Ptgr2 (prostaglandin reductase 2) - Rat Genome Database

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Gene: Ptgr2 (prostaglandin reductase 2) Rattus norvegicus
Analyze
Symbol: Ptgr2
Name: prostaglandin reductase 2
RGD ID: 1310518
Description: Predicted to enable 15-oxoprostaglandin 13-oxidase activity. Predicted to be involved in prostaglandin metabolic process. Predicted to be located in cytoplasm. Orthologous to human PTGR2 (prostaglandin reductase 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 15-oxoprostaglandin 13-reductase; LOC299194; MGC108784; PRG-2; Zadh1; zinc binding alcohol dehydrogenase, domain containing 1; zinc-binding alcohol dehydrogenase domain-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,662,469 - 109,694,232 (+)NCBIGRCr8
mRatBN7.26103,931,367 - 103,963,113 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,931,409 - 103,963,111 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,093,166 - 104,124,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,392,251 - 104,423,987 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,761,828 - 103,793,565 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,999,832 - 108,031,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,999,846 - 108,031,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06117,514,752 - 117,546,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,349,172 - 108,380,867 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,352,627 - 108,384,321 (+)NCBI
Celera6101,759,837 - 101,791,510 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:18614015   PMID:19000823   PMID:23376485  


Genomics

Comparative Map Data
Ptgr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,662,469 - 109,694,232 (+)NCBIGRCr8
mRatBN7.26103,931,367 - 103,963,113 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,931,409 - 103,963,111 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,093,166 - 104,124,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,392,251 - 104,423,987 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,761,828 - 103,793,565 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,999,832 - 108,031,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,999,846 - 108,031,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06117,514,752 - 117,546,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,349,172 - 108,380,867 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,352,627 - 108,384,321 (+)NCBI
Celera6101,759,837 - 101,791,510 (+)NCBICelera
Cytogenetic Map6q31NCBI
PTGR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,851,831 - 73,885,726 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,851,831 - 73,885,726 (+)EnsemblGRCh38hg38GRCh38
GRCh371474,318,534 - 74,352,429 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,388,424 - 73,421,915 (+)NCBINCBI36Build 36hg18NCBI36
Build 341473,388,426 - 73,421,915NCBI
Celera1454,355,472 - 54,389,115 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1454,485,578 - 54,519,224 (+)NCBIHuRef
CHM1_11474,258,185 - 74,291,756 (+)NCBICHM1_1
T2T-CHM13v2.01468,059,477 - 68,093,373 (+)NCBIT2T-CHM13v2.0
Ptgr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,332,011 - 84,362,606 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,332,006 - 84,362,606 (+)EnsemblGRCm39 Ensembl
GRCm381284,285,237 - 84,315,832 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,285,232 - 84,315,832 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,626,264 - 85,656,782 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361285,175,062 - 85,205,580 (+)NCBIMGSCv36mm8
Celera1285,740,324 - 85,770,857 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.14NCBI
Ptgr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555231,515,017 - 1,549,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555231,519,767 - 1,549,998 (-)NCBIChiLan1.0ChiLan1.0
PTGR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21574,941,609 - 74,981,970 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11474,158,124 - 74,191,783 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01454,410,939 - 54,444,595 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11473,266,484 - 73,299,378 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1473,266,502 - 73,299,378 (+)Ensemblpanpan1.1panPan2
PTGR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1847,095,405 - 47,120,371 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,768,242 - 46,805,297 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0847,313,084 - 47,350,058 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl847,312,781 - 47,350,047 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1846,980,670 - 47,017,709 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,998,391 - 47,035,732 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0847,389,163 - 47,426,127 (+)NCBIUU_Cfam_GSD_1.0
Ptgr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,903,412 - 28,945,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364883,123,304 - 3,166,863 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364883,123,405 - 3,165,556 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl797,174,219 - 97,195,595 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1797,174,143 - 97,195,601 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,928,733 - 102,950,202 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTGR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12451,060,503 - 51,095,762 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2451,060,608 - 51,095,303 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605339,274,452 - 39,312,455 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptgr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473427,687,195 - 27,717,548 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473427,686,993 - 27,716,802 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptgr2
118 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:703
Count of miRNA genes:265
Interacting mature miRNAs:322
Transcripts:ENSRNOT00000058095, ENSRNOT00000059073
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 51 35 19 35 8 11 74 35 40 11 8
Low 6 6 6 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000058095   ⟹   ENSRNOP00000054903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6103,931,423 - 103,963,111 (+)Ensembl
Rnor_6.0 Ensembl6107,999,846 - 108,031,643 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000059073   ⟹   ENSRNOP00000055851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6103,931,409 - 103,958,273 (+)Ensembl
Rnor_6.0 Ensembl6108,009,251 - 108,029,859 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118264   ⟹   ENSRNOP00000080851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6103,931,409 - 103,963,079 (+)Ensembl
RefSeq Acc Id: NM_001015009   ⟹   NP_001015009
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
Rnor_6.06107,999,846 - 108,031,645 (+)NCBI
Rnor_5.06117,514,752 - 117,546,565 (-)NCBI
RGSC_v3.46108,349,172 - 108,380,867 (+)RGD
Celera6101,759,837 - 101,791,510 (+)RGD
Sequence:
RefSeq Acc Id: NM_001399426   ⟹   NP_001386355
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
RefSeq Acc Id: NM_001399433   ⟹   NP_001386362
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
RefSeq Acc Id: NR_174185
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
RefSeq Acc Id: NR_174186
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
RefSeq Acc Id: XM_006240327   ⟹   XP_006240389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,469 - 109,694,156 (+)NCBI
mRatBN7.26103,931,367 - 103,963,113 (+)NCBI
Rnor_6.06107,999,835 - 108,031,645 (+)NCBI
Rnor_5.06117,514,752 - 117,546,565 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240329   ⟹   XP_006240391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,674,256 - 109,694,156 (+)NCBI
mRatBN7.26103,943,200 - 103,963,113 (+)NCBI
Rnor_6.06108,011,662 - 108,031,645 (+)NCBI
Rnor_5.06117,514,752 - 117,546,565 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112026   ⟹   XP_038967954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,496 - 109,684,476 (+)NCBI
mRatBN7.26103,931,402 - 103,953,433 (+)NCBI
RefSeq Acc Id: XM_063261733   ⟹   XP_063117803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,497 - 109,694,156 (+)NCBI
RefSeq Acc Id: XM_063261734   ⟹   XP_063117804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,497 - 109,694,156 (+)NCBI
RefSeq Acc Id: XM_063261735   ⟹   XP_063117805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,469 - 109,694,156 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001015009   ⟸   NM_001015009
- Peptide Label: isoform 2
- UniProtKB: Q5BK81 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240389   ⟸   XM_006240327
- Peptide Label: isoform X1
- UniProtKB: Q5BK81 (UniProtKB/Swiss-Prot),   A6JDT8 (UniProtKB/TrEMBL),   A0A8L2QSN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240391   ⟸   XM_006240329
- Peptide Label: isoform X2
- UniProtKB: A6JDU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054903   ⟸   ENSRNOT00000058095
RefSeq Acc Id: ENSRNOP00000055851   ⟸   ENSRNOT00000059073
RefSeq Acc Id: XP_038967954   ⟸   XM_039112026
- Peptide Label: isoform X4
- UniProtKB: A6JDU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000080851   ⟸   ENSRNOT00000118264
RefSeq Acc Id: NP_001386362   ⟸   NM_001399433
- Peptide Label: isoform 3
- UniProtKB: A0A8I6G545 (UniProtKB/TrEMBL),   A0A8L2QSN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386355   ⟸   NM_001399426
- Peptide Label: isoform 1
- UniProtKB: Q5BK81 (UniProtKB/Swiss-Prot),   A6JDT8 (UniProtKB/TrEMBL),   A0A8L2QSN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117805   ⟸   XM_063261735
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063117803   ⟸   XM_063261733
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063117804   ⟸   XM_063261734
- Peptide Label: isoform X1
Protein Domains
Alcohol dehydrogenase-like C-terminal   Oxidoreductase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK81-F1-model_v2 AlphaFold Q5BK81 1-351 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694722
Promoter ID:EPDNEW_R5246
Type:initiation region
Name:Ptgr2_1
Description:prostaglandin reductase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06107,999,837 - 107,999,897EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310518 AgrOrtholog
BioCyc Gene G2FUF-36828 BioCyc
Ensembl Genes ENSRNOG00000038166 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058095 ENTREZGENE
  ENSRNOT00000058095.4 UniProtKB/Swiss-Prot
  ENSRNOT00000059073.5 UniProtKB/TrEMBL
  ENSRNOT00000118264 ENTREZGENE
  ENSRNOT00000118264.1 UniProtKB/TrEMBL
Gene3D-CATH Medium-chain alcohol dehydrogenases, catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7189599 IMAGE-MGC_LOAD
InterPro ADH-like_C UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  ADH_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MDR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTGR2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:299194 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108784 IMAGE-MGC_LOAD
NCBI Gene 299194 ENTREZGENE
PANTHER PROSTAGLANDIN REDUCTASE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR43205 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ADH_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptgr2 PhenoGen
RatGTEx ENSRNOG00000038166 RatGTEx
Superfamily-SCOP SSF50129 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6G545 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QSN3 ENTREZGENE, UniProtKB/TrEMBL
  A6JDT8 ENTREZGENE, UniProtKB/TrEMBL
  A6JDU4 ENTREZGENE, UniProtKB/TrEMBL
  A6JDU5 ENTREZGENE, UniProtKB/TrEMBL
  PTGR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Ptgr2  prostaglandin reductase 2  Zadh1  zinc binding alcohol dehydrogenase, domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Zadh1  zinc binding alcohol dehydrogenase, domain containing 1  Zadh1_predicted  zinc binding alcohol dehydrogenase, domain containing 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Zadh1_predicted  zinc binding alcohol dehydrogenase, domain containing 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED