Gene: Il12b (interleukin 12B) Rattus norvegicus
Symbol: Il12b
Name: interleukin 12B
Description: ENCODES a protein that exhibits interleukin-12 alpha subunit binding; protein heterodimerization activity; cytokine activity (ortholog); INVOLVED IN natural killer cell activation involved in immune response; sensory perception of pain; cell cycle arrest (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; interleukin-27 signaling pathway; ASSOCIATED WITH Encephalomyelitis, Autoimmune, Experimental; Sepsis; Asthma (ortholog); FOUND IN extracellular space; interleukin-12 complex; cytoplasm (ortholog); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
Also known as: Il12; Interleukin 12; interleukin-12 p40; interleukin-12 p40 precursor; interleukin-12 subunit beta
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01030,034,453 - 30,048,120+NCBI
Rat Cytogenetic Map10q21 NCBI
RGSC Genome Assembly v5.01029,868,367 - 29,882,535+NCBI
RGSC Genome Assembly v3.41029,558,955 - 29,568,331+NCBI
Rat Celera Assembly1028,372,232 - 28,381,601+NCBI
Genome Assembly 3.11029,560,003 - 29,569,378+NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Il12b
Entrez Gene
Ensembl Gene
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Vista + UCSC

RGD Object Information
RGD ID: 628704
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE