Gene: Erbb2 (erb-b2 receptor tyrosine kinase 2) Rattus norvegicus
Symbol: Erbb2
Name: erb-b2 receptor tyrosine kinase 2
Description: ENCODES a protein that exhibits glycoprotein binding; Hsp90 protein binding; protein heterodimerization activity; INVOLVED IN estrous cycle; glial cell differentiation; liver development; PARTICIPATES IN mitogen activated protein kinase signaling pathway; Ras mediated signaling pathway; altered epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH increased metastatic potential; ASSOCIATED WITH Diabetic Cardiomyopathies; Heart Failure; Mammary Neoplasms, Experimental; FOUND IN apical plasma membrane; basal plasma membrane; basolateral plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; 3H-1,2-dithiole-3-thione
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); C-erbB-2; epidermal growth factor receptor-related protein; NEU proto-oncogene; p185erbB2; p185neu; proto-oncogene c-ErbB-2; proto-oncogene NEU; receptor tyrosine-protein kinase erbB-2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01086,367,596 - 86,391,728 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01086,163,531 - 86,187,663 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41087,219,157 - 87,242,919 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11087,233,617 - 87,256,603 (+)NCBI
Celera1082,158,844 - 82,182,518 (+)NCBI
Cytogenetic Map10q32.1NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Erbb2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2561
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE