Gene: Chuk (conserved helix-loop-helix ubiquitous kinase) Rattus norvegicus
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Symbol: Chuk
Name: conserved helix-loop-helix ubiquitous kinase
Description: ENCODES a protein that exhibits IkappaB kinase activity; protein heterodimerization activity; protein homodimerization activity (ortholog); INVOLVED IN response to acetate; response to amino acid; response to drug; PARTICIPATES IN adenosine signaling pathway; FasL mediated signaling pathway; interleukin-1 signaling pathway; ASSOCIATED WITH Colitis; colitis; Muscular Atrophy; FOUND IN cytosol; IkappaB kinase complex; intracellular membrane-bounded organelle; INTERACTS WITH (+)-Tetrandrine; 15-deoxy-Delta(12,14)-prostaglandin J2; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ikbka; Ikka; inhibitor of nuclear factor kappa-B kinase subunit alpha; LOC309361
Orthologs:
Homo sapiens (human) : CHUK (conserved helix-loop-helix ubiquitous kinase)  HGNC  AGR
Mus musculus (house mouse) : Chuk (conserved helix-loop-helix ubiquitous kinase)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Chuk (conserved helix-loop-helix ubiquitous kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : CHUK (conserved helix-loop-helix ubiquitous kinase)
Canis lupus familiaris (dog) : CHUK (conserved helix-loop-helix ubiquitous kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chuk (conserved helix-loop-helix ubiquitous kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01263,848,829 - 263,884,354 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01271,293,821 - 271,329,346 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41249,122,845 - 249,158,369 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11249,381,683 - 249,416,016 (+)NCBI
Celera1238,777,027 - 238,812,551 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Chuk
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306661
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE