Gene: Lrp5 (low density lipoprotein receptor-related protein 5) Rattus norvegicus
Symbol: Lrp5
Name: low density lipoprotein receptor-related protein 5
Description: ENCODES a protein that exhibits Wnt-activated receptor activity (ortholog); Wnt-protein binding (ortholog); INVOLVED IN response to peptide hormone; adipose tissue development (ortholog); anatomical structure regression (ortholog); PARTICIPATES IN altered Wnt signaling, canonical pathway; N-cadherin signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Exudative Vitreoretinopathy 4 (ortholog); Leber Congenital Amaurosis (ortholog); Osteochondrodysplasias (ortholog); FOUND IN mitochondrion (ortholog); plasma membrane (ortholog); receptor complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
Also known as: LOC293649; low-density lipoprotein receptor-related protein 5; MGC188568
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01218,816,833 - 218,920,150-NCBI
Rat Cytogenetic Map1q42 NCBI
RGSC Genome Assembly v5.01225,689,353 - 225,793,075-NCBI
RGSC Genome Assembly v3.41206,102,750 - 206,206,350-NCBI
Rat Celera Assembly1198,369,819 - 198,473,093-NCBI
Genome Assembly 3.11206,256,235 - 206,359,808-NCBI

Launch Genome Browser (GBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Lrp5
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1309329
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE