Gene: Tgfb3 (transforming growth factor, beta 3)  Rattus norvegicus

Symbol: Tgfb3
Name: transforming growth factor, beta 3
Description: ENCODES a protein that exhibits protein heterodimerization activity; identical protein binding (ortholog); transforming growth factor beta binding (ortholog); INVOLVED IN activation of MAPK activity; aging; digestive tract development; PARTICIPATES IN glypican signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; cell cycle pathway, mitotic; ASSOCIATED WITH Diabetic Neuropathies; Wounds and Injuries; Arrhythmogenic Right Ventricular Dysplasia, Familial, 1 (ortholog); FOUND IN cell surface; cytoplasm; extracellular space; INTERACTS WITH (R)-noradrenaline; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC105479; TGF-B3; TGF-beta-3; transforming growth factor beta-3
Orthologs: Homo sapiens : TGFB3 (transforming growth factor, beta 3)  HGNC
Mus musculus : Tgfb3 (transforming growth factor, beta 3)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map6q31 NCBI
RGSC Genome Assembly v5.06119,222,052 - 119,243,828-NCBI
RGSC Genome Assembly v3.46110,173,443 - 110,195,215-NCBI
Rat Celera Assembly6103,530,785 - 103,552,563-NCBI
Genome Assembly 3.16110,176,974 - 110,198,746-NCBI
RH 3.46742.1 RGD
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tgfb3
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Ensembl Gene
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RGD Object Information
RGD ID: 3851
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE