Gene: H2afx (H2A histone family, member X) Rattus norvegicus
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Symbol: H2afx
Name: H2A histone family, member X
Description: ENCODES a protein that exhibits damaged DNA binding (ortholog); enzyme binding (ortholog); histone binding (ortholog); INVOLVED IN cellular response to gamma radiation; cellular senescence; cerebral cortex development; PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; systemic lupus erythematosus pathway; ASSOCIATED WITH Drug-Induced Liver Injury; hepatic angiomyolipoma; hepatic osteogenic sarcoma; FOUND IN nucleus; centrosome (ortholog); chromatin (ortholog); INTERACTS WITH (-)-ephedrine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC500987; RGD1566119; similar to Histone H2A.x (H2a/x)
Orthologs:
Homo sapiens (human) : H2AFX (H2A histone family member X)  HGNC
Mus musculus (house mouse) : H2afx (H2A histone family, member X)  MGI
Chinchilla lanigera (long-tailed chinchilla) : LOC102025775 (histone H2AX)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100994157 (histone H2AX)
Canis lupus familiaris (dog) : LOC489372 (histone H2AX)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101966907 (histone H2AX)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0848,665,652 - 48,666,981 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0847,284,623 - 47,285,952 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4847,312,609 - 47,313,938 (+)NCBIRGSC3.4rn4RGSC3.4
Celera844,258,161 - 44,259,490 (+)NCBI
Cytogenetic Map8q22NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on H2afx
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RGD Object Information
RGD ID: 1566119
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2017-06-13
Status: ACTIVE