Gene: Ncf2 (neutrophil cytosolic factor 2) Rattus norvegicus
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Symbol: Ncf2
Name: neutrophil cytosolic factor 2
Description: ENCODES a protein that exhibits protein C-terminus binding (ortholog); Rac GTPase binding (ortholog); superoxide-generating NADPH oxidase activity (ortholog); INVOLVED IN aging; cellular response to hormone stimulus; positive regulation of blood pressure; PARTICIPATES IN Leishmania infection pathway; phagocytosis pathway; ASSOCIATED WITH Burns; Diabetes Mellitus, Experimental; Hypertension; FOUND IN cytoplasm; membrane; acrosomal vesicle (ortholog); INTERACTS WITH 17beta-estradiol; aflatoxin B1; AICA ribonucleotide
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC364018; NCF-2; neutrophil cytosol factor 2; neutrophil NADPH oxidase factor 2
Orthologs:
Homo sapiens (human) : NCF2 (neutrophil cytosolic factor 2)  HGNC
Mus musculus (house mouse) : Ncf2 (neutrophil cytosolic factor 2)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Ncf2 (neutrophil cytosolic factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NCF2 (neutrophil cytosolic factor 2)
Canis lupus familiaris (dog) : NCF2 (neutrophil cytosolic factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncf2 (neutrophil cytosolic factor 2)
more info ...
Allele / Splice: Ncf2em1Mcwi   Ncf2em4Mcwi  
Genetic Models: SS-Tg(Slc12a1-Ncf2-2A-Luc)-Ncf2em1Mcwi SS-Ncf2em1Mcwi SS-Ncf2em4Mcwi
Is Marker For: Strains:   SS.BN-(D13Rat151-D13Rat197)-Tg(Slc12a1-Ncf2-2A-Luc)26Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01370,226,441 - 70,259,019 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01375,197,561 - 75,229,600 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41367,806,516 - 67,834,105 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11367,797,870 - 67,848,218 (+)NCBI
Celera1364,862,007 - 64,890,467 (+)NCBI
Cytogenetic Map13q21NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ncf2
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 1309424
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-08-01
Status: ACTIVE