Arnt (aryl hydrocarbon receptor nuclear translocator) - Rat Genome Database

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Gene: Arnt (aryl hydrocarbon receptor nuclear translocator) Rattus norvegicus
Analyze
Symbol: Arnt
Name: aryl hydrocarbon receptor nuclear translocator
RGD ID: 2153
Description: Contributes to sequence-specific DNA binding activity. Involved in several processes, including G1 to G0 transition; nitric oxide metabolic process; and response to dexamethasone. Predicted to be located in cytoplasm and nuclear body. Predicted to be part of RNA polymerase II transcription regulator complex and nuclear aryl hydrocarbon receptor complex. Predicted to be active in nucleus. Biomarker of hypertension. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator); PARTICIPATES IN aryl hydrocarbon receptor signaling pathway; hypoxia inducible factor pathway; renal cell carcinoma pathway; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Arnt1; Aryl hydrocarbon receptor nuclear translocator 1; dioxin receptor, nuclear translocator; HIF-1 beta; HIF-1-beta; HIF1-beta; hypoxia-inducible factor 1 beta; hypoxia-inducible factor 1-beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,686,703 - 185,745,546 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2185,680,683 - 185,745,546 (+)EnsemblGRCr8
mRatBN7.22182,997,731 - 183,056,584 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,997,736 - 183,056,580 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2190,662,514 - 190,721,330 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02188,458,053 - 188,516,629 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02183,295,003 - 183,353,822 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd2185,290,639 - 185,349,479 (+)NCBI
Lyon_Normotensive2185,517,592 - 185,576,432 (+)NCBI
Lyon_Hypertensive2185,175,158 - 185,233,978 (+)NCBI
F344_StmMcwi2185,270,136 - 185,328,950 (+)NCBI
Rnor_6.02196,594,178 - 196,651,486 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,594,303 - 196,651,179 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.02216,092,481 - 216,150,842 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42190,333,978 - 190,391,015 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2175,530,933 - 175,587,940 (+)NCBICelera
RGSC_v3.12190,296,731 - 190,353,769 (+)NCBI
Cytogenetic Map2q34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,2-naphthoquinone  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
1H-indole  (ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3',4'-dimethoxyflavone  (ISO)
3',5'-cyclic AMP  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP,ISO)
3,3'-diindolylmethane  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-methylcholanthrene  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-vinylcyclohexene dioxide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
7,12-dimethyltetraphene  (EXP)
acrolein  (ISO)
acteoside  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-naphthoflavone  (ISO)
alpha-pinene  (ISO)
Alpinetin  (ISO)
alternariol  (ISO)
amphotericin B  (ISO)
anthracene  (ISO)
apigenin  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (EXP)
atrazine  (ISO)
Azaspiracid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene-7,8-dione  (ISO)
beta-naphthoflavone  (ISO)
betulin  (EXP)
bifenthrin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
captan  (ISO)
carbamazepine  (ISO)
chromium(6+)  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cycloheximide  (ISO)
cyprodinil  (ISO)
D-glucose  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
delphinidin  (ISO)
desferrioxamine B  (EXP,ISO)
dexamethasone  (EXP)
dexlansoprazole  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dicyclanil  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP)
etoposide  (ISO)
fluoranthene  (ISO)
folpet  (ISO)
fulvestrant  (ISO)
galangin  (ISO)
gamma-hexachlorocyclohexane  (EXP)
gemcitabine  (ISO)
genistein  (ISO)
glucose  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indirubin  (EXP,ISO)
indole-3-acetic acid  (ISO)
indole-3-methanol  (ISO)
indoxyl sulfate  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
kaempferol  (ISO)
L-mimosine  (EXP)
lead(0)  (ISO)
linuron  (ISO)
lipopolysaccharide  (ISO)
lycopene  (ISO)
manganese(II) chloride  (ISO)
MeIQx  (ISO)
melatonin  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
mevinphos  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
monoethyl phthalate  (ISO)
N(4)-hydroxycytidine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodiethylamine  (ISO)
naphthalene  (ISO)
nevirapine  (EXP)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP)
Nonidet P-40  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP,ISO)
ozone  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
Pf-06840003  (ISO)
phenanthrene  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
prochloraz  (EXP)
progesterone  (EXP)
pyrene  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
rutin  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
sanguinarine  (ISO)
SB 431542  (ISO)
Sudan III  (ISO)
sulpiride  (EXP)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
tetracycline  (ISO)
theophylline  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
trans-piceid  (ISO)
triptonide  (ISO)
Tryptanthrine  (ISO)
tryptophan  (EXP)
ursodeoxycholic acid  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vanadyl sulfate  (ISO)
vosaroxin  (ISO)
wortmannin  (EXP)
zearalenone  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Targeting renal cell carcinoma with a HIF-2 antagonist. Chen W, etal., Nature. 2016 Nov 3;539(7627):112-117. doi: 10.1038/nature19796. Epub 2016 Sep 5.
2. First evidence of aryl hydrocarbon receptor as a druggable target in hypertension induced by chronic intermittent hypoxia. Coelho NR, etal., Pharmacol Res. 2020 Sep;159:104869. doi: 10.1016/j.phrs.2020.104869. Epub 2020 May 19.
3. Aryl hydrocarbon receptor nuclear translocator (ARNT) gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis. Das SK, etal., BMC Med Genet. 2008 Mar 17;9:16.
4. Cloning and selective expression in brain and kidney of ARNT2 homologous to the Ah receptor nuclear translocator (ARNT). Drutel G, etal., Biochem Biophys Res Commun 1996 Aug 14;225(2):333-9.
5. Two splice variants of the hypoxia-inducible factor HIF-1alpha as potential dimerization partners of ARNT2 in neurons. Drutel G, etal., Eur J Neurosci. 2000 Oct;12(10):3701-8.
6. Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein. Elferink CJ, etal., Mol Pharmacol. 2001 Apr;59(4):664-73.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
9. Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes. Gunton JE, etal., Cell. 2005 Aug 12;122(3):337-49.
10. Maternal Exposure to Bisphenol A Combined with High-Fat Diet-Induced Programmed Hypertension in Adult Male Rat Offspring: Effects of Resveratrol. Hsu CN, etal., Int J Mol Sci. 2019 Sep 6;20(18):4382. doi: 10.3390/ijms20184382.
11. Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor. Hsu CN, etal., Int J Mol Sci. 2020 Jun 26;21(12):4552. doi: 10.3390/ijms21124552.
12. Multiple mechanisms are involved in Ah receptor-mediated cell cycle arrest. Huang G and Elferink CJ, Mol Pharmacol. 2005 Jan;67(1):88-96. doi: 10.1124/mol.104.002410. Epub 2004 Oct 18.
13. Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase. Hunter SR, etal., Drug Metab Dispos. 2017 Feb;45(2):118-129. doi: 10.1124/dmd.116.073833. Epub 2016 Nov 16.
14. HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression. Keith B, etal., Nat Rev Cancer. 2011 Dec 15;12(1):9-22. doi: 10.1038/nrc3183.
15. Identification of novel splice variants of ARNT and ARNT2 in the rat. Korkalainen M, etal., Biochem Biophys Res Commun 2003 Apr 18;303(4):1095-100.
16. The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia. Maltepe E, etal., Biochem Biophys Res Commun. 2000 Jun 24;273(1):231-8.
17. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
18. Estrogen increases messenger RNA and immunoreactivity of aryl-hydrocarbon receptor nuclear translocator 2 in the rat mediobasal hypothalamus. Mitsushima D, etal., Biochem Biophys Res Commun 2003 Jul 25;307(2):248-53.
19. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
20. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
21. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
22. Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Reyes H, etal., Science. 1992 May 22;256(5060):1193-5. doi: 10.1126/science.256.5060.1193.
23. GOA pipeline RGD automated data pipeline
24. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
25. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
26. Daily cycle of bHLH-PAS proteins, Ah receptor and Arnt, in multiple tissues of female Sprague-Dawley rats. Richardson VM, etal., Biochem Biophys Res Commun. 1998 Nov 9;252(1):225-31. doi: 10.1006/bbrc.1998.9634.
27. The t(1;12)(q21;p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion. Salomon-Nguyen F, etal., Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6757-62.
28. Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator messenger ribonucleic acids and proteins in rat and human testis. Schultz R, etal., Endocrinology 2003 Mar;144(3):767-76.
29. Diet-relevant phytochemical intake affects the cardiac AhR and nrf2 transcriptome and reduces heart failure in hypertensive rats. Seymour EM, etal., J Nutr Biochem. 2013 Sep;24(9):1580-6. doi: 10.1016/j.jnutbio.2013.01.008. Epub 2013 Mar 22.
Additional References at PubMed
PMID:1448077   PMID:7539918   PMID:8065918   PMID:8089148   PMID:8702901   PMID:8756616   PMID:9000051   PMID:9079689   PMID:9113979   PMID:10692439   PMID:11025203   PMID:11043581  
PMID:11074397   PMID:15016652   PMID:15363889   PMID:15766748   PMID:16181639   PMID:16287860   PMID:17915197   PMID:18078967   PMID:18367654   PMID:19141293   PMID:19251700   PMID:20440072  
PMID:21059654   PMID:21445860   PMID:21602191   PMID:22792280   PMID:23275542   PMID:24001774   PMID:26245371   PMID:26827991   PMID:27750035   PMID:27782878   PMID:28396409   PMID:28602820  


Genomics

Comparative Map Data
Arnt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,686,703 - 185,745,546 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2185,680,683 - 185,745,546 (+)EnsemblGRCr8
mRatBN7.22182,997,731 - 183,056,584 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,997,736 - 183,056,580 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2190,662,514 - 190,721,330 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02188,458,053 - 188,516,629 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02183,295,003 - 183,353,822 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd2185,290,639 - 185,349,479 (+)NCBI
Lyon_Normotensive2185,517,592 - 185,576,432 (+)NCBI
Lyon_Hypertensive2185,175,158 - 185,233,978 (+)NCBI
F344_StmMcwi2185,270,136 - 185,328,950 (+)NCBI
Rnor_6.02196,594,178 - 196,651,486 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,594,303 - 196,651,179 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.02216,092,481 - 216,150,842 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42190,333,978 - 190,391,015 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2175,530,933 - 175,587,940 (+)NCBICelera
RGSC_v3.12190,296,731 - 190,353,769 (+)NCBI
Cytogenetic Map2q34NCBI
ARNT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381150,809,713 - 150,876,599 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1150,808,617 - 150,876,771 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh371150,782,189 - 150,849,075 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,048,810 - 149,115,810 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341147,595,258 - 147,662,259NCBI
Celera1123,898,224 - 123,964,878 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1122,159,809 - 122,226,754 (-)NCBIHuRef
CHM1_11152,177,524 - 152,244,584 (-)NCBICHM1_1
T2T-CHM13v2.01149,933,391 - 150,000,287 (-)NCBIT2T-CHM13v2.0
Arnt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39395,341,674 - 95,404,551 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl395,341,365 - 95,404,551 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38395,434,367 - 95,497,240 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl395,434,388 - 95,497,240 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37395,238,312 - 95,301,162 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36395,519,832 - 95,581,692 (+)NCBIMGSCv36mm8
Celera396,865,861 - 96,928,345 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.74NCBI
Arnt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955588159,462 - 233,047 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_004955588159,462 - 233,047 (-)NCBIChiLan1.0ChiLan1.0
ARNT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,956,517 - 99,022,721 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,710,135 - 98,776,351 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01126,160,017 - 126,226,222 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11129,809,434 - 129,875,629 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1129,809,431 - 129,875,629 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
ARNT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1759,941,353 - 60,010,867 (-)NCBICanFam3.1 EnsemblcanFam3CanFam3.1
CanFam3.1 Ensembl1759,941,353 - 60,010,867 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1759,385,568 - 59,456,622 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01760,956,018 - 61,028,041 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1760,956,029 - 61,028,010 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,785,290 - 59,856,876 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,869,465 - 59,941,376 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,597,849 - 60,669,366 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arnt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap111130,964,611 - 131,039,436 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_02440505822,002,839 - 22,062,779 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365801,036,973 - 1,082,984 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365801,038,420 - 1,093,319 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARNT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl498,333,459 - 98,389,457 (+)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1498,333,431 - 98,390,012 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24107,586,868 - 107,638,152 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARNT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap12012,584,962 - 12,649,795 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366603812,405,916 - 12,471,198 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arnt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477218,949,221 - 19,016,672 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_00462477218,949,108 - 19,015,504 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl194,702,667 - 4,764,331 (+)Ensembl
Arnt
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1361,773,940 - 61,830,665 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in Arnt
256 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:21
Interacting mature miRNAs:21
Transcripts:ENSRNOT00000044738, ENSRNOT00000064442
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2163997722225110681Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2169358774214358774Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2149957381221199885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2138595962205135428Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2124537199209621565Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2145807215220931416Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2122597372215234002Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085199723085Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2145807215190807215Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085199723085Rat
10043139Iddm55Insulin dependent diabetes mellitus QTL 553.10.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2150313808195313808Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085199723085Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2159440891205135267Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085199723085Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170652929215652929Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2159440891220931218Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2171994826205135428Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2143565208188565208Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2154723085199723085Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2139067258192287892Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2184856304229856304Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2184856304229856304Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2159440760195313808Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2144882354205135428Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
1357991Ael2Aortic elastin QTL 24.20.000071aorta elastin amount (VT:0003905)aortic elastin2169227906214227906Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2184856304229856304Rat
1578671Bmd10Bone mineral density QTL 105.4femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)2175931416220931416Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2182024327227024327Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2184482291229482291Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2143746578205135428Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150096616195096616Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2145306936212705578Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2147287892192287892Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660223841096Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2117415288205135428Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150096616195096616Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2182635347227635347Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837220008837Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2184856304229856304Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2165453811210453811Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2163253030208253030Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat

Markers in Region
D2Rat125  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82185,710,866 - 185,711,033 (+)Marker Load Pipeline
mRatBN7.22183,021,898 - 183,022,065 (+)MAPPERmRatBN7.2
Rnor_6.02196,618,335 - 196,618,501NCBIRnor6.0
Rnor_5.02216,116,649 - 216,116,815UniSTSRnor5.0
RGSC_v3.42190,358,165 - 190,358,332RGDRGSC3.4
RGSC_v3.42190,358,166 - 190,358,332UniSTSRGSC3.4
Celera2175,555,099 - 175,555,265UniSTS
RGSC_v3.12190,320,919 - 190,321,086RGD
SHRSP x BN Map270.0098UniSTS
SHRSP x BN Map270.0098RGD
Cytogenetic Map2q34UniSTS
D2Rat150  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82185,694,938 - 185,695,127 (+)Marker Load Pipeline
mRatBN7.22183,005,969 - 183,006,158 (+)MAPPERmRatBN7.2
Rnor_6.02196,602,418 - 196,602,606NCBIRnor6.0
Rnor_5.02216,100,756 - 216,100,944UniSTSRnor5.0
RGSC_v3.42190,342,092 - 190,342,281RGDRGSC3.4
RGSC_v3.42190,342,093 - 190,342,281UniSTSRGSC3.4
Celera2175,539,050 - 175,539,238UniSTS
RGSC_v3.12190,304,847 - 190,305,035RGD
RH 3.4 Map21215.41UniSTS
RH 3.4 Map21215.41RGD
RH 2.0 Map2896.3RGD
FHH x ACI Map278.7699RGD
Cytogenetic Map2q34UniSTS
D2Rat231  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82185,737,456 - 185,737,596 (+)Marker Load Pipeline
mRatBN7.22183,048,491 - 183,048,631 (+)MAPPERmRatBN7.2
Rnor_6.02196,644,924 - 196,645,063NCBIRnor6.0
Rnor_5.02216,143,623 - 216,143,762UniSTSRnor5.0
RGSC_v3.42190,384,759 - 190,384,899RGDRGSC3.4
RGSC_v3.42190,384,760 - 190,384,899UniSTSRGSC3.4
Celera2175,581,688 - 175,581,827UniSTS
RGSC_v3.12190,347,496 - 190,347,842RGD
SHRSP x BN Map270.0098UniSTS
SHRSP x BN Map270.0098RGD
Cytogenetic Map2q34UniSTS
D2Uia13  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82185,716,998 - 185,717,139 (+)Marker Load Pipeline
mRatBN7.22183,028,031 - 183,028,172 (+)MAPPERmRatBN7.2
Rnor_6.02196,624,467 - 196,624,607NCBIRnor6.0
Rnor_5.02216,122,781 - 216,122,921UniSTSRnor5.0
RGSC_v3.42190,364,298 - 190,364,438UniSTSRGSC3.4
Celera2175,561,231 - 175,561,371UniSTS
RGSC_v3.12190,327,051 - 190,327,192RGD
Cytogenetic Map2q34UniSTS
D2Wox41  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82185,737,978 - 185,738,694 (+)Marker Load Pipeline
mRatBN7.22183,049,013 - 183,049,729 (+)MAPPERmRatBN7.2
Rnor_6.02196,645,446 - 196,646,164NCBIRnor6.0
Rnor_5.02216,144,145 - 216,144,863UniSTSRnor5.0
RGSC_v3.42190,385,282 - 190,386,000UniSTSRGSC3.4
Celera2175,582,210 - 175,582,925UniSTS
Cytogenetic Map2q34UniSTS
AI454670  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,996,831 - 182,997,028 (+)MAPPERmRatBN7.2
Rnor_6.02196,593,283 - 196,593,479NCBIRnor6.0
Rnor_5.02216,091,621 - 216,091,817UniSTSRnor5.0
RGSC_v3.42190,332,958 - 190,333,154UniSTSRGSC3.4
Celera2175,529,913 - 175,530,109UniSTS
RH 3.4 Map21213.9UniSTS
Cytogenetic Map2q34UniSTS
Arnt  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22183,054,811 - 183,054,909 (+)MAPPERmRatBN7.2
mRatBN7.22183,054,875 - 183,054,909 (+)MAPPERmRatBN7.2
mRatBN7.22183,054,811 - 183,055,328 (+)MAPPERmRatBN7.2
Rnor_6.02196,651,246 - 196,651,794NCBIRnor6.0
Rnor_6.02196,651,246 - 196,651,343NCBIRnor6.0
Rnor_5.02216,149,945 - 216,150,493UniSTSRnor5.0
Rnor_5.02216,149,945 - 216,150,042UniSTSRnor5.0
RGSC_v3.42190,391,082 - 190,391,179UniSTSRGSC3.4
Celera2175,588,007 - 175,588,104UniSTS
Cytogenetic Map2q34UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
276 156 729 1591 4052 1011 1728 133 874 494 856 156 5394 2595 448 3965 38 1392 741 909 160 158

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001389231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY264361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY264362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY264363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY264364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY264365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U08986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U61184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000044738   ⟹   ENSRNOP00000048259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2185,700,709 - 185,745,546 (+)Ensembl
mRatBN7.2 Ensembl2183,011,332 - 183,056,580 (+)Ensembl
Rnor_6.0 Ensembl2196,594,303 - 196,651,179 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000064442   ⟹   ENSRNOP00000060764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2185,680,683 - 185,745,543 (+)Ensembl
mRatBN7.2 Ensembl2182,997,852 - 183,054,745 (+)Ensembl
Rnor_6.0 Ensembl2196,594,303 - 196,651,179 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091681   ⟹   ENSRNOP00000074418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2185,686,703 - 185,745,546 (+)Ensembl
mRatBN7.2 Ensembl2182,997,736 - 183,056,580 (+)Ensembl
Rnor_6.0 Ensembl2196,608,496 - 196,651,160 (+)Ensembl
RefSeq Acc Id: NM_001389231   ⟹   NP_001376160
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82185,686,703 - 185,745,546 (+)NCBI
mRatBN7.22182,997,731 - 183,056,584 (+)NCBI
Dahl_SR_JrHsd2185,290,639 - 185,349,479 (+)NCBI
Lyon_Normotensive2185,517,592 - 185,576,432 (+)NCBI
Lyon_Hypertensive2185,175,158 - 185,233,978 (+)NCBI
F344_StmMcwi2185,270,136 - 185,328,950 (+)NCBI
RefSeq Acc Id: NM_012780   ⟹   NP_036912
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82185,686,703 - 185,745,546 (+)NCBI
mRatBN7.22182,997,731 - 183,056,584 (+)NCBI
Dahl_SR_JrHsd2185,290,639 - 185,349,479 (+)NCBI
Lyon_Normotensive2185,517,592 - 185,576,432 (+)NCBI
Lyon_Hypertensive2185,175,158 - 185,233,978 (+)NCBI
F344_StmMcwi2185,270,136 - 185,328,950 (+)NCBI
Rnor_6.02196,594,303 - 196,651,179 (+)NCBI
Rnor_5.02216,092,481 - 216,150,842 (+)NCBI
RGSC_v3.42190,333,978 - 190,391,015 (+)RGD
Celera2175,530,933 - 175,587,940 (+)RGD
Sequence:
RefSeq Acc Id: XM_063281325   ⟹   XP_063137395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82185,686,952 - 185,745,546 (+)NCBI
RefSeq Acc Id: NP_036912   ⟸   NM_012780
- Peptide Label: isoform 1
- UniProtKB: A0A0G2K804 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048259   ⟸   ENSRNOT00000044738
Ensembl Acc Id: ENSRNOP00000074418   ⟸   ENSRNOT00000091681
Ensembl Acc Id: ENSRNOP00000060764   ⟸   ENSRNOT00000064442
RefSeq Acc Id: NP_001376160   ⟸   NM_001389231
- Peptide Label: isoform 2
- UniProtKB: Q80T28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137395   ⟸   XM_063281325
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K804 (UniProtKB/TrEMBL)
Protein Domains
bHLH   PAC   PAS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P41739-F1-model_v2 AlphaFold P41739 1-800 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691560
Promoter ID:EPDNEW_R2073
Type:multiple initiation site
Name:Arnt_1
Description:aryl hydrocarbon receptor nuclear translocator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02196,594,292 - 196,594,352EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2153 AgrOrtholog
BioCyc Gene G2FUF-52093 BioCyc
Ensembl Genes ENSRNOG00000031174 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000044738 ENTREZGENE
  ENSRNOT00000091681 ENTREZGENE
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot
  PAS domain UniProtKB/Swiss-Prot
InterPro bHLH_dom UniProtKB/Swiss-Prot
  Circadian_TF UniProtKB/Swiss-Prot
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot
  Nuc_translocat UniProtKB/Swiss-Prot
  PAC UniProtKB/Swiss-Prot
  PAS UniProtKB/Swiss-Prot
  PAS-like_dom_sf UniProtKB/Swiss-Prot
  PAS_fold UniProtKB/Swiss-Prot
KEGG Report rno:25242 UniProtKB/Swiss-Prot
NCBI Gene 25242 ENTREZGENE
PANTHER CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS UniProtKB/Swiss-Prot
Pfam HLH UniProtKB/Swiss-Prot
  PAS UniProtKB/Swiss-Prot
  PAS_11 UniProtKB/Swiss-Prot
PhenoGen Arnt PhenoGen
PRINTS NCTRNSLOCATR UniProtKB/Swiss-Prot
PROSITE BHLH UniProtKB/Swiss-Prot
  PAS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000031174 RatGTEx
SMART HLH UniProtKB/Swiss-Prot
  PAC UniProtKB/Swiss-Prot
  PAS UniProtKB/Swiss-Prot
Superfamily-SCOP Positive stranded ssRNA viruses UniProtKB/Swiss-Prot
  SSF47459 UniProtKB/Swiss-Prot
  SSF55785 UniProtKB/Swiss-Prot
UniProt A0A0G2K804 ENTREZGENE, UniProtKB/TrEMBL
  ARNT_RAT UniProtKB/Swiss-Prot
  E9PTS2_RAT UniProtKB/TrEMBL
  F1LMF9_RAT UniProtKB/TrEMBL
  P41739 ENTREZGENE
  Q80T25_RAT UniProtKB/TrEMBL
  Q80T26_RAT UniProtKB/TrEMBL
  Q80T27_RAT UniProtKB/TrEMBL
  Q80T28 ENTREZGENE, UniProtKB/TrEMBL
  Q80T29_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Arnt  aryl hydrocarbon receptor nuclear translocator  Arnt1  Aryl hydrocarbon receptor nuclear translocator 1  Symbol and Name updated 629477 APPROVED
2002-06-10 Arnt1  Aryl hydrocarbon receptor nuclear translocator 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_drugs mediates dioxin toxicity 634668
gene_expression expressed in testis 634668
gene_function may act as a transcription factor 634669
gene_process mediates dioxin toxicity 634668