Gene: Mthfd1 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase)  Rattus norvegicus
Symbol: Mthfd1
Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
Description: ENCODES a protein that exhibits ATP binding (inferred); formate-tetrahydrofolate ligase activity (inferred); hydrolase activity (inferred); INVOLVED IN nucleotide metabolic process; one-carbon metabolic process; oxidation-reduction process (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; altered folate mediated one-carbon metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH Abruptio Placentae (ortholog); Metabolism, Inborn Errors (ortholog); Neural Tube Defects (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; dibutyl phthalate
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-1-tetrahydrofolate synthase, cytoplasmic; C1-tetrahydrofolate synthase; C1-THF synthase; LOC64300; methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Orthologs: Homo sapiens : MTHFD1 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase)  HGNC
Mus musculus : Mthfd1 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map6q24 NCBI
RGSC Genome Assembly v5.06108,694,405 - 108,761,891+NCBI
RGSC Genome Assembly v3.4698,849,446 - 98,916,936+NCBI
Rat Celera Assembly693,402,792 - 93,470,182+NCBI
Genome Assembly 3.1698,852,901 - 98,920,392+NCBI
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QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

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RGD Object Information
RGD ID: 708531
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2013-05-28
Status: ACTIVE



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