Gene: Lmna (lamin A/C) Rattus norvegicus
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Symbol: Lmna
Name: lamin A/C
Description: ENCODES a protein that exhibits protein phosphatase 1 binding; identical protein binding (ortholog); INVOLVED IN cellular senescence; negative regulation of adipose tissue development; positive regulation of osteoblast differentiation; PARTICIPATES IN atherosclerosis pathway; arrhythmogenic right ventricular cardiomyopathy pathway; dilated cardiomyopathy pathway; ASSOCIATED WITH Arteriosclerosis; Ischemic Attack, Transient; Aortic Valve Disease 2 (ortholog); FOUND IN nuclear matrix; nucleus; extracellular matrix (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: lamin A; lamin C2; lamin-A; prelamin-A/C
Orthologs:
Homo sapiens (human) : LMNA (lamin A/C)  HGNC  AGR
Mus musculus (house mouse) : Lmna (lamin A)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Lmna (lamin A/C)
Pan paniscus (bonobo/pygmy chimpanzee) : LMNA (lamin A/C)
Canis lupus familiaris (dog) : LMNA (lamin A/C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lmna (lamin A/C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02187,842,884 - 187,863,552 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02207,245,237 - 207,265,928 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,595,724 - 180,616,354 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12180,545,829 - 180,566,460 (-)NCBI
Celera2167,884,341 - 167,905,010 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lmna
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620456
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE