Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MBNL3 mRNA] | CTD | PMID:31150632 | 1,3-dinitrobenzene | increases expression | EXP | | 6480464 | 3-dinitrobenzene results in increased expression of MBNL3 mRNA | CTD | PMID:21983209 | 17beta-estradiol | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of MBNL3 mRNA | CTD | PMID:21185374 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Mbnl3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Mbnl3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MBNL3 mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 4,4'-sulfonyldiphenol | increases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | bisphenol S results in increased expression of MBNL3 mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | increases methylation | ISO | Mbnl3 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of MBNL3 promoter | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | increases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | Fenretinide results in increased expression of MBNL3 mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | affects expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Decitabine affects the expression of MBNL3 mRNA | CTD | PMID:23300844 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of MBNL3 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of MBNL3 mRNA | CTD | PMID:27153756 | aflatoxin B1 | decreases methylation | ISO | MBNL3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of MBNL3 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of MBNL3 mRNA | CTD | PMID:23724009 and PMID:33167477 | aristolochic acid A | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of MBNL3 mRNA | CTD | PMID:33212167 | belinostat | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | belinostat results in increased expression of MBNL3 mRNA | CTD | PMID:26272509 | belinostat | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA | CTD | PMID:27188386 | benzo[a]pyrene | increases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of MBNL3 mRNA | CTD | PMID:20713471 and PMID:23735875 | benzo[a]pyrene | affects methylation | ISO | MBNL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MBNL3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | MBNL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MBNL3 5' UTR and Benzo(a)pyrene results in increased methylation of MBNL3 exon | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of MBNL3 mRNA | CTD | PMID:20106945 more ... | bisphenol A | increases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of MBNL3 mRNA | CTD | PMID:26063408 | bisphenol A | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MBNL3 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of MBNL3 mRNA | CTD | PMID:34585602 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MBNL3 mRNA | CTD | PMID:34947998 | bisphenol A | affects expression | ISO | MBNL3 (Homo sapiens) | 6480464 | bisphenol A affects the expression of MBNL3 mRNA | CTD | PMID:30903817 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of MBNL3 gene | CTD | PMID:28505145 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MBNL3 mRNA | CTD | PMID:25181051 more ... | CGP 52608 | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MBNL3 gene] | CTD | PMID:28238834 | chlordecone | increases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | Chlordecone results in increased expression of MBNL3 mRNA | CTD | PMID:33711761 | choline | multiple interactions | ISO | Mbnl3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MBNL3 gene | CTD | PMID:20938992 | chromium(6+) | affects expression | ISO | Mbnl3 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of MBNL3 mRNA | CTD | PMID:24374135 | cisplatin | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of MBNL3 mRNA | CTD | PMID:27594783 | cisplatin | affects expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Cisplatin affects the expression of MBNL3 mRNA | CTD | PMID:23300844 | copper atom | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of MBNL3 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of MBNL3 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of MBNL3 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of MBNL3 mRNA | CTD | PMID:19770486 | cyclosporin A | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of MBNL3 mRNA | CTD | PMID:20106945 more ... | dibutyl phthalate | decreases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of MBNL3 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MBNL3 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of MBNL3 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | entinostat results in increased expression of MBNL3 mRNA | CTD | PMID:26272509 and PMID:27188386 | entinostat | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA | CTD | PMID:27188386 | epoxiconazole | decreases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of MBNL3 mRNA | CTD | PMID:35436446 | ethanol | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Ethanol results in increased expression of MBNL3 mRNA | CTD | PMID:23378141 | ethanol | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [Ethanol co-treated with Folic Acid] results in increased expression of MBNL3 mRNA | CTD | PMID:23378141 | folic acid | multiple interactions | ISO | Mbnl3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MBNL3 gene | CTD | PMID:20938992 | folic acid | decreases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of MBNL3 mRNA | CTD | PMID:25629700 | folic acid | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [Ethanol co-treated with Folic Acid] results in increased expression of MBNL3 mRNA | CTD | PMID:23378141 | fulvestrant | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MBNL3 gene | CTD | PMID:31601247 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of MBNL3 mRNA | CTD | PMID:33387578 | hydroquinone | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | hydroquinone results in decreased expression of MBNL3 mRNA | CTD | PMID:31256213 | L-methionine | multiple interactions | ISO | Mbnl3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MBNL3 gene | CTD | PMID:20938992 | lead(0) | affects expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Lead affects the expression of MBNL3 mRNA | CTD | PMID:28903495 | mercury dibromide | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of MBNL3 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA | CTD | PMID:27188386 | methylmercury chloride | affects expression | EXP | | 6480464 | methylmercuric chloride affects the expression of MBNL3 mRNA | CTD | PMID:20864626 | methylmercury chloride | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of MBNL3 mRNA | CTD | PMID:28001369 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of MBNL3 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | Mbnl3 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of MBNL3 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of MBNL3 mRNA | CTD | PMID:27106289 and PMID:34911549 | panobinostat | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | panobinostat results in increased expression of MBNL3 mRNA | CTD | PMID:26272509 | paracetamol | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MBNL3 mRNA | CTD | PMID:22230336 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of MBNL3 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of MBNL3 mRNA | CTD | PMID:29067470 | PCB138 | multiple interactions | ISO | Mbnl3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | phenformin | increases expression | EXP | | 6480464 | Phenformin results in increased expression of MBNL3 mRNA | CTD | PMID:31324951 | phenylmercury acetate | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of MBNL3 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA | CTD | PMID:27188386 | quercetin | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of MBNL3 mRNA | CTD | PMID:21632981 | SB 431542 | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of MBNL3 mRNA | CTD | PMID:23806026 | sodium arsenite | decreases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of MBNL3 mRNA | CTD | PMID:37682722 | succimer | multiple interactions | ISO | Mbnl3 (Mus musculus) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of MBNL3 mRNA | CTD | PMID:26378955 | sunitinib | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of MBNL3 mRNA | CTD | PMID:31533062 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of MBNL3 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MBNL3 mRNA] | CTD | PMID:31150632 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of MBNL3 mRNA | CTD | PMID:25729387 | trichostatin A | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of MBNL3 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA | CTD | PMID:27188386 | trimellitic anhydride | increases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of MBNL3 mRNA | CTD | PMID:19042947 | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of MBNL3 mRNA | CTD | PMID:30589522 | urethane | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of MBNL3 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MBNL3 mRNA | CTD | PMID:25979313 | valproic acid | decreases methylation | ISO | MBNL3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of MBNL3 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | Mbnl3 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of MBNL3 mRNA | CTD | PMID:24896083 | valproic acid | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MBNL3 mRNA | CTD | PMID:23179753 more ... | vincristine | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of MBNL3 mRNA | CTD | PMID:23649840 | vorinostat | multiple interactions | ISO | MBNL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of MBNL3 mRNA | CTD | PMID:18769122 | vorinostat | increases expression | ISO | MBNL3 (Homo sapiens) | 6480464 | vorinostat results in increased expression of MBNL3 mRNA | CTD | PMID:26272509 | |