Map2k1 (mitogen activated protein kinase kinase 1)

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Keyword

Gene: Map2k1 (mitogen activated protein kinase kinase 1) Rattus norvegicus

Symbol:

Map2k1

Name:

mitogen activated protein kinase kinase 1

Description:

ENCODES a protein that exhibits ATP binding; MAP kinase kinase activity; mitogen-activated protein kinase kinase kinase binding; INVOLVED IN activation of MAPK activity; cell proliferation; Golgi inheritance; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; ceramide signaling pathway; ASSOCIATED WITH impaired smooth muscle contractility; ASSOCIATED WITH Liver Neoplasms, Experimental; Prostatic Neoplasms; Brain Ischemia (ortholog); FOUND IN axon part; cell cortex; cytosol; INTERACTS WITH 17alpha-ethynylestradiol; 2,6-dinitrotoluene; 2-arachidonoylglycerol

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

dual specificity mitogen-activated protein kinase kinase 1; ERK activator kinase 1; MAP kinase kinase 1; MAP kinase/Erk kinase 1; MAPK/ERK kinase 1; MAPKK 1; Mek1; mitogen-activated protein kinase kinase 1

Orthologs:

Homo sapiens : MAP2K1 (mitogen-activated protein kinase kinase 1) HGNC
Mus musculus : Map2k1 (mitogen-activated protein kinase kinase 1) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	8	q24		NCBI
RGSC Genome Assembly v5.0	8	68,840,454 - 68,877,679	-	NCBI
RGSC Genome Assembly v3.4	8	68,379,074 - 68,451,554	-	NCBI
Rat Celera Assembly	8	64,090,188 - 64,161,314	-	NCBI
Genome Assembly 3.1	8	68,398,125 - 68,470,608	-	NCBI