Gene: Serpine2 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2)  Rattus norvegicus

Symbol: Serpine2
Name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
Description: ENCODES a protein that exhibits heparin binding; serine-type endopeptidase inhibitor activity; glycosaminoglycan binding (ortholog); INVOLVED IN dense core granule biogenesis; embryo implantation; negative regulation of blood coagulation; ASSOCIATED WITH Brain Edema; Hypertension; Reperfusion Injury; FOUND IN extracellular space; membrane; neuronal cell body; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; alendronic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GDN; Gdnpn1; glia-derived nexin; Glia-derived nexin/protease nexin I; peptidase inhibitor 7; PI-7; plasminogen activator inhibitor type 1; Pn-1; protease nexin 1; protease nexin I; protease nexin PN-1; serine (or cysteine) peptidase inhibitor, clade E, member 2; serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 2; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1) , member 2; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine (or cysteine) proteinase inhibitor, clade E, member 2 ; serine protease inhibitor 4; serpin E2; serpin peptidase inhibitor, clade E, member 2; Spin4
Orthologs: Homo sapiens : SERPINE2 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2)  HGNC
Mus musculus : Serpine2 (serine (or cysteine) peptidase inhibitor, clade E, member 2)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map9q34 NCBI
RGSC Genome Assembly v5.0985,312,140 - 85,375,551-NCBI
RGSC Genome Assembly v3.4979,091,414 - 79,166,330-NCBI
Rat Celera Assembly978,614,628 - 78,678,321-NCBI
Genome Assembly 3.1979,275,580 - 79,302,222-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Serpine2
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RGD Object Information
RGD ID: 3748
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE