Gene: Pdgfrb (platelet derived growth factor receptor, beta polypeptide)  Rattus norvegicus
Symbol: Pdgfrb
Name: platelet derived growth factor receptor, beta polypeptide
Description: ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding; platelet-derived growth factor-activated receptor activity; protein tyrosine kinase activity; INVOLVED IN cellular response to platelet-derived growth factor stimulus; glycosaminoglycan biosynthetic process; inner ear development; PARTICIPATES IN transforming growth factor-beta signaling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH Cardiomegaly; Diabetes Mellitus, Experimental; Hyperoxia; FOUND IN apical plasma membrane; cytoplasm; nucleus; INTERACTS WITH (+)-dihydromyricetin; (-)-epigallocatechin 3-gallate; (S)-nicotine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; PDGF-R-beta; PDGFR-1; PDGFR-beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta
Orthologs: Homo sapiens : PDGFRB (platelet-derived growth factor receptor, beta polypeptide)  HGNC
Mus musculus : Pdgfrb (platelet derived growth factor receptor, beta polypeptide)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map18q12.1 NCBI
RGSC Genome Assembly v5.01855,596,758 - 55,637,692+NCBI
RGSC Genome Assembly v3.41857,014,475 - 57,053,581+NCBI
Rat Celera Assembly1852,652,411 - 52,691,218+NCBI
Genome Assembly 3.11857,086,706 - 57,125,813+NCBI
Model

Launch Genome Browser (GBrowse)

Annotation    (Toggle Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Pdgfrb
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3285
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE



Contact Us |  About Us |  Jobs at RGD