GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a1 | affects response to substance | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | CYP1A1 protein affects the susceptibility to hydroquinone | PMID:8242868 | Cyp1a1 | increases expression | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | hydroquinone results in increased expression of CYP1A1 mRNA; hydroquinone results in increased expression of CYP1A1 protein | PMID:23416264 PMID:31256213 PMID:35123993 | Cyp1a1 | multiple interactions | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein] | PMID:35123993 | | ||||||||||||||||||||||
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