Gene: Brca1 (breast cancer 1, early onset) Rattus norvegicus
Symbol: Brca1
Name: breast cancer 1, early onset
Description: ENCODES a protein that exhibits damaged DNA binding (ortholog); enzyme binding (ortholog); RNA binding (ortholog); INVOLVED IN brain development; response to estradiol; response to lipid; PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; forkhead class A signaling pathway; homologous recombination pathway of double-strand break repair; ASSOCIATED WITH Hypertension; Mammary Neoplasms, Experimental; Breast Neoplasms (ortholog); FOUND IN mitochondrial matrix; BRCA1-A complex (ortholog); BRCA1-BARD1 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: breast cancer 1; breast cancer type 1 susceptibility protein homolog
Orthologs:
Allele / Splice: Brca1m1Uwm  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.01089,394,821 - 89,455,009-NCBI
Rat Cytogenetic Map10q32.1 NCBI
RGSC Genome Assembly v5.01089,192,653 - 89,252,760-NCBI
RGSC Genome Assembly v3.41090,513,630 - 90,572,676-NCBI
Rat Celera Assembly1085,140,052 - 85,200,670-NCBI
Genome Assembly 3.11090,527,999 - 90,587,046-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)
Related Rat Strains

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Brca1
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2218
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-09-10
Status: ACTIVE