Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Htatsf1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HTATSF1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of HTATSF1 mRNA | CTD | PMID:17557909 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Htatsf1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of HTATSF1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of HTATSF1 mRNA | CTD | PMID:21632981 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of HTATSF1 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of HTATSF1 mRNA | CTD | PMID:21346803 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | HTATSF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of HTATSF1 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Htatsf1 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of HTATSF1 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of HTATSF1 protein | CTD | PMID:34186270 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of HTATSF1 mRNA | CTD | PMID:30047161 | all-trans-retinoic acid | increases expression | ISO | Htatsf1 (Mus musculus) | 6480464 | Tretinoin results in increased expression of HTATSF1 mRNA | CTD | PMID:16604517 | all-trans-retinoic acid | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of HTATSF1 mRNA | CTD | PMID:21934132 and PMID:33167477 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of HTATSF1 mRNA | CTD | PMID:30047161 | Aroclor 1254 | decreases expression | ISO | Htatsf1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of HTATSF1 mRNA | CTD | PMID:23650126 | arsane | affects methylation | ISO | HTATSF1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of HTATSF1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | HTATSF1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of HTATSF1 gene | CTD | PMID:25304211 | arsenous acid | increases response to substance | ISO | HTATSF1 (Homo sapiens) | 6480464 | HTATSF1 protein results in increased susceptibility to Arsenic Trioxide | CTD | PMID:20707922 | azoxystrobin | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | azoxystrobin results in decreased expression of HTATSF1 mRNA | CTD | PMID:33512557 | benzo[a]pyrene | multiple interactions | ISO | Htatsf1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of HTATSF1 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | affects methylation | ISO | HTATSF1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of HTATSF1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | HTATSF1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of HTATSF1 5' UTR and Benzo(a)pyrene results in increased methylation of HTATSF1 exon | CTD | PMID:27901495 | benzo[b]fluoranthene | decreases expression | ISO | Htatsf1 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of HTATSF1 mRNA | CTD | PMID:26377693 | benzo[b]fluoranthene | multiple interactions | ISO | Htatsf1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of HTATSF1 mRNA | CTD | PMID:27858113 | bisphenol A | multiple interactions | ISO | HTATSF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of HTATSF1 mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of HTATSF1 protein | CTD | PMID:34186270 | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of HTATSF1 mRNA | CTD | PMID:24136188 | caffeine | affects phosphorylation | ISO | HTATSF1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of HTATSF1 protein | CTD | PMID:35688186 | chrysene | multiple interactions | ISO | Htatsf1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of HTATSF1 mRNA | CTD | PMID:27858113 | cocaine | multiple interactions | EXP | | 6480464 | [(3R)-((2 more ... | CTD | PMID:32312805 | coumarin | affects phosphorylation | ISO | HTATSF1 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of HTATSF1 protein | CTD | PMID:35688186 | decabromodiphenyl ether | increases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of HTATSF1 protein | CTD | PMID:31675489 | dexamethasone | multiple interactions | ISO | HTATSF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of HTATSF1 mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases response to substance | ISO | HTATSF1 (Homo sapiens) | 6480464 | HTATSF1 protein results in increased susceptibility to Arsenic Trioxide | CTD | PMID:20707922 | dibenzo[a,l]pyrene | increases expression | ISO | Htatsf1 (Mus musculus) | 6480464 | dibenzo(a and l)pyrene results in increased expression of HTATSF1 mRNA | CTD | PMID:25908611 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of HTATSF1 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | HTATSF1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HTATSF1 mRNA | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of HTATSF1 mRNA | CTD | PMID:29803840 | fenpyroximate | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | fenpyroximate results in decreased expression of HTATSF1 mRNA | CTD | PMID:33512557 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of HTATSF1 mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | ISO | Htatsf1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HTATSF1 mRNA | CTD | PMID:22206623 | folic acid | decreases expression | ISO | Htatsf1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of HTATSF1 mRNA | CTD | PMID:25629700 | FR900359 | affects phosphorylation | ISO | HTATSF1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of HTATSF1 protein | CTD | PMID:37730182 | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of HTATSF1 gene | CTD | PMID:35440735 | gold atom | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Gold results in decreased expression of HTATSF1 mRNA | CTD | PMID:25523186 | gold(0) | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Gold results in decreased expression of HTATSF1 mRNA | CTD | PMID:25523186 | hydrogen peroxide | affects expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of HTATSF1 mRNA | CTD | PMID:20044591 | hydrogen peroxide | multiple interactions | ISO | Htatsf1 (Mus musculus) | 6480464 | [Hydrogen Peroxide co-treated with N-(oxo-5 more ... | CTD | PMID:31494107 | hydroquinone O-beta-D-glucopyranoside | increases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Arbutin results in increased expression of HTATSF1 mRNA | CTD | PMID:17103032 | indometacin | multiple interactions | ISO | HTATSF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of HTATSF1 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of HTATSF1 protein | CTD | PMID:32959892 | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of HTATSF1 mRNA | CTD | PMID:24136188 | methylmercury chloride | increases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of HTATSF1 mRNA | CTD | PMID:23179753 and PMID:26272509 | parathion | increases expression | ISO | Htatsf1 (Mus musculus) | 6480464 | Parathion results in increased expression of HTATSF1 mRNA | CTD | PMID:34813904 | picoxystrobin | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | picoxystrobin results in decreased expression of HTATSF1 mRNA | CTD | PMID:33512557 | resveratrol | multiple interactions | ISO | HTATSF1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of HTATSF1 mRNA | CTD | PMID:23557933 | rotenone | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of HTATSF1 mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | ISO | HTATSF1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of HTATSF1 mRNA | CTD | PMID:30047161 | testosterone enanthate | affects expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of HTATSF1 mRNA | CTD | PMID:17440010 | tetraphene | decreases expression | ISO | Htatsf1 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of HTATSF1 mRNA | CTD | PMID:26377693 | tetraphene | multiple interactions | ISO | Htatsf1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of HTATSF1 mRNA | CTD | PMID:27858113 | thimerosal | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of HTATSF1 mRNA | CTD | PMID:27188386 | titanium dioxide | increases expression | ISO | Htatsf1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of HTATSF1 mRNA | CTD | PMID:29264374 | torcetrapib | increases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of HTATSF1 mRNA | CTD | PMID:23228038 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of HTATSF1 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of HTATSF1 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | HTATSF1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HTATSF1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of HTATSF1 mRNA | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of HTATSF1 mRNA | CTD | PMID:23179753 and PMID:27188386 | valproic acid | decreases methylation | ISO | HTATSF1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of HTATSF1 gene | CTD | PMID:29154799 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of HTATSF1 mRNA | CTD | PMID:23555832 | vorinostat | decreases expression | ISO | HTATSF1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of HTATSF1 mRNA | CTD | PMID:27188386 | WIN 55212-2 | multiple interactions | EXP | | 6480464 | [(3R)-((2 more ... | CTD | PMID:32312805 | |