Brca1 (breast cancer 1, early onset)

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Keyword

Gene: Brca1 (breast cancer 1, early onset) Rattus norvegicus

Symbol:

Brca1

Name:

breast cancer 1, early onset

Description:

ENCODES a protein that exhibits damaged DNA binding (ortholog); enzyme binding (ortholog); RNA binding (ortholog); INVOLVED IN brain development; response to estradiol stimulus; response to lipid; PARTICIPATES IN forkhead class A signaling pathway; homologous recombination pathway of double-strand break repair; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Mammary Neoplasms, Experimental; Breast Neoplasms (ortholog); BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 (ortholog); FOUND IN mitochondrial matrix; BRCA1-A complex (ortholog); BRCA1-BARD1 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; ammonium chloride

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

breast cancer 1; breast cancer type 1 susceptibility protein homolog

Orthologs:

Homo sapiens : BRCA1 (breast cancer 1, early onset) HGNC
Mus musculus : Brca1 (breast cancer 1) MGI

Allele / Splice:

Brca1^m1Uwm

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	10	q32.1		NCBI
RGSC Genome Assembly v5.0	10	89,193,680 - 89,252,502	-	NCBI
RGSC Genome Assembly v3.4	10	90,513,630 - 90,572,676	-	NCBI
Rat Celera Assembly	10	85,140,052 - 85,200,670	-	NCBI
Genome Assembly 3.1	10	90,527,999 - 90,587,046	-	NCBI