Gene: Hsd3b2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2)  Rattus norvegicus

Symbol: Hsd3b2
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Description: ENCODES a protein that exhibits 3-beta-hydroxy-delta5-steroid dehydrogenase activity; dihydrotestosterone 17-beta-dehydrogenase activity; NAD binding; INVOLVED IN adrenal gland development; biphenyl metabolic process; C21-steroid hormone metabolic process; PARTICIPATES IN cortisol biosynthetic pathway; estradiol biosynthetic pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH Diabetes Mellitus, Type 2; Hyperprolactinemia; Hypertension; FOUND IN intracellular membrane-bounded organelle; mitochondrial crista; mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 1H-pyrazole (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3 beta-hydroxysteroid dehydrogenase 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3beta-hydroxysteroid dehydrogenase type 2; 3betaHSD; Hsd3b1; hydroxysteroid dehydrogenase-1, delta<5>-3-beta; LOC360348; MGC105549
Orthologs: Homo sapiens : HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2)  HGNC
Mus musculus : Hsd3b1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: not annotated on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map2q34 NCBI
RGSC Genome Assembly v3.42193,500,916 - 193,507,633-NCBI
Rat Celera Assembly2178,651,833 - 178,657,861-NCBI
Genome Assembly 3.12193,463,669 - 193,470,387-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Hsd3b2
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RGD Object Information
RGD ID: 1308676
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2013-05-28
Status: ACTIVE