Gene: Ace2 (angiotensin I converting enzyme 2) Rattus norvegicus
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Symbol: Ace2
Name: angiotensin I converting enzyme 2
Description: ENCODES a protein that exhibits carboxypeptidase activity; endopeptidase activity (ortholog); glycoprotein binding (ortholog); INVOLVED IN maternal process involved in female pregnancy; negative regulation of ERK1 and ERK2 cascade; negative regulation of smooth muscle cell proliferation; PARTICIPATES IN apelin signaling pathway; renin-angiotensin cascade pathway; ASSOCIATED WITH Cardiac Fibrosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; FOUND IN extracellular space; membrane; cell surface (ortholog); INTERACTS WITH aflatoxin B1; bisphenol A; cadmium dichloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; renal angiotensin-converting enzyme 2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X32,050,734 - 32,095,860 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0X32,422,286 - 32,469,137 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4X51,051,758 - 51,096,036 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X51,105,228 - 51,149,505 (-)NCBI
CeleraX30,638,123 - 30,683,403 (-)NCBI
Cytogenetic MapXq14NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Protein Structures
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
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RGD Object Information
RGD ID: 728890
Created: 2003-11-21
Species: Rattus norvegicus
Last Modified: 2016-11-18
Status: ACTIVE