GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | increases expression | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | hydroquinone results in increased expression of MMP9 mRNA; hydroquinone results in increased expression of MMP9 protein | PMID:26807887 PMID:27515134 PMID:33771647 PMID:33932074 | Mmp9 | increases secretion | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | hydroquinone results in increased secretion of MMP9 protein | PMID:26807887 | Mmp9 | multiple interactions | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; hydroquinone inhibits the reaction [Dicumarol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]]; hydroquinone promotes the reaction [TNF protein results in increased secretion of MMP9 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; PARP1 protein inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein] | PMID:17669387 PMID:26807887 PMID:33771647 PMID:33932074 | |
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