Gene: Keap1 (Kelch-like ECH-associated protein 1) Rattus norvegicus
Symbol: Keap1
Name: Kelch-like ECH-associated protein 1
Description: ENCODES a protein that exhibits transcription factor binding (ortholog); INVOLVED IN cellular response to organic cyclic compound; cytoplasmic sequestering of transcription factor; negative regulation of gene expression; PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Diabetic Nephropathies; Diabetic Retinopathy; Kidney Failure, Chronic; FOUND IN cell-cell adherens junction; cytoplasm; focal adhesion; INTERACTS WITH 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene; 7,12-dimethyltetraphene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cytosolic inhibitor of Nrf2; Inrf2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0822,250,518 - 22,259,868 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0822,305,765 - 22,315,026 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4820,259,178 - 20,266,351 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1820,259,177 - 20,266,352 (-)NCBI
Celera821,161,976 - 21,171,435 (-)NCBI
Cytogenetic Map8q13NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Keap1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 621619
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-20
Status: ACTIVE