Bcl11b (BCL11 transcription factor B) - Rat Genome Database

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Gene: Bcl11b (BCL11 transcription factor B) Rattus norvegicus
Analyze
Symbol: Bcl11b
Name: BCL11 transcription factor B
RGD ID: 1311128
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in hematopoietic stem cell migration; lymphoid lineage cell migration into thymus; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including T cell differentiation; epithelial cell development; and neuron differentiation. Predicted to be located in neuron projection. Predicted to be part of SWI/SNF complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 49. Orthologous to human BCL11B (BCL11 transcription factor B); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B-cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B (zinc finger protein); B-cell leukemia/lymphoma 11B; B-cell lymphoma/leukemia 11B; BAF chromatin remodeling complex subunit BCL11B; BCL11B, BAF complex component; COUP-TF-interacting protein 2 long form; Ctip2; LOC314423
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86132,598,968 - 132,692,123 (-)NCBIGRCr8
mRatBN7.26126,834,531 - 126,927,720 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6126,834,531 - 126,928,224 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6126,958,692 - 127,050,867 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06127,253,714 - 127,345,900 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06126,612,161 - 126,704,296 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06131,834,097 - 131,927,251 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6131,834,097 - 131,926,272 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,004,477 - 141,097,643 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46132,292,671 - 132,384,572 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16132,296,789 - 132,389,378 (-)NCBI
Celera6124,393,881 - 124,486,186 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12565905   PMID:12717433   PMID:15664173   PMID:16670294   PMID:16809611   PMID:17998389   PMID:18199763   PMID:18215621   PMID:18255031   PMID:18595722   PMID:19092943  
PMID:19251658   PMID:21752992   PMID:22082260   PMID:23144223   PMID:24705758   PMID:25100583   PMID:26096706   PMID:27577752   PMID:27959403   PMID:27959755  


Genomics

Comparative Map Data
Bcl11b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86132,598,968 - 132,692,123 (-)NCBIGRCr8
mRatBN7.26126,834,531 - 126,927,720 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6126,834,531 - 126,928,224 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6126,958,692 - 127,050,867 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06127,253,714 - 127,345,900 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06126,612,161 - 126,704,296 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06131,834,097 - 131,927,251 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6131,834,097 - 131,926,272 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,004,477 - 141,097,643 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46132,292,671 - 132,384,572 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16132,296,789 - 132,389,378 (-)NCBI
Celera6124,393,881 - 124,486,186 (-)NCBICelera
Cytogenetic Map6q32NCBI
BCL11B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381499,169,287 - 99,272,197 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1499,169,287 - 99,272,197 (-)EnsemblGRCh38hg38GRCh38
GRCh371499,635,624 - 99,738,534 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361498,705,377 - 98,807,575 (-)NCBINCBI36Build 36hg18NCBI36
Build 341498,705,376 - 98,807,575NCBI
Celera1479,691,368 - 79,793,512 (-)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1479,819,226 - 79,921,464 (-)NCBIHuRef
CHM1_11499,573,389 - 99,675,578 (-)NCBICHM1_1
T2T-CHM13v2.01493,400,844 - 93,503,767 (-)NCBIT2T-CHM13v2.0
Bcl11b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912107,876,662 - 107,970,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12107,876,662 - 107,969,861 (-)EnsemblGRCm39 Ensembl
GRCm3812107,910,403 - 108,004,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12107,910,403 - 108,003,602 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712109,148,613 - 109,241,624 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612108,363,030 - 108,451,028 (-)NCBIMGSCv36mm8
Celera12109,151,974 - 109,245,238 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.1NCBI
Bcl11b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543820,564,449 - 20,637,103 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543820,562,345 - 20,637,662 (-)NCBIChiLan1.0ChiLan1.0
BCL11B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215100,325,797 - 100,429,008 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11499,542,293 - 99,645,444 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01479,795,262 - 79,898,472 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11499,122,231 - 99,205,962 (-)NCBIpanpan1.1PanPan1.1panPan2
BCL11B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1867,622,592 - 67,713,922 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl867,622,708 - 67,714,404 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha867,145,953 - 67,237,226 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0867,909,299 - 68,000,574 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl867,909,387 - 68,001,543 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1867,570,743 - 67,661,895 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0867,636,646 - 67,728,187 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0868,033,837 - 68,125,174 (-)NCBIUU_Cfam_GSD_1.0
Bcl11b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086406,972,307 - 7,063,288 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366043,023,844 - 3,110,083 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366043,023,781 - 3,110,104 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL11B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7120,205,008 - 120,295,936 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17120,205,008 - 120,295,737 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27127,759,537 - 127,855,267 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BCL11B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12477,122,591 - 77,222,562 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2477,122,689 - 77,221,454 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605364,224,342 - 64,347,710 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcl11b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247344,560,699 - 4,647,858 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247344,560,362 - 4,649,219 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bcl11b
262 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:392
Count of miRNA genes:218
Interacting mature miRNAs:256
Transcripts:ENSRNOT00000007602
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat

Markers in Region
Bcl11b  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,837,358 - 126,837,583 (+)MAPPERmRatBN7.2
Rnor_6.06131,836,925 - 131,837,149NCBIRnor6.0
Rnor_5.06141,007,305 - 141,007,529UniSTSRnor5.0
RGSC_v3.46132,294,397 - 132,294,621UniSTSRGSC3.4
Celera6124,396,709 - 124,396,933UniSTS
Cytogenetic Map6q32UniSTS
stSG632080  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,835,779 - 126,837,168 (+)MAPPERmRatBN7.2
Rnor_6.06131,835,346 - 131,836,734NCBIRnor6.0
Rnor_5.06141,005,726 - 141,007,114UniSTSRnor5.0
RGSC_v3.46132,292,818 - 132,294,206UniSTSRGSC3.4
Celera6124,395,130 - 124,396,518UniSTS
Cytogenetic Map6q32UniSTS
stSG632129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,888,831 - 126,889,797 (+)MAPPERmRatBN7.2
Rnor_6.06131,888,435 - 131,889,400NCBIRnor6.0
Rnor_5.06141,058,815 - 141,059,780UniSTSRnor5.0
RGSC_v3.46132,345,869 - 132,346,834UniSTSRGSC3.4
Celera6124,448,318 - 124,449,283UniSTS
Cytogenetic Map6q32UniSTS
ECD17061  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,838,523 - 126,838,935 (+)MAPPERmRatBN7.2
Rnor_6.06131,838,090 - 131,838,501NCBIRnor6.0
Rnor_5.06141,008,470 - 141,008,881UniSTSRnor5.0
RGSC_v3.46132,295,562 - 132,295,973UniSTSRGSC3.4
Celera6124,397,874 - 124,398,285UniSTS
Cytogenetic Map6q32UniSTS
REN47704  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,836,818 - 126,837,102 (+)MAPPERmRatBN7.2
Rnor_6.06131,836,385 - 131,836,668NCBIRnor6.0
Rnor_5.06141,006,765 - 141,007,048UniSTSRnor5.0
RGSC_v3.46132,293,857 - 132,294,140UniSTSRGSC3.4
Celera6124,396,169 - 124,396,452UniSTS
Cytogenetic Map6q32UniSTS
REN47709  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,838,402 - 126,838,659 (+)MAPPERmRatBN7.2
Rnor_6.06131,837,969 - 131,838,225NCBIRnor6.0
Rnor_5.06141,008,349 - 141,008,605UniSTSRnor5.0
RGSC_v3.46132,295,441 - 132,295,697UniSTSRGSC3.4
Celera6124,397,753 - 124,398,009UniSTS
Cytogenetic Map6q32UniSTS
REN47699  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,835,712 - 126,835,946 (+)MAPPERmRatBN7.2
Rnor_6.06131,835,279 - 131,835,512NCBIRnor6.0
Rnor_5.06141,005,659 - 141,005,892UniSTSRnor5.0
RGSC_v3.46132,292,751 - 132,292,984UniSTSRGSC3.4
Celera6124,395,063 - 124,395,296UniSTS
Cytogenetic Map6q32UniSTS
REN47882  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,875,656 - 126,875,897 (+)MAPPERmRatBN7.2
Rnor_6.06131,875,262 - 131,875,502NCBIRnor6.0
Rnor_5.06141,045,642 - 141,045,882UniSTSRnor5.0
RGSC_v3.46132,332,696 - 132,332,936UniSTSRGSC3.4
Celera6124,435,125 - 124,435,365UniSTS
Cytogenetic Map6q32UniSTS
REN47927  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,883,083 - 126,883,373 (+)MAPPERmRatBN7.2
Rnor_6.06131,882,687 - 131,882,976NCBIRnor6.0
Rnor_5.06141,053,067 - 141,053,356UniSTSRnor5.0
RGSC_v3.46132,340,121 - 132,340,410UniSTSRGSC3.4
Celera6124,442,550 - 124,442,839UniSTS
Cytogenetic Map6q32UniSTS
REN47976  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,893,425 - 126,893,712 (+)MAPPERmRatBN7.2
Rnor_6.06131,893,029 - 131,893,315NCBIRnor6.0
Rnor_5.06141,063,409 - 141,063,695UniSTSRnor5.0
RGSC_v3.46132,350,463 - 132,350,749UniSTSRGSC3.4
Celera6124,452,989 - 124,453,275UniSTS
Cytogenetic Map6q32UniSTS
Bcl11b  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26126,837,375 - 126,837,775 (+)MAPPERmRatBN7.2
Rnor_6.06131,836,942 - 131,837,341NCBIRnor6.0
Rnor_5.06141,007,322 - 141,007,721UniSTSRnor5.0
Celera6124,396,726 - 124,397,125UniSTS
Cytogenetic Map6q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 8 11 60
Low 2 42 14 6 8 6 8 32 39 11
Below cutoff 1 18 18 18 8 8 6 3 2 8

Sequence


RefSeq Acc Id: ENSRNOT00000007602   ⟹   ENSRNOP00000007602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6126,837,307 - 126,914,229 (-)Ensembl
Rnor_6.0 Ensembl6131,836,674 - 131,914,028 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084057   ⟹   ENSRNOP00000068641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6126,834,531 - 126,914,229 (-)Ensembl
Rnor_6.0 Ensembl6131,834,097 - 131,926,272 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000088421   ⟹   ENSRNOP00000069404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6126,834,531 - 126,913,655 (-)Ensembl
Rnor_6.0 Ensembl6131,834,097 - 131,926,272 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098362   ⟹   ENSRNOP00000091986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6126,834,531 - 126,928,224 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099802   ⟹   ENSRNOP00000084654
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6126,835,192 - 126,928,224 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111465   ⟹   ENSRNOP00000078832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6126,834,531 - 126,928,224 (-)Ensembl
RefSeq Acc Id: NM_001277287   ⟹   NP_001264216
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,598,968 - 132,691,102 (-)NCBI
mRatBN7.26126,834,531 - 126,926,674 (-)NCBI
Rnor_6.06131,834,097 - 131,926,272 (-)NCBI
Rnor_5.06141,004,477 - 141,097,643 (-)NCBI
Celera6124,393,881 - 124,486,186 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001277288   ⟹   NP_001264217
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,598,968 - 132,691,102 (-)NCBI
mRatBN7.26126,834,531 - 126,926,674 (-)NCBI
Rnor_6.06131,834,097 - 131,926,272 (-)NCBI
Rnor_5.06141,004,477 - 141,097,643 (-)NCBI
Celera6124,393,881 - 124,486,186 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240540   ⟹   XP_006240602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,598,973 - 132,692,120 (-)NCBI
mRatBN7.26126,834,536 - 126,927,714 (-)NCBI
Rnor_6.06131,836,621 - 131,927,251 (-)NCBI
Rnor_5.06141,004,477 - 141,097,643 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112399   ⟹   XP_038968327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,598,973 - 132,692,122 (-)NCBI
mRatBN7.26126,834,536 - 126,927,719 (-)NCBI
RefSeq Acc Id: XM_039112400   ⟹   XP_038968328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,598,973 - 132,692,123 (-)NCBI
mRatBN7.26126,834,536 - 126,927,720 (-)NCBI
RefSeq Acc Id: XM_063262010   ⟹   XP_063118080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,598,973 - 132,692,123 (-)NCBI
RefSeq Acc Id: NP_001264217   ⟸   NM_001277288
- Peptide Label: isoform 2
- UniProtKB: H9N1L3 (UniProtKB/TrEMBL),   A0A0G2JVA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264216   ⟸   NM_001277287
- Peptide Label: isoform 1
- UniProtKB: H9N1L4 (UniProtKB/TrEMBL),   A6KBF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240602   ⟸   XM_006240540
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JVA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000007602   ⟸   ENSRNOT00000007602
RefSeq Acc Id: ENSRNOP00000068641   ⟸   ENSRNOT00000084057
RefSeq Acc Id: ENSRNOP00000069404   ⟸   ENSRNOT00000088421
RefSeq Acc Id: XP_038968328   ⟸   XM_039112400
- Peptide Label: isoform X2
- UniProtKB: A6KBF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968327   ⟸   XM_039112399
- Peptide Label: isoform X1
- UniProtKB: A6KBF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000091986   ⟸   ENSRNOT00000098362
RefSeq Acc Id: ENSRNOP00000078832   ⟸   ENSRNOT00000111465
RefSeq Acc Id: ENSRNOP00000084654   ⟸   ENSRNOT00000099802
RefSeq Acc Id: XP_063118080   ⟸   XM_063262010
- Peptide Label: isoform X3
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A0W4-F1-model_v2 AlphaFold D4A0W4 1-921 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694816
Promoter ID:EPDNEW_R5341
Type:single initiation site
Name:Bcl11b_1
Description:B-cell CLL/lymphoma 11B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06131,926,366 - 131,926,426EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311128 AgrOrtholog
BioCyc Gene G2FUF-36317 BioCyc
Ensembl Genes ENSRNOG00000005776 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007602.6 UniProtKB/TrEMBL
  ENSRNOT00000084057.2 UniProtKB/TrEMBL
  ENSRNOT00000088421.2 UniProtKB/TrEMBL
  ENSRNOT00000098362 ENTREZGENE
  ENSRNOT00000098362.1 UniProtKB/TrEMBL
  ENSRNOT00000099802.1 UniProtKB/TrEMBL
  ENSRNOT00000111465 ENTREZGENE
  ENSRNOT00000111465.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:314423 UniProtKB/TrEMBL
NCBI Gene 314423 ENTREZGENE
PANTHER B-CELL LYMPHOMA/LEUKEMIA 11 UniProtKB/TrEMBL
  B-CELL LYMPHOMA/LEUKEMIA 11B UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Bcl11b PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005776 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A0G2JTB3_RAT UniProtKB/TrEMBL
  A0A0G2JVA1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GC26_RAT UniProtKB/TrEMBL
  A6KBF0 ENTREZGENE, UniProtKB/TrEMBL
  D4A0W4_RAT UniProtKB/TrEMBL
  H9N1L3 ENTREZGENE, UniProtKB/TrEMBL
  H9N1L4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-11-28 Bcl11b  BCL11 transcription factor B  Bcl11b  BAF chromatin remodeling complex subunit BCL11B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2019-04-02 Bcl11b  BAF chromatin remodeling complex subunit BCL11B  Bcl11b  BCL11B, BAF complex component  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2018-11-09 Bcl11b  BCL11B, BAF complex component  Bcl11b  B-cell CLL/lymphoma 11B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-13 Bcl11b  B-cell CLL/lymphoma 11B  Bcl11b  B-cell CLL/lymphoma 11B (zinc finger protein)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Bcl11b  B-cell CLL/lymphoma 11B (zinc finger protein)  Bcl11b  B-cell leukemia/lymphoma 11B   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Bcl11b  B-cell leukemia/lymphoma 11B   Bcl11b_predicted  B-cell leukemia/lymphoma 11B (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Bcl11b_predicted  B-cell leukemia/lymphoma 11B (predicted)      Symbol and Name status set to approved 70820 APPROVED