Gene: Tardbp (TAR DNA binding protein) Rattus norvegicus
Symbol: Tardbp
Name: TAR DNA binding protein
Description: ENCODES a protein that exhibits RNA binding; double-stranded DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN positive regulation of insulin secretion; response to endoplasmic reticulum stress; 3'-UTR-mediated mRNA stabilization (ortholog); ASSOCIATED WITH Alzheimer Disease (ortholog); Amyotrophic Lateral Sclerosis (ortholog); Amyotrophic Lateral Sclerosis 10 (ortholog); FOUND IN cytoplasm; interchromatin granule; nuclear speck; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bis(2-ethylhexyl) phthalate
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC298648; TAR DNA-binding protein 43; Tdp-43
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.05165,432,089 - 165,442,112-NCBI
Rat Cytogenetic Map5q36 NCBI
RGSC Genome Assembly v5.05169,088,684 - 169,099,216-NCBI
RGSC Genome Assembly v3.45165,698,665 - 165,709,531-NCBI
Rat Celera Assembly5157,327,910 - 157,337,955-NCBI
Genome Assembly 3.15165,708,851 - 165,719,708-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Tardbp
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1310906
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2015-08-18
Status: ACTIVE