Gene: Pdgfrb (platelet derived growth factor receptor beta) Rattus norvegicus
Symbol: Pdgfrb
Name: platelet derived growth factor receptor beta
Description: ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding; platelet-derived growth factor-activated receptor activity; protein tyrosine kinase activity; INVOLVED IN cellular response to platelet-derived growth factor stimulus; glycosaminoglycan biosynthetic process; inner ear development; PARTICIPATES IN platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Cardiomegaly; Cholestasis, Extrahepatic; Diabetes Mellitus, Experimental; FOUND IN apical plasma membrane; cell surface; cytoplasm; INTERACTS WITH (+)-alpha-tocopherol; (+)-dihydromyricetin; (-)-epigallocatechin 3-gallate
Type: protein-coding
Also known as: beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; PDGF-R-beta; PDGFR-1; PDGFR-beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01856,364,587 - 56,406,381+NCBI
Rat Cytogenetic Map18q12.1 NCBI
RGSC Genome Assembly v5.01855,596,682 - 55,637,692+NCBI
RGSC Genome Assembly v3.41857,014,475 - 57,053,581+NCBI
Rat Celera Assembly1852,652,411 - 52,691,218+NCBI
Genome Assembly 3.11857,086,706 - 57,125,813+NCBI

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Disease Annotations
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Gene Ontology Annotations
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References - curated
References - uncurated
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Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pdgfrb
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RGD Object Information
RGD ID: 3285
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-01-26
Status: ACTIVE