Gene: Itgb2 (integrin, beta 2)  Rattus norvegicus

Symbol: Itgb2
Name: integrin, beta 2
Description: ENCODES a protein that exhibits cell adhesion molecule binding; protein complex binding; protein heterodimerization activity; INVOLVED IN aging; cell-cell adhesion; cellular extravasation; PARTICIPATES IN hypoxia inducible factor pathway; integrin mediated signaling pathway; Entamoeba histolyca infection pathway; ASSOCIATED WITH Acute Lung Injury; Arthritis, Experimental; Kidney Reperfusion Injury; FOUND IN cell surface; plasma membrane; membrane (ortholog); INTERACTS WITH 2-nitrotoluene; bromochloroacetic acid; cadmium dichloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cd18; CD18 leukocyte adhesion molecule; integrin beta 2; integrin beta 2 (predicted); integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); Itgb2_predicted; macrophage antigen 1 (mac-1) beta subunit); MGC116306
Orthologs: Homo sapiens : ITGB2 (integrin, beta 2 (complement component 3 receptor 3 and 4 subunit))  HGNC
Mus musculus : Itgb2 (integrin beta 2)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map20p12 NCBI
RGSC Genome Assembly v5.02013,944,190 - 13,981,048-NCBI
RGSC Genome Assembly v3.42011,446,521 - 11,485,009-NCBI
Rat Celera Assembly2012,564,941 - 12,601,097-NCBI
Genome Assembly 3.12011,446,936 - 11,485,236-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Itgb2
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RGD Object Information
RGD ID: 1305581
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE