Gene: Raf1 (v-raf-leukemia viral oncogene 1) Rattus norvegicus
Symbol: Raf1
Name: v-raf-leukemia viral oncogene 1
Description: ENCODES a protein that exhibits ATP binding; MAP kinase kinase kinase activity; mitogen-activated protein kinase kinase binding; INVOLVED IN heart development; MAPK cascade; protein phosphorylation; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; ceramide signaling pathway; ASSOCIATED WITH Ischemia (ortholog); LEOPARD Syndrome (ortholog); LEOPARD syndrome, 2 (ortholog); FOUND IN cytoplasm; plasma membrane; cell (ortholog); INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
Also known as: C-RAF; cRaf; Murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV); proto-oncogene c-RAF; RAF proto-oncogene serine/threonine-protein kinase; raf-1; v-raf-1 murine leukemia viral oncogene homolog 1
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: suggests misassembly
RGSC Genome Assembly v6.04147,532,040 - 147,592,769-NCBI
Rat Cytogenetic Map4q42 NCBI
RGSC Genome Assembly v5.04210,819,148 - 210,878,226-NCBI
RGSC Genome Assembly v3.44151,752,583 - 151,775,609-NCBI
Rat Celera Assembly4137,570,499 - 137,631,125-NCBI
Genome Assembly 3.14151,997,425 - 152,020,450-NCBI

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Disease Annotations
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References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Raf1
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RGD Object Information
RGD ID: 3531
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE