Gene: Pitx2 (paired-like homeodomain 2) Rattus norvegicus
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Symbol: Pitx2
Name: paired-like homeodomain 2
Description: ENCODES a protein that exhibits RNA polymerase II core promoter proximal region sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; chromatin binding (ortholog); INVOLVED IN brain development; female gonad development; male gonad development; PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH Hypothyroidism; Polycystic Kidney, Autosomal Dominant; Axenfeld-Rieger Syndrome, Type 1 (ortholog); FOUND IN nucleus; cytoplasm (ortholog); transcription factor complex (ortholog); INTERACTS WITH 1,3-dinitrobenzene; all-trans-retinoic acid; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeobox protein PITX2; homeodomain transcription factor 2; paired-like homeodomain transcription factor 2; pituitary homeobox 2; Pitx-2; Pitx2c; Ptx2; rPtx2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02233,602,732 - 233,621,059 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02252,929,195 - 252,948,179 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42226,581,170 - 226,601,319 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12226,567,811 - 226,587,999 (+)NCBI
Celera2210,013,296 - 210,033,592 (+)NCBI
Cytogenetic Map2q42NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pitx2
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
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Vista + UCSC

RGD Object Information
RGD ID: 3331
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-11-22
Status: ACTIVE