(+)-Tetrandrine multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [arsenite co-treated with tetrandrine] results in decreased expression of ERBB2 protein CTD PMID:31934280 (+)-Tetrandrine decreases expression ISO ERBB2 (Homo sapiens) 6480464 tetrandrine results in decreased expression of ERBB2 protein CTD PMID:31934280 (-)-epigallocatechin 3-gallate decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 epigallocatechin gallate results in decreased phosphorylation of ERBB2 protein CTD PMID:18618485 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases activity ISO ERBB2 (Homo sapiens) 6480464 o and p'-DDT results in increased activity of ERBB2 protein CTD PMID:11222871 and PMID:9443065 1,2-dimethylhydrazine increases expression ISO Erbb2 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of ERBB2 mRNA CTD PMID:22206623 17beta-estradiol multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Cycloheximide co-treated with Estradiol] results in decreased expression of ERBB2 mRNA more ... CTD PMID:15072547 more ... 17beta-estradiol increases expression ISO Erbb2 (Mus musculus) 6480464 Estradiol results in increased expression of ERBB2 mRNA CTD PMID:17640349 17beta-estradiol multiple interactions ISO Erbb2 (Mus musculus) 6480464 [ERBB2 protein co-treated with ERBB3 protein] results in increased susceptibility to Estradiol CTD PMID:19861407 17beta-estradiol increases expression ISO ERBB2 (Homo sapiens) 6480464 Estradiol results in increased expression of ERBB2 mRNA CTD PMID:17555868 17beta-estradiol decreases expression ISO ERBB2 (Homo sapiens) 6480464 Estradiol results in decreased expression of ERBB2 mRNA and Estradiol results in decreased expression of ERBB2 protein CTD PMID:15072547 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO ERBB2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of ERBB2 mRNA CTD PMID:11162886 and PMID:17555868 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO ERBB2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ERBB2 mRNA CTD PMID:26238291 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO ERBB2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of ERBB2 mRNA CTD PMID:22298810 and PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ERBB2 mRNA CTD PMID:21215274 and PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Erbb2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ERBB2 promoter] CTD PMID:19654925 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of ERBB2 protein CTD PMID:11350689 2-deoxy-D-glucose multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Deoxyglucose co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein and Deoxyglucose inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 2-hydroxypropanoic acid decreases expression ISO ERBB2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ERBB2 mRNA CTD PMID:30851411 3,3',5,5'-tetrabromobisphenol A increases expression EXP 6480464 tetrabromobisphenol A results in increased expression of ERBB2 mRNA CTD PMID:26353976 3,3'-diindolylmethane multiple interactions ISO ERBB2 (Homo sapiens) 6480464 3 more ... CTD PMID:16580691 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol decreases expression ISO ERBB2 (Homo sapiens) 6480464 fluorotelomer alcohols results in decreased expression of ERBB2 mRNA CTD PMID:16393665 3,7-dihydropurine-6-thione decreases expression EXP 6480464 Mercaptopurine results in decreased expression of ERBB2 mRNA CTD PMID:23358152 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ERBB2 mRNA CTD PMID:28628672 3-Nitrobenzanthrone decreases expression ISO ERBB2 (Homo sapiens) 6480464 3-nitrobenzanthrone results in decreased expression of ERBB2 mRNA CTD PMID:34036453 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1 and 2-dithiol-3-thione results in increased expression of ERBB2 mRNA CTD PMID:19162173 4'-epidoxorubicin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to [Epirubicin co-treated with CMF regimen] and ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:16446318 more ... 4-hydroxynon-2-enal decreases expression ISO ERBB2 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in decreased expression of ERBB2 mRNA CTD PMID:12419474 4-nonylphenol decreases expression ISO ERBB2 (Homo sapiens) 6480464 4-nonylphenol results in decreased expression of ERBB2 mRNA CTD PMID:16393665 5-fluorouracil multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil] more ... CTD PMID:15737843 more ... 5-fluorouracil affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 mRNA alternative form affects the susceptibility to Fluorouracil CTD PMID:36639866 5-fluorouracil affects expression ISO ERBB2 (Homo sapiens) 6480464 Fluorouracil affects the expression of ERBB2 mRNA CTD PMID:15205334 5-fluorouracil decreases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 mRNA results in decreased susceptibility to Fluorouracil and ERBB2 results in decreased susceptibility to Fluorouracil CTD PMID:18337622 and PMID:21712253 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ERBB2 mRNA CTD PMID:24780913 and PMID:30047161 acetaldehyde affects expression ISO Erbb2 (Mus musculus) 6480464 Acetaldehyde affects the expression of ERBB2 mRNA CTD PMID:22634333 acetylsalicylic acid decreases expression ISO ERBB2 (Homo sapiens) 6480464 Aspirin results in decreased expression of ERBB2 mRNA and Aspirin results in decreased expression of ERBB2 protein CTD PMID:19424877 acetylsalicylic acid increases expression ISO ERBB2 (Homo sapiens) 6480464 Aspirin results in increased expression of ERBB2 mRNA CTD PMID:20457246 acrolein multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ERBB2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ERBB2 mRNA CTD PMID:32699268 acrylamide decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 Acrylamide analog results in decreased phosphorylation of ERBB2 protein CTD PMID:10753475 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of ERBB2 mRNA CTD PMID:28959563 afimoxifene increases expression ISO Erbb2 (Mus musculus) 6480464 afimoxifene results in increased expression of ERBB2 mRNA CTD PMID:17640349 afimoxifene decreases expression ISO ERBB2 (Homo sapiens) 6480464 afimoxifene results in decreased expression of ERBB2 mRNA CTD PMID:15072547 afimoxifene decreases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 results in decreased susceptibility to afimoxifene CTD PMID:21233418 afimoxifene multiple interactions ISO ERBB2 (Homo sapiens) 6480464 afimoxifene inhibits the reaction [beta-hexachlorocyclohexane promotes the reaction [ERBB2 protein binds to ERBB3 protein]] and afimoxifene inhibits the reaction [Estrogens results in decreased expression of ERBB2 mRNA] CTD PMID:12439862 and PMID:21233418 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of ERBB2 mRNA CTD PMID:33354967 aldehydo-D-glucose multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Glucose deficiency co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein and Glucose deficiency inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 all-trans-retinoic acid decreases expression ISO ERBB2 (Homo sapiens) 6480464 Tretinoin results in decreased expression of ERBB2 mRNA and Tretinoin results in decreased expression of ERBB2 protein CTD PMID:16752155 and PMID:21934132 all-trans-retinoic acid increases phosphorylation ISO Erbb2 (Mus musculus) 6480464 Tretinoin results in increased phosphorylation of ERBB2 protein CTD PMID:16357442 all-trans-retinoic acid multiple interactions ISO Erbb2 (Mus musculus) 6480464 HBEGF protein promotes the reaction [Tretinoin results in increased phosphorylation of ERBB2 protein] CTD PMID:16357442 alpha-pinene multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ERBB2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ERBB2 mRNA CTD PMID:32699268 amiloride decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 Amiloride results in decreased phosphorylation of ERBB2 protein CTD PMID:16059913 amitrole increases expression EXP 6480464 Amitrole results in increased expression of ERBB2 mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ERBB2 mRNA CTD PMID:16483693 androgen antagonist multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB2 mRNA CTD PMID:25607892 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO ERBB2 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CXCL8 mRNA]] and pyrazolanthrone inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of CXCL8 protein]] CTD PMID:33396024 apigenin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Apigenin co-treated with Fluorouracil] results in decreased expression of ERBB2 protein CTD PMID:19885610 arsane multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of ERBB2 mRNA more ... CTD PMID:32525701 and PMID:33396024 arsenic atom multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of ERBB2 mRNA more ... CTD PMID:32525701 and PMID:33396024 arsenite(3-) multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [arsenite co-treated with tetrandrine] results in decreased expression of ERBB2 protein more ... CTD PMID:31646340 more ... arsenite(3-) decreases expression ISO ERBB2 (Homo sapiens) 6480464 arsenite results in decreased expression of ERBB2 mRNA and arsenite results in decreased expression of ERBB2 protein CTD PMID:31646340 and PMID:31934280 arsenite(3-) affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 affects the susceptibility to arsenite CTD PMID:31773452 baicalein multiple interactions ISO ERBB2 (Homo sapiens) 6480464 baicalein results in decreased expression of and results in decreased phosphorylation of ERBB2 protein CTD PMID:36988316 baicalein decreases expression ISO ERBB2 (Homo sapiens) 6480464 baicalein results in decreased expression of ERBB2 mRNA CTD PMID:36988316 benzo[a]pyrene multiple interactions ISO Erbb2 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to ERBB2 promoter] CTD PMID:19654925 benzo[a]pyrene affects methylation ISO ERBB2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ERBB2 5' UTR CTD PMID:27901495 benzo[a]pyrene increases methylation ISO ERBB2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ERBB2 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO ERBB2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of ERBB2 mRNA CTD PMID:16269432 more ... benzo[a]pyrene increases expression ISO ERBB2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of ERBB2 protein CTD PMID:32717239 Benzo[k]fluoranthene decreases expression ISO ERBB2 (Homo sapiens) 6480464 benzo(k)fluoranthene results in decreased expression of ERBB2 mRNA CTD PMID:21635667 benzophenanthridine decreases expression ISO ERBB2 (Homo sapiens) 6480464 Benzophenanthridines analog results in decreased expression of ERBB2 mRNA CTD PMID:23117580 berberine multiple interactions ISO ERBB2 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Berberine results in decreased expression of ERBB2 protein] and Berberine results in decreased expression of and results in increased ubiquitination of ERBB2 protein CTD PMID:33325633 beta-hexachlorocyclohexane increases expression ISO Erbb2 (Mus musculus) 6480464 beta-hexachlorocyclohexane results in increased expression of ERBB2 mRNA CTD PMID:17640349 beta-hexachlorocyclohexane multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [beta-hexachlorocyclohexane promotes the reaction [ERBB2 protein binds to ERBB3 protein]] more ... CTD PMID:12439862 beta-hexachlorocyclohexane increases activity ISO ERBB2 (Homo sapiens) 6480464 beta-hexachlorocyclohexane results in increased activity of ERBB2 protein CTD PMID:11222871 and PMID:9443065 beta-hexachlorocyclohexane increases expression ISO ERBB2 (Homo sapiens) 6480464 beta-hexachlorocyclohexane results in increased expression of ERBB2 protein CTD PMID:12948864 beta-naphthoflavone decreases expression ISO ERBB2 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased expression of ERBB2 mRNA CTD PMID:32858204 bifenthrin affects binding ISO ERBB2 (Homo sapiens) 6480464 bifenthrin binds to ERBB2 protein CTD PMID:32278787 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of ERBB2 mRNA CTD PMID:29945229 bisdemethoxycurcumin increases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in increased susceptibility to bisdemethoxycurcumin CTD PMID:34291863 bisdemethoxycurcumin decreases expression ISO ERBB2 (Homo sapiens) 6480464 bisdemethoxycurcumin results in decreased expression of ERBB2 protein CTD PMID:34291863 bisphenol A increases phosphorylation ISO Erbb2 (Mus musculus) 6480464 bisphenol A results in increased phosphorylation of ERBB2 protein CTD PMID:21988766 and PMID:32353937 bisphenol A increases expression ISO Erbb2 (Mus musculus) 6480464 bisphenol A results in increased expression of ERBB2 mRNA CTD PMID:32156529 and PMID:32353937 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ERBB2 mRNA CTD PMID:34947998 bisphenol A increases expression ISO ERBB2 (Homo sapiens) 6480464 bisphenol A results in increased expression of ERBB2 mRNA CTD PMID:29275510 bisphenol A affects expression ISO ERBB2 (Homo sapiens) 6480464 bisphenol A affects the expression of ERBB2 mRNA CTD PMID:30903817 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ERBB2 mRNA CTD PMID:25181051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB2 mRNA CTD PMID:25607892 bisphenol A decreases expression ISO Erbb2 (Mus musculus) 6480464 bisphenol A results in decreased expression of ERBB2 mRNA CTD PMID:26063408 bisphenol F multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [bisphenol F co-treated with Fulvestrant] results in decreased methylation of ERBB2 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ERBB2 mRNA CTD PMID:28628672 and PMID:31601247 bortezomib multiple interactions ISO ERBB2 (Homo sapiens) 6480464 Bortezomib promotes the reaction [lapatinib results in decreased phosphorylation of ERBB2 protein] and lapatinib promotes the reaction [Bortezomib results in decreased phosphorylation of ERBB2 protein] CTD PMID:20701607 bortezomib decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 Bortezomib results in decreased phosphorylation of ERBB2 protein CTD PMID:20701607 bosutinib decreases phosphorylation EXP 6480464 bosutinib results in decreased phosphorylation of ERBB2 protein CTD PMID:18385429 butanal decreases expression ISO ERBB2 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of ERBB2 mRNA CTD PMID:26079696 Butylparaben multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB2 mRNA CTD PMID:25607892 cadmium atom multiple interactions ISO ERBB2 (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [Cadmium results in decreased expression of ERBB2 mRNA] CTD PMID:31646340 cadmium atom decreases expression ISO ERBB2 (Homo sapiens) 6480464 Cadmium results in decreased expression of ERBB2 mRNA CTD PMID:31646340 caffeine affects phosphorylation ISO ERBB2 (Homo sapiens) 6480464 Caffeine affects the phosphorylation of ERBB2 protein CTD PMID:35688186 canertinib multiple interactions ISO ERBB2 (Homo sapiens) 6480464 Canertinib inhibits the reaction [EGF protein results in increased phosphorylation of ERBB2 protein] CTD PMID:18927496 cannabidiol multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of ERBB2 mRNA more ... CTD PMID:32992648 cannabidiol decreases expression ISO ERBB2 (Homo sapiens) 6480464 Cannabidiol results in decreased expression of ERBB2 mRNA CTD PMID:32992648 capsaicin decreases expression ISO ERBB2 (Homo sapiens) 6480464 Capsaicin results in decreased expression of ERBB2 protein CTD PMID:19855437 capsaicin affects expression ISO ERBB2 (Homo sapiens) 6480464 Capsaicin affects the expression of ERBB2 mRNA CTD PMID:19502594 captan decreases expression ISO Erbb2 (Mus musculus) 6480464 Captan results in decreased expression of ERBB2 mRNA CTD PMID:31558096 carbamazepine decreases expression ISO ERBB2 (Homo sapiens) 6480464 Carbamazepine results in decreased expression of ERBB2 mRNA and Carbamazepine results in decreased expression of ERBB2 protein CTD PMID:16965676 and PMID:17147113 carbamazepine affects expression ISO Erbb2 (Mus musculus) 6480464 Carbamazepine affects the expression of ERBB2 mRNA CTD PMID:22634333 carbamazepine multiple interactions ISO ERBB2 (Homo sapiens) 6480464 Carbamazepine results in increased degradation of and results in decreased expression of ERBB2 protein CTD PMID:17147113 carboplatin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Thiotepa co-treated with Carboplatin] CTD PMID:16446318 CGP 52608 multiple interactions ISO ERBB2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to ERBB2 gene] CTD PMID:28238834 chloroquine decreases expression ISO ERBB2 (Homo sapiens) 6480464 Chloroquine results in decreased expression of ERBB2 protein CTD PMID:20332299 chloroquine multiple interactions ISO ERBB2 (Homo sapiens) 6480464 Chloroquine inhibits the reaction [tephrosin results in increased degradation of ERBB2 protein] CTD PMID:20056314 chlorothalonil increases activity ISO ERBB2 (Homo sapiens) 6480464 tetrachloroisophthalonitrile results in increased activity of ERBB2 protein CTD PMID:11222871 choline multiple interactions ISO Erbb2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ERBB2 mRNA CTD PMID:20938992 chromium(6+) affects expression ISO ERBB2 (Homo sapiens) 6480464 chromium hexavalent ion affects the expression of ERBB2 mRNA CTD PMID:18053681 cisplatin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Cisplatin] more ... CTD PMID:15737843 more ... cisplatin decreases expression ISO ERBB2 (Homo sapiens) 6480464 Cisplatin results in decreased expression of ERBB2 mRNA CTD PMID:27392435 cisplatin affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to Cisplatin CTD PMID:10327070 cisplatin decreases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 mRNA results in decreased susceptibility to Cisplatin and ERBB2 results in decreased susceptibility to Cisplatin CTD PMID:18337622 and PMID:21712253 clozapine affects phosphorylation EXP 6480464 Clozapine affects the phosphorylation of ERBB2 protein CTD PMID:26961615 cobalt dichloride decreases expression ISO ERBB2 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of ERBB2 mRNA CTD PMID:19376846 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of ERBB2 mRNA CTD PMID:26033743 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of ERBB2 mRNA CTD PMID:26033743 copper(II) sulfate decreases expression ISO ERBB2 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of ERBB2 mRNA CTD PMID:19549813 cordycepin decreases expression ISO ERBB2 (Homo sapiens) 6480464 cordycepin results in decreased expression of ERBB2 protein CTD PMID:33948356 coumarin decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 coumarin results in decreased phosphorylation of ERBB2 protein CTD PMID:35688186 coumestrol multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in decreased expression of ERBB2 mRNA CTD PMID:19167446 crocidolite asbestos decreases expression ISO ERBB2 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased expression of ERBB2 protein CTD PMID:15626777 Cruentaren A decreases expression ISO ERBB2 (Homo sapiens) 6480464 cruentaren A results in decreased expression of ERBB2 protein CTD PMID:24450340 CU-O LINKAGE decreases expression ISO ERBB2 (Homo sapiens) 6480464 cupric oxide results in decreased expression of ERBB2 mRNA CTD PMID:22077320 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of ERBB2 mRNA CTD PMID:26577399 Cuprizon affects expression EXP 6480464 Cuprizone affects the expression of ERBB2 mRNA CTD PMID:27523638 curcumin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of AK1 protein more ... CTD PMID:17918158 and PMID:25866362 curcumin increases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in increased susceptibility to Curcumin and ERBB2 protein results in increased susceptibility to Curcumin analog CTD PMID:25866362 and PMID:34291863 curcumin increases degradation ISO ERBB2 (Homo sapiens) 6480464 Curcumin analog results in increased degradation of ERBB2 protein CTD PMID:25866362 curcumin decreases expression ISO ERBB2 (Homo sapiens) 6480464 Curcumin analog results in decreased expression of ERBB2 mRNA more ... CTD PMID:17041101 more ... cycloheximide multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Cycloheximide co-treated with Estradiol] results in decreased expression of ERBB2 mRNA more ... CTD PMID:15072547 more ... cycloheximide increases degradation ISO ERBB2 (Homo sapiens) 6480464 Cycloheximide results in increased degradation of ERBB2 protein CTD PMID:25866362 cycloheximide decreases expression ISO ERBB2 (Homo sapiens) 6480464 Cycloheximide results in decreased expression of ERBB2 mRNA and Cycloheximide results in decreased expression of ERBB2 protein CTD PMID:15072547 more ... cyclophosphamide multiple interactions ISO ERBB2 (Homo sapiens) 6480464 ERBB2 affects the susceptibility to [Doxorubicin co-treated with Cyclophosphamide co-treated with docetaxel] more ... CTD PMID:15834928 more ... cyclosporin A decreases expression ISO ERBB2 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ERBB2 mRNA CTD PMID:20106945 more ... cyhalothrin affects binding ISO ERBB2 (Homo sapiens) 6480464 cyhalothrin binds to ERBB2 protein CTD PMID:32278787 D-glucose multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Glucose deficiency co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein and Glucose deficiency inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 DDE multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 DDT increases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 DDT results in increased phosphorylation of ERBB2 protein CTD PMID:9070211 delphinidin decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 delphinidin results in decreased phosphorylation of ERBB2 protein CTD PMID:18618485 demethoxycurcumin increases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in increased susceptibility to demethoxycurcumin CTD PMID:34291863 demethoxycurcumin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [demethoxycurcumin results in increased degradation of ERBB2 protein] and demethoxycurcumin results in decreased expression of and results in increased degradation of ERBB2 protein CTD PMID:34291863 dexamethasone multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ERBB2 mRNA CTD PMID:28628672 dextran sulfate multiple interactions ISO Erbb2 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ERBB2 mRNA CTD PMID:29950665 dibenz[a,h]anthracene decreases expression ISO ERBB2 (Homo sapiens) 6480464 1 more ... CTD PMID:16269432 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of ERBB2 mRNA CTD PMID:17379624 dibutyl phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 dimethylarsinic acid multiple interactions EXP 6480464 Cacodylic Acid results in increased expression of and results in increased phosphorylation of ERBB2 protein CTD PMID:32890875 dioxygen multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of ERBB2 mRNA more ... CTD PMID:32992648 dorsomorphin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ERBB2 mRNA CTD PMID:27188386 doxorubicin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Doxorubicin] more ... CTD PMID:15486187 more ... doxorubicin increases expression ISO ERBB2 (Homo sapiens) 6480464 Doxorubicin results in increased expression of ERBB2 mRNA CTD PMID:29803840 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of ERBB2 protein CTD PMID:17308081 doxorubicin multiple interactions EXP 6480464 Doxorubicin promotes the reaction [HSP90AA1 protein binds to ERBB2 protein] more ... CTD PMID:17308081 and PMID:19801490 doxorubicin multiple interactions ISO Erbb2 (Mus musculus) 6480464 NRG1 protein affects the reaction [Doxorubicin affects the phosphorylation of ERBB2 protein] CTD PMID:15833803 doxorubicin decreases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in decreased susceptibility to Doxorubicin and ERBB2 results in decreased susceptibility to Doxorubicin CTD PMID:21712253 more ... doxorubicin affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to Doxorubicin CTD PMID:10327070 doxorubicin affects expression ISO ERBB2 (Homo sapiens) 6480464 Doxorubicin affects the expression of ERBB2 mRNA CTD PMID:15205334 dutasteride increases expression ISO ERBB2 (Homo sapiens) 6480464 Dutasteride results in increased expression of ERBB2 mRNA CTD PMID:17636412 elemental selenium increases expression ISO ERBB2 (Homo sapiens) 6480464 Selenium results in increased expression of ERBB2 mRNA CTD PMID:19244175 elemental selenium multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in increased expression of ERBB2 mRNA CTD PMID:19244175 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of ERBB2 mRNA CTD PMID:29391264 endosulfan decreases expression ISO ERBB2 (Homo sapiens) 6480464 Endosulfan results in decreased expression of ERBB2 mRNA CTD PMID:30090376 enzacamene multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB2 mRNA CTD PMID:25607892 epoxiconazole multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 ethanol increases expression ISO Erbb2 (Mus musculus) 6480464 Ethanol results in increased expression of ERBB2 mRNA CTD PMID:35149083 ethyl trans-caffeate affects expression ISO ERBB2 (Homo sapiens) 6480464 ethyl caffeate affects the expression of ERBB2 protein CTD PMID:24892518 ethyl trans-caffeate multiple interactions ISO ERBB2 (Homo sapiens) 6480464 ethyl caffeate affects the phosphorylation of and affects the activity of ERBB2 protein CTD PMID:24892518 etoposide multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide] more ... CTD PMID:21712253 and PMID:25866362 etoposide decreases expression ISO ERBB2 (Homo sapiens) 6480464 Etoposide results in decreased expression of ERBB2 mRNA CTD PMID:15228094 etoposide decreases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in decreased susceptibility to Etoposide and ERBB2 results in decreased susceptibility to Etoposide CTD PMID:21712253 and PMID:25866362 etoposide affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to Etoposide CTD PMID:10327070 fipronil increases expression EXP 6480464 fipronil results in increased expression of ERBB2 mRNA CTD PMID:34044035 fisetin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 fisetin results in decreased phosphorylation of and results in increased degradation of ERBB2 protein CTD PMID:30431692 fludioxonil affects binding ISO ERBB2 (Homo sapiens) 6480464 fludioxonil binds to ERBB2 protein CTD PMID:32278787 fluvalinate affects binding ISO ERBB2 (Homo sapiens) 6480464 fluvalinate binds to ERBB2 protein CTD PMID:32278787 folic acid multiple interactions ISO Erbb2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ERBB2 mRNA CTD PMID:20938992 folpet decreases expression ISO Erbb2 (Mus musculus) 6480464 folpet results in decreased expression of ERBB2 mRNA CTD PMID:31558096 formaldehyde increases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 Formaldehyde results in increased phosphorylation of ERBB2 protein CTD PMID:36534342 fulvestrant increases expression ISO ERBB2 (Homo sapiens) 6480464 Fulvestrant results in increased expression of ERBB2 mRNA CTD PMID:15072547 and PMID:31646340 fulvestrant multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [bisphenol F co-treated with Fulvestrant] results in decreased methylation of ERBB2 gene more ... CTD PMID:31601247 and PMID:31646340 fulvestrant affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 affects the susceptibility to fulvestrant CTD PMID:24169358 furan increases expression EXP 6480464 furan results in increased expression of ERBB2 mRNA CTD PMID:27387713 gefitinib multiple interactions ISO ERBB2 (Homo sapiens) 6480464 gefitinib inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of ERBB2 protein] and gefitinib results in decreased activity of [EGFR protein binds to ERBB2 protein] CTD PMID:17898861 gefitinib decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 gefitinib results in decreased phosphorylation of ERBB2 protein CTD PMID:16243822 geldanamycin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [geldanamycin binds to HSP90B1 protein] inhibits the reaction [HSP90B1 protein binds to ERBB2 protein] more ... CTD PMID:18655187 and PMID:8617772 geldanamycin decreases expression ISO ERBB2 (Homo sapiens) 6480464 geldanamycin results in decreased expression of ERBB2 protein CTD PMID:24450340 geldanamycin increases degradation ISO ERBB2 (Homo sapiens) 6480464 geldanamycin results in increased degradation of ERBB2 protein CTD PMID:11071886 more ... genistein multiple interactions ISO ERBB2 (Homo sapiens) 6480464 Genistein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which affects the phosphorylation of ERBB2 protein] more ... CTD PMID:33396024 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of ERBB2 mRNA CTD PMID:33387578 glucose multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Glucose deficiency co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein and Glucose deficiency inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 haloperidol multiple interactions EXP 6480464 Haloperidol results in increased expression of and results in increased phosphorylation of ERBB2 protein CTD PMID:26961615 Heptachlor epoxide increases activity ISO ERBB2 (Homo sapiens) 6480464 Heptachlor Epoxide results in increased activity of ERBB2 protein CTD PMID:11222871 hydrogen peroxide affects expression ISO ERBB2 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of ERBB2 mRNA CTD PMID:20044591 hydrogen peroxide decreases expression ISO ERBB2 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of ERBB2 mRNA CTD PMID:12419474 hydroquinone decreases expression ISO ERBB2 (Homo sapiens) 6480464 hydroquinone results in decreased expression of ERBB2 mRNA CTD PMID:22245671 Indeno[1,2,3-cd]pyrene decreases expression ISO ERBB2 (Homo sapiens) 6480464 indeno(1 more ... CTD PMID:21635667 indometacin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ERBB2 mRNA CTD PMID:28628672 irinotecan affects expression EXP 6480464 Irinotecan affects the expression of ERBB2 mRNA CTD PMID:20097248 iron(2+) sulfate (anhydrous) multiple interactions ISO ERBB2 (Homo sapiens) 6480464 ferrous sulfate inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] and ferrous sulfate inhibits the reaction [Quercetin results in decreased expression of and results in increased ubiquitination of ERBB2 protein] CTD PMID:18655187 kahweol multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [kahweol results in decreased expression of ERBB2 mRNA] more ... CTD PMID:30205135 kahweol decreases expression ISO ERBB2 (Homo sapiens) 6480464 kahweol results in decreased expression of ERBB2 mRNA and kahweol results in decreased expression of ERBB2 protein CTD PMID:30205135 L-methionine multiple interactions ISO Erbb2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ERBB2 mRNA CTD PMID:20938992 lactacystin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 lactacystin inhibits the reaction [Dronabinol results in decreased expression of ERBB2 protein] CTD PMID:30733293 lapatinib multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Lapatinib results in decreased susceptibility to Lapatinib] which results in increased phosphorylation of ERBB2 protein more ... CTD PMID:20701607 more ... lapatinib decreases phosphorylation ISO Erbb2 (Mus musculus) 6480464 lapatinib results in decreased phosphorylation of ERBB2 protein CTD PMID:20197467 lapatinib decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 lapatinib results in decreased phosphorylation of ERBB2 protein CTD PMID:20701607 and PMID:26643609 lapatinib decreases expression ISO ERBB2 (Homo sapiens) 6480464 lapatinib results in decreased expression of ERBB2 protein CTD PMID:16091755 lapatinib decreases activity ISO ERBB2 (Homo sapiens) 6480464 lapatinib results in decreased activity of ERBB2 protein CTD PMID:15665275 more ... lead(0) decreases expression ISO ERBB2 (Homo sapiens) 6480464 Lead results in decreased expression of ERBB2 mRNA CTD PMID:19921347 lignan decreases expression ISO ERBB2 (Homo sapiens) 6480464 Lignans results in decreased expression of ERBB2 protein CTD PMID:15897583 linuron multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 lithium chloride multiple interactions ISO ERBB2 (Homo sapiens) 6480464 Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CXCL8 mRNA]] and Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of CXCL8 protein]] CTD PMID:33396024 LY294002 multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Cisplatin] more ... CTD PMID:12439862 more ... LY294002 decreases expression ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ERBB2 mRNA CTD PMID:30205135 masoprocol multiple interactions ISO ERBB2 (Homo sapiens) 6480464 Masoprocol inhibits the reaction [IGF1 protein results in increased phosphorylation of ERBB2 protein] CTD PMID:18645000 mechlorethamine decreases expression ISO ERBB2 (Homo sapiens) 6480464 Mechlorethamine results in decreased expression of ERBB2 protein CTD PMID:17932452 mercaptopurine decreases expression EXP 6480464 Mercaptopurine results in decreased expression of ERBB2 mRNA CTD PMID:23358152 methotrexate affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to Methotrexate CTD PMID:10327070 methotrexate increases expression ISO ERBB2 (Homo sapiens) 6480464 Methotrexate results in increased expression of ERBB2 mRNA CTD PMID:21678067 mitoxantrone multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Mitoxantrone] more ... CTD PMID:21712253 mitoxantrone decreases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 results in decreased susceptibility to Mitoxantrone CTD PMID:21712253 MK-2206 increases expression ISO ERBB2 (Homo sapiens) 6480464 MK 2206 results in increased expression of ERBB2 protein CTD PMID:27897231 MK-2206 multiple interactions ISO ERBB2 (Homo sapiens) 6480464 platycodin D inhibits the reaction [MK 2206 results in increased expression of ERBB2 protein] CTD PMID:27897231 N-acetylcysteamine multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-acetamidoethanethiol analog results in decreased activity of and results in decreased phosphorylation of ERBB2 protein CTD PMID:20058253 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO ERBB2 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Berberine results in decreased expression of ERBB2 protein] more ... CTD PMID:18655187 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO ERBB2 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB2 mRNA and benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB2 protein CTD PMID:20332299 and PMID:31806706 N-ethyl-N-nitrosourea increases mutagenesis EXP 6480464 Ethylnitrosourea results in increased mutagenesis of ERBB2 gene CTD PMID:16651423 N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO ERBB2 (Homo sapiens) 6480464 Methylnitronitrosoguanidine results in increased expression of ERBB2 mRNA CTD PMID:12634122 nitrogen mustard decreases expression ISO ERBB2 (Homo sapiens) 6480464 Nitrogen Mustard Compounds results in decreased expression of ERBB2 mRNA CTD PMID:16417271 orlistat affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to orlistat CTD PMID:15870086 orlistat affects localization ISO ERBB2 (Homo sapiens) 6480464 orlistat affects the localization of ERBB2 protein CTD PMID:15870086 orlistat decreases expression ISO ERBB2 (Homo sapiens) 6480464 orlistat results in decreased expression of ERBB2 mRNA and orlistat results in decreased expression of ERBB2 protein CTD PMID:15870086 Oxyfluorfen affects binding ISO ERBB2 (Homo sapiens) 6480464 oxyfluorofen binds to ERBB2 protein CTD PMID:32278787 ozone multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ERBB2 mRNA more ... CTD PMID:22196529 more ... paclitaxel decreases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in decreased susceptibility to Paclitaxel and ERBB2 results in decreased susceptibility to Paclitaxel CTD PMID:21712253 and PMID:25866362 paclitaxel affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to Paclitaxel CTD PMID:10327070 paclitaxel multiple interactions ISO ERBB2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Paclitaxel] more ... CTD PMID:16580691 more ... palmatine affects binding ISO ERBB2 (Homo sapiens) 6480464 palmatine binds to ERBB2 protein CTD PMID:35997646 paracetamol decreases expression ISO ERBB2 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ERBB2 mRNA CTD PMID:21420995 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of ERBB2 mRNA CTD PMID:33387578 paracetamol multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB2 mRNA CTD PMID:25607892 paraquat multiple interactions ISO ERBB2 (Homo sapiens) 6480464 NFE2L2 protein affects the reaction [ERBB2 protein results in decreased susceptibility to Paraquat] CTD PMID:25467193 paraquat decreases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in decreased susceptibility to Paraquat CTD PMID:25467193 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of ERBB2 mRNA CTD PMID:18692542 perfluorooctanoic acid decreases expression ISO ERBB2 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of ERBB2 protein CTD PMID:26879310 permethrin increases activity ISO ERBB2 (Homo sapiens) 6480464 Permethrin results in increased activity of ERBB2 protein CTD PMID:11222871 phenylmercury acetate decreases expression ISO ERBB2 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of ERBB2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ERBB2 mRNA CTD PMID:27188386 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of ERBB2 mRNA CTD PMID:8603490 phorbol 13-acetate 12-myristate multiple interactions ISO ERBB2 (Homo sapiens) 6480464 PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ERBB2 protein] CTD PMID:20479004 phorbol 13-acetate 12-myristate increases expression ISO ERBB2 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of ERBB2 protein CTD PMID:20479004 Pirarubicin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with pirarubicin co-treated with Fluorouracil] CTD PMID:15940066 platycodin D decreases expression ISO ERBB2 (Homo sapiens) 6480464 platycodin D results in decreased expression of ERBB2 protein CTD PMID:27897231 platycodin D multiple interactions ISO ERBB2 (Homo sapiens) 6480464 platycodin D inhibits the reaction [MK 2206 results in increased expression of ERBB2 protein] CTD PMID:27897231 prochloraz multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 procymidone multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 purine-6-thiol decreases expression EXP 6480464 Mercaptopurine results in decreased expression of ERBB2 mRNA CTD PMID:23358152 quercetin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Deoxyglucose co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein more ... CTD PMID:12888923 and PMID:18655187 quercetin increases expression ISO ERBB2 (Homo sapiens) 6480464 Quercetin results in increased expression of ERBB2 mRNA CTD PMID:14715546 quercetin decreases expression ISO ERBB2 (Homo sapiens) 6480464 Quercetin results in decreased expression of ERBB2 protein CTD PMID:15741050 quercetin decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 Quercetin results in decreased phosphorylation of ERBB2 protein CTD PMID:18655187 quinazolines decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 Quinazolines analog results in decreased phosphorylation of ERBB2 protein CTD PMID:10753475 rac-lactic acid decreases expression ISO ERBB2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ERBB2 mRNA CTD PMID:30851411 raloxifene decreases response to substance ISO Erbb2 (Mus musculus) 6480464 ERBB2 protein results in decreased susceptibility to Raloxifene Hydrochloride CTD PMID:16609042 reparixin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 reparixin affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which affects the phosphorylation of ERBB2 protein] CTD PMID:33396024 reserpine increases response to substance EXP 6480464 ERBB2 protein results in increased susceptibility to Reserpine CTD PMID:8093862 resveratrol multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in decreased expression of ERBB2 mRNA more ... CTD PMID:16488535 more ... resveratrol decreases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 resveratrol results in decreased phosphorylation of ERBB2 protein CTD PMID:20729295 resveratrol decreases expression ISO Erbb2 (Mus musculus) 6480464 resveratrol results in decreased expression of ERBB2 CTD PMID:15688416 resveratrol increases expression ISO ERBB2 (Homo sapiens) 6480464 resveratrol results in increased expression of ERBB2 mRNA and resveratrol results in increased expression of ERBB2 protein CTD PMID:16488535 resveratrol decreases expression ISO ERBB2 (Homo sapiens) 6480464 resveratrol results in decreased expression of ERBB2 more ... CTD PMID:15688416 more ... Rhein decreases expression ISO ERBB2 (Homo sapiens) 6480464 rhein results in decreased expression of ERBB2 protein CTD PMID:21457705 risperidone increases phosphorylation EXP 6480464 Risperidone results in increased phosphorylation of ERBB2 protein CTD PMID:26961615 romidepsin decreases expression ISO ERBB2 (Homo sapiens) 6480464 romidepsin results in decreased expression of ERBB2 protein CTD PMID:15014036 SB 203580 multiple interactions ISO ERBB2 (Homo sapiens) 6480464 SB 203580 inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CXCL8 mRNA]] and SB 203580 inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of CXCL8 protein]] CTD PMID:33396024 SB 431542 multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ERBB2 mRNA CTD PMID:27188386 selenium atom increases expression ISO ERBB2 (Homo sapiens) 6480464 Selenium results in increased expression of ERBB2 mRNA CTD PMID:19244175 selenium atom multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in increased expression of ERBB2 mRNA CTD PMID:19244175 silicon dioxide decreases expression ISO ERBB2 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of ERBB2 mRNA CTD PMID:25895662 sodium arsenate multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of ERBB2 mRNA CTD PMID:32525701 sodium arsenite increases expression ISO ERBB2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of ERBB2 mRNA CTD PMID:32599262 sodium arsenite decreases expression ISO Erbb2 (Mus musculus) 6480464 sodium arsenite results in decreased expression of ERBB2 mRNA CTD PMID:37682722 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of ERBB2 mRNA CTD PMID:11241755 sodium arsenite increases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 sodium arsenite results in increased phosphorylation of ERBB2 protein CTD PMID:20043101 more ... sodium arsenite affects expression ISO ERBB2 (Homo sapiens) 6480464 sodium arsenite affects the expression of ERBB2 protein CTD PMID:17384772 sodium arsenite multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of and affects the phosphorylation of ERBB2 protein more ... CTD PMID:15734884 more ... SR 144528 multiple interactions ISO ERBB2 (Homo sapiens) 6480464 SR 144528 inhibits the reaction [Dronabinol inhibits the reaction [ERBB2 protein binds to CNR2 protein]] more ... CTD PMID:30733293 sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of ERBB2 mRNA CTD PMID:30047161 sulindac sulfide multiple interactions ISO ERBB2 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of ERBB2 protein] CTD PMID:20332299 sulindac sulfide decreases expression ISO ERBB2 (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of ERBB2 protein CTD PMID:20332299 sulindac sulfone decreases expression ISO ERBB2 (Homo sapiens) 6480464 sulindac sulfone results in decreased expression of ERBB2 protein CTD PMID:20332299 tamoxifen multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [ERBB2 protein results in increased activity of ESR1 protein] which results in decreased susceptibility to Tamoxifen and ERBB2 protein inhibits the reaction [PA2G4 protein results in increased susceptibility to Tamoxifen] CTD PMID:20179226 and PMID:20379846 tamoxifen decreases response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in decreased susceptibility to Tamoxifen CTD PMID:15665275 more ... tamoxifen increases phosphorylation ISO ERBB2 (Homo sapiens) 6480464 Tamoxifen results in increased phosphorylation of ERBB2 protein CTD PMID:17157789 tamoxifen increases phosphorylation ISO Erbb2 (Mus musculus) 6480464 Tamoxifen results in increased phosphorylation of ERBB2 protein CTD PMID:21138602 tamoxifen increases expression ISO Erbb2 (Mus musculus) 6480464 Tamoxifen results in increased expression of ERBB2 protein CTD PMID:21138602 tanespimycin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 tanespimycin results in increased degradation of and results in decreased expression of ERBB2 protein CTD PMID:16061882 tanespimycin decreases expression ISO ERBB2 (Homo sapiens) 6480464 tanespimycin results in decreased expression of ERBB2 protein CTD PMID:24784839 and PMID:34291863 temozolomide increases expression ISO ERBB2 (Homo sapiens) 6480464 Temozolomide results in increased expression of ERBB2 mRNA CTD PMID:31758290 tephrosin multiple interactions ISO ERBB2 (Homo sapiens) 6480464 Chloroquine inhibits the reaction [tephrosin results in increased degradation of ERBB2 protein] more ... CTD PMID:20056314 tephrosin affects localization ISO ERBB2 (Homo sapiens) 6480464 tephrosin affects the localization of ERBB2 protein CTD PMID:20056314 tert-butyl hydroperoxide decreases expression ISO ERBB2 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of ERBB2 mRNA CTD PMID:15336504 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of ERBB2 mRNA CTD PMID:33387578 tetraphene decreases expression ISO ERBB2 (Homo sapiens) 6480464 benz(a)anthracene results in decreased expression of ERBB2 mRNA CTD PMID:21635667 thalidomide multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [ERBB2 protein co-treated with PIK3CA protein mutant form] results in increased susceptibility to Thalidomide metabolite CTD PMID:28745489 Thiotepa affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to Thiotepa CTD PMID:10327070 Thiotepa multiple interactions ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Thiotepa co-treated with Carboplatin] CTD PMID:16446318 titanium dioxide decreases expression ISO Erbb2 (Mus musculus) 6480464 titanium dioxide results in decreased expression of ERBB2 mRNA CTD PMID:23409001 titanium dioxide multiple interactions ISO Erbb2 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ERBB2 mRNA CTD PMID:29950665 tributylstannane increases expression ISO Erbb2 (Mus musculus) 6480464 tributyltin results in increased expression of ERBB2 mRNA CTD PMID:31939706 trichloroethene decreases expression ISO Erbb2 (Mus musculus) 6480464 Trichloroethylene results in decreased expression of ERBB2 mRNA CTD PMID:15363585 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of ERBB2 mRNA CTD PMID:33387578 trimellitic anhydride decreases expression ISO Erbb2 (Mus musculus) 6480464 trimellitic anhydride results in decreased expression of ERBB2 mRNA CTD PMID:19042947 tyrphostin AG 1478 multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [RTKI cpd co-treated with AG-879] results in decreased phosphorylation of ERBB2 protein CTD PMID:18618485 undecane decreases expression EXP 6480464 undecane results in decreased expression of ERBB2 protein CTD PMID:17337753 urethane decreases expression ISO ERBB2 (Homo sapiens) 6480464 Urethane results in decreased expression of ERBB2 mRNA CTD PMID:28818685 valproic acid decreases expression ISO ERBB2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ERBB2 mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO ERBB2 (Homo sapiens) 6480464 Valproic Acid affects the expression of ERBB2 mRNA CTD PMID:25979313 vincaleukoblastine affects response to substance ISO ERBB2 (Homo sapiens) 6480464 ERBB2 protein affects the susceptibility to Vinblastine CTD PMID:10327070 vinclozolin multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 vitamin E multiple interactions ISO ERBB2 (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in increased expression of ERBB2 mRNA CTD PMID:19244175 vorinostat decreases expression ISO ERBB2 (Homo sapiens) 6480464 vorinostat results in decreased expression of ERBB2 mRNA and vorinostat results in decreased expression of ERBB2 protein CTD PMID:17218635 and PMID:27188386 vorinostat multiple interactions ISO ERBB2 (Homo sapiens) 6480464 vorinostat results in increased ubiquitination of and results in increased degradation of and results in decreased expression of ERBB2 protein CTD PMID:16144943