Gene: Raf1 (Raf-1 proto-oncogene, serine/threonine kinase) Rattus norvegicus
Symbol: Raf1
Name: Raf-1 proto-oncogene, serine/threonine kinase
Description: ENCODES a protein that exhibits ATP binding; MAP kinase kinase kinase activity; mitogen-activated protein kinase kinase binding; INVOLVED IN heart development; MAPK cascade; protein phosphorylation; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; ceramide signaling pathway; ASSOCIATED WITH Cardiomyopathy, Dilated (ortholog); Cardiomyopathy, Hypertrophic (ortholog); Cardiomyopathy, Hypertrophic, Familial (ortholog); FOUND IN cytoplasm; plasma membrane; cytosol (ortholog); INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-RAF; cRaf; Murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV); proto-oncogene c-RAF; RAF proto-oncogene serine/threonine-protein kinase; raf-1; v-raf-1 murine leukemia viral oncogene homolog 1; v-raf-leukemia viral oncogene 1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04147,532,040 - 147,592,769 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.04210,819,148 - 210,878,226 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.44151,752,583 - 151,775,609 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14151,997,425 - 152,020,450 (-)NCBI
Celera4137,570,499 - 137,631,125 (-)NCBI
Cytogenetic Map4q42NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Raf1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3531
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-05-10
Status: ACTIVE