Gene: Casp1 (caspase 1) Rattus norvegicus
Symbol: Casp1
Name: caspase 1
Description: ENCODES a protein that exhibits scaffold protein binding; cysteine-type endopeptidase activity (ortholog); endopeptidase activity (ortholog); INVOLVED IN apoptotic process; lung development; memory; PARTICIPATES IN interleukin-1 signaling pathway; type II interferon signaling pathway; amyotrophic lateral sclerosis disease pathway; ASSOCIATED WITH Acute Kidney Injury; Brain Injuries; Diabetes Mellitus, Experimental; FOUND IN cytoplasm; neuron projection; nucleus; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
Also known as: CASP-1; caspase 1 apoptosis-related cysteine protease (interleukin 1 beta convertase); caspase-1; Ice; IL-1 beta-converting enzyme; IL-1BC; Il1bc; interleukin 1 beta convertase; interleukin 1, beta, convertase; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; p45
Homo sapiens : CASP1 (caspase 1)  HGNC
Mus musculus : Casp1 (caspase 1)  MGI
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.082,605,743 - 2,614,637 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.082,627,976 - 2,636,870 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.482,027,976 - 2,036,872 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.182,027,975 - 2,036,866 (+)NCBI
Celera82,455,483 - 2,464,376 (+)NCBI
Cytogenetic Map8q11NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Casp1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 2274
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-09-13
Status: ACTIVE