Pitx2 (paired-like homeodomain 2)

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Keyword

Gene: Pitx2 (paired-like homeodomain 2) Rattus norvegicus

Symbol:

Pitx2

Name:

paired-like homeodomain 2

Description:

ENCODES a protein that exhibits RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; chromatin binding (ortholog); INVOLVED IN brain development; female gonad development; male gonad development; PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH Hypothyroidism; Polycystic Kidney, Autosomal Dominant; AXENFELD-RIEGER SYNDROME, TYPE 1 (ortholog); FOUND IN nucleus; cytoplasm (ortholog); transcription factor complex (ortholog); INTERACTS WITH 1,3-dinitrobenzene; all-trans-retinoic acid; ammonium chloride

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

homeobox protein PITX2; homeodomain transcription factor 2; paired-like homeodomain transcription factor 2; pituitary homeobox 2; Pitx2c; Ptx2; rPtx2

Orthologs:

Homo sapiens : PITX2 (paired-like homeodomain 2) HGNC
Mus musculus : Pitx2 (paired-like homeodomain transcription factor 2) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	2	q42		NCBI
RGSC Genome Assembly v5.0	2	252,929,195 - 252,948,179	+	NCBI
RGSC Genome Assembly v3.4	2	226,581,170 - 226,601,319	+	NCBI
Rat Celera Assembly	2	210,013,296 - 210,033,592	+	NCBI
Genome Assembly 3.1	2	226,567,811 - 226,587,999	+	NCBI