RGD Reference Report - PID Annotation Import Pipeline

Keyword

PID Annotation Import Pipeline
Authors:	PIPELINES RGD, AUTOMATED
Citation:	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
Web Url:	http://pid.nci.nih.gov/download.shtml
The Pathway Interaction Database (PID) Annotation Import Pipeline Data is imported from the Pathway Interaction Database (PID - http://pid.nci.nih.gov/). Data is extracted from the file “NCI-Nature Curated Pathway – UniProt mapping”. The internal PID ID in the file are searched for mapping to pathway term in the Pathway Ontology (PW) via related_synonym. Genes are then matched to RGD human genes using the UniProt gene ID. The human genes are assigned to PW term with evidence code EXP or “inferred from experimental evidence” and the annotations are propagated to the rat and mouse orthologs with evidence code “ISO” or “inferred from sequence orthology”.