App (amyloid beta (A4) precursor protein)

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Keyword

Gene: App (amyloid beta (A4) precursor protein) Rattus norvegicus

Symbol:

App

Name:

amyloid beta (A4) precursor protein

Description:

ENCODES a protein that exhibits growth factor receptor binding; peptidase activator activity; acetylcholine receptor binding (ortholog); INVOLVED IN induction of apoptosis; positive regulation of peptidase activity; adult locomotory behavior (ortholog); PARTICIPATES IN glypican signaling pathway; Alzheimer disease pathway; ASSOCIATED WITH Alzheimer Disease (ortholog); Cerebral Amyloid Angiopathy (ortholog); Cerebral Amyloid Angiopathy, App-Related (ortholog); FOUND IN Golgi apparatus; neuron projection; apical part of cell (ortholog); INTERACTS WITH (+)-catechin; (S)-naringenin; (S)-nicotine

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

ABPP; AG; alzheimer disease amyloid A4 protein homolog; amyloid A4; amyloid beta A4 protein; amyloidogenic glycoprotein

Orthologs:

Homo sapiens : APP (amyloid beta (A4) precursor protein) HGNC
Mus musculus : App (amyloid beta (A4) precursor protein) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	11	q11		NCBI
RGSC Genome Assembly v5.0	11	28,049,786 - 28,265,107	-	NCBI
RGSC Genome Assembly v3.4	11	24,457,855 - 24,693,851	-	NCBI
Rat Celera Assembly	11	23,853,696 - 24,069,048	-	NCBI
Genome Assembly 3.1	11	24,457,854 - 24,693,851	-	NCBI
RH 3.4	11	94.7		RGD