Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | decreases expression | ISO | Rab6b (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of RAB6B mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | multiple interactions | ISO | Rab6b (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of RAB6B mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rab6b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RAB6B mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RAB6B mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of RAB6B protein | CTD | PMID:31675489 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Rab6b (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of RAB6B mRNA | CTD | PMID:20188158 | 4-hydroxyphenyl retinamide | increases expression | ISO | Rab6b (Mus musculus) | 6480464 | Fenretinide results in increased expression of RAB6B mRNA | CTD | PMID:28973697 | all-trans-retinoic acid | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RAB6B mRNA | CTD | PMID:33167477 | antirheumatic drug | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of RAB6B mRNA | CTD | PMID:24449571 | atrazine | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Atrazine results in increased expression of RAB6B mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | Rab6b (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RAB6B mRNA | CTD | PMID:21569818 | benzo[a]pyrene | affects methylation | ISO | RAB6B (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RAB6B promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B protein | CTD | PMID:31199487 and PMID:37690569 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RAB6B mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RAB6B protein | CTD | PMID:31675489 | bisphenol A | increases expression | ISO | Rab6b (Mus musculus) | 6480464 | bisphenol A results in increased expression of RAB6B mRNA | CTD | PMID:32156529 and PMID:34585602 | bisphenol A | increases methylation | ISO | Rab6b (Mus musculus) | 6480464 | bisphenol A results in increased methylation of RAB6B promoter | CTD | PMID:27312807 | Butylbenzyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B protein | CTD | PMID:31199487 and PMID:37690569 | cadmium atom | multiple interactions | ISO | RAB6B (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RAB6B mRNA | CTD | PMID:35301059 | cadmium atom | multiple interactions | ISO | Rab6b (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RAB6B mRNA | CTD | PMID:37325564 | cadmium dichloride | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of RAB6B mRNA | CTD | PMID:21457566 | cadmium dichloride | multiple interactions | ISO | Rab6b (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RAB6B mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | RAB6B (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RAB6B mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of RAB6B mRNA | CTD | PMID:26472689 | cannabidiol | multiple interactions | ISO | RAB6B (Homo sapiens) | 6480464 | [Cuprizone co-treated with Cannabidiol] results in increased expression of RAB6B protein | CTD | PMID:34122009 | carbamazepine | affects expression | ISO | RAB6B (Homo sapiens) | 6480464 | Carbamazepine affects the expression of RAB6B mRNA | CTD | PMID:25979313 | carbon nanotube | decreases expression | ISO | Rab6b (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlorpyrifos | increases expression | ISO | Rab6b (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of RAB6B mRNA | CTD | PMID:32715474 | ciguatoxin CTX1B | affects expression | ISO | Rab6b (Mus musculus) | 6480464 | Ciguatoxins affects the expression of RAB6B mRNA | CTD | PMID:18353800 | cisplatin | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Cisplatin results in increased expression of RAB6B mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | RAB6B (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of RAB6B mRNA | CTD | PMID:27392435 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of RAB6B mRNA | CTD | PMID:26577399 | Cuprizon | multiple interactions | ISO | RAB6B (Homo sapiens) | 6480464 | [Cuprizone co-treated with Cannabidiol] results in increased expression of RAB6B protein | CTD | PMID:34122009 | cyclosporin A | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of RAB6B mRNA | CTD | PMID:27989131 | decabromodiphenyl ether | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of RAB6B protein | CTD | PMID:31675489 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B protein | CTD | PMID:31199487 and PMID:37690569 | diethyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B protein | CTD | PMID:31199487 and PMID:37690569 | diisobutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B protein | CTD | PMID:31199487 and PMID:37690569 | diisononyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B mRNA and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B protein | CTD | PMID:31199487 and PMID:37690569 | dorsomorphin | multiple interactions | ISO | RAB6B (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB6B mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of RAB6B mRNA | CTD | PMID:29803840 | ethanol | multiple interactions | ISO | Rab6b (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of RAB6B mRNA | CTD | PMID:30319688 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of RAB6B mRNA | CTD | PMID:30307764 | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of RAB6B mRNA | CTD | PMID:34044035 | folic acid | multiple interactions | ISO | Rab6b (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of RAB6B mRNA | CTD | PMID:22206623 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of RAB6B mRNA | CTD | PMID:27387713 | gamma-tocopherol | increases expression | ISO | Rab6b (Mus musculus) | 6480464 | Tocopherols results in increased expression of RAB6B mRNA | CTD | PMID:17654050 | genistein | increases expression | ISO | Rab6b (Mus musculus) | 6480464 | Genistein results in increased expression of RAB6B mRNA | CTD | PMID:32186404 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of RAB6B mRNA | CTD | PMID:33387578 | hydrogen peroxide | affects expression | ISO | RAB6B (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of RAB6B mRNA | CTD | PMID:20044591 | hydroquinone O-beta-D-glucopyranoside | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Arbutin results in decreased expression of RAB6B mRNA | CTD | PMID:17103032 | kojic acid | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | kojic acid results in decreased expression of RAB6B mRNA | CTD | PMID:16595896 | lead(0) | affects expression | ISO | RAB6B (Homo sapiens) | 6480464 | Lead affects the expression of RAB6B mRNA | CTD | PMID:28903495 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of RAB6B gene | CTD | PMID:35440735 | N-nitrosodiethylamine | increases expression | ISO | Rab6b (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of RAB6B mRNA | CTD | PMID:17942915 | N-nitrosodiethylamine | multiple interactions | ISO | Rab6b (Mus musculus) | 6480464 | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RAB6B mRNA] | CTD | PMID:17942915 | nickel atom | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Nickel results in decreased expression of RAB6B mRNA | CTD | PMID:24768652 and PMID:25583101 | ozone | multiple interactions | ISO | Rab6b (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of RAB6B mRNA | CTD | PMID:34911549 | paracetamol | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of RAB6B mRNA | CTD | PMID:26690555 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of RAB6B mRNA | CTD | PMID:33387578 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of RAB6B mRNA | CTD | PMID:32680482 | perfluorohexanesulfonic acid | decreases expression | ISO | Rab6b (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of RAB6B mRNA | CTD | PMID:37995155 | phenylmercury acetate | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of RAB6B mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RAB6B (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB6B mRNA | CTD | PMID:27188386 | potassium dichromate | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of RAB6B protein | CTD | PMID:23718831 | SB 431542 | multiple interactions | ISO | RAB6B (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB6B mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of RAB6B mRNA | CTD | PMID:25895662 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of RAB6B mRNA | CTD | PMID:22561333 | sunitinib | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of RAB6B mRNA | CTD | PMID:31533062 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of RAB6B mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | Rab6b (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of RAB6B mRNA | CTD | PMID:23557971 and PMID:27760801 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of RAB6B mRNA | CTD | PMID:30012374 | tocopherol | increases expression | ISO | Rab6b (Mus musculus) | 6480464 | Tocopherols results in increased expression of RAB6B mRNA | CTD | PMID:17654050 | trichostatin A | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | trichostatin A results in increased expression of RAB6B mRNA | CTD | PMID:24935251 | trichostatin A | decreases expression | ISO | RAB6B (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of RAB6B mRNA | CTD | PMID:24935251 | trimellitic anhydride | decreases expression | ISO | Rab6b (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of RAB6B mRNA | CTD | PMID:19042947 | troglitazone | decreases expression | ISO | Rab6b (Mus musculus) | 6480464 | troglitazone results in decreased expression of RAB6B mRNA | CTD | PMID:28973697 | valproic acid | affects expression | ISO | RAB6B (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RAB6B mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | RAB6B (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RAB6B mRNA | CTD | PMID:19101580 more ... | |