Gene: Prkdc (protein kinase, DNA activated, catalytic polypeptide) Rattus norvegicus
Symbol: Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Description: ENCODES a protein that exhibits DNA-dependent protein kinase activity (ortholog); double-stranded DNA binding (ortholog); enzyme binding (ortholog); INVOLVED IN immunoglobulin production; negative regulation of cellular senescence; negative regulation of immunoglobulin production; PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH IMMUNODEFICIENCY 26 WITH OR WITHOUT NEUROLOGIC ABNORMALITIES (ortholog); Severe Combined Immunodeficiency (ortholog); FOUND IN DNA-dependent protein kinase-DNA ligase 4 complex (ortholog); membrane (ortholog); nonhomologous end joining complex (ortholog); INTERACTS WITH dibutyl phthalate; furan; nickel dichloride
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA-dependent protein kinase catalytic subunit; LOC360748; MGC189093
Orthologs:
Is Marker For: Strains:   F344-Prkdcem1Kyo   F344-Prkdcem2KyoIl2rgem6Kyo   TM-Prkdcem4KyoIl2rgem5Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01189,293,547 - 89,510,948 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01192,347,175 - 92,565,022 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41186,951,420 - 87,169,229 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,992,362 - 87,209,825 (-)NCBI
Celera1183,781,535 - 83,998,574 (-)NCBI
Cytogenetic Map11q23NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Prkdc
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1308982
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE