Ddx60 (DEXD/H-box helicase 60) - Rat Genome Database

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Gene: Ddx60 (DEXD/H-box helicase 60) Rattus norvegicus
Analyze
Symbol: Ddx60
Name: DEXD/H-box helicase 60
RGD ID: 1560014
Description: Predicted to enable double-stranded DNA binding activity; double-stranded RNA binding activity; and single-stranded RNA binding activity. Predicted to be involved in positive regulation of MDA-5 signaling pathway; positive regulation of RIG-I signaling pathway; and response to virus. Predicted to act upstream of or within defense response to virus. Predicted to be located in cytosol and intermediate filament cytoskeleton. Orthologous to several human genes including DDX60 (DExD/H-box helicase 60); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07025140.1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 60; hypothetical LOC306407; LOC100911190; LOC306407; LOC306409; mCG11385-like; probable ATP-dependent RNA helicase DDX60; probable ATP-dependent RNA helicase DDX60-like; RGD1560014; similar to hypothetical protein FLJ20035
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81633,087,940 - 33,208,843 (-)NCBIGRCr8
mRatBN7.21628,077,000 - 28,197,903 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01629,816,144 - 29,936,220 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1629,834,086 - 29,936,307 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01629,666,917 - 29,799,963 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41630,934,840 - 31,080,644 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1628,069,864 - 28,080,236 (-)NCBICelera
Cytogenetic Map16p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-alpha-phellandrene  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diethyl maleate  (EXP)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
hydroquinone  (ISO)
Licochalcone B  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
methylmercury chloride  (ISO)
nickel atom  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sotorasib  (ISO)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trametinib  (ISO)
trichostatin A  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21791617  


Genomics

Comparative Map Data
Ddx60
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81633,087,940 - 33,208,843 (-)NCBIGRCr8
mRatBN7.21628,077,000 - 28,197,903 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01629,816,144 - 29,936,220 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1629,834,086 - 29,936,307 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01629,666,917 - 29,799,963 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41630,934,840 - 31,080,644 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1628,069,864 - 28,080,236 (-)NCBICelera
Cytogenetic Map16p12NCBI
DDX60
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384168,216,294 - 168,325,979 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4168,216,291 - 168,318,883 (-)EnsemblGRCh38hg38GRCh38
GRCh374169,137,445 - 169,239,903 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364169,374,020 - 169,476,478 (-)NCBINCBI36Build 36hg18NCBI36
Celera4166,467,307 - 166,569,805 (-)NCBICelera
Cytogenetic Map4q32.3NCBI
HuRef4164,890,816 - 164,992,748 (-)NCBIHuRef
CHM1_14169,114,069 - 169,216,585 (-)NCBICHM1_1
T2T-CHM13v2.04171,575,326 - 171,684,983 (-)NCBIT2T-CHM13v2.0
Ddx60
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39862,381,155 - 62,491,278 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl862,381,121 - 62,491,278 (+)EnsemblGRCm39 Ensembl
GRCm38861,928,073 - 62,037,704 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl861,928,087 - 62,038,244 (+)EnsemblGRCm38mm10GRCm38
MGSCv37864,406,886 - 64,516,492 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36864,820,231 - 64,929,843 (+)NCBIMGSCv36mm8
Celera864,500,606 - 64,610,201 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map831.51NCBI
Ddx60
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540337,679,730 - 37,765,886 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540337,679,939 - 37,765,074 (+)NCBIChiLan1.0ChiLan1.0
DDX60
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23165,926,498 - 166,083,716 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14166,281,937 - 166,439,275 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04160,376,930 - 160,532,561 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14172,501,059 - 172,603,180 (-)NCBIpanpan1.1PanPan1.1panPan2
DDX60
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11563,649,441 - 63,741,357 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1563,649,875 - 63,734,920 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1563,841,588 - 63,933,794 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01564,515,555 - 64,608,252 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11563,738,274 - 63,830,849 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01563,734,311 - 63,826,810 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01564,122,356 - 64,214,849 (-)NCBIUU_Cfam_GSD_1.0
Ddx60
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494320,234,894 - 20,327,258 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936516649,191 - 731,639 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936516649,217 - 735,499 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX60
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1421,083,350 - 21,163,561 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11421,077,491 - 21,163,563 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21422,291,771 - 22,365,670 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DDX60
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17114,474,678 - 114,578,749 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7114,474,680 - 114,578,563 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603794,360,369 - 94,464,299 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Ddx60
1121 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162173597566735975Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162432551369325513Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)162515279370152793Rat

Markers in Region
D16Got31  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21627,910,291 - 27,910,525 (+)MAPPERmRatBN7.2
Rnor_6.01629,906,836 - 29,907,067NCBIRnor6.0
Rnor_5.01629,769,941 - 29,770,172UniSTSRnor5.0
RGSC_v3.41630,909,762 - 30,910,004RGDRGSC3.4
RGSC_v3.41630,909,763 - 30,910,004UniSTSRGSC3.4
RGSC_v3.11630,909,837 - 30,910,079RGD
Celera1628,076,920 - 28,077,151UniSTS
RH 2.0 Map16365.0RGD
AI171488  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21627,906,909 - 27,907,049 (+)MAPPERmRatBN7.2
mRatBN7.21628,147,232 - 28,147,372 (+)MAPPERmRatBN7.2
Rnor_6.01629,903,195 - 29,903,334NCBIRnor6.0
Rnor_5.01629,766,300 - 29,766,439UniSTSRnor5.0
RGSC_v3.41630,904,710 - 30,904,849UniSTSRGSC3.4
Celera1628,073,538 - 28,073,677UniSTS
RH 3.4 Map16332.3UniSTS
RH141454  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21628,077,021 - 28,077,222 (+)MAPPERmRatBN7.2
Rnor_6.01629,804,760 - 29,804,960NCBIRnor6.0
Rnor_5.01629,666,939 - 29,667,139UniSTSRnor5.0
RGSC_v3.41631,081,045 - 31,081,245UniSTSRGSC3.4
RGSC_v3.41630,818,200 - 30,818,400UniSTSRGSC3.4
Celera1627,878,341 - 27,878,541UniSTS
RH 3.4 Map16296.19UniSTS
AI179266  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X58,702,517 - 58,702,657 (+)MAPPERmRatBN7.2
Rnor_6.0X63,058,966 - 63,059,105NCBIRnor6.0
Rnor_6.01629,864,108 - 29,864,246NCBIRnor6.0
Rnor_5.01629,725,091 - 29,725,229UniSTSRnor5.0
Rnor_5.0X63,648,901 - 63,649,040UniSTSRnor5.0
CeleraX59,138,853 - 59,138,992UniSTS
Cytogenetic MapXq31UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000083943   ⟹   ENSRNOP00000072550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084847   ⟹   ENSRNOP00000074273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000088707   ⟹   ENSRNOP00000074057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095521   ⟹   ENSRNOP00000096643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096189   ⟹   ENSRNOP00000095966
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100929   ⟹   ENSRNOP00000087637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101108   ⟹   ENSRNOP00000084996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106980   ⟹   ENSRNOP00000091014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112917   ⟹   ENSRNOP00000097374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119308   ⟹   ENSRNOP00000076782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,076,999 - 28,179,526 (-)Ensembl
RefSeq Acc Id: NM_001419856   ⟹   NP_001406785
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,087,988 - 33,208,839 (-)NCBI
mRatBN7.21628,077,048 - 28,197,900 (-)NCBI
RefSeq Acc Id: XM_039095171   ⟹   XP_038951099
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,097,621 - 33,208,843 (-)NCBI
mRatBN7.21628,086,681 - 28,197,900 (-)NCBI
RefSeq Acc Id: XM_039095173   ⟹   XP_038951101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,134,221 - 33,208,843 (-)NCBI
mRatBN7.21628,123,311 - 28,197,900 (-)NCBI
RefSeq Acc Id: XM_039095174   ⟹   XP_038951102
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,136,655 - 33,208,843 (-)NCBI
mRatBN7.21628,125,715 - 28,197,900 (-)NCBI
RefSeq Acc Id: XM_063274957   ⟹   XP_063131027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,087,940 - 33,208,839 (-)NCBI
RefSeq Acc Id: XM_063274958   ⟹   XP_063131028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,087,940 - 33,208,843 (-)NCBI
RefSeq Acc Id: XM_063274959   ⟹   XP_063131029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,087,940 - 33,208,842 (-)NCBI
RefSeq Acc Id: XM_063274960   ⟹   XP_063131030
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,087,940 - 33,208,705 (-)NCBI
RefSeq Acc Id: XM_063274961   ⟹   XP_063131031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,087,940 - 33,208,843 (-)NCBI
RefSeq Acc Id: XM_063274962   ⟹   XP_063131032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,087,940 - 33,208,843 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038951099   ⟸   XM_039095171
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K744 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951101   ⟸   XM_039095173
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038951102   ⟸   XM_039095174
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000096643   ⟸   ENSRNOT00000095521
RefSeq Acc Id: ENSRNOP00000084996   ⟸   ENSRNOT00000101108
RefSeq Acc Id: ENSRNOP00000072550   ⟸   ENSRNOT00000083943
RefSeq Acc Id: ENSRNOP00000097374   ⟸   ENSRNOT00000112917
RefSeq Acc Id: ENSRNOP00000074273   ⟸   ENSRNOT00000084847
RefSeq Acc Id: ENSRNOP00000091014   ⟸   ENSRNOT00000106980
RefSeq Acc Id: ENSRNOP00000076782   ⟸   ENSRNOT00000119308
RefSeq Acc Id: ENSRNOP00000087637   ⟸   ENSRNOT00000100929
RefSeq Acc Id: ENSRNOP00000074057   ⟸   ENSRNOT00000088707
RefSeq Acc Id: ENSRNOP00000095966   ⟸   ENSRNOT00000096189
RefSeq Acc Id: NP_001406785   ⟸   NM_001419856
RefSeq Acc Id: XP_063131032   ⟸   XM_063274962
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063131031   ⟸   XM_063274961
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063131028   ⟸   XM_063274958
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063131029   ⟸   XM_063274959
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063131027   ⟸   XM_063274957
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063131030   ⟸   XM_063274960
- Peptide Label: isoform X1
Protein Domains
Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K744-F1-model_v2 AlphaFold A0A0G2K744 1-1374 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560014 AgrOrtholog
BioCyc Gene G2FUF-11595 BioCyc
Ensembl Genes ENSRNOG00000059097 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000083943.2 UniProtKB/TrEMBL
  ENSRNOT00000084847.2 UniProtKB/TrEMBL
  ENSRNOT00000088707.2 UniProtKB/TrEMBL
  ENSRNOT00000095521.1 UniProtKB/TrEMBL
  ENSRNOT00000096189.1 UniProtKB/TrEMBL
  ENSRNOT00000100929.1 UniProtKB/TrEMBL
  ENSRNOT00000101108.1 UniProtKB/TrEMBL
  ENSRNOT00000106980.1 UniProtKB/TrEMBL
  ENSRNOT00000112917.1 UniProtKB/TrEMBL
  ENSRNOT00000119308.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Ddx60 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DDX60-RELATED UniProtKB/TrEMBL
  DEAD/H RNA HELICASE, PUTATIVE-RELATED UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PhenoGen Ddx60 PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000059097 RatGTEx
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2K396_RAT UniProtKB/TrEMBL
  A0A0G2K744 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K7M9_RAT UniProtKB/TrEMBL
  A0A8I5XVE3_RAT UniProtKB/TrEMBL
  A0A8I6A0R3_RAT UniProtKB/TrEMBL
  A0A8I6ABA4_RAT UniProtKB/TrEMBL
  A0A8I6AQP8_RAT UniProtKB/TrEMBL
  A0A8I6ASJ5_RAT UniProtKB/TrEMBL
  A0A8I6GFC1_RAT UniProtKB/TrEMBL
  A0A8I6GLV6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Ddx60  DEXD/H-box helicase 60  AABR07025140.1    Data merged from RGD:15012295 737654 PROVISIONAL
2021-03-09 Ddx60  DEXD/H-box helicase 60  LOC100911190  probable ATP-dependent RNA helicase DDX60-like  Data merged from RGD:6494112 737654 PROVISIONAL
2019-11-08 AABR07025140.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2016-01-13 Ddx60  DEXD/H-box helicase 60  Ddx60  DEAD (Asp-Glu-Ala-Asp) box polypeptide 60  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 LOC100911190  probable ATP-dependent RNA helicase DDX60-like  LOC306407  hypothetical LOC306407  Data merged from RGD:1587355 737654 PROVISIONAL
2012-07-05 LOC100911190  probable ATP-dependent RNA helicase DDX60-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-02 Ddx60  DEAD (Asp-Glu-Ala-Asp) box polypeptide 60  LOC100360801  mCG11385-like  Data merged from RGD:2321357 1643240 APPROVED
2010-05-05 LOC100360801  mCG11385-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-28 Ddx60  DEAD (Asp-Glu-Ala-Asp) box polypeptide 60  RGD1560014_predicted  similar to hypothetical protein FLJ20035 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC306407  hypothetical LOC306407      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1560014_predicted  similar to hypothetical protein FLJ20035 (predicted)  LOC306409  similar to hypothetical protein FLJ20035  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC306409  similar to hypothetical protein FLJ20035      Symbol and Name status set to provisional 70820 PROVISIONAL