Gene: Gsr (glutathione-disulfide reductase) Rattus norvegicus
Symbol: Gsr
Name: glutathione-disulfide reductase
Description: ENCODES a protein that exhibits flavin adenine dinucleotide binding; glutathione binding; glutathione-disulfide reductase activity; INVOLVED IN aging; glutathione metabolic process; response to activity; PARTICIPATES IN 2-hydroxyglutaricaciduria disease pathway; glutamic acid/glutamate metabolic pathway; glutathione metabolic pathway; ASSOCIATED WITH Acute Kidney Injury; Acute Lung Injury; Alcohol-Induced Disorders; FOUND IN cytosol; mitochondrion; external side of plasma membrane (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (+)-catechin; (+)-sesamin
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glutathione reductase; glutathione reductase, mitochondrial; GR; GRase
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01662,197,617 - 62,239,987 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01661,859,601 - 61,901,971 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41662,255,562 - 62,298,458 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11662,255,636 - 62,298,530 (-)NCBI
Celera1656,518,556 - 56,560,956 (-)NCBI
Cytogenetic Map16q12.3NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gsr
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 621747
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-27
Status: ACTIVE