Gene: Cyp1b1 (cytochrome P450, family 1, subfamily b, polypeptide 1)  Rattus norvegicus

Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Description: ENCODES a protein that exhibits oxidoreductase activity; heme binding (ortholog); oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (ortholog); INVOLVED IN cellular aromatic compound metabolic process; estrogen metabolic process; response to organic substance; PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; steroid hormone biosynthetic pathway; tryptophan metabolic pathway; ASSOCIATED WITH Glaucoma (ortholog); Glaucoma 1, Open Angle, A (ortholog); Glaucoma 3, Primary Congenital, A (ortholog); FOUND IN intracellular membrane-bounded organelle; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CYPIB1; Cytochrome P450 1b1; cytochrome P450 1B1; cytochrome P450, subfamily 1B, polypeptide 1; cytochrome P450RAP; P450RAP
Orthologs: Homo sapiens : CYP1B1 (cytochrome P450, family 1, subfamily B, polypeptide 1)  HGNC
Mus musculus : Cyp1b1 (cytochrome P450, family 1, subfamily b, polypeptide 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map6q11 NCBI
RGSC Genome Assembly v5.062,294,952 - 2,300,644-NCBI
RGSC Genome Assembly v3.462,548,224 - 2,553,767-NCBI
Rat Celera Assembly615,009,941 - 15,015,671+NCBI
Genome Assembly 3.162,545,648 - 2,553,767-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp1b1
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RGD Object Information
RGD ID: 2460
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE