Annotation (Toggle Detail/Summary View) Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (2,4,5-trichlorophenoxy)acetic acid | decreases expression | ISO | RGD:10675 | 6480464 | 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GOT1 mRNA | CTD | PMID:18579281 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:10675 | 6480464 | Ethinyl Estradiol affects the expression of GOT1 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of GOT1 mRNA | CTD | PMID:12075121 more ... | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of GOT1 mRNA | CTD | PMID:16174780 more ... | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of GOT1 mRNA | CTD | PMID:12075121 more ... | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of GOT1 mRNA | CTD | PMID:17351261 more ... | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of GOT1 mRNA | CTD | PMID:17108234 PMID:15953391 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:10675 | 6480464 | Ethinyl Estradiol results in increased expression of GOT1 mRNA | CTD | PMID:17942748 PMID:16174780 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of GOT1 mRNA | CTD | PMID:17351261 more ... | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of GOT1 mRNA | CTD | PMID:15953391 PMID:17108234 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:10675 | 6480464 | Ethinyl Estradiol results in increased expression of GOT1 mRNA | CTD | PMID:16174780 PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:10675 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GOT1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | increases expression | ISO | RGD:735827 | 6480464 | Estradiol results in increased expression of GOT1 mRNA | CTD | PMID:19167446 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:10675 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA] | CTD | PMID:21851831 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:10675 | 6480464 | Tetrachlorodibenzodioxin affects the expression of GOT1 mRNA | CTD | PMID:18343893 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:735827 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA | CTD | PMID:20106945 PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10675 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA | CTD | PMID:15328365 more ... | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:10675 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA] | CTD | PMID:21851831 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10675 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA | CTD | PMID:19770486 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10675 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA | CTD | PMID:15800033 more ... | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:10675 | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to GOT1 promoter] | CTD | PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10675 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA | CTD | PMID:19770486 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10675 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA | CTD | PMID:15800033 more ... | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:10675 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GOT1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GOT1 mRNA | CTD | PMID:16960034 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10675 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA | CTD | PMID:15800033 more ... | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:10675 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GOT1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:735827 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GOT1 mRNA | CTD | PMID:20106945 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of GOT1 mRNA | CTD | PMID:21346803 | 2-methylcholine | affects expression | ISO | RGD:735827 | 6480464 | beta-methylcholine affects the expression of GOT1 mRNA | CTD | PMID:21179406 | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1,2-dithiol-3-thione results in decreased expression of GOT1 mRNA | CTD | PMID:19162173 | aflatoxin B1 | decreases expression | ISO | RGD:10675 | 6480464 | Aflatoxin B1 results in decreased expression of GOT1 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases expression | ISO | RGD:735827 | 6480464 | Aflatoxin B1 results in increased expression of GOT1 mRNA | CTD | PMID:21641981 | aluminium trichloride | increases activity | EXP | | 6480464 | aluminum chloride results in increased activity of GOT1 protein | CTD | PMID:12197946 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of GOT1 mRNA | CTD | PMID:16483693 | baicalin | multiple interactions | EXP | | 6480464 | baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] | CTD | PMID:15645217 | benzo[a]pyrene | decreases expression | ISO | RGD:10675 | 6480464 | Benzo(a)pyrene results in decreased expression of GOT1 mRNA | CTD | PMID:19770486 PMID:21715664 | benzo[a]pyrene | increases expression | ISO | RGD:735827 | 6480464 | Benzo(a)pyrene results in increased expression of GOT1 mRNA | CTD | PMID:21632981 | benzo[a]pyrene | decreases expression | ISO | RGD:10675 | 6480464 | Benzo(a)pyrene results in decreased expression of GOT1 mRNA | CTD | PMID:21715664 PMID:19770486 | benzo[a]pyrene | decreases expression | ISO | RGD:10675 | 6480464 | Benzo(a)pyrene results in decreased expression of GOT1 mRNA | CTD | PMID:21715664 | benzo[a]pyrene | increases expression | ISO | RGD:10675 | 6480464 | Benzo(a)pyrene results in increased expression of GOT1 mRNA | CTD | PMID:20504355 | bisphenol A | increases expression | ISO | RGD:10675 | 6480464 | bisphenol A results in increased expression of GOT1 mRNA | CTD | PMID:21932408 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GOT1 mRNA | CTD | PMID:12075121 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of GOT1 mRNA | CTD | PMID:15056800 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of GOT1 protein | CTD | PMID:17098586 | capsaicin | multiple interactions | EXP | | 6480464 | Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein]; more ... | CTD | PMID:16956363 | chloroethene | decreases expression | ISO | RGD:10675 | 6480464 | Vinyl Chloride results in decreased expression of GOT1 mRNA | CTD | PMID:18579281 | chlorpyrifos | multiple interactions | ISO | RGD:10675 | 6480464 | Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in increased expression of GOT1 protein] | CTD | PMID:15991261 | ciguatoxin CTX1B | affects expression | ISO | RGD:10675 | 6480464 | Ciguatoxins affects the expression of GOT1 mRNA | CTD | PMID:18353800 | cis-caffeic acid | multiple interactions | EXP | | 6480464 | caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] | CTD | PMID:15212457 | cisplatin | increases expression | ISO | RGD:735827 | 6480464 | Cisplatin results in increased expression of GOT1 mRNA | CTD | PMID:19561079 | copper atom | affects binding | ISO | RGD:735827 | 6480464 | GOT1 protein binds to Copper | CTD | PMID:15359738 | copper(0) | affects binding | ISO | RGD:735827 | 6480464 | GOT1 protein binds to Copper | CTD | PMID:15359738 | copper(2+) sulfate | increases expression | ISO | RGD:735827 | 6480464 | Copper Sulfate results in increased expression of GOT1 mRNA | CTD | PMID:19549813 | copper(2+) sulfate | decreases expression | ISO | RGD:10675 | 6480464 | Copper Sulfate results in decreased expression of GOT1 mRNA | CTD | PMID:18579281 | coumestrol | increases expression | ISO | RGD:735827 | 6480464 | Coumestrol results in increased expression of GOT1 mRNA | CTD | PMID:19167446 | coumestrol | multiple interactions | ISO | RGD:735827 | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GOT1 mRNA | CTD | PMID:19167446 | curcumin | multiple interactions | EXP | | 6480464 | Curcumin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein]; more ... | CTD | PMID:16956363 | cyclosporin A | increases expression | ISO | RGD:735827 | 6480464 | Cyclosporine results in increased expression of GOT1 mRNA | CTD | PMID:20106945 | cyclosporin A | increases expression | ISO | RGD:735827 | 6480464 | Cyclosporine results in increased expression of GOT1 mRNA | CTD | PMID:20106945 PMID:21632981 | cyclosporin A | multiple interactions | EXP | | 6480464 | Cyclosporine inhibits the reaction [Thioacetamide results in increased expression of GOT1 protein] | CTD | PMID:15770714 | cypermethrin | multiple interactions | ISO | RGD:10675 | 6480464 | [cypermethrin co-treated with Chlorpyrifos] results in increased expression of GOT1 protein; more ... | CTD | PMID:15991261 | cypermethrin | increases activity | EXP | | 6480464 | cypermethrin results in increased activity of GOT1 protein | CTD | PMID:2466999 PMID:15365239 | cypermethrin | increases secretion | EXP | | 6480464 | cypermethrin results in increased secretion of GOT1 protein | CTD | PMID:11428908 | cypermethrin | multiple interactions | EXP | | 6480464 | Proadifen promotes the reaction [cypermethrin results in increased secretion of GOT1 protein]; more ... | CTD | PMID:11428908 | cypermethrin | increases activity | EXP | | 6480464 | cypermethrin results in increased activity of GOT1 protein | CTD | PMID:15365239 PMID:2466999 | cypermethrin | decreases activity | EXP | | 6480464 | cypermethrin results in decreased activity of GOT1 protein | CTD | PMID:2466999 | Delta(9)-tetrahydrocannabinol | increases expression | EXP | | 6480464 | Tetrahydrocannabinol results in increased expression of GOT1 mRNA | CTD | PMID:17578508 | diarsenic trioxide | decreases expression | ISO | RGD:735827 | 6480464 | arsenic trioxide results in decreased expression of GOT1 protein | CTD | PMID:19364129 | diarsenic trioxide | increases expression | ISO | RGD:735827 | 6480464 | arsenic trioxide results in increased expression of GOT1 mRNA | CTD | PMID:20458559 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of GOT1 mRNA | CTD | PMID:21266533 | diethyl phthalate | increases activity | EXP | | 6480464 | diethyl phthalate results in increased activity of GOT1 protein | CTD | PMID:16750591 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of GOT1 mRNA | CTD | PMID:21551480 | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of GOT1 protein | CTD | PMID:8612723 | endosulfan | decreases activity | EXP | | 6480464 | Endosulfan results in decreased activity of GOT1 protein | CTD | PMID:6180524 PMID:3388749 | endosulfan | decreases activity | EXP | | 6480464 | Endosulfan results in decreased activity of GOT1 protein | CTD | PMID:3388749 PMID:6180524 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of GOT1 mRNA | CTD | PMID:16098508 | ethanol | multiple interactions | EXP | | 6480464 | pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of GOT1 protein] | CTD | PMID:15318101 | fenvalerate | increases activity | EXP | | 6480464 | fenvalerate results in increased activity of GOT1 protein | CTD | PMID:15186033 | gamma-hexachlorocyclohexane | increases expression | EXP | | 6480464 | Lindane results in increased expression of GOT1 mRNA | CTD | PMID:17785943 | genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of GOT1 mRNA | CTD | PMID:12075121 | hyaluronic acid | decreases expression | EXP | | 6480464 | Hyaluronic Acid analog results in decreased expression of GOT1 protein | CTD | PMID:23178681 | hydrogen peroxide | decreases expression | EXP | | 6480464 | Hydrogen Peroxide results in decreased expression of GOT1 protein | CTD | PMID:23178681 | iron atom | multiple interactions | EXP | | 6480464 | Capsaicin inhibits the reaction [Iron results in increased activity of GOT1 protein]; more ... | CTD | PMID:16956363 | iron atom | increases activity | EXP | | 6480464 | Iron results in increased activity of GOT1 protein | CTD | PMID:16956363 | iron(3+) sulfate | multiple interactions | EXP | | 6480464 | Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein]; more ... | CTD | PMID:16956363 | iron(3+) sulfate | increases activity | EXP | | 6480464 | ferric sulfate results in increased activity of GOT1 protein | CTD | PMID:16956363 | N-methyl-4-phenylpyridinium | increases expression | ISO | RGD:10675 | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of GOT1 mRNA | CTD | PMID:22776087 | N-nitrosodiethylamine | increases activity | EXP | | 6480464 | Diethylnitrosamine results in increased activity of GOT1 protein | CTD | PMID:17034775 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | Plant Extracts inhibits the reaction [Diethylnitrosamine results in increased activity of GOT1 protein] | CTD | PMID:17034775 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:10675 | 6480464 | [Diethylnitrosamine co-treated with HRAS protein] results in increased activity of GOT1 protein | CTD | PMID:12499697 | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of GOT1 mRNA | CTD | PMID:17072980 | paracetamol | affects expression | ISO | RGD:10675 | 6480464 | Acetaminophen affects the expression of GOT1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | RGD:735827 | 6480464 | Acetaminophen results in increased expression of GOT1 mRNA | CTD | PMID:22230336 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of GOT1 mRNA | CTD | PMID:17366322 | paraquat | decreases activity | EXP | | 6480464 | Paraquat results in decreased activity of GOT1 protein | CTD | PMID:17481832 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of GOT1 mRNA | CTD | PMID:16555045 | phenobarbital | multiple interactions | ISO | RGD:10675 | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of GOT1 mRNA] | CTD | PMID:19482888 | phenobarbital | affects expression | ISO | RGD:10675 | 6480464 | Phenobarbital affects the expression of GOT1 mRNA | CTD | PMID:23091169 | phenobarbital | multiple interactions | EXP | | 6480464 | Phenobarbital inhibits the reaction [cypermethrin results in increased secretion of GOT1 protein] | CTD | PMID:11428908 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of GOT1 mRNA | CTD | PMID:19162173 | phenobarbital | decreases expression | ISO | RGD:10675 | 6480464 | Phenobarbital results in decreased expression of GOT1 mRNA | CTD | PMID:19482888 | pioglitazone | multiple interactions | EXP | | 6480464 | pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of GOT1 protein] | CTD | PMID:15318101 | pirinixic acid | increases expression | ISO | RGD:10675 | 6480464 | pirinixic acid results in increased expression of GOT1 mRNA | CTD | PMID:18445702 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of GOT1 mRNA | CTD | PMID:19162173 | progesterone | increases expression | ISO | RGD:735827 | 6480464 | Progesterone results in increased expression of GOT1 mRNA | CTD | PMID:18037150 | propiconazole | decreases expression | ISO | RGD:10675 | 6480464 | propiconazole results in decreased expression of GOT1 mRNA | CTD | PMID:19363144 PMID:21278054 | propiconazole | decreases expression | ISO | RGD:10675 | 6480464 | propiconazole results in decreased expression of GOT1 mRNA | CTD | PMID:21278054 PMID:19363144 | quercetin | increases expression | ISO | RGD:10675 | 6480464 | Quercetin results in increased expression of GOT1 mRNA | CTD | PMID:16455785 | ranitidine | multiple interactions | EXP | | 6480464 | [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GOT1 mRNA | CTD | PMID:16415329 | sevoflurane | affects expression | EXP | | 6480464 | sevoflurane affects the expression of GOT1 mRNA | CTD | PMID:15967596 | tamoxifen | affects expression | ISO | RGD:10675 | 6480464 | Tamoxifen affects the expression of GOT1 mRNA | CTD | PMID:20937368 PMID:17555576 | tamoxifen | affects expression | ISO | RGD:10675 | 6480464 | Tamoxifen affects the expression of GOT1 mRNA | CTD | PMID:17555576 PMID:20937368 | tert-butyl hydroperoxide | multiple interactions | EXP | | 6480464 | caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein]; more ... | CTD | PMID:15212457 | tert-butyl hydroperoxide | increases activity | EXP | | 6480464 | tert-Butylhydroperoxide results in increased activity of GOT1 protein | CTD | PMID:15645217 PMID:15212457 | tert-butyl hydroperoxide | increases expression | EXP | | 6480464 | tert-Butylhydroperoxide results in increased expression of GOT1 protein | CTD | PMID:15095147 | tert-butyl hydroperoxide | increases activity | EXP | | 6480464 | tert-Butylhydroperoxide results in increased activity of GOT1 protein | CTD | PMID:15212457 PMID:15645217 | tert-butyl hydroperoxide | multiple interactions | EXP | | 6480464 | Plant Extracts inhibits the reaction [tert-Butylhydroperoxide results in increased expression of GOT1 protein] | CTD | PMID:15095147 | tert-butyl hydroperoxide | multiple interactions | EXP | | 6480464 | baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] | CTD | PMID:15645217 | testosterone | decreases expression | ISO | RGD:10675 | 6480464 | Testosterone results in decreased expression of GOT1 mRNA | CTD | PMID:21669218 | testosterone | increases expression | EXP | | 6480464 | Testosterone results in increased expression of GOT1 protein | CTD | PMID:3432395 | tetrachloromethane | increases activity | EXP | | 6480464 | Carbon Tetrachloride results in increased activity of GOT1 protein | CTD | PMID:17200984 | tetrachloromethane | multiple interactions | EXP | | 6480464 | Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of GOT1 protein] | CTD | PMID:15095147 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of GOT1 mRNA | CTD | PMID:16239168 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of GOT1 protein | CTD | PMID:15095147 | thioacetamide | multiple interactions | EXP | | 6480464 | Cyclosporine inhibits the reaction [Thioacetamide results in increased expression of GOT1 protein] | CTD | PMID:15770714 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of GOT1 protein | CTD | PMID:15770714 | trimellitic anhydride | increases expression | ISO | RGD:10675 | 6480464 | trimellitic anhydride results in increased expression of GOT1 mRNA | CTD | PMID:19042947 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of GOT1 protein | CTD | PMID:21315101 | zinc atom | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of GOT1 mRNA | CTD | PMID:12672911 | zinc(0) | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of GOT1 mRNA | CTD | PMID:12672911 | |
Gene Ontology AnnotationsBiological Process











