Gene: Raf1 (v-raf-leukemia viral oncogene 1) Rattus norvegicus
Symbol: Raf1
Name: v-raf-leukemia viral oncogene 1
Description: ENCODES a protein that exhibits ATP binding; MAP kinase kinase kinase activity; mitogen-activated protein kinase kinase binding; INVOLVED IN activation of MAPKK activity; heart development; MAPK cascade; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; ceramide signaling pathway; ASSOCIATED WITH Ischemia (ortholog); LEOPARD Syndrome (ortholog); LEOPARD syndrome, 2 (ortholog); FOUND IN cytoplasm; plasma membrane; cytosol (ortholog); INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-RAF; cRaf; Murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV); proto-oncogene c-RAF; RAF proto-oncogene serine/threonine-protein kinase; raf-1; v-raf-1 murine leukemia viral oncogene homolog 1
Orthologs:
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.04147,532,040 - 147,592,769-NCBI
Rat Cytogenetic Map4q42 NCBI
RGSC Genome Assembly v5.04210,819,148 - 210,878,226-NCBI
RGSC Genome Assembly v3.44151,752,583 - 151,775,609-NCBI
Rat Celera Assembly4137,570,499 - 137,631,125-NCBI
Genome Assembly 3.14151,997,425 - 152,020,450-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Raf1
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
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Vista + UCSC

RGD Object Information
RGD ID: 3531
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-12-02
Status: ACTIVE