRNA CTD PMID:28733890 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir93 microRNA 93 decreases expression ISO hydroquinone results in decreased expression of MIR93 mRNA CTD PMID:28733890 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Mirlet7g microRNA let-7g decreases expression ISO hydroquinone results in decreased expression of MIRLET7G mRNA CTD PMID:28733890 NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO hydroquinone results in increased expression of MMP1 mRNA CTD PMID:31256213 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions ISO [MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein] CTD PMID:18055817 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp15 matrix metallopeptidase 15 affects expression ISO hydroquinone affects the expression of MMP15 mRNA CTD PMID:15452088 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
multiple interactions		 ISO hydroquinone results in decreased activity of MMP2 protein
[MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]		 CTD PMID:16936130 PMID:18055817 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 affects expression
increases expression		 ISO hydroquinone affects the expression of MMP3 mRNA
hydroquinone results in increased expression of MMP3 mRNA		 CTD PMID:15452088 PMID:31256213 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
increases secretion		 ISO CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; hydroquinone inhibits the reaction [Dicumarol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]]; hydroquinone promotes the reaction [TNF protein results in increased secretion of MMP9 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; PARP1 protein inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]
hydroquinone results in increased expression of MMP9 mRNA; hydroquinone results in increased expression of MMP9 protein		 CTD PMID:17669387 PMID:26807887 PMID:27515134 PMID:33771647 PMID:33932074 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mob3b MOB kinase activator 3B decreases expression ISO hydroquinone results in decreased expression of MOB3B mRNA CTD PMID:31256213 NCBI chr 5:49,546,254...49,737,934
Ensembl chr 5:49,545,815...49,737,934 		JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor multiple interactions
decreases methylation
increases expression		 ISO [trichostatin A co-treated with Decitabine] promotes the reaction [hydroquinone results in increased expression of MPL mRNA]; Decitabine promotes the reaction [hydroquinone results in increased expression of MPL mRNA]
hydroquinone results in decreased methylation of MPL gene		 CTD PMID:22245671 NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases chemical synthesis
increases oxidation		 ISO [[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein; [[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone; [MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein]; [MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone; [MPO protein results in increased hydroxylation of Phenol] which results in increased chemical synthesis of hydroquinone; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]
MPO protein results in increased chemical synthesis of hydroquinone
MPO protein results in increased oxidation of hydroquinone		 CTD PMID:1666626 PMID:10994872 PMID:15777082 PMID:15935818 PMID:31248982 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mpzl3 myelin protein zero-like 3 increases expression ISO hydroquinone results in increased expression of MPZL3 mRNA CTD PMID:31256213 NCBI chr 8:45,360,475...45,380,662
Ensembl chr 8:45,349,054...45,380,662 		JBrowse link
G Mroh5 maestro heat-like repeat family member 5 decreases expression ISO hydroquinone results in decreased expression of MROH5 mRNA CTD PMID:29221148 NCBI chr 7:105,662,737...105,737,820
Ensembl chr 7:105,662,744...105,730,060 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression ISO hydroquinone results in increased expression of COX1 mRNA; hydroquinone results in increased expression of COX1 protein CTD PMID:23738040 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression		 EXP [[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of MT2A mRNA] CTD PMID:33188856 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 decreases expression ISO hydroquinone results in decreased expression of MTHFD1 mRNA CTD PMID:31256213 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions		 ISO hydroquinone results in decreased phosphorylation of MTOR protein
4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; ATF6 protein affects the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; Sirolimus promotes the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]		 CTD PMID:37148176 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mtus1 microtubule associated scaffold protein 1 decreases expression ISO hydroquinone results in decreased expression of MTUS1 mRNA CTD PMID:31256213 NCBI chr16:51,202,497...51,347,794
Ensembl chr16:51,253,562...51,347,793 		JBrowse link
G Mx1 MX dynamin like GTPase 1 decreases expression ISO hydroquinone results in decreased expression of MX1 mRNA CTD PMID:31256213 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507 		JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO hydroquinone results in decreased expression of MYB mRNA CTD PMID:22245671 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression		 ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein]
hydroquinone results in decreased expression of MYC mRNA		 CTD PMID:12749906 PMID:22245671 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor decreases expression ISO hydroquinone results in decreased expression of MYCL mRNA CTD PMID:31256213 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582 		JBrowse link
G Mylip myosin regulatory light chain interacting protein decreases expression ISO hydroquinone results in decreased expression of MYLIP mRNA CTD PMID:31256213 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295 		JBrowse link
G Myo1f myosin IF decreases expression ISO hydroquinone results in decreased expression of MYO1F mRNA CTD PMID:31256213 NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911 		JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 decreases expression ISO hydroquinone results in decreased expression of N4BP2L1 mRNA CTD PMID:31256213 NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO hydroquinone results in increased expression of NCF2 mRNA CTD PMID:31256213 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase decreases expression ISO hydroquinone results in decreased expression of NEDD4L mRNA CTD PMID:31256213 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137 		JBrowse link
G Nefh neurofilament heavy chain decreases expression ISO hydroquinone results in decreased expression of NEFH mRNA CTD PMID:31256213 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Neu3 neuraminidase 3 increases expression ISO hydroquinone results in increased expression of NEU3 mRNA CTD PMID:23776099 NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813 		JBrowse link
G Neurl1b neuralized E3 ubiquitin protein ligase 1B increases expression ISO hydroquinone results in increased expression of NEURL1B mRNA CTD PMID:29221148 NCBI chr10:16,754,002...16,785,049
Ensembl chr10:16,757,208...16,785,119 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 increases expression ISO hydroquinone results in increased expression of NFATC2 mRNA CTD PMID:31256213 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325 		JBrowse link
G Nfe2 nuclear factor, erythroid 2 multiple interactions ISO hydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] CTD PMID:21414390 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
decreases expression
increases activity		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and affects the localization of NFE2L2 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of NFE2L2 promoter]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; ferric chloride promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; hydroquinone affects the localization of and results in increased degradation of NFE2L2 protein; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; hydroquinone promotes the reaction [NFE2L2 protein binds to SRC protein]; hydroquinone results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]
hydroquinone results in increased expression of NFE2L2 mRNA; hydroquinone results in increased expression of NFE2L2 protein
hydroquinone results in decreased expression of NFE2L2 mRNA		 CTD PMID:21059386 PMID:21643505 PMID:23290930 PMID:28645578 PMID:31967339 More... NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases expression
increases expression		 ISO hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein]
hydroquinone results in decreased expression of NFKB1 mRNA
hydroquinone results in increased expression of NFKB1 protein		 CTD PMID:15894107 PMID:30090394 PMID:30448557 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 decreases expression ISO hydroquinone results in decreased expression of NFKB2 mRNA CTD PMID:30090394 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
affects phosphorylation		 ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
hydroquinone affects the phosphorylation of NFKBIA protein
hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]		 CTD PMID:20054000 PMID:23288922 PMID:30090394 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbib NFKB inhibitor beta decreases degradation ISO hydroquinone results in decreased degradation of NFKBIB protein CTD PMID:15894107 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862 		JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression ISO hydroquinone results in increased expression of NIBAN1 mRNA CTD PMID:31256213 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729 		JBrowse link
G Nid1 nidogen 1 decreases expression ISO hydroquinone results in decreased expression of NID1 mRNA CTD PMID:31256213 NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267 		JBrowse link
G Nipal3 NIPA-like domain containing 3 decreases expression ISO hydroquinone results in decreased expression of NIPAL3 mRNA CTD PMID:31256213 NCBI chr 5:147,687,310...147,725,838
Ensembl chr 5:147,685,288...147,726,351 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of NLRP3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]		 CTD PMID:36646296 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
decreases expression		 ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
hydroquinone results in increased expression of NOS2 mRNA
hydroquinone results in decreased expression of NOS2 mRNA; hydroquinone results in decreased expression of NOS2 protein		 CTD PMID:15831208 PMID:17464197 PMID:19148301 PMID:23290930 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
increases expression		 ISO [[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; [hydroquinone co-treated with WEHI-539] results in increased expression of NOX4 protein; [hydroquinone results in decreased expression of MIR25] which results in increased expression of NOX4 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in increased expression of NOX4 mRNA; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in increased expression of NOX4 protein; [WEHI-539 co-treated with hydroquinone] results in increased expression of NOX4 mRNA; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 protein]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 protein]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of CASP3 protein]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of PARP1 protein]; SIDT2 protein promotes the reaction [hydroquinone results in increased expression of NOX4 mRNA]
hydroquinone results in increased expression of NOX4 mRNA; hydroquinone results in increased expression of NOX4 protein		 CTD PMID:35302183 PMID:35561756 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
decreases response to substance		 ISO hydroquinone results in increased expression of NQO1 mRNA; hydroquinone results in increased expression of NQO1 protein
FAU protein affects the reaction [hydroquinone results in increased expression of and results in increased activity of NQO1 protein]; hydroquinone results in increased expression of and results in increased activity of NQO1 protein
NQO1 protein results in decreased susceptibility to hydroquinone
ferric chloride promotes the reaction [hydroquinone results in increased expression of NQO1 protein]; hydroquinone results in increased expression of and results in increased activity of NQO1 protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of NQO1 protein]		 CTD PMID:8652659 PMID:10368308 PMID:10393963 PMID:19525446 PMID:21059386 More... NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO hydroquinone results in decreased expression of NR4A2 mRNA CTD PMID:31256213 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Nras NRAS proto-oncogene, GTPase decreases expression ISO hydroquinone results in decreased expression of NRAS mRNA CTD PMID:26047893 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Nrbp2 nuclear receptor binding protein 2 increases expression ISO hydroquinone results in increased expression of NRBP2 mRNA CTD PMID:29221148 NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230 		JBrowse link
G Nudt16 nudix hydrolase 16 decreases expression ISO hydroquinone results in decreased expression of NUDT16 mRNA CTD PMID:31256213 NCBI chr 8:105,739,927...105,741,982
Ensembl chr 8:105,739,623...105,741,998 		JBrowse link
G Nwd2 NACHT and WD repeat domain containing 2 increases expression ISO hydroquinone results in increased expression of NWD2 mRNA CTD PMID:31256213 NCBI chr14:44,480,049...44,671,417
Ensembl chr14:44,482,287...44,670,299 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO hydroquinone results in decreased expression of OAS1 mRNA CTD PMID:31256213 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 decreases expression ISO hydroquinone results in decreased expression of OAS2 mRNA CTD PMID:31256213 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression ISO hydroquinone results in increased expression of OASL mRNA CTD PMID:29221148 PMID:31256213 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Ocln occludin multiple interactions EXP hydroquinone results in decreased degradation of and results in increased expression of OCLN protein CTD PMID:27587462 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Olah oleoyl-ACP hydrolase increases expression ISO hydroquinone results in increased expression of OLAH mRNA CTD PMID:31256213 NCBI chr17:74,877,651...74,902,517
Ensembl chr17:74,877,655...74,902,518 		JBrowse link
G Or2c1 olfactory receptor family 2 subfamily C member 1 decreases expression ISO hydroquinone results in decreased expression of OR2C1 mRNA CTD PMID:31256213 NCBI chr10:11,682,890...11,683,828
Ensembl chr10:11,681,001...11,692,105 		JBrowse link
G Ovol1 ovo like transcriptional repressor 1 increases expression ISO hydroquinone results in increased expression of OVOL1 mRNA CTD PMID:31256213 NCBI chr 1:202,855,261...202,868,858
Ensembl chr 1:202,855,265...202,866,831 		JBrowse link
G P2rx4 purinergic receptor P2X 4 increases expression ISO hydroquinone results in increased expression of P2RX4 mRNA CTD PMID:31256213 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253 		JBrowse link
G Pa2g4 proliferation-associated 2G4 affects expression ISO hydroquinone affects the expression of PA2G4 protein CTD PMID:17181942 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331 		JBrowse link
G Pabpc4l poly(A) binding protein, cytoplasmic 4-like decreases expression ISO hydroquinone results in decreased expression of PABPC4L mRNA CTD PMID:31256213 NCBI chr 2:129,807,755...129,809,745
Ensembl chr 2:129,807,755...129,809,745 		JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase decreases expression ISO hydroquinone results in decreased expression of PAICS mRNA CTD PMID:31256213 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635 		JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B decreases expression ISO hydroquinone results in decreased expression of PAIP2B mRNA CTD PMID:31256213 NCBI chr 4:116,292,001...116,323,387
Ensembl chr 4:116,292,020...116,323,379 		JBrowse link
G Palmd palmdelphin decreases expression ISO hydroquinone results in decreased expression of PALMD mRNA CTD PMID:31256213 NCBI chr 2:204,889,526...204,941,355
Ensembl chr 2:204,889,533...204,941,519 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
increases degradation
decreases expression
affects response to substance
increases expression
increases response to substance
affects expression
multiple interactions		 ISO hydroquinone results in increased cleavage of PARP1 protein
hydroquinone results in increased degradation of PARP1 protein
hydroquinone results in decreased expression of PARP1 protein
PARP1 protein affects the susceptibility to hydroquinone
hydroquinone results in increased expression of PARP1 protein
PARP1 protein results in increased susceptibility to hydroquinone
hydroquinone affects the expression of PARP1 protein
3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein]; [ABT-737 co-treated with hydroquinone] results in increased cleavage of PARP1 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein; [PARP1 protein co-treated with hydroquinone] results in increased expression of BCL2 protein; ABT-737 inhibits the reaction [hydroquinone affects the localization of PARP1 protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of PARP1 protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; hydroquinone results in increased expression of and affects the localization of PARP1 protein; hydroquinone results in increased expression of and results in increased cleavage of PARP1 protein; Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of PARP1 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of TJP2 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of AATF protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of BAX protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of CDKN2A protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of RB1 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of TP53 protein]; PARP1 protein inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]		 CTD PMID:19064679 PMID:23288922 PMID:26047893 PMID:26335980 PMID:26822515 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 decreases expression ISO hydroquinone results in decreased expression of PARP9 mRNA CTD PMID:31256213 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
G Pbx1 PBX homeobox 1 decreases expression ISO hydroquinone results in decreased expression of PBX1 mRNA CTD PMID:31256213 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO hydroquinone results in increased expression of PCK2 mRNA CTD PMID:31256213 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO hydroquinone results in decreased expression of PDCD4 mRNA CTD PMID:31256213 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Pde11a phosphodiesterase 11A decreases expression ISO hydroquinone results in decreased expression of PDE11A mRNA CTD PMID:31256213 NCBI chr 3:60,913,562...61,297,154
Ensembl chr 3:60,913,562...61,297,158 		JBrowse link
G Pde4b phosphodiesterase 4B decreases expression ISO hydroquinone results in decreased expression of PDE4B mRNA CTD PMID:31256213 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of PDGFRB mRNA CTD PMID:32198055 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases activity ISO hydroquinone metabolite results in decreased activity of PDPK1 protein; hydroquinone results in decreased activity of PDPK1 protein CTD PMID:20054000 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression ISO hydroquinone results in increased expression of PECAM1 protein CTD PMID:21664406 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Peg3 paternally expressed 3 decreases expression ISO hydroquinone results in decreased expression of PEG3 mRNA CTD PMID:31256213 NCBI chr 1:67,097,874...67,124,692
Ensembl chr 1:67,097,904...67,124,671 		JBrowse link
G Pgls 6-phosphogluconolactonase affects expression ISO hydroquinone affects the expression of PGLS protein CTD PMID:17181942 NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803 		JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 increases expression ISO hydroquinone results in increased expression of PGLYRP4 mRNA CTD PMID:31256213 NCBI chr 2:176,202,654...176,322,859
Ensembl chr 2:176,218,519...176,242,251 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO hydroquinone results in increased expression of PHLDA1 mRNA CTD PMID:31256213 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 decreases expression ISO hydroquinone results in decreased expression of PIK3C3 mRNA CTD PMID:31256213 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048 		JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 decreases expression ISO hydroquinone results in decreased expression of PIK3IP1 mRNA CTD PMID:31256213 NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein] CTD PMID:28836394 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO hydroquinone results in increased expression of PIM1 mRNA CTD PMID:31256213 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Pitx2 paired-like homeodomain 2 decreases expression ISO hydroquinone results in decreased expression of PITX2 mRNA CTD PMID:31256213 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha decreases expression ISO hydroquinone results in decreased expression of PKIA mRNA CTD PMID:31256213 NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282 		JBrowse link
G Pkp2 plakophilin 2 increases expression ISO hydroquinone results in increased expression of PKP2 mRNA CTD PMID:31256213 NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730 		JBrowse link
G Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 increases expression ISO hydroquinone results in increased expression of PLCXD1 mRNA CTD PMID:31256213 NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392 		JBrowse link
G Pld1 phospholipase D1 decreases expression ISO hydroquinone results in decreased expression of PLD1 mRNA CTD PMID:31256213 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692 		JBrowse link
G Pllp plasmolipin decreases expression ISO hydroquinone results in decreased expression of PLLP mRNA CTD PMID:31256213 NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; [hydroquinone co-treated with WEHI-539] results in increased expression of PMAIP1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 mRNA; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; mithramycin A inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 mRNA]; mithramycin A inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; PMAIP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein] CTD PMID:35561756 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pmfbp1 polyamine modulated factor 1 binding protein 1 increases expression ISO hydroquinone results in increased expression of PMFBP1 mRNA CTD PMID:31256213 NCBI chr19:37,458,126...37,507,880
Ensembl chr19:37,458,108...37,507,879 		JBrowse link
G Polh DNA polymerase eta multiple interactions
affects response to substance		 ISO POLH protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
POLH protein affects the susceptibility to hydroquinone		 CTD PMID:22981619 NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723 		JBrowse link
G Polr1b RNA polymerase I subunit B decreases expression ISO hydroquinone results in decreased expression of POLR1B mRNA CTD PMID:31256213 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO hydroquinone results in increased expression of PPARD mRNA CTD PMID:31256213 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of PPARG mRNA CTD PMID:37245849 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO hydroquinone results in increased expression of PPM1D mRNA CTD PMID:23416264 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO hydroquinone results in increased expression of PPP1R15A mRNA CTD PMID:31256213 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions
increases expression		 ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; Chloroquine inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; hydroquinone promotes the reaction [ATF2 protein binds to PPP2CA promoter]; hydroquinone promotes the reaction [CREB1 protein binds to PPP2CA promoter]; hydroquinone promotes the reaction [JUN protein binds to PPP2CA promoter]; JUN protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] CTD PMID:23288922 PMID:30567741 PMID:35302183 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha multiple interactions ISO PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] CTD PMID:30567741 NCBI chr13:102,931,264...102,975,661
Ensembl chr13:102,931,264...102,975,661 		JBrowse link
G Pptc7 protein phosphatase targeting COQ7 decreases expression ISO hydroquinone results in decreased expression of PPTC7 mRNA CTD PMID:31256213 NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339 		JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO hydroquinone results in increased expression of PRDM1 mRNA CTD PMID:31256213 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO hydroquinone results in increased expression of PRDX1 mRNA CTD PMID:15452088 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prkcg protein kinase C, gamma affects localization ISO hydroquinone affects the localization of PRKCG protein CTD PMID:23290930 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases expression ISO hydroquinone results in increased expression of PRKDC mRNA; hydroquinone results in increased expression of PRKDC protein CTD PMID:20036648 PMID:23940708 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prr9 proline rich 9 increases expression ISO hydroquinone results in increased expression of PRR9 mRNA CTD PMID:31256213 NCBI chr 2:177,599,483...177,600,849
Ensembl chr 2:177,599,483...177,600,849 		JBrowse link
G Prss3 serine protease 3 increases expression ISO hydroquinone results in increased expression of PRSS3 mRNA CTD PMID:31256213 NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562 		JBrowse link
G Psapl1 prosaposin-like 1 increases expression ISO hydroquinone results in increased expression of PSAPL1 mRNA CTD PMID:31256213 NCBI chr14:74,544,646...74,547,206
Ensembl chr14:74,544,646...74,547,206 		JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 decreases expression ISO hydroquinone results in decreased expression of PSRC1 mRNA CTD PMID:23416264 NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874 		JBrowse link
G Ptgr2 prostaglandin reductase 2 decreases expression ISO hydroquinone results in decreased expression of PTGR2 mRNA CTD PMID:31256213 NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO hydroquinone results in increased expression of PTGS2 mRNA CTD PMID:23290930 PMID:31256213 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 multiple interactions ISO [[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein CTD PMID:31248982 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions
increases expression		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of PYCARD protein] CTD PMID:36646296 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Pygb glycogen phosphorylase B increases expression ISO hydroquinone results in increased expression of PYGB mRNA CTD PMID:31256213 NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553 		JBrowse link
G Qpct glutaminyl-peptide cyclotransferase increases expression ISO hydroquinone results in increased expression of QPCT mRNA CTD PMID:31256213 NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711 		JBrowse link
G Rab30 RAB30, member RAS oncogene family decreases expression ISO hydroquinone results in decreased expression of RAB30 mRNA CTD PMID:31256213 NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181 		JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO hydroquinone results in increased expression of RAB3B mRNA CTD PMID:31256213 NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family decreases expression ISO hydroquinone results in decreased expression of RAB7B mRNA CTD PMID:31256213 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
G Rabgap1l RAB GTPase activating protein 1-like decreases expression ISO hydroquinone results in decreased expression of RABGAP1L mRNA CTD PMID:31256213 NCBI chr13:72,464,114...73,059,845
Ensembl chr13:72,468,110...73,059,984 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases expression ISO hydroquinone results in increased expression of RAF1 mRNA CTD PMID:22245671 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAP1A protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein] CTD PMID:32198055 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] CTD PMID:32198055 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein; hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] CTD PMID:32198055 NCBI chr13:42,637,513...42,703,024
Ensembl chr13:42,637,549...42,703,024 		JBrowse link
G Rb1 RB transcriptional corepressor 1 increases expression
decreases expression
multiple interactions		 ISO hydroquinone results in increased expression of RB protein
hydroquinone results in decreased expression of RB1 mRNA; hydroquinone results in decreased expression of RB1 protein
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of RB1 protein]; hydroquinone results in decreased expression of and results in increased phosphorylation of RB1 protein; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of RB1 protein]		 CTD PMID:26047893 PMID:30506647 PMID:33771647 PMID:33932074 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 increases expression ISO hydroquinone results in increased expression of RBCK1 mRNA CTD PMID:31256213 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005 		JBrowse link
G Rdh12 retinol dehydrogenase 12 increases expression ISO hydroquinone results in increased expression of RDH12 mRNA CTD PMID:31256213 NCBI chr 6:98,015,465...98,028,388
Ensembl chr 6:98,015,465...98,028,388 		JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs decreases expression ISO hydroquinone results in decreased expression of RECK mRNA CTD PMID:31256213 NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502 		JBrowse link
G Recql4 RecQ like helicase 4 increases expression ISO hydroquinone results in increased expression of RECQL4 mRNA CTD PMID:15452088 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
affects localization		 ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein]; hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
hydroquinone affects the localization of RELA protein
hydroquinone inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein]		 CTD PMID:15894107 PMID:16928326 PMID:20054000 PMID:23288922 PMID:30090394 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Reps1 RALBP1 associated Eps domain containing 1 decreases expression ISO hydroquinone results in decreased expression of REPS1 mRNA CTD PMID:31256213 NCBI chr 1:12,697,742...12,775,562
Ensembl chr 1:12,697,747...12,775,561 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 increases expression ISO hydroquinone results in increased expression of RFTN1 mRNA CTD PMID:31256213 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Rfx5 regulatory factor X5 decreases expression ISO hydroquinone results in decreased expression of RFX5 mRNA CTD PMID:31256213 NCBI chr 2:182,521,191...182,528,720
Ensembl chr 2:182,521,202...182,528,717 		JBrowse link
G Rgs17 regulator of G-protein signaling 17 increases expression ISO hydroquinone results in increased expression of RGS17 mRNA CTD PMID:31256213 NCBI chr 1:42,222,248...42,324,625
Ensembl chr 1:42,227,070...42,324,609 		JBrowse link
G Rhcg Rh family, C glycoprotein increases expression ISO hydroquinone results in increased expression of RHCG mRNA CTD PMID:31256213 NCBI chr 1:133,531,704...133,555,902
Ensembl chr 1:133,531,716...133,555,876 		JBrowse link
G Riok2 RIO kinase 2 decreases expression ISO hydroquinone results in decreased expression of RIOK2 mRNA CTD PMID:31256213 NCBI chr 1:58,103,132...58,119,397
Ensembl chr 1:58,103,084...58,120,512 		JBrowse link
G Rnase4 ribonuclease A family member 4 decreases expression ISO hydroquinone results in decreased expression of RNASE4 mRNA CTD PMID:31256213 NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117 		JBrowse link
G Rnasel ribonuclease L decreases expression ISO hydroquinone results in decreased expression of RNASEL mRNA CTD PMID:31256213 NCBI chr13:65,894,990...65,910,354
Ensembl chr13:65,901,459...65,908,704 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 decreases expression ISO hydroquinone results in decreased expression of ROR1 mRNA CTD PMID:31256213 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 increases expression ISO hydroquinone results in increased expression of RPS6KA2 mRNA CTD PMID:31256213 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739 		JBrowse link
G Rptn repetin increases expression ISO hydroquinone results in increased expression of RPTN mRNA CTD PMID:25240866 PMID:31256213 NCBI chr 2:179,061,768...179,066,056
Ensembl chr 2:179,060,017...179,065,910 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO hydroquinone results in increased expression of RRAD mRNA CTD PMID:31256213 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417 		JBrowse link
G Rrp12 ribosomal RNA processing 12 decreases expression ISO hydroquinone results in decreased expression of RRP12 mRNA CTD PMID:31256213 NCBI chr 1:240,672,378...240,705,992
Ensembl chr 1:240,672,382...240,706,018 		JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO hydroquinone results in increased expression of RUNX2 mRNA CTD PMID:22960397 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G S100a7a S100 calcium binding protein A7A decreases expression ISO hydroquinone results in decreased expression of S100A7A mRNA CTD PMID:25240866 NCBI chr 2:176,151,405...176,155,846
Ensembl chr 2:176,151,288...176,156,441 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO hydroquinone results in increased expression of S100A9 mRNA CTD PMID:25240866 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G S100b S100 calcium binding protein B multiple interactions ISO hydroquinone results in increased expression of and results in increased secretion of S100B protein CTD PMID:24451020 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Satb1 SATB homeobox 1 decreases expression ISO hydroquinone results in decreased expression of SATB1 mRNA CTD PMID:31256213 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251 		JBrowse link
G Sbk1 SH3 domain binding kinase 1 decreases expression ISO hydroquinone results in decreased expression of SBK1 mRNA CTD PMID:31256213 NCBI chr 1:180,807,092...180,851,910
Ensembl chr 1:180,807,099...180,851,885 		JBrowse link
G Scara3 scavenger receptor class A, member 3 decreases expression ISO hydroquinone results in decreased expression of SCARA3 mRNA CTD PMID:31256213 NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894 		JBrowse link
G Scfd2 sec1 family domain containing 2 decreases expression ISO hydroquinone results in decreased expression of SCFD2 mRNA CTD PMID:31256213 NCBI chr14:33,683,348...34,008,232
Ensembl chr14:33,683,273...34,008,213 		JBrowse link
G Scg5 secretogranin V increases expression ISO hydroquinone results in increased expression of SCG5 mRNA CTD PMID:31256213 NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463 		JBrowse link
G Sdr9c7 short chain dehydrogenase/reductase family 9C, member 7 increases expression ISO hydroquinone results in increased expression of SDR9C7 mRNA CTD PMID:31256213 NCBI chr 7:63,703,788...63,720,325
Ensembl chr 7:63,707,071...63,721,480 		JBrowse link
G Sec24d SEC24 homolog D, COPII coat complex component increases expression ISO hydroquinone results in increased expression of SEC24D mRNA CTD PMID:31256213 NCBI chr 2:211,418,557...211,526,588
Ensembl chr 2:211,418,623...211,526,587 		JBrowse link
G Selenop selenoprotein P decreases expression ISO hydroquinone results in decreased expression of SELENOP mRNA CTD PMID:31256213 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852 		JBrowse link
G Selp selectin P increases expression ISO hydroquinone results in increased expression of SELP mRNA; hydroquinone results in increased expression of SELP protein CTD PMID:34718823 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Septin6 septin 6 decreases expression ISO hydroquinone results in decreased expression of SEPTIN6 mRNA CTD PMID:31256213 NCBI chr  X:116,153,255...116,230,334
Ensembl chr  X:116,153,255...116,230,115 		JBrowse link
G Serpina12 serpin family A member 12 increases expression ISO hydroquinone results in increased expression of SERPINA12 mRNA CTD PMID:31256213 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271 		JBrowse link
G Serpinb9 serpin family B member 9 increases expression ISO hydroquinone results in increased expression of SERPINB9 mRNA CTD PMID:31256213 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230 		JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO hydroquinone results in increased expression of SERPINE2 mRNA CTD PMID:31256213 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Sesn1 sestrin 1 increases expression ISO hydroquinone results in increased expression of SESN1 mRNA CTD PMID:23416264 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sesn2 sestrin 2 increases expression ISO hydroquinone results in increased expression of SESN2 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sesn3 sestrin 3 decreases expression ISO hydroquinone results in decreased expression of SESN3 mRNA CTD PMID:31256213 NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842 		JBrowse link
G Sfn stratifin affects methylation
increases expression
multiple interactions		 ISO hydroquinone affects the methylation of SFN promoter
hydroquinone results in increased expression of SFN mRNA
[hydroquinone affects the methylation of SFN promoter] which results in decreased abundance of 5-Methylcytosine; [hydroquinone affects the methylation of SFN promoter] which results in increased abundance of 5-hydroxymethylcytosine; TET1 protein affects the reaction [hydroquinone results in increased expression of SFN mRNA]		 CTD PMID:23940045 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 decreases expression ISO hydroquinone results in decreased expression of SFRP1 mRNA CTD PMID:31256213 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sfta2 surfactant associated 2 increases expression ISO hydroquinone results in increased expression of SFTA2 mRNA CTD PMID:31256213 NCBI chr20:3,093,569...3,094,299
Ensembl chr20:3,093,565...3,094,299 		JBrowse link
G Sgcg sarcoglycan, gamma increases expression ISO hydroquinone results in increased expression of SGCG mRNA CTD PMID:31256213 NCBI chr15:35,388,836...35,435,072
Ensembl chr15:35,386,534...35,435,148 		JBrowse link
G Sh3bgr SH3 domain binding glutamate-rich protein increases expression ISO hydroquinone results in increased expression of SH3BGR mRNA CTD PMID:31256213 NCBI chr11:35,503,663...35,527,853
Ensembl chr11:35,503,725...35,527,853 		JBrowse link
G Sh3bp2 SH3-domain binding protein 2 increases expression ISO hydroquinone results in increased expression of SH3BP2 mRNA CTD PMID:31256213 NCBI chr14:76,176,097...76,213,300
Ensembl chr14:76,176,101...76,213,251 		JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 increases expression ISO hydroquinone results in increased expression of SH3KBP1 mRNA CTD PMID:31256213 NCBI chr  X:34,877,862...35,223,013
Ensembl chr  X:34,877,866...35,222,747 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 decreases expression ISO hydroquinone results in decreased expression of SH3RF2 mRNA CTD PMID:31256213 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 increases expression ISO hydroquinone results in increased expression of SH3TC1 mRNA CTD PMID:31256213 NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995 		JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 increases expression ISO hydroquinone results in increased expression of SIAH1 mRNA CTD PMID:31256213 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 increases expression
multiple interactions		 ISO hydroquinone results in increased expression of SIDT2 protein
[[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of MIR25]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; SIDT2 protein promotes the reaction [hydroquinone results in increased expression of NOX4 mRNA]		 CTD PMID:35302183 NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700 		JBrowse link
G Sik1 salt-inducible kinase 1 decreases expression ISO hydroquinone results in decreased expression of SIK1 mRNA CTD PMID:31256213 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions
affects expression
affects response to substance		 ISO [SIRT1 protein affects the susceptibility to hydroquinone] which affects the expression of H2AX protein; SIRT1 protein affects the reaction [hydroquinone results in increased expression of CDKN1A protein]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA]
hydroquinone affects the expression of SIRT1 mRNA; hydroquinone affects the expression of SIRT1 protein		 CTD PMID:27515134 PMID:28263894 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt3 sirtuin 3 decreases expression
multiple interactions
increases degradation		 ISO hydroquinone results in decreased expression of SIRT3 mRNA; hydroquinone results in decreased expression of SIRT3 protein
[[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in increased degradation of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; SIRT3 protein inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]		 CTD PMID:35302183 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Slc16a6 solute carrier family 16, member 6 decreases expression ISO hydroquinone results in decreased expression of SLC16A6 mRNA CTD PMID:31256213 NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression EXP hydroquinone results in increased expression of SLC2A1 protein CTD PMID:27587462 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a12 solute carrier family 2 member 12 decreases expression ISO hydroquinone results in decreased expression of SLC2A12 mRNA CTD PMID:31256213 NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971 		JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression ISO hydroquinone results in decreased expression of SLC2A5 mRNA CTD PMID:31256213 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106 		JBrowse link
G Slc5a1 solute carrier family 5 member 1 increases expression ISO hydroquinone results in increased expression of SLC5A1 mRNA CTD PMID:31256213 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 decreases expression ISO hydroquinone results in decreased expression of SLC5A3 mRNA CTD PMID:31256213 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO hydroquinone results in increased expression of SLC7A11 mRNA CTD PMID:31256213 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Smim5 small integral membrane protein 5 increases expression ISO hydroquinone results in increased expression of SMIM5 mRNA CTD PMID:31256213 NCBI chr10:101,134,033...101,139,814
Ensembl chr10:101,134,033...101,139,813 		JBrowse link
G Snx24 sorting nexin 24 increases expression ISO hydroquinone results in increased expression of SNX24 mRNA CTD PMID:31256213 NCBI chr18:46,670,987...46,826,070
Ensembl chr18:46,671,443...46,826,068 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity
multiple interactions
increases expression
decreases expression		 ISO hydroquinone results in decreased activity of SOD1 protein
S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of SOD1 protein]
hydroquinone results in decreased expression of SOD1 mRNA		 CTD PMID:15816534 PMID:32141582 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 decreases activity
multiple interactions
increases expression
decreases expression		 ISO hydroquinone results in decreased activity of SOD2 protein
S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of SOD2 protein]
hydroquinone results in decreased expression of SOD2 mRNA		 CTD PMID:15816534 PMID:32141582 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox11 SRY-box transcription factor 11 decreases expression ISO hydroquinone results in decreased expression of SOX11 mRNA CTD PMID:31256213 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO hydroquinone results in decreased expression of SOX2 mRNA CTD PMID:31256213 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox4 SRY-box transcription factor 4 decreases expression ISO hydroquinone results in decreased expression of SOX4 mRNA CTD PMID:31256213 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; [hydroquinone co-treated with WEHI-539] results in increased expression of SP1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein] CTD PMID:35561756 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Sp110 SP110 nuclear body protein decreases expression ISO hydroquinone results in decreased expression of SP110 mRNA CTD PMID:31256213 NCBI chr 9:86,200,503...86,225,355
Ensembl chr 9:86,200,503...86,222,670 		JBrowse link
G Spi1 Spi-1 proto-oncogene increases phosphorylation ISO hydroquinone results in increased phosphorylation of SPI1 protein CTD PMID:16642264 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression ISO hydroquinone results in increased expression of SPINK1 mRNA CTD PMID:31256213 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
G Spink4 serine peptidase inhibitor, Kazal type 4 decreases expression ISO hydroquinone results in decreased expression of SPINK4 mRNA CTD PMID:31256213 NCBI chr 5:56,043,936...56,064,841
Ensembl chr 5:55,981,624...56,064,795 		JBrowse link
G Spink6 serine peptidase inhibitor, Kazal type 6 decreases expression ISO hydroquinone results in decreased expression of SPINK6 mRNA CTD PMID:31256213 NCBI chr18:36,397,833...36,410,010
Ensembl chr18:36,397,910...36,409,819 		JBrowse link
G Sprr2b small proline rich protein 2B increases expression ISO hydroquinone results in increased expression of SPRR2B mRNA CTD PMID:25240866 PMID:31256213 NCBI chr 2:177,852,824...177,853,096
Ensembl chr 2:177,852,824...177,853,096 		JBrowse link
G Sprr3 small proline-rich protein 3 increases expression ISO hydroquinone results in increased expression of SPRR3 mRNA CTD PMID:25240866 PMID:31256213 NCBI chr 2:178,027,743...178,028,501
Ensembl chr 2:178,027,425...178,029,891 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 increases expression ISO hydroquinone results in increased expression of SPRY4 mRNA CTD PMID:31256213 NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression
multiple interactions		 ISO hydroquinone results in decreased expression of SQSTM1 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased expression of SQSTM1 protein]; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased expression of SQSTM1 protein; Chloroquine inhibits the reaction [hydroquinone results in increased degradation of SQSTM1 protein]; hydroquinone results in increased degradation of and results in decreased expression of SQSTM1 protein		 CTD PMID:28263894 PMID:35302183 PMID:35561756 PMID:37148176 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases phosphorylation		 ISO AG 1879 inhibits the reaction [hydroquinone results in increased phosphorylation of SRC protein]
hydroquinone promotes the reaction [NFE2L2 protein binds to SRC protein]		 CTD PMID:23290930 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression ISO hydroquinone results in decreased expression of ST3GAL3 mRNA CTD PMID:23776099 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810 		JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 decreases expression ISO hydroquinone results in decreased expression of ST6GALNAC5 mRNA CTD PMID:31256213 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO hydroquinone results in decreased expression of STAT1 mRNA CTD PMID:31256213 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO hydroquinone results in increased expression of STC2 mRNA CTD PMID:23416264 PMID:31256213 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Stk40 serine/threonine kinase 40 increases expression ISO hydroquinone results in increased expression of STK40 mRNA CTD PMID:31256213 NCBI chr 5:138,380,049...138,417,802
Ensembl chr 5:138,381,159...138,417,796 		JBrowse link
G Stxbp6 syntaxin binding protein 6 decreases expression ISO hydroquinone results in decreased expression of STXBP6 mRNA CTD PMID:31256213 NCBI chr 6:61,920,756...62,157,405
Ensembl chr 6:61,920,756...62,158,024 		JBrowse link
G Sybu syntabulin increases expression ISO hydroquinone results in increased expression of SYBU mRNA CTD PMID:31256213 NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828 		JBrowse link
G Sycp2l synaptonemal complex protein 2-like decreases expression ISO hydroquinone results in decreased expression of SYCP2L mRNA CTD PMID:31256213 NCBI chr17:23,589,217...23,645,273
Ensembl chr17:23,592,899...23,648,306 		JBrowse link
G Taf3 TATA-box binding protein associated factor 3 decreases expression ISO hydroquinone results in decreased expression of TAF3 mRNA CTD PMID:31256213 NCBI chr17:68,455,389...68,608,367
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Taldo1 transaldolase 1 affects expression ISO hydroquinone affects the expression of TALDO1 protein CTD PMID:20021034 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974 		JBrowse link
G Tardbp TAR DNA binding protein affects expression ISO hydroquinone affects the expression of TARDBP protein CTD PMID:20021034 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055 		JBrowse link
G Tceanc transcription elongation factor A N-terminal and central domain containing decreases expression ISO hydroquinone results in decreased expression of TCEANC mRNA CTD PMID:31256213 NCBI chr  X:27,952,539...27,961,038
Ensembl chr  X:27,952,457...27,960,940 		JBrowse link
G Tcf4 transcription factor 4 decreases expression ISO hydroquinone results in decreased expression of TCF4 mRNA CTD PMID:31256213 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425 		JBrowse link
G Tenm4 teneurin transmembrane protein 4 decreases expression ISO hydroquinone results in decreased expression of TENM4 mRNA CTD PMID:31256213 NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 decreases expression
multiple interactions		 EXP
ISO		 hydroquinone results in decreased expression of TET1 mRNA
hydroquinone results in increased expression of and results in increased activity of TET1 protein; TET1 protein affects the reaction [hydroquinone results in increased expression of GCLC mRNA]; TET1 protein affects the reaction [hydroquinone results in increased expression of SFN mRNA]
[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TET1 mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TET1 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of TET1 mRNA]		 CTD PMID:23940045 PMID:33188856 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052 		JBrowse link
G Tfrc transferrin receptor multiple interactions
decreases expression		 ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFRC protein]; hydroquinone promotes the reaction [Hemin results in decreased expression of TFRC mRNA]
hydroquinone results in decreased expression of TFRC protein		 CTD PMID:12749906 PMID:21414390 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 decreases expression ISO hydroquinone results in decreased expression of TGFBR3 mRNA CTD PMID:31256213 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Thnsl1 threonine synthase-like 1 decreases expression ISO hydroquinone results in decreased expression of THNSL1 mRNA CTD PMID:31256213 NCBI chr17:83,714,794...83,722,190
Ensembl chr17:83,714,738...83,723,805 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 multiple interactions ISO hydroquinone inhibits the reaction [TICAM1 protein results in increased phosphorylation of IRF3 protein] CTD PMID:28883758 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions
decreases expression		 ISO
EXP		 [MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]
hydroquinone results in decreased expression of TIMP2 mRNA
[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP2 mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP2 mRNA]		 CTD PMID:18055817 PMID:33188856 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression
multiple interactions		 EXP hydroquinone results in decreased expression of TIMP3 mRNA
[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP3 mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP3 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of TIMP3 mRNA]		 CTD PMID:33188856 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO hydroquinone results in increased expression of TIPARP mRNA CTD PMID:23416264 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP hydroquinone results in decreased degradation of and results in increased expression of TJP1 protein CTD PMID:27587462 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tjp2 tight junction protein 2 multiple interactions
decreases expression		 ISO PARP1 protein affects the reaction [hydroquinone results in decreased expression of TJP2 mRNA] CTD PMID:28983606 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
G Tk2 thymidine kinase 2 decreases expression ISO hydroquinone results in decreased expression of TK2 mRNA CTD PMID:31256213 NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924 		JBrowse link
G Tkt transketolase increases expression ISO hydroquinone results in increased expression of TKT mRNA CTD PMID:31256213 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
G Tlr3 toll-like receptor 3 decreases expression ISO hydroquinone results in decreased expression of TLR3 mRNA CTD PMID:31256213 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:20054000 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmc6 transmembrane channel like 6 decreases expression ISO hydroquinone results in decreased expression of TMC6 mRNA CTD PMID:31256213 NCBI chr10:102,982,059...102,999,509
Ensembl chr10:102,971,229...102,998,960 		JBrowse link
G Tmem106a transmembrane protein 106A decreases expression ISO hydroquinone results in decreased expression of TMEM106A mRNA CTD PMID:31256213 NCBI chr10:86,506,908...86,515,915
Ensembl chr10:86,506,936...86,515,892 		JBrowse link
G Tmem125 transmembrane protein 125 increases expression ISO hydroquinone results in increased expression of TMEM125 mRNA CTD PMID:31256213 NCBI chr 5:132,063,162...132,064,566
Ensembl chr 5:132,059,554...132,079,297
Ensembl chr 5:132,059,554...132,079,297 		JBrowse link
G Tmem19 transmembrane protein 19 decreases expression ISO hydroquinone results in decreased expression of TMEM19 mRNA CTD PMID:31256213 NCBI chr 7:50,958,884...50,985,601
Ensembl chr 7:50,958,888...50,986,809 		JBrowse link
G Tmem200a transmembrane protein 200A increases expression ISO hydroquinone results in increased expression of TMEM200A mRNA CTD PMID:31256213 NCBI chr 1:19,323,646...19,408,324
Ensembl chr 1:19,323,829...19,406,453 		JBrowse link
G Tmem45b transmembrane protein 45b increases expression ISO hydroquinone results in increased expression of TMEM45B mRNA CTD PMID:31256213 NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453 		JBrowse link
G Tmem97 transmembrane protein 97 decreases expression ISO hydroquinone results in decreased expression of TMEM97 mRNA CTD PMID:31256213 NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730 		JBrowse link
G Tmt1a thiol methyltransferase 1A decreases expression ISO hydroquinone results in decreased expression of TMT1A mRNA CTD PMID:31256213 NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154 		JBrowse link
G Tmt1b thiol methyltransferase 1B decreases expression ISO hydroquinone results in decreased expression of TMT1B mRNA CTD PMID:29221148 NCBI chr 7:1,388,876...1,391,526
Ensembl chr 7:1,388,879...1,391,526 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases activity
increases secretion		 ISO
EXP		 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of TNF protein]; [hydroquinone co-treated with TNF protein] results in increased secretion of CXCL8 protein; [hydroquinone co-treated with TNF protein] results in increased secretion of IL6 protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of TNF protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; ADAM17 protein affects the reaction [hydroquinone results in increased secretion of TNF protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [hydroquinone results in increased expression of TNF protein]; Chloroquine inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]; CREB1 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; hydroquinone inhibits the reaction [Dicumarol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]]; hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein]; hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; hydroquinone promotes the reaction [TNF protein results in increased secretion of MMP9 protein]; hydroquinone results in decreased expression of and results in increased secretion of TNF protein; hydroquinone results in increased expression of and results in increased secretion of TNF protein; hydroquinone results in increased expression of and results in increased stability of TNF mRNA; JUN protein affects the reaction [hydroquinone results in increased expression of TNF protein]; MIR122 mRNA affects the reaction [hydroquinone results in decreased expression of and results in increased secretion of TNF protein]; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [hydroquinone results in decreased expression of and results in increased secretion of TNF protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]; Okadaic Acid inhibits the reaction [hydroquinone results in increased expression of TNF protein]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]; SIRT3 protein inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]; ZFP36 protein inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]; ZFP36 protein inhibits the reaction [hydroquinone results in increased expression of TNF protein]
hydroquinone results in increased expression of TNF mRNA; hydroquinone results in increased expression of TNF protein
hydroquinone results in decreased activity of TNF protein
[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased expression of and results in increased secretion of TNF protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride; Chlorpromazine inhibits the reaction [[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride]; Chlorpromazine inhibits the reaction [hydroquinone results in increased expression of TNF protein]; Cromolyn Sodium inhibits the reaction [[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; hydroquinone metabolite inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]		 CTD PMID:9571986 PMID:10890505 PMID:17118622 PMID:17464197 PMID:17669387 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO hydroquinone results in increased expression of TNFAIP2 mRNA CTD PMID:31256213 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression ISO hydroquinone results in increased expression of TNFRSF12A mRNA CTD PMID:31256213 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions
increases expression		 ISO alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of TNFRSF1A protein] CTD PMID:34200499 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression
multiple interactions		 ISO hydroquinone results in increased expression of TNFRSF1B protein
hydroquinone results in increased expression of TNFRSF1B mRNA
alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of TNFRSF1B protein]		 CTD PMID:22414385 PMID:34200499 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 decreases expression ISO hydroquinone results in decreased expression of TNFRSF25 mRNA CTD PMID:15452088 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO hydroquinone results in increased expression of TNFRSF9 mRNA CTD PMID:22723965 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO hydroquinone results in decreased expression of TNFSF11 mRNA CTD PMID:31256213 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnfsf12 TNF superfamily member 12 decreases expression ISO hydroquinone results in decreased expression of TNFSF12 mRNA CTD PMID:15452088 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase increases expression ISO hydroquinone results in increased expression of TNIK mRNA CTD PMID:31256213 NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750 		JBrowse link
G Top2a DNA topoisomerase II alpha affects activity
decreases activity
multiple interactions		 ISO hydroquinone affects the activity of TOP2A protein
hydroquinone results in decreased activity of TOP2A protein
[MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein]		 CTD PMID:9118903 PMID:11468185 PMID:15211611 PMID:15833037 PMID:15935818 More... NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 increases expression
affects expression
decreases expression
multiple interactions		 ISO hydroquinone results in increased expression of TP53 protein; hydroquinone results in increased expression of TRP53 protein
hydroquinone affects the expression of TP53 protein
hydroquinone results in decreased expression of TP53 mRNA; hydroquinone results in decreased expression of TP53 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of TP53 protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of TP53 protein]; [ABT-737 co-treated with hydroquinone] results in increased expression of TRP53 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of TP53 protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of TP53 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of TP53 protein]; WRN protein affects the reaction [hydroquinone results in increased acetylation of TP53 protein]; WRN protein affects the reaction [hydroquinone results in increased expression of TP53 protein]		 CTD PMID:17875398 PMID:23940708 PMID:26047893 PMID:27515134 PMID:28444915 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO hydroquinone results in increased expression of TP53INP1 mRNA CTD PMID:23416264 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968 		JBrowse link
G Tprg1 tumor protein p63 regulated 1 increases expression ISO hydroquinone results in increased expression of TPRG1 mRNA CTD PMID:31256213 NCBI chr11:75,322,470...75,449,907
Ensembl chr11:75,322,470...75,449,907 		JBrowse link
G Tradd TNFRSF1A-associated via death domain increases expression ISO hydroquinone results in increased expression of TRADD mRNA CTD PMID:15452088 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Traf4 Tnf receptor associated factor 4 decreases expression ISO hydroquinone results in decreased expression of TRAF4 mRNA CTD PMID:15452088 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284 		JBrowse link
G Traf6 TNF receptor associated factor 6 decreases expression
multiple interactions		 ISO hydroquinone results in decreased expression of TRAF6 mRNA; hydroquinone results in decreased expression of TRAF6 protein
hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 mRNA]; hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]]		 CTD PMID:30090394 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO hydroquinone results in increased expression of TRIB1 mRNA CTD PMID:31256213 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO hydroquinone results in increased expression of TRIB3 mRNA CTD PMID:31256213 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Trim59 tripartite motif-containing 59 decreases expression ISO hydroquinone results in decreased expression of TRIM59 mRNA CTD PMID:23416264 NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031 		JBrowse link
G Trim62 tripartite motif-containing 62 increases expression ISO hydroquinone results in increased expression of TRIM62 mRNA CTD PMID:31256213 NCBI chr 5:141,230,830...141,260,629
Ensembl chr 5:141,231,523...141,259,915 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity
multiple interactions		 ISO hydroquinone results in increased activity of TRPA1 protein
[hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium; Dithiothreitol inhibits the reaction [[hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium]; Dithiothreitol inhibits the reaction [hydroquinone results in increased activity of TRPA1 protein]; mustard oil promotes the reaction [[hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium]; mustard oil promotes the reaction [hydroquinone results in increased activity of TRPA1 protein]		 CTD PMID:21591660 PMID:28790335 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Tshz1 teashirt zinc finger homeobox 1 decreases expression ISO hydroquinone results in decreased expression of TSHZ1 mRNA CTD PMID:31256213 NCBI chr18:77,376,399...77,452,815
Ensembl chr18:77,377,394...77,453,509 		JBrowse link
G Tslp thymic stromal lymphopoietin increases expression ISO hydroquinone results in increased expression of TSLP mRNA CTD PMID:31256213 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Ttc14 tetratricopeptide repeat domain 14 decreases expression ISO hydroquinone results in decreased expression of TTC14 mRNA CTD PMID:31256213 NCBI chr 2:116,653,543...116,665,072
Ensembl chr 2:116,653,595...116,664,158 		JBrowse link
G Txn1 thioredoxin 1 increases expression ISO hydroquinone results in increased expression of TXN mRNA CTD PMID:15452088 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO hydroquinone results in increased expression of TXNRD1 mRNA CTD PMID:15452088 PMID:31256213 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Tyr tyrosinase increases expression ISO hydroquinone results in increased expression of TYR mRNA; hydroquinone results in increased expression of TYR protein CTD PMID:23738040 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase increases expression ISO hydroquinone results in increased expression of UGCG mRNA CTD PMID:31256213 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases metabolic processing EXP UGT1A6 protein results in increased metabolism of hydroquinone CTD PMID:9118891 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO hydroquinone results in decreased expression of UHRF1 protein CTD PMID:27979589 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631 		JBrowse link
G Unc5b unc-5 netrin receptor B increases expression ISO hydroquinone results in increased expression of UNC5B mRNA CTD PMID:31256213 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Upp1 uridine phosphorylase 1 increases expression ISO hydroquinone results in increased expression of UPP1 mRNA CTD PMID:31256213 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462 		JBrowse link
G Usp51 ubiquitin specific peptidase 51 decreases expression ISO hydroquinone results in decreased expression of USP51 mRNA CTD PMID:31256213 NCBI chr  X:18,374,940...18,381,472
Ensembl chr  X:18,376,930...18,379,888 		JBrowse link
G Vapa VAMP associated protein A decreases expression ISO hydroquinone results in decreased expression of VAPA mRNA CTD PMID:31256213 NCBI chr 9:105,177,904...105,208,400
Ensembl chr 9:105,177,907...105,207,847 		JBrowse link
G Vasn vasorin increases expression ISO hydroquinone results in increased expression of VASN mRNA CTD PMID:31256213 NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
increases secretion		 ISO hydroquinone results in increased expression of VEGFA mRNA
hydroquinone results in increased secretion of VEGFA protein		 CTD PMID:23559866 PMID:29124153 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO hydroquinone results in increased expression of VLDLR mRNA CTD PMID:31256213 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
G Vsig10l V-set and immunoglobulin domain containing 10 like increases expression ISO hydroquinone results in increased expression of VSIG10L mRNA CTD PMID:31256213 NCBI chr 1:93,871,487...93,880,157
Ensembl chr 1:93,851,774...93,879,566 		JBrowse link
G Vsnl1 visinin-like 1 decreases expression ISO hydroquinone results in decreased expression of VSNL1 mRNA CTD PMID:31256213 NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479 		JBrowse link
G Vwde von Willebrand factor D and EGF domains decreases expression ISO hydroquinone results in decreased expression of VWDE mRNA CTD PMID:31256213 NCBI chr 4:41,453,573...41,525,421
Ensembl chr 4:41,455,281...41,533,374 		JBrowse link
G Wfdc12 WAP four-disulfide core domain 12 increases expression ISO hydroquinone results in increased expression of WFDC12 mRNA CTD PMID:31256213 NCBI chr 3:152,861,461...152,862,784
Ensembl chr 3:152,862,341...152,862,690 		JBrowse link
G Wnt4 Wnt family member 4 decreases expression ISO hydroquinone results in decreased expression of WNT4 mRNA CTD PMID:31256213 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
G Wnt5a Wnt family member 5A increases expression ISO hydroquinone results in increased expression of WNT5A mRNA CTD PMID:22960397 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Wrn WRN RecQ like helicase multiple interactions
decreases response to substance
increases response to substance		 ISO WRN gene mutant form promotes the reaction [hydroquinone results in increased expression of H2AX protein alternative form]; WRN protein affects the reaction [hydroquinone results in increased acetylation of TP53 protein]; WRN protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; WRN protein affects the reaction [hydroquinone results in increased expression of TP53 protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]
WRN protein results in decreased susceptibility to hydroquinone
WRN gene mutant form results in increased susceptibility to hydroquinone		 CTD PMID:17875398 PMID:18978339 PMID:19064679 PMID:21267443 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
G Xaf1 XIAP associated factor 1 decreases expression ISO hydroquinone results in decreased expression of XAF1 mRNA CTD PMID:31256213 NCBI chr10:56,917,378...56,929,791
Ensembl chr10:56,917,121...56,929,770 		JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions
affects response to substance
decreases expression
increases splicing
increases expression		 ISO [XBP1 protein affects the susceptibility to hydroquinone] which affects the expression of DDIT3 protein; hydroquinone promotes the reaction [XBP1 protein affects the expression of BCL2 mRNA]; hydroquinone promotes the reaction [XBP1 protein affects the expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 protein]
hydroquinone results in decreased expression of XBP1 protein alternative form
Resveratrol inhibits the reaction [hydroquinone results in increased expression of XBP1 protein]; XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased phosphorylation of EIF2S1 protein]
hydroquinone results in increased splicing of XBP1 mRNA		 CTD PMID:24053669 PMID:32334435 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Xkrx XK related, X-linked increases expression ISO hydroquinone results in increased expression of XKRX mRNA CTD PMID:31256213 NCBI chr  X:97,341,158...97,353,175
Ensembl chr  X:97,341,152...97,354,759 		JBrowse link
G Xpnpep3 X-prolyl aminopeptidase 3 decreases expression ISO hydroquinone results in decreased expression of XPNPEP3 mRNA CTD PMID:31256213 NCBI chr 7:112,926,154...112,978,793
Ensembl chr 7:112,926,248...112,974,878 		JBrowse link
G Zfp2 zinc finger protein 2 decreases expression ISO hydroquinone results in decreased expression of ZFP2 mRNA CTD PMID:31256213 NCBI chr10:35,209,187...35,228,849
Ensembl chr10:35,207,260...35,228,853 		JBrowse link
G Zfp36 zinc finger protein 36 multiple interactions
decreases expression		 ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [hydroquinone results in decreased expression of ZFP36 protein]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of ZFP36 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in decreased expression of ZFP36 protein]; ZFP36 protein inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]; ZFP36 protein inhibits the reaction [hydroquinone results in increased expression of TNF protein] CTD PMID:23288922 PMID:35302183 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
hydroquinone O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca13 ATP binding cassette subfamily A member 13 decreases expression ISO Arbutin results in decreased expression of ABCA13 mRNA CTD PMID:17103032 NCBI chr14:83,873,397...84,376,138
Ensembl chr14:83,873,940...84,375,075 		JBrowse link
G Abca8a ATP-binding cassette, subfamily A (ABC1), member 8a decreases expression ISO Arbutin results in decreased expression of ABCA10 mRNA CTD PMID:17103032 NCBI chr10:95,002,334...95,072,315
Ensembl chr10:95,002,334...95,072,375 		JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression ISO Arbutin results in decreased expression of ACMSD mRNA CTD PMID:17103032 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
G Acvrl1 activin A receptor like type 1 decreases expression ISO Arbutin results in decreased expression of ACVRL1 mRNA CTD PMID:17103032 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression ISO Arbutin results in decreased expression of ADAM19 mRNA CTD PMID:17103032 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105 		JBrowse link
G Adam7 ADAM metallopeptidase domain 7 increases expression ISO Arbutin results in increased expression of ADAM7 mRNA CTD PMID:17103032 NCBI chr15:42,833,796...42,882,201
Ensembl chr15:42,833,796...42,882,201 		JBrowse link
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 decreases expression ISO Arbutin results in decreased expression of ADAMTS3 mRNA CTD PMID:17103032 NCBI chr14:18,231,128...18,437,771
Ensembl chr14:18,231,165...18,435,556 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 decreases expression ISO Arbutin results in decreased expression of ADAMTS9 mRNA CTD PMID:17103032 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression ISO Arbutin results in decreased expression of ADRB3 mRNA CTD PMID:17103032 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Aebp2 AE binding protein 2 increases expression ISO Arbutin results in increased expression of AEBP2 mRNA CTD PMID:17103032 NCBI chr 4:173,527,881...173,566,033
Ensembl chr 4:173,528,344...173,593,100 		JBrowse link
G Afap1 actin filament associated protein 1 decreases expression ISO Arbutin results in decreased expression of AFAP1 mRNA CTD PMID:17103032 NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263 		JBrowse link
G Agbl4 AGBL carboxypeptidase 4 decreases expression ISO Arbutin results in decreased expression of AGBL4 mRNA CTD PMID:17103032 NCBI chr 5:125,254,963...126,534,367
Ensembl chr 5:125,254,956...126,534,367 		JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 decreases expression ISO Arbutin results in decreased expression of AGPAT3 mRNA CTD PMID:17103032 NCBI chr20:10,330,960...10,415,358
Ensembl chr20:10,384,507...10,415,358 		JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression ISO Arbutin results in decreased expression of AHNAK mRNA CTD PMID:17103032 NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO Arbutin results in decreased expression of AKT1 mRNA CTD PMID:17103032 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of Arbutin CTD PMID:8831264 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Amtn amelotin decreases expression ISO Arbutin results in decreased expression of AMTN mRNA CTD PMID:17103032 NCBI chr14:19,648,624...19,661,181
Ensembl chr14:19,648,625...19,661,181 		JBrowse link
G Ankrd17 ankyrin repeat domain 17 increases expression ISO Arbutin results in increased expression of ANKRD17 mRNA CTD PMID:17103032 NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Ankrd23 ankyrin repeat domain 23 increases expression ISO Arbutin results in increased expression of ANKRD23 mRNA CTD PMID:17103032 NCBI chr 9:38,773,234...38,778,705
Ensembl chr 9:38,773,240...38,779,839 		JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression ISO Arbutin results in decreased expression of AP1S1 mRNA CTD PMID:17103032 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713 		JBrowse link
G Apom apolipoprotein M increases expression ISO Arbutin results in increased expression of APOM mRNA CTD PMID:17103032 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550 		JBrowse link
G Aptx aprataxin decreases expression ISO Arbutin results in decreased expression of APTX mRNA CTD PMID:17103032 NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855 		JBrowse link
G Arfip2 ADP-ribosylation factor interacting protein 2 decreases expression ISO Arbutin results in decreased expression of ARFIP2 mRNA CTD PMID:17103032 NCBI chr 1:159,974,255...159,980,398
Ensembl chr 1:159,974,201...159,980,336 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO Arbutin results in decreased expression of ARHGEF2 mRNA CTD PMID:17103032 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Arl2 ADP-ribosylation factor like GTPase 2 decreases expression ISO Arbutin results in decreased expression of ARL2 mRNA CTD PMID:17103032 NCBI chr 1:203,434,129...203,446,156
Ensembl chr 1:203,434,129...203,446,119 		JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 increases expression ISO Arbutin results in increased expression of ARL6IP1 mRNA CTD PMID:17103032 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994 		JBrowse link
G Arx aristaless related homeobox decreases expression ISO Arbutin results in decreased expression of ARX mRNA CTD PMID:17103032 NCBI chr  X:58,016,233...58,028,149
Ensembl chr  X:58,016,233...58,028,142 		JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 increases expression ISO Arbutin results in increased expression of ASAP1 mRNA CTD PMID:17103032 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754 		JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 decreases expression ISO Arbutin results in decreased expression of ASAP3 mRNA CTD PMID:17103032 NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073 		JBrowse link
G Atf6b activating transcription factor 6 beta decreases expression ISO Arbutin results in decreased expression of ATF6B mRNA CTD PMID:17103032 NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894 		JBrowse link
G B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 decreases expression ISO Arbutin results in decreased expression of B4GALNT4 mRNA CTD PMID:17103032 NCBI chr 1:196,171,394...196,182,294
Ensembl chr 1:196,171,394...196,182,294 		JBrowse link
G Bag5 BAG cochaperone 5 decreases expression ISO Arbutin results in decreased expression of BAG5 mRNA CTD PMID:17103032 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor increases expression ISO Arbutin results in increased expression of BCAS2 mRNA CTD PMID:17103032 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389 		JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase decreases expression ISO Arbutin results in decreased expression of BCKDK mRNA CTD PMID:17103032 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B decreases expression ISO Arbutin results in decreased expression of BMPR1B mRNA CTD PMID:17103032 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G Bnip2 BCL2 interacting protein 2 increases expression ISO Arbutin results in increased expression of BNIP2 mRNA CTD PMID:17103032 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590 		JBrowse link
G Brsk1 BR serine/threonine kinase 1 decreases expression ISO Arbutin results in decreased expression of BRSK1 mRNA CTD PMID:17103032 NCBI chr 1:69,134,166...69,159,947
Ensembl chr 1:69,134,565...69,160,365 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO Arbutin results in decreased expression of BST2 mRNA CTD PMID:17103032 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979 		JBrowse link
G C1h19orf33 similar to human chromosome 19 open reading frame 33 decreases expression ISO Arbutin results in decreased expression of C19ORF33 mRNA CTD PMID:17103032 NCBI chr 1:84,549,830...84,550,666
Ensembl chr 1:84,549,831...84,550,664 		JBrowse link
G C1qb complement C1q B chain decreases expression ISO Arbutin results in decreased expression of C1QB mRNA CTD PMID:17103032 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407 		JBrowse link
G C5h1orf87 similar to human chromosome 1 open reading frame 87 decreases expression ISO Arbutin results in decreased expression of C1ORF87 mRNA CTD PMID:17103032 NCBI chr 5:111,342,381...111,411,576
Ensembl chr 5:111,342,387...111,411,590 		JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 decreases expression ISO Arbutin results in decreased expression of CACNG7 mRNA CTD PMID:17103032 NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006 		JBrowse link
G Capns2 calpain, small subunit 2 increases expression ISO Arbutin results in increased expression of CAPNS2 mRNA CTD PMID:17103032 NCBI chr19:14,104,334...14,105,276 JBrowse link
G Casp8 caspase 8 decreases expression ISO Arbutin results in decreased expression of CASP8 mRNA CTD PMID:17103032 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase multiple interactions EXP Arbutin inhibits the reaction [potassium bromate results in decreased activity of CAT protein] CTD PMID:36284482 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbx6 chromobox 6 decreases expression ISO Arbutin results in decreased expression of CBX6 mRNA CTD PMID:17103032 NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:111,372,980...111,383,091 		JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO Arbutin results in increased expression of CCAR1 mRNA CTD PMID:17103032 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526 		JBrowse link
G Ccdc170 coiled-coil domain containing 170 decreases expression ISO Arbutin results in decreased expression of CCDC170 mRNA CTD PMID:17103032 NCBI chr 1:40,945,607...41,050,010
Ensembl chr 1:40,945,961...41,085,040 		JBrowse link
G Ccdc28b coiled coil domain containing 28B decreases expression ISO Arbutin results in decreased expression of CCDC28B mRNA CTD PMID:17103032 NCBI chr 5:141,962,275...141,967,278
Ensembl chr 5:141,962,276...141,967,382 		JBrowse link
G Ccnyl1 cyclin Y-like 1 increases expression ISO Arbutin results in increased expression of CCNYL1 mRNA CTD PMID:17103032 NCBI chr 9:66,071,721...66,121,742
Ensembl chr 9:66,071,543...66,107,999 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases expression ISO Arbutin results in increased expression of CCT8 mRNA CTD PMID:17103032 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Cd151 CD151 molecule (Raph blood group) decreases expression ISO Arbutin results in decreased expression of CD151 mRNA CTD PMID:17103032 NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753 		JBrowse link
G Cd160 CD160 molecule decreases expression ISO Arbutin results in decreased expression of CD160 mRNA CTD PMID:17103032 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Cd2bp2 Cd2 (cytoplasmic tail) binding protein 2 decreases expression ISO Arbutin results in decreased expression of CD2BP2 mRNA CTD PMID:17103032 NCBI chr 1:181,809,399...181,815,269
Ensembl chr 1:181,809,406...181,813,448 		JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex decreases expression ISO Arbutin results in decreased expression of CD3G mRNA CTD PMID:17103032 NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147 		JBrowse link
G Cdin1 CDAN1 interacting nuclease 1 increases expression ISO Arbutin results in increased expression of CDIN1 mRNA CTD PMID:17103032 NCBI chr 3:102,441,553...102,646,935
Ensembl chr 3:102,441,704...102,646,682 		JBrowse link
G Cdk16 cyclin-dependent kinase 16 decreases expression ISO Arbutin results in decreased expression of CDK16 mRNA CTD PMID:17103032 NCBI chr  X:1,492,814...1,504,309
Ensembl chr  X:1,492,814...1,504,148 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression ISO Arbutin results in decreased expression of CEACAM1 mRNA CTD PMID:17103032 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cfap161 cilia and flagella associated protein 161 decreases expression ISO Arbutin results in decreased expression of CFAP161 mRNA CTD PMID:17103032 NCBI chr 1:137,743,783...137,768,685
Ensembl chr 1:137,743,784...137,768,730 		JBrowse link
G Cfap70 cilia and flagella associated protein 70 decreases expression ISO Arbutin results in decreased expression of CFAP70 mRNA CTD PMID:17103032 NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014 		JBrowse link
G Clec4b2 C-type lectin domain family 4, member B2 decreases expression ISO Arbutin results in decreased expression of CLEC4C mRNA CTD PMID:17103032 NCBI chr 4:156,462,742...156,486,240
Ensembl chr 4:156,462,742...156,486,240 		JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 decreases expression ISO Arbutin results in decreased expression of CNKSR2 mRNA CTD PMID:17103032 NCBI chr  X:36,908,135...37,148,337
Ensembl chr  X:36,907,850...37,150,555 		JBrowse link
G Col17a1 collagen type XVII alpha 1 chain decreases expression ISO Arbutin results in decreased expression of COL17A1 mRNA CTD PMID:17103032 NCBI chr 1:246,530,589...246,577,559
Ensembl chr 1:246,531,367...246,577,632 		JBrowse link
G Cpb1 carboxypeptidase B1 decreases expression ISO Arbutin results in decreased expression of CPB1 mRNA CTD PMID:17103032 NCBI chr 2:102,755,241...102,785,628
Ensembl chr 2:102,755,241...102,785,628 		JBrowse link
G Cpe carboxypeptidase E increases expression ISO Arbutin results in increased expression of CPE mRNA CTD PMID:17103032 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Cpne5 copine 5 increases expression ISO Arbutin results in increased expression of CPNE5 mRNA CTD PMID:17103032 NCBI chr20:7,206,742...7,289,309
Ensembl chr20:7,206,742...7,288,883 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Arbutin results in decreased expression of CYP17A1 mRNA; Arbutin results in decreased expression of CYP17A1 protein CTD PMID:37783241 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 increases expression ISO Arbutin results in increased expression of CYP2U1 mRNA CTD PMID:17103032 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882 		JBrowse link
G Cyrib CYFIP related Rac1 interactor B increases expression ISO Arbutin results in increased expression of CYRIB mRNA CTD PMID:17103032 NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686 		JBrowse link
G Ddx46 DEAD-box helicase 46 increases expression ISO Arbutin results in increased expression of DDX46 mRNA CTD PMID:17103032 NCBI chr17:8,942,070...8,988,440
Ensembl chr17:8,944,454...8,988,439 		JBrowse link
G Diaph2 diaphanous-related formin 2 decreases expression ISO Arbutin results in decreased expression of DIAPH2 mRNA CTD PMID:17103032 NCBI chr  X:92,395,189...93,234,521
Ensembl chr  X:92,395,251...93,229,869 		JBrowse link
G Dlgap4 DLG associated protein 4 increases expression ISO Arbutin results in increased expression of DLGAP4 mRNA CTD PMID:17103032 NCBI chr 3:145,124,189...145,271,791
Ensembl chr 3:145,175,479...145,270,490 		JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO Arbutin results in decreased expression of DLX1 mRNA CTD PMID:17103032 NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780 		JBrowse link
G Dmxl1 Dmx-like 1 decreases expression ISO Arbutin results in decreased expression of DMXL1 mRNA CTD PMID:17103032 NCBI chr18:42,993,292...43,163,457
Ensembl chr18:42,993,340...43,163,456 		JBrowse link
G Dnah7 dynein, axonemal, heavy chain 7 decreases expression ISO Arbutin results in decreased expression of DNAH7 mRNA CTD PMID:17103032 NCBI chr 9:54,960,235...55,266,529
Ensembl chr 9:54,960,440...55,262,297 		JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 decreases expression ISO Arbutin results in decreased expression of DNAI3 mRNA CTD PMID:17103032 NCBI chr 2:234,947,910...235,006,173
Ensembl chr 2:234,929,677...235,006,173 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Arbutin results in increased expression of DNAJB9 mRNA CTD PMID:17103032 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dpp7 dipeptidylpeptidase 7 decreases expression ISO Arbutin results in decreased expression of DPP7 mRNA CTD PMID:17103032 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Arbutin results in decreased expression of DPYSL2 mRNA CTD PMID:17103032 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression ISO Arbutin results in increased expression of ECE1 mRNA CTD PMID:17103032 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression ISO Arbutin results in increased expression of EEPD1 mRNA CTD PMID:17103032 NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340 		JBrowse link
G Efhc2 EF-hand domain containing 2 decreases expression ISO Arbutin results in decreased expression of EFHC2 mRNA CTD PMID:17103032 NCBI chr  X:5,360,499...5,564,004
Ensembl chr  X:5,360,617...5,560,970 		JBrowse link
G Efl1 elongation factor like GTPase 1 increases expression ISO Arbutin results in increased expression of EFL1 mRNA CTD PMID:17103032 NCBI chr 1:136,638,527...136,763,518
Ensembl chr 1:136,638,527...136,763,518 		JBrowse link
G Efna3 ephrin A3 decreases expression ISO Arbutin results in decreased expression of EFNA3 mRNA CTD PMID:17103032 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Efs embryonal Fyn-associated substrate decreases expression ISO Arbutin results in decreased expression of EFS mRNA CTD PMID:17103032 NCBI chr15:28,392,417...28,403,016
Ensembl chr15:28,392,187...28,401,902 		JBrowse link
G Eid1 EP300 interacting inhibitor of differentiation 1 increases expression ISO Arbutin results in increased expression of EID1 mRNA CTD PMID:17103032 NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752 		JBrowse link
G Elane elastase, neutrophil expressed decreases expression ISO Arbutin results in decreased expression of ELANE mRNA CTD PMID:17103032 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Emx2 empty spiracles homeobox 2 decreases expression ISO Arbutin results in decreased expression of EMX2 mRNA CTD PMID:17103032 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression ISO Arbutin results in decreased expression of ENPP1 mRNA CTD PMID:17103032 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor increases expression ISO Arbutin results in increased expression of EPS8 mRNA CTD PMID:17103032 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873 		JBrowse link
G Epx eosinophil peroxidase increases expression ISO Arbutin results in increased expression of EPX mRNA CTD PMID:17103032 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952 		JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 increases expression ISO Arbutin results in increased expression of ERC1 mRNA CTD PMID:17103032 NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639 		JBrowse link
G Esr2 estrogen receptor 2 increases expression ISO Arbutin results in increased expression of ESR2 protein CTD PMID:29360751 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Evi2b ecotropic viral integration site 2B decreases expression ISO Arbutin results in decreased expression of EVI2B mRNA CTD PMID:17103032 NCBI chr10:64,472,693...64,474,311
Ensembl chr10:64,471,505...64,481,560 		JBrowse link
G Exd1 exonuclease 3'-5' domain containing 1 decreases expression ISO Arbutin results in decreased expression of EXD1 mRNA CTD PMID:17103032 NCBI chr 3:106,507,839...106,535,922
Ensembl chr 3:106,508,076...106,535,922 		JBrowse link
G F13b coagulation factor XIII B chain decreases expression ISO Arbutin results in decreased expression of F13B mRNA CTD PMID:17103032 NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381 		JBrowse link
G Fam3d FAM3 metabolism regulating signaling molecule D decreases expression ISO Arbutin results in decreased expression of FAM3D mRNA CTD PMID:17103032 NCBI chr15:16,538,881...16,574,468
Ensembl chr15:16,539,489...16,573,034 		JBrowse link
G Fancd2os FANCD2 opposite strand decreases expression ISO Arbutin results in decreased expression of FANCD2OS mRNA CTD PMID:17103032 NCBI chr 4:146,740,863...146,747,547
Ensembl chr 4:146,740,863...146,747,569 		JBrowse link
G Faslg Fas ligand decreases expression ISO Arbutin results in decreased expression of FASLG mRNA CTD PMID:17103032 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fbxo11 F-box protein 11 increases expression ISO Arbutin results in increased expression of FBXO11 mRNA CTD PMID:17103032 NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662 		JBrowse link
G Fbxo16 F-box protein 16 increases expression ISO Arbutin results in increased expression of FBXO16 mRNA CTD PMID:17103032 NCBI chr15:39,492,268...39,541,493
Ensembl chr15:39,492,377...39,541,480 		JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO Arbutin results in decreased expression of FGF5 mRNA CTD PMID:17103032 NCBI chr14:11,323,827...11,346,164
Ensembl chr14:11,325,334...11,345,997 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO Arbutin results in decreased expression of FGFR3 mRNA CTD PMID:17103032 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fmnl3 formin-like 3 decreases expression ISO Arbutin results in decreased expression of FMNL3 mRNA CTD PMID:17103032 NCBI chr 7:130,454,270...130,505,626
Ensembl chr 7:130,454,275...130,505,626 		JBrowse link
G Fpgt fucose-1-phosphate guanylyltransferase decreases expression ISO Arbutin results in decreased expression of FPGT mRNA CTD PMID:17103032 NCBI chr 2:244,099,031...244,119,967
Ensembl chr 2:244,099,076...244,119,899 		JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 decreases expression ISO Arbutin results in decreased expression of FRAS1 mRNA CTD PMID:17103032 NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726 		JBrowse link
G Frmpd4 FERM and PDZ domain containing 4 decreases expression ISO Arbutin results in decreased expression of FRMPD4 mRNA CTD PMID:17103032 NCBI chr  X:25,853,849...26,814,642
Ensembl chr  X:25,853,934...26,814,637 		JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression ISO Arbutin results in increased expression of FSHB protein CTD PMID:29360751 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Galc galactosylceramidase increases expression ISO Arbutin results in increased expression of GALC mRNA CTD PMID:17103032 NCBI chr 6:117,452,888...117,522,281
Ensembl chr 6:117,452,895...117,515,830 		JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 increases expression ISO Arbutin results in increased expression of GAREM1 mRNA CTD PMID:17103032 NCBI chr18:12,420,169...12,585,323
Ensembl chr18:12,423,882...12,585,345 		JBrowse link
G Get3 guided entry of tail-anchored proteins factor 3, ATPase decreases expression ISO Arbutin results in decreased expression of GET3 mRNA CTD PMID:17103032 NCBI chr19:23,130,109...23,138,196
Ensembl chr19:23,130,109...23,138,193 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 decreases expression ISO Arbutin results in decreased expression of GIPC1 mRNA CTD PMID:17103032 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Glt8d2 glycosyltransferase 8 domain containing 2 decreases expression ISO Arbutin results in decreased expression of GLT8D2 mRNA CTD PMID:17103032 NCBI chr 7:21,029,534...21,081,081
Ensembl chr 7:21,029,525...21,081,080 		JBrowse link
G Gmpr guanosine monophosphate reductase decreases expression ISO Arbutin results in decreased expression of GMPR mRNA CTD PMID:17103032 NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621 		JBrowse link
G Gnl2 G protein nucleolar 2 increases expression ISO Arbutin results in increased expression of GNL2 mRNA CTD PMID:17103032 NCBI chr 5:137,293,141...137,318,528
Ensembl chr 5:137,293,081...137,318,526 		JBrowse link
G Gpc3 glypican 3 decreases expression ISO Arbutin results in decreased expression of GPC3 mRNA CTD PMID:17103032 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 increases expression ISO Arbutin results in increased expression of GPD2 mRNA CTD PMID:17103032 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression ISO Arbutin results in increased expression of GPER1 protein CTD PMID:29360751 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gpr155 G protein-coupled receptor 155 decreases expression ISO Arbutin results in decreased expression of GPR155 mRNA CTD PMID:17103032 NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275 		JBrowse link
G Gpr26 G protein-coupled receptor 26 decreases expression ISO Arbutin results in decreased expression of GPR26 mRNA CTD PMID:17103032 NCBI chr 1:186,766,001...186,805,435
Ensembl chr 1:186,767,062...186,784,568 		JBrowse link
G Gpr32 G protein-coupled receptor 32 increases expression ISO Arbutin results in increased expression of GPR32 mRNA CTD PMID:17103032 NCBI chr 1:94,756,863...94,757,895 JBrowse link
G Gpr55 G protein-coupled receptor 55 decreases expression ISO Arbutin results in decreased expression of GPR55 mRNA CTD PMID:17103032 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613 		JBrowse link
G Gprc5d G protein-coupled receptor, class C, group 5, member D decreases expression ISO Arbutin results in decreased expression of GPRC5D mRNA CTD PMID:17103032 NCBI chr 4:167,943,523...167,955,616
Ensembl chr 4:167,943,523...167,955,616 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO
EXP		 Arbutin inhibits the reaction [Ethanol results in increased expression of GPT protein] CTD PMID:34346143 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gsdma gasdermin A decreases expression ISO Arbutin results in decreased expression of GSDMA mRNA CTD PMID:17103032 NCBI chr10:83,614,336...83,639,543
Ensembl chr10:83,627,051...83,639,543 		JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 decreases expression ISO Arbutin results in decreased expression of GUCY1A2 mRNA CTD PMID:17103032 NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203 		JBrowse link
G H1f1 H1.1 linker histone, cluster member increases expression ISO Arbutin results in increased expression of H1-1 mRNA CTD PMID:17103032 NCBI chr17:41,366,268...41,367,011
Ensembl chr17:41,366,268...41,367,011 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 increases expression ISO Arbutin results in increased expression of HAND1 mRNA CTD PMID:17103032 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 increases expression ISO Arbutin results in increased expression of H2AC6 mRNA CTD PMID:17103032 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO Arbutin results in decreased expression of HLF mRNA CTD PMID:17103032 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP Arbutin inhibits the reaction [Ethanol results in decreased expression of HMOX1 mRNA] CTD PMID:34346143 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hoxb8 homeo box B8 decreases expression ISO Arbutin results in decreased expression of HOXB8 mRNA CTD PMID:17103032 NCBI chr10:81,248,313...81,251,261
Ensembl chr10:81,248,887...81,250,638 		JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 decreases expression ISO Arbutin results in decreased expression of HPS3 mRNA CTD PMID:17103032 NCBI chr 2:102,484,574...102,527,580
Ensembl chr 2:102,484,574...102,526,047 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO
EXP		 Arbutin results in decreased expression of HSD3B1 mRNA
Arbutin results in decreased expression of HSD3B1 mRNA; Arbutin results in decreased expression of HSD3B1 protein		 CTD PMID:17103032 PMID:37783241 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 increases expression ISO Arbutin results in increased expression of HTATSF1 mRNA CTD PMID:17103032 NCBI chr  X:134,935,426...134,949,607
Ensembl chr  X:134,935,426...134,949,607 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO Arbutin results in decreased expression of IFIT3 mRNA CTD PMID:17103032 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 decreases expression ISO Arbutin results in decreased expression of IGDCC3 mRNA CTD PMID:17103032 NCBI chr 8:65,661,165...65,707,961
Ensembl chr 8:65,661,196...65,707,959 		JBrowse link
G Il23a interleukin 23 subunit alpha decreases expression ISO Arbutin results in decreased expression of IL23A mRNA CTD PMID:17103032 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il3ra interleukin 3 receptor subunit alpha increases expression ISO Arbutin results in increased expression of IL3RA mRNA CTD PMID:17103032 NCBI chr12:16,318,081...16,323,781
Ensembl chr12:16,318,081...16,323,484 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP Arbutin inhibits the reaction [Ethanol results in increased expression of IL6 protein] CTD PMID:34346143 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer decreases expression ISO Arbutin results in decreased expression of IL6ST mRNA CTD PMID:17103032 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha decreases expression ISO Arbutin results in decreased expression of INA mRNA CTD PMID:17103032 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B increases expression ISO Arbutin results in increased expression of INPP4B mRNA CTD PMID:17103032 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Arbutin results in decreased expression of JUN mRNA CTD PMID:17103032 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnab3 potassium voltage-gated channel subfamily A regulatory beta subunit 3 decreases expression ISO Arbutin results in decreased expression of KCNAB3 mRNA CTD PMID:17103032 NCBI chr10:54,047,830...54,056,401
Ensembl chr10:54,047,825...54,054,174 		JBrowse link
G Kctd17 potassium channel tetramerization domain containing 17 decreases expression ISO Arbutin results in decreased expression of KCTD17 mRNA CTD PMID:17103032 NCBI chr 7:109,979,060...110,009,091
Ensembl chr 7:109,979,060...110,008,927 		JBrowse link
G Kif26b kinesin family member 26B decreases expression ISO Arbutin results in decreased expression of KIF26B mRNA CTD PMID:17103032 NCBI chr13:90,282,821...90,689,058
Ensembl chr13:90,283,404...90,682,811 		JBrowse link
G Klhl13 kelch-like family member 13 increases expression ISO Arbutin results in increased expression of KLHL13 mRNA CTD PMID:17103032 NCBI chr  X:113,942,309...114,107,299
Ensembl chr  X:113,942,309...114,107,321 		JBrowse link
G Lctl lactase-like decreases expression ISO Arbutin results in decreased expression of LCTL mRNA CTD PMID:17103032 NCBI chr 8:64,618,356...64,654,851
Ensembl chr 8:64,618,350...64,639,357 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression EXP Arbutin results in decreased expression of LHCGR mRNA; Arbutin results in decreased expression of LHCGR protein CTD PMID:37783241 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Lrp5 LDL receptor related protein 5 decreases expression ISO Arbutin results in decreased expression of LRP5 mRNA CTD PMID:17103032 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Lrp6 LDL receptor related protein 6 decreases expression ISO Arbutin results in decreased expression of LRP6 mRNA CTD PMID:17103032 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Lrrc4 leucine rich repeat containing 4 decreases expression ISO Arbutin results in decreased expression of LRRC4 mRNA CTD PMID:17103032 NCBI chr 4:57,433,518...57,437,114
Ensembl chr 4:57,433,428...57,437,911 		JBrowse link
G Lrrtm4 leucine rich repeat transmembrane neuronal 4 decreases expression ISO Arbutin results in decreased expression of LRRTM4 mRNA CTD PMID:17103032 NCBI chr 4:112,545,874...113,338,713
Ensembl chr 4:112,545,917...113,335,865 		JBrowse link
G Mafk MAF bZIP transcription factor K decreases expression ISO Arbutin results in decreased expression of MAFK mRNA CTD PMID:17103032 NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048 		JBrowse link
G Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 decreases expression ISO Arbutin results in decreased expression of MAP4K5 mRNA CTD PMID:17103032 NCBI chr 6:88,284,087...88,377,118
Ensembl chr 6:88,284,094...88,376,799 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases expression ISO Arbutin results in decreased expression of MAPK8 mRNA CTD PMID:17103032 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor increases expression ISO Arbutin results in increased expression of MCM8 mRNA CTD PMID:17103032 NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008 		JBrowse link
G Mdfi MyoD family inhibitor decreases expression ISO Arbutin results in decreased expression of MDFI mRNA CTD PMID:17103032 NCBI chr 9:13,156,806...13,175,218
Ensembl chr 9:13,156,866...13,175,217 		JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression ISO Arbutin results in decreased expression of MFAP4 mRNA CTD PMID:17103032 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155 		JBrowse link
G Midn midnolin decreases expression ISO Arbutin results in decreased expression of MIDN mRNA CTD PMID:17103032 NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO Arbutin results in increased expression of MKI67 mRNA CTD PMID:17103032 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmgt1 membrane magnesium transporter 1 increases expression ISO Arbutin results in increased expression of MMGT1 mRNA CTD PMID:17103032 NCBI chr  X:134,408,463...134,420,798
Ensembl chr  X:134,408,466...134,420,729 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like decreases expression ISO Arbutin results in decreased expression of MTHFD1L mRNA CTD PMID:17103032 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression ISO Arbutin results in decreased expression of MVD mRNA CTD PMID:17103032 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971 		JBrowse link
G Myo3b myosin IIIB decreases expression ISO Arbutin results in decreased expression of MYO3B mRNA CTD PMID:17103032 NCBI chr 3:54,820,225...55,228,518
Ensembl chr 3:54,820,251...55,227,373 		JBrowse link
G Ncald neurocalcin delta decreases expression ISO Arbutin results in decreased expression of NCALD mRNA CTD PMID:17103032 NCBI chr 7:68,532,671...68,964,740
Ensembl chr 7:68,534,421...68,964,496 		JBrowse link
G Negr1 neuronal growth regulator 1 decreases expression ISO Arbutin results in decreased expression of NEGR1 mRNA CTD PMID:17103032 NCBI chr 2:245,624,460...246,359,605
Ensembl chr 2:245,624,435...246,356,730 		JBrowse link
G Neu4 neuraminidase 4 increases expression ISO Arbutin results in increased expression of NEU4 mRNA CTD PMID:17103032 NCBI chr 9:94,396,920...94,402,576
Ensembl chr 9:94,396,920...94,402,576 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Arbutin inhibits the reaction [Ethanol results in decreased expression of NFE2L2 mRNA] CTD PMID:34346143 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 decreases expression ISO Arbutin results in decreased expression of NKD1 mRNA CTD PMID:17103032 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380 		JBrowse link
G Nmi N-myc (and STAT) interactor increases expression ISO Arbutin results in increased expression of NMI mRNA CTD PMID:17103032 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Noxred1 NADP-dependent oxidoreductase domain containing 1 decreases expression ISO Arbutin results in decreased expression of NOXRED1 mRNA CTD PMID:17103032 NCBI chr 6:106,862,350...106,888,113
Ensembl chr 6:106,862,343...106,884,712 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP Arbutin inhibits the reaction [Ethanol results in increased expression of NQO1 mRNA] CTD PMID:34346143 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 increases expression ISO Arbutin results in increased expression of NR2F1 mRNA CTD PMID:17103032 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123 		JBrowse link
G Nrp2 neuropilin 2 increases expression ISO Arbutin results in increased expression of NRP2 mRNA CTD PMID:17103032 NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958 		JBrowse link
G Ntf4 neurotrophin 4 decreases expression ISO Arbutin results in decreased expression of NTF4 mRNA CTD PMID:17103032 NCBI chr 1:95,893,560...95,896,391
Ensembl chr 1:95,893,457...95,897,243 		JBrowse link
G Olfml1 olfactomedin-like 1 decreases expression ISO Arbutin results in decreased expression of OLFML1 mRNA CTD PMID:17103032 NCBI chr 1:161,478,129...161,502,541
Ensembl chr 1:161,478,242...161,502,537 		JBrowse link
G Osbp2 oxysterol binding protein 2 decreases expression ISO Arbutin results in decreased expression of OSBP2 mRNA CTD PMID:17103032 NCBI chr14:78,585,088...78,746,785
Ensembl chr14:78,585,089...78,746,786 		JBrowse link
G Osbpl11 oxysterol binding protein-like 11 increases expression ISO Arbutin results in increased expression of OSBPL11 mRNA CTD PMID:17103032 NCBI chr11:67,533,669...67,616,795
Ensembl chr11:67,533,672...67,596,444 		JBrowse link
G Otx1 orthodenticle homeobox 1 decreases expression ISO Arbutin results in decreased expression of OTX1 mRNA CTD PMID:17103032 NCBI chr14:96,082,146...96,089,161
Ensembl chr14:96,082,151...96,089,086 		JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 decreases expression ISO Arbutin results in decreased expression of PACSIN2 mRNA CTD PMID:17103032 NCBI chr 7:114,505,525...114,599,087
Ensembl chr 7:114,505,152...114,598,546 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase increases expression ISO Arbutin results in increased expression of PARG mRNA CTD PMID:17103032 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273 		JBrowse link
G Pcgf6 polycomb group ring finger 6 increases expression ISO Arbutin results in increased expression of PCGF6 mRNA CTD PMID:17103032 NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914 		JBrowse link
G Pcmtd2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 increases expression ISO Arbutin results in increased expression of PCMTD2 mRNA CTD PMID:17103032 NCBI chr 3:168,960,312...168,979,504
Ensembl chr 3:168,960,305...168,979,497 		JBrowse link
G Pcnx2 pecanex 2 decreases expression ISO Arbutin results in decreased expression of PCNX2 mRNA CTD PMID:17103032 NCBI chr19:53,718,920...53,869,559
Ensembl chr19:53,718,655...53,871,364 		JBrowse link
G Pdzk1 PDZ domain containing 1 decreases expression ISO Arbutin results in decreased expression of PDZK1 mRNA CTD PMID:17103032 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514 		JBrowse link
G Perm1 PPARGC1 and ESRR induced regulator, muscle 1 decreases expression ISO Arbutin results in decreased expression of PERM1 mRNA CTD PMID:17103032 NCBI chr 5:166,800,030...166,805,323
Ensembl chr 5:166,800,030...166,805,323 		JBrowse link
G Pf4 platelet factor 4 decreases expression ISO Arbutin results in decreased expression of PF4 mRNA CTD PMID:17103032 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Pgm2 phosphoglucomutase 2 increases expression ISO Arbutin results in increased expression of PGM2 mRNA CTD PMID:17103032 NCBI chr14:44,166,314...44,199,828
Ensembl chr14:44,164,425...44,199,967 		JBrowse link
G Pigq phosphatidylinositol glycan anchor biosynthesis, class Q decreases expression ISO Arbutin results in decreased expression of PIGQ mRNA CTD PMID:17103032 NCBI chr10:14,942,571...14,958,584
Ensembl chr10:14,942,577...14,958,584 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 decreases expression ISO Arbutin results in decreased expression of PIN1 mRNA CTD PMID:17103032 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785 		JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta increases expression ISO Arbutin results in increased expression of PITPNB mRNA CTD PMID:17103032 NCBI chr12:45,249,308...45,298,388
Ensembl chr12:45,249,333...45,298,314 		JBrowse link
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin decreases expression ISO Arbutin results in decreased expression of PKHD1 mRNA CTD PMID:17103032 NCBI chr 9:22,547,396...23,037,443
Ensembl chr 9:22,549,513...23,037,381 		JBrowse link
G Poglut2 protein O-glucosyltransferase 2 increases expression ISO Arbutin results in increased expression of POGLUT2 mRNA CTD PMID:17103032 NCBI chr 9:46,256,388...46,268,714
Ensembl chr 9:46,256,390...46,268,532 		JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit increases expression ISO Arbutin results in increased expression of POLE2 mRNA CTD PMID:17103032 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305 		JBrowse link
G Pphln1 periphilin 1 increases expression ISO Arbutin results in increased expression of PPHLN1 mRNA CTD PMID:17103032 NCBI chr 7:124,538,594...124,629,985
Ensembl chr 7:124,538,627...124,629,985 		JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein decreases expression ISO Arbutin results in decreased expression of PRG2 mRNA CTD PMID:17103032 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101 		JBrowse link
G Prkx protein kinase cAMP-dependent X-linked catalytic subunit decreases expression ISO Arbutin results in decreased expression of PRKX mRNA CTD PMID:17103032 NCBI chr  X:41,823,349...41,866,844
Ensembl chr  X:41,823,355...41,866,669 		JBrowse link
G Prmt2 protein arginine methyltransferase 2 decreases expression ISO Arbutin results in decreased expression of PRMT2 mRNA CTD PMID:17103032 NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643 		JBrowse link
G Prr18 proline rich 18 decreases expression ISO Arbutin results in decreased expression of PRR18 mRNA CTD PMID:17103032 NCBI chr 1:52,400,215...52,403,998
Ensembl chr 1:52,400,215...52,404,309 		JBrowse link
G Prrx1 paired related homeobox 1 decreases expression ISO Arbutin results in decreased expression of PRRX1 mRNA CTD PMID:17103032 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866 		JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 decreases expression ISO Arbutin results in decreased expression of PSMD13 mRNA CTD PMID:17103032 NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905 		JBrowse link
G Psmd3 proteasome 26S subunit, non-ATPase 3 decreases expression ISO Arbutin results in decreased expression of PSMD3 mRNA CTD PMID:17103032 NCBI chr10:83,643,473...83,655,620
Ensembl chr10:83,643,647...83,655,618 		JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 increases expression ISO Arbutin results in increased expression of RAB3GAP1 mRNA CTD PMID:17103032 NCBI chr13:39,355,698...39,429,154
Ensembl chr13:39,352,247...39,429,169 		JBrowse link
G Rab6b RAB6B, member RAS oncogene family decreases expression ISO Arbutin results in decreased expression of RAB6B mRNA CTD PMID:17103032 NCBI chr 8:103,695,328...103,764,023
Ensembl chr 8:103,695,631...103,805,732 		JBrowse link
G Rasgef1b RasGEF domain family, member 1B decreases expression ISO Arbutin results in decreased expression of RASGEF1B mRNA CTD PMID:17103032 NCBI chr14:9,859,512...10,380,044
Ensembl chr14:9,860,247...10,379,741 		JBrowse link
G Rnf208 ring finger protein 208 decreases expression ISO Arbutin results in decreased expression of RNF208 mRNA CTD PMID:17103032 NCBI chr 3:8,057,808...8,059,721
Ensembl chr 3:8,043,685...8,059,844 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression ISO Arbutin results in increased expression of RPS6KA3 mRNA CTD PMID:17103032 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207 		JBrowse link
G Rsbn1 round spermatid basic protein 1 decreases expression ISO Arbutin results in decreased expression of RSBN1 mRNA CTD PMID:17103032 NCBI chr 2:191,416,631...191,470,711
Ensembl chr 2:191,416,631...191,470,711 		JBrowse link
G Saa4 serum amyloid A4 decreases expression ISO Arbutin results in decreased expression of SAA4 mRNA CTD PMID:17103032 NCBI chr 1:97,247,580...97,251,882 JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) increases expression ISO Arbutin results in increased expression of SCCPDH mRNA CTD PMID:17103032 NCBI chr13:91,400,120...91,421,875
Ensembl chr13:91,400,190...91,422,222 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 increases expression ISO Arbutin results in increased expression of SCN1B mRNA CTD PMID:17103032 NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Sdc4 syndecan 4 decreases expression ISO Arbutin results in decreased expression of SDC4 mRNA CTD PMID:17103032 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Semg1 semenogelin 1 decreases expression ISO Arbutin results in decreased expression of SEMG1 mRNA CTD PMID:17103032 NCBI chr 3:152,910,033...152,912,882
Ensembl chr 3:152,910,034...152,912,882 		JBrowse link
G Serpina5 serpin family A member 5 decreases expression ISO Arbutin results in decreased expression of SERPINA5 mRNA CTD PMID:17103032 NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:123,023,306...123,028,407 		JBrowse link
G Serpind1 serpin family D member 1 decreases expression ISO Arbutin results in decreased expression of SERPIND1 mRNA CTD PMID:17103032 NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 increases expression ISO Arbutin results in increased expression of SF3B1 mRNA CTD PMID:17103032 NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300 		JBrowse link
G Sfrp5 secreted frizzled-related protein 5 decreases expression ISO Arbutin results in decreased expression of SFRP5 mRNA CTD PMID:17103032 NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:241,006,762...241,011,224 		JBrowse link
G Sfxn2 sideroflexin 2 decreases expression ISO Arbutin results in decreased expression of SFXN2 mRNA CTD PMID:17103032 NCBI chr 1:245,447,014...245,459,312
Ensembl chr 1:245,447,015...245,468,411
Ensembl chr 1:245,447,015...245,468,411 		JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 decreases expression ISO Arbutin results in decreased expression of SH3GL2 mRNA CTD PMID:17103032 NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843 		JBrowse link
G Sin3b SIN3 transcription regulator family member B decreases expression ISO Arbutin results in decreased expression of SIN3B mRNA CTD PMID:17103032 NCBI chr16:17,123,277...17,159,978
Ensembl chr16:17,123,434...17,159,978 		JBrowse link
G Slc13a2 solute carrier family 13 member 2 decreases expression ISO Arbutin results in decreased expression of SLC13A2 mRNA CTD PMID:17103032 NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 decreases expression ISO Arbutin results in decreased expression of SLC15A3 mRNA CTD PMID:17103032 NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 decreases expression ISO Arbutin results in decreased expression of SLC18A2 mRNA CTD PMID:17103032 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc23a3 solute carrier family 23, member 3 increases expression ISO Arbutin results in increased expression of SLC23A3 mRNA CTD PMID:17103032 NCBI chr 9:76,622,621...76,633,188
Ensembl chr 9:76,622,800...76,631,366 		JBrowse link
G Slc25a2 solute carrier family 25 member 2 decreases expression ISO Arbutin results in decreased expression of SLC25A2 mRNA CTD PMID:17103032 NCBI chr18:29,452,943...29,456,324
Ensembl chr18:29,453,582...29,460,383 		JBrowse link
G Slc27a4 solute carrier family 27 member 4 decreases expression ISO Arbutin results in decreased expression of SLC27A4 mRNA CTD PMID:17103032 NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943 		JBrowse link
G Slc7a3 solute carrier family 7 member 3 decreases expression ISO Arbutin results in decreased expression of SLC7A3 mRNA CTD PMID:17103032 NCBI chr  X:66,210,071...66,216,482
Ensembl chr  X:66,210,081...66,215,708 		JBrowse link
G Slco5a1 solute carrier organic anion transporter family, member 5A1 decreases expression ISO Arbutin results in decreased expression of SLCO5A1 mRNA CTD PMID:17103032 NCBI chr 5:6,228,938...6,358,124
Ensembl chr 5:6,228,973...6,352,913 		JBrowse link
G Snip1 Smad nuclear interacting protein 1 decreases expression ISO Arbutin results in decreased expression of SNIP1 mRNA CTD PMID:17103032 NCBI chr 5:137,328,371...137,335,846
Ensembl chr 5:137,328,371...137,335,845 		JBrowse link
G Socs4 suppressor of cytokine signaling 4 decreases expression ISO Arbutin results in decreased expression of SOCS4 mRNA CTD PMID:17103032 NCBI chr15:20,523,406...20,537,889
Ensembl chr15:20,523,183...20,542,494 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Arbutin inhibits the reaction [potassium bromate results in decreased activity of SOD1 protein] CTD PMID:36284482 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Spata13 spermatogenesis associated 13 increases expression ISO Arbutin results in increased expression of SPATA13 mRNA CTD PMID:17103032 NCBI chr15:34,778,479...34,907,645
Ensembl chr15:34,778,473...34,905,114 		JBrowse link
G Spata20 spermatogenesis associated 20 decreases expression ISO Arbutin results in decreased expression of SPATA20 mRNA CTD PMID:17103032 NCBI chr10:79,427,525...79,435,472
Ensembl chr10:79,427,528...79,434,368 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 increases expression ISO Arbutin results in increased expression of SPTLC1 mRNA CTD PMID:17103032 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases activity
decreases expression		 EXP Arbutin results in decreased activity of SRD5A1 protein
Arbutin results in decreased expression of SRD5A1 mRNA; Arbutin results in decreased expression of SRD5A1 protein		 CTD PMID:37783241 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Stard8 StAR-related lipid transfer domain containing 8 decreases expression ISO Arbutin results in decreased expression of STARD8 mRNA CTD PMID:17103032 NCBI chr  X:64,079,079...64,196,052
Ensembl chr  X:64,124,574...64,196,052 		JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 decreases expression ISO Arbutin results in decreased expression of SYDE1 mRNA CTD PMID:17103032 NCBI chr 7:11,032,931...11,038,917
Ensembl chr 7:11,032,898...11,039,869 		JBrowse link
G Sympk symplekin scaffold protein decreases expression ISO Arbutin results in decreased expression of SYMPK mRNA CTD PMID:17103032 NCBI chr 1:78,672,372...78,700,684
Ensembl chr 1:78,672,378...78,700,684 		JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor decreases expression ISO Arbutin results in decreased expression of TAL1 mRNA CTD PMID:17103032 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976 		JBrowse link
G Tardbp TAR DNA binding protein increases expression ISO Arbutin results in increased expression of TARDBP mRNA CTD PMID:17103032 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055 		JBrowse link
G Tcf12 transcription factor 12 increases expression ISO Arbutin results in increased expression of TCF12 mRNA CTD PMID:17103032 NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:72,492,567...72,799,201 		JBrowse link
G Tes testin LIM domain protein increases expression ISO Arbutin results in increased expression of TES mRNA CTD PMID:17103032 NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829 		JBrowse link
G Tex13b testis expressed 13B decreases expression ISO Arbutin results in decreased expression of TEX13B mRNA CTD PMID:17103032 NCBI chr  X:104,490,937...104,511,224
Ensembl chr  X:104,490,091...104,494,201 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 decreases expression ISO Arbutin results in decreased expression of TGFB3 mRNA CTD PMID:17103032 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tll1 tolloid-like 1 decreases expression ISO Arbutin results in decreased expression of TLL1 mRNA CTD PMID:17103032 NCBI chr16:25,509,146...25,710,330
Ensembl chr16:25,509,146...25,709,543 		JBrowse link
G Tmem59l transmembrane protein 59-like decreases expression ISO Arbutin results in decreased expression of TMEM59L mRNA CTD PMID:17103032 NCBI chr16:18,941,370...18,945,381
Ensembl chr16:18,941,567...18,945,381 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Arbutin inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:34346143 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tor4a torsin family 4, member A decreases expression ISO Arbutin results in decreased expression of TOR4A mRNA CTD PMID:17103032 NCBI chr 3:8,004,292...8,007,979
Ensembl chr 3:8,002,023...8,008,042 		JBrowse link
G Tram2 translocation associated membrane protein 2 decreases expression ISO Arbutin results in decreased expression of TRAM2 mRNA CTD PMID:17103032 NCBI chr 9:23,419,204...23,498,745
Ensembl chr 9:23,424,232...23,498,689 		JBrowse link
G Treh trehalase decreases expression ISO Arbutin results in decreased expression of TREH mRNA CTD PMID:17103032 NCBI chr 8:44,990,182...45,003,881
Ensembl chr 8:44,990,182...45,003,540 		JBrowse link
G Tsc1 TSC complex subunit 1 increases expression ISO Arbutin results in increased expression of TSC1 mRNA CTD PMID:17103032 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Tsc22d2 TSC22 domain family, member 2 decreases expression ISO Arbutin results in decreased expression of TSC22D2 mRNA CTD PMID:17103032 NCBI chr 2:142,646,778...142,697,977
Ensembl chr 2:142,644,744...142,693,606 		JBrowse link
G Tshz2 teashirt zinc finger homeobox 2 decreases expression ISO Arbutin results in decreased expression of TSHZ2 mRNA CTD PMID:17103032 NCBI chr 3:158,405,469...158,666,915
Ensembl chr 3:158,405,423...158,850,128 		JBrowse link
G Tspoap1 TSPO associated protein 1 decreases expression ISO Arbutin results in decreased expression of TSPOAP1 mRNA CTD PMID:17103032 NCBI chr10:72,554,220...72,586,402
Ensembl chr10:72,560,980...72,586,412 		JBrowse link
G Ttc22 tetratricopeptide repeat domain 22 decreases expression ISO Arbutin results in decreased expression of TTC22 mRNA CTD PMID:17103032 NCBI chr 5:121,401,973...121,423,130
Ensembl chr 5:121,406,326...121,423,130 		JBrowse link
G Tulp3 TUB like protein 3 decreases expression ISO Arbutin results in decreased expression of TULP3 mRNA CTD PMID:17103032 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
G Tyr tyrosinase decreases expression
decreases activity		 ISO Arbutin results in decreased expression of TYR mRNA
Arbutin results in decreased activity of TYR protein		 CTD PMID:21071833 PMID:22705713 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
G Ube2d2b ubiquitin-conjugating enzyme E2D 2B decreases expression ISO Arbutin results in decreased expression of UBE2D4 mRNA CTD PMID:17103032 NCBI chr14:1,915,999...1,917,473
Ensembl chr14:1,916,845...1,917,416 		JBrowse link
G Ube2m ubiquitin-conjugating enzyme E2M decreases expression ISO Arbutin results in decreased expression of UBE2M mRNA CTD PMID:17103032 NCBI chr 1:73,662,576...73,666,113
Ensembl chr 1:73,662,576...73,666,026 		JBrowse link
G Ubqln1 ubiquilin 1 increases expression ISO Arbutin results in increased expression of UBQLN1 mRNA CTD PMID:17103032 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 decreases expression ISO Arbutin results in decreased expression of USP44 mRNA CTD PMID:17103032 NCBI chr 7:28,364,169...28,412,039
Ensembl chr 7:28,364,033...28,410,053 		JBrowse link
G Utp11 UTP11, small subunit processome component increases expression ISO Arbutin results in increased expression of UTP11 mRNA CTD PMID:17103032 NCBI chr 5:136,931,279...136,946,164
Ensembl chr 5:136,931,008...136,946,191 		JBrowse link
G Vps13b vacuolar protein sorting 13 homolog B decreases expression ISO Arbutin results in decreased expression of VPS13B mRNA CTD PMID:17103032 NCBI chr 7:66,557,862...67,128,429
Ensembl chr 7:66,558,471...67,128,429 		JBrowse link
G Vps39 VPS39 subunit of HOPS complex increases expression ISO Arbutin results in increased expression of VPS39 mRNA CTD PMID:17103032 NCBI chr 3:107,266,846...107,304,884
Ensembl chr 3:107,267,310...107,304,975 		JBrowse link
G Vwa3a von Willebrand factor A domain containing 3A decreases expression ISO Arbutin results in decreased expression of VWA3A mRNA CTD PMID:17103032 NCBI chr 1:175,293,782...175,355,588
Ensembl chr 1:175,293,873...175,355,602 		JBrowse link
G Wnt10a Wnt family member 10A decreases expression ISO Arbutin results in decreased expression of WNT10A mRNA CTD PMID:17103032 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400 		JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 increases expression ISO Arbutin results in increased expression of ZBTB20 mRNA CTD PMID:17103032 NCBI chr11:57,052,129...57,791,214
Ensembl chr11:57,072,880...57,510,210 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B decreases expression ISO Arbutin results in decreased expression of ZBTB7B mRNA CTD PMID:17103032 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
G Zdhhc2 zinc finger DHHC-type palmitoyltransferase 2 decreases expression ISO Arbutin results in decreased expression of ZDHHC2 mRNA CTD PMID:17103032 NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060 		JBrowse link
G Zfp414 zinc finger protein 414 decreases expression ISO Arbutin results in decreased expression of ZNF414 mRNA CTD PMID:17103032 NCBI chr 7:14,420,232...14,422,939
Ensembl chr 7:14,420,165...14,438,166 		JBrowse link
G Zfp483 zinc finger protein 483 decreases expression ISO Arbutin results in decreased expression of ZNF483 mRNA CTD PMID:17103032 NCBI chr 5:73,763,201...73,780,511
Ensembl chr 5:73,763,179...73,776,223 		JBrowse link
G Zfp870 zinc finger protein 870 increases expression ISO Arbutin results in increased expression of ZNF670 mRNA CTD PMID:17103032 NCBI chr 7:11,990,146...12,003,813
Ensembl chr 7:11,990,148...12,003,813 		JBrowse link
G Zkscan7 zinc finger with KRAB and SCAN domains 7 decreases expression ISO Arbutin results in decreased expression of ZKSCAN7 mRNA CTD PMID:17103032 NCBI chr 8:122,501,938...122,519,600
Ensembl chr 8:122,502,218...122,519,600 		JBrowse link
G Znf354b zinc finger protein 354B decreases expression ISO Arbutin results in decreased expression of ZNF354B mRNA CTD PMID:17103032 NCBI chr10:35,233,783...35,251,110
Ensembl chr10:35,185,028...35,245,505 		JBrowse link
G Znf81 zinc finger protein 81 decreases expression ISO Arbutin results in decreased expression of ZNF81 mRNA CTD PMID:17103032 NCBI chr  X:1,030,103...1,126,078
Ensembl chr  X:1,036,153...1,126,102 		JBrowse link
G Zp2 zona pellucida glycoprotein 2 decreases expression ISO Arbutin results in decreased expression of ZP2 mRNA CTD PMID:17103032 NCBI chr 1:174,513,507...174,525,288
Ensembl chr 1:174,513,511...174,525,288 		JBrowse link
monobenzone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP monobenzone binds to AFP protein CTD PMID:23013281 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Ar androgen receptor affects binding EXP monobenzone binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [monobenzone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:25455453 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions		 ISO monobenzone results in increased activity of NR1I2 protein
[monobenzone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA		 CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO monobenzone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO monobenzone affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
tetrachlorohydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO 2,3,5,6-tetrachlorohydroquinone results in decreased activity of ACHE protein CTD PMID:30905860 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Ar androgen receptor multiple interactions ISO 2,3,5,6-tetrachlorohydroquinone inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 2,3,5,6-tetrachlorohydroquinone results in decreased expression of BCL2 protein CTD PMID:11064002 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity ISO 2,3,5,6-tetrachlorohydroquinone results in increased activity of CASP3 protein CTD PMID:30905860 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cse1l chromosome segregation 1 like decreases expression ISO 2,3,5,6-tetrachlorohydroquinone results in decreased expression of CSE1L protein CTD PMID:11064002 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO 2,3,5,6-tetrachlorohydroquinone results in increased expression of PCNA protein CTD PMID:12669308 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 multiple interactions ISO TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine] CTD PMID:24214992 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 multiple interactions ISO TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine] CTD PMID:24214992 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2,3,5,6-tetrachlorohydroquinone results in increased expression of TNF mRNA CTD PMID:12669308 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ttr transthyretin affects binding EXP 2,3,5,6-tetrachlorohydroquinone binds to TTR protein CTD PMID:2043046 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      chemical role 19445
        antioxidant 16147
          hydroquinone 1002
            2,5-dihydroxybenzenesulfonic acid 0
            2,6-dibromohydroquinone 0
            4-hydroxyphenyl acetate 0
            chlorohydroquinones + 10
            gentisyl alcohol 0
            hydroquinone O-beta-D-glucopyranoside + 278
            monobenzone 6
            quinhydrone 0
            quinol sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19731
                        carbon atom 19727
                          organic molecular entity 19727
                            organic molecule 19680
                              organic cyclic compound 19493
                                organic aromatic compound 19360
                                  phenols 18633
                                    benzenediols 9148
                                      benzenediol 1169
                                        hydroquinone 1002
                                          2,5-dihydroxybenzenesulfonic acid 0
                                          2,6-dibromohydroquinone 0
                                          4-hydroxyphenyl acetate 0
                                          chlorohydroquinones + 10
                                          gentisyl alcohol 0
                                          hydroquinone O-beta-D-glucopyranoside + 278
                                          monobenzone 6
                                          quinhydrone 0
                                          quinol sulfate 0
paths to the root