Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Ccar1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of CCAR1 mRNA | CTD | PMID:22206623 | 1,3-dinitrobenzene | decreases expression | EXP | | 6480464 | 3-dinitrobenzene results in decreased expression of CCAR1 mRNA | CTD | PMID:21983209 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Ccar1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ccar1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CCAR1 mRNA | CTD | PMID:21570461 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CCAR1 mRNA | CTD | PMID:22504374 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CCAR1 mRNA | CTD | PMID:30047161 | aflatoxin B1 | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of CCAR1 mRNA | CTD | PMID:19770486 | Aroclor 1254 | decreases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of CCAR1 mRNA | CTD | PMID:23650126 | benzatropine | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Benztropine results in increased expression of CCAR1 protein | CTD | PMID:34122009 | benzo[a]pyrene | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of CCAR1 mRNA | CTD | PMID:22228805 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CCAR1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Ccar1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of CCAR1 mRNA | CTD | PMID:33221593 | bortezomib | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of CCAR1 protein | CTD | PMID:21594647 and PMID:21903591 | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of CCAR1 protein | CTD | PMID:28903499 | cadmium atom | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CCAR1 mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of CCAR1 mRNA | CTD | PMID:21297351 | cadmium dichloride | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CCAR1 mRNA | CTD | PMID:35301059 | caffeine | affects phosphorylation | ISO | CCAR1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of CCAR1 protein | CTD | PMID:35688186 | cannabidiol | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Cannabidiol results in increased expression of CCAR1 protein | CTD | PMID:34122009 | carbon nanotube | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of CCAR1 mRNA | CTD | PMID:25620056 | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of CCAR1 mRNA | CTD | PMID:23125180 | chlorpyrifos | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of CCAR1 mRNA | CTD | PMID:20350560 | cisplatin | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Cisplatin results in increased expression of CCAR1 mRNA | CTD | PMID:21151649 | clozapine | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Clozapine results in increased expression of CCAR1 protein | CTD | PMID:34122009 | copper atom | multiple interactions | ISO | Ccar1 (Mus musculus) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of CCAR1 protein | CTD | PMID:24690739 | copper atom | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of CCAR1 protein | CTD | PMID:24690739 | copper(0) | multiple interactions | ISO | Ccar1 (Mus musculus) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of CCAR1 protein | CTD | PMID:24690739 | copper(0) | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of CCAR1 protein | CTD | PMID:24690739 | curcumin | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Curcumin results in increased expression of CCAR1 protein | CTD | PMID:21594647 | curcumin | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Curcumin results in increased expression of CCAR1 protein | CTD | PMID:21594647 | cypermethrin | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | cypermethrin results in increased expression of CCAR1 protein | CTD | PMID:36063984 | dexamethasone | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Dexamethasone results in increased expression of CCAR1 mRNA | CTD | PMID:17998272 | dibutyl phthalate | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of CCAR1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of CCAR1 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of CCAR1 mRNA | CTD | PMID:28302478 | disulfiram | multiple interactions | ISO | Ccar1 (Mus musculus) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of CCAR1 protein | CTD | PMID:24690739 | disulfiram | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of CCAR1 protein | CTD | PMID:24690739 | dorsomorphin | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCAR1 mRNA | CTD | PMID:27188386 | doxorubicin | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [Doxorubicin co-treated with JNK-IN-8] results in increased expression of CCAR1 protein more ... | CTD | PMID:21903591 more ... | doxorubicin | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of CCAR1 protein | CTD | PMID:23826121 and PMID:30769864 | emetine | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | Emetine inhibits the reaction [sodium arsenite affects the localization of CCAR1 protein] | CTD | PMID:19073175 | enzyme inhibitor | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CCAR1 protein | CTD | PMID:23301498 | ethanol | affects expression | ISO | Ccar1 (Mus musculus) | 6480464 | Ethanol affects the expression of CCAR1 mRNA | CTD | PMID:30319688 | FR900359 | increases phosphorylation | ISO | CCAR1 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of CCAR1 protein | CTD | PMID:37730182 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of CCAR1 mRNA | CTD | PMID:33387578 | hydroquinone O-beta-D-glucopyranoside | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Arbutin results in increased expression of CCAR1 mRNA | CTD | PMID:17103032 | ivermectin | decreases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of CCAR1 protein | CTD | PMID:32959892 | kojic acid | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | kojic acid results in increased expression of CCAR1 mRNA | CTD | PMID:16595896 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of CCAR1 mRNA | CTD | PMID:30467583 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of CCAR1 mRNA | CTD | PMID:22504374 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of CCAR1 mRNA | CTD | PMID:30047161 | methylmercury chloride | decreases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of CCAR1 mRNA | CTD | PMID:28001369 | miconazole | decreases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Miconazole results in decreased expression of CCAR1 mRNA | CTD | PMID:27462272 | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of CCAR1 mRNA | CTD | PMID:19041683 | nocodazole | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | Nocodazole inhibits the reaction [sodium arsenite affects the localization of CCAR1 protein] and Nocodazole promotes the reaction [CCAR1 protein binds to ANAPC2 protein] | CTD | PMID:19073175 and PMID:21903591 | nocodazole | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Nocodazole results in increased expression of CCAR1 protein | CTD | PMID:21903591 | paclitaxel | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Paclitaxel results in increased expression of CCAR1 mRNA | CTD | PMID:18058816 | paracetamol | affects expression | ISO | Ccar1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of CCAR1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CCAR1 mRNA | CTD | PMID:33387578 | perfluorooctanoic acid | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of CCAR1 protein | CTD | PMID:37422089 | perfluorooctanoic acid | decreases expression | ISO | Ccar1 (Mus musculus) | 6480464 | perfluorooctanoic acid results in decreased expression of CCAR1 protein | CTD | PMID:36214631 | phenobarbital | decreases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of CCAR1 mRNA | CTD | PMID:23091169 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of CCAR1 mRNA | CTD | PMID:30047161 | pyrazinecarboxamide | decreases expression | EXP | | 6480464 | Pyrazinamide results in decreased expression of CCAR1 mRNA | CTD | PMID:22431067 | rimonabant | multiple interactions | ISO | Ccar1 (Mus musculus) | 6480464 | Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCAR1 mRNA] | CTD | PMID:19030233 | rotenone | decreases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of CCAR1 mRNA | CTD | PMID:29955902 | SB 431542 | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCAR1 mRNA | CTD | PMID:27188386 | sodium arsenite | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | Emetine inhibits the reaction [sodium arsenite affects the localization of CCAR1 protein] and Nocodazole inhibits the reaction [sodium arsenite affects the localization of CCAR1 protein] | CTD | PMID:19073175 | sodium arsenite | decreases expression | ISO | Ccar1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of CCAR1 mRNA | CTD | PMID:36209798 | sodium arsenite | affects localization | ISO | CCAR1 (Homo sapiens) | 6480464 | sodium arsenite affects the localization of CCAR1 protein | CTD | PMID:19073175 | sulindac sulfide | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | sulindac sulfide results in increased expression of CCAR1 mRNA | CTD | PMID:12734198 | sunitinib | decreases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of CCAR1 mRNA | CTD | PMID:31533062 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of CCAR1 mRNA | CTD | PMID:33387578 | trimellitic anhydride | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of CCAR1 mRNA | CTD | PMID:19042947 | troglitazone | decreases expression | ISO | Ccar1 (Mus musculus) | 6480464 | troglitazone results in decreased expression of CCAR1 mRNA | CTD | PMID:28973697 | tungsten | decreases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of CCAR1 mRNA | CTD | PMID:30912803 | tunicamycin | increases expression | ISO | Ccar1 (Mus musculus) | 6480464 | Tunicamycin results in increased expression of CCAR1 mRNA | CTD | PMID:17127020 | valproic acid | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCAR1 mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CCAR1 mRNA | CTD | PMID:23179753 more ... | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of CCAR1 mRNA | CTD | PMID:19015723 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of CCAR1 mRNA | CTD | PMID:18042343 | vincristine | decreases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of CCAR1 mRNA | CTD | PMID:23649840 | vorinostat | decreases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of CCAR1 mRNA | CTD | PMID:27188386 | |