Gene: Casp6 (caspase 6) Rattus norvegicus
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Symbol: Casp6
Name: caspase 6
Description: ENCODES a protein that exhibits endopeptidase activity; cysteine-type endopeptidase activity involved in execution phase of apoptosis (ortholog); identical protein binding (ortholog); INVOLVED IN acute inflammatory response to non-antigenic stimulus; lens development in camera-type eye; positive regulation of apoptotic process; PARTICIPATES IN apoptotic cell death pathway; ASSOCIATED WITH Brain Ischemia; brain ischemia; Diabetes Mellitus, Experimental; FOUND IN cytoplasm; cytosol; nucleus; INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apoptotic protease Mch-2; CASP-6; caspase-6; Mch2; MGC93335
Orthologs:
Homo sapiens (human) : CASP6 (caspase 6)  HGNC
Chinchilla lanigera (long-tailed chinchilla) : Casp6 (caspase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP6 (caspase 6)
Canis lupus familiaris (dog) : CASP6 (caspase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp6 (caspase 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02235,341,326 - 235,353,715 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02249,539,649 - 249,552,032 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42227,361,538 - 227,373,844 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12227,348,217 - 227,360,523 (+)NCBI
Celera2210,748,422 - 210,760,763 (+)NCBI
Cytogenetic Map2q43NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Casp6
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 70967
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE