Gene: Ikbkb (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) Rattus norvegicus
Analyze
Symbol: Ikbkb
Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Description: ENCODES a protein that exhibits ATP binding; protein heterodimerization activity; IkappaB kinase activity (ortholog); INVOLVED IN neuron projection development; positive regulation of cell proliferation; positive regulation of neuron death; PARTICIPATES IN adenosine signaling pathway; FasL mediated signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH Alzheimer Disease; Arthritis, Experimental; Colitis; FOUND IN cytosol; IkappaB kinase complex; intracellular membrane-bounded organelle; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 2-amino-2-deoxy-D-galactopyranose
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AIM-1; I-kappa-B kinase 2; I-kappa-B-kinase beta; IKK-B; IKK-beta; IKK2; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01674,177,233 - 74,230,809 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01673,809,854 - 73,863,636 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41673,804,730 - 73,858,510 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11673,805,346 - 73,858,348 (+)NCBI
Celera1667,214,025 - 67,266,348 (+)NCBI
Cytogenetic Map16q12.5NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ikbkb
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 621375
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-20
Status: ACTIVE