Gene: Casp1 (caspase 1) Rattus norvegicus
Symbol: Casp1
Name: caspase 1
Description: ENCODES a protein that exhibits scaffold protein binding; cysteine-type endopeptidase activity (ortholog); endopeptidase activity (ortholog); INVOLVED IN apoptotic process; lung development; memory; PARTICIPATES IN interleukin-1 signaling pathway; type II interferon signaling pathway; amyotrophic lateral sclerosis disease pathway; ASSOCIATED WITH Acute Kidney Injury; Brain Injuries; Diabetes Mellitus, Experimental; FOUND IN cytoplasm; neuron projection; nucleus; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CASP-1; caspase 1 apoptosis-related cysteine protease (interleukin 1 beta convertase); caspase-1; Ice; IL-1 beta-converting enzyme; IL-1BC; Il1bc; interleukin 1 beta convertase; interleukin 1, beta, convertase; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; p45
Orthologs:
Homo sapiens : CASP1 (caspase 1)  HGNC
Mus musculus : Casp1 (caspase 1)  MGI
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.082,605,743 - 2,614,637 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.082,627,976 - 2,636,870 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.482,027,976 - 2,036,872 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.182,027,975 - 2,036,866 (+)NCBI
Celera82,455,483 - 2,464,376 (+)NCBI
Cytogenetic Map8q11NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Casp1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2274
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-09-13
Status: ACTIVE