The Pathway Interaction Database (PID) Annotation Import Pipeline
Data is imported from the Pathway Interaction Database (PID - http://pid.nci.nih.gov/). Data is extracted from the file “NCI-Nature Curated Pathway – UniProt mapping”. The internal PID ID in the file are searched for mapping to pathway term in the Pathway Ontology (PW) via related_synonym. Genes are then matched to RGD human genes using the UniProt gene ID. The human genes are assigned to PW term with evidence code EXP or “inferred from experimental evidence” and the annotations are propagated to the rat and mouse orthologs with evidence code “ISO” or “inferred from sequence orthology”.