| 17alpha-ethynylestradiol | increases expression | ISO | RGD:1320331 | 6480464 | Ethinyl Estradiol results in increased expression of HDAC1 mRNA | CTD | PMID:17942748 |
| 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1320331 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HDAC1 mRNA | CTD | PMID:17942748 |
| 17beta-estradiol | multiple interactions | ISO | RGD:1320330 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Estradiol] promotes the reaction [HDAC1 protein binds to BRCA1 promoter] | CTD | PMID:16489025 |
| 17beta-estradiol | decreases expression | ISO | RGD:1320330 | 6480464 | Estradiol results in decreased expression of HDAC1 mRNA | CTD | PMID:16029874 PMID:23373633 |
| 17beta-estradiol | increases expression | ISO | RGD:1320330 | 6480464 | Estradiol results in increased expression of HDAC1 mRNA | CTD | PMID:22952798 |
| 17beta-estradiol | multiple interactions | ISO | RGD:1320330 | 6480464 | Estradiol inhibits the reaction [sodium arsenite results in increased expression of HDAC1 mRNA]; more ... | CTD | PMID:22952798 |
| 17beta-estradiol | decreases expression | ISO | RGD:1320330 | 6480464 | Estradiol results in decreased expression of HDAC1 mRNA | CTD | PMID:16029874 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1320330 | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [HDAC1 protein binds to BRCA1 promoter]; more ... | CTD | PMID:16489025 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of HDAC1 mRNA | CTD | PMID:22493514 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1320330 | 6480464 | HDAC1 mutant form inhibits the reaction [[IL1B protein co-treated with Tetrachlorodibenzodioxin] results in increased expression of IL6 mRNA]; more ... | CTD | PMID:20511231 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1320331 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HDAC1 mRNA | CTD | PMID:17942748 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1320331 | 6480464 | Tetrachlorodibenzodioxin affects the reaction [HDAC1 protein binds to CYP1A1 promoter] | CTD | PMID:17652329 |
| 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:1320331 | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of HDAC1 mRNA | CTD | PMID:20188158 |
| 4-phenylbutyric acid | multiple interactions | ISO | RGD:1320330 | 6480464 | [4-phenylbutyric acid affects the acetylation of HDAC1 protein] which affects the expression of TUBB3 protein | CTD | PMID:18497984 |
| 5-aza-2'-deoxycytidine | multiple interactions | ISO | RGD:1320330 | 6480464 | decitabine inhibits the reaction [HDAC1 protein binds to CDKN1A promoter] | CTD | PMID:16043219 |
| 5-aza-2'-deoxycytidine | multiple interactions | ISO | RGD:1320330 | 6480464 | decitabine inhibits the reaction [HDAC1 protein binds to BUB1B promoter] | CTD | PMID:17464181 |
| 5-aza-2'-deoxycytidine | multiple interactions | ISO | RGD:1320330 | 6480464 | decitabine inhibits the reaction [HDAC1 protein binds to ABCG2 promoter] | CTD | PMID:16954373 |
| acetylsalicylic acid | increases expression | ISO | RGD:1320330 | 6480464 | Aspirin results in increased expression of HDAC1 mRNA | CTD | PMID:15456535 |
| all-trans-retinoic acid | multiple interactions | ISO | RGD:1320330 | 6480464 | Thiophenes analog promotes the reaction [Tretinoin results in increased expression of HDAC1 mRNA] | CTD | PMID:16140955 |
| all-trans-retinoic acid | increases expression | ISO | RGD:1320330 | 6480464 | Tretinoin results in increased expression of HDAC1 mRNA | CTD | PMID:16140955 |
| ammonium chloride | increases expression | EXP | | 6480464 | Ammonium Chloride results in increased expression of HDAC1 protein | CTD | PMID:16483693 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of HDAC1 mRNA | CTD | PMID:16483693 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:1320331 | 6480464 | Benzo(a)pyrene inhibits the reaction [[DNMT1 protein binds to HDAC1 protein] which binds to CYP1A1 promoter]; more ... | CTD | PMID:17682057 |
| benzo[a]pyrene | decreases expression | ISO | RGD:1320330 | 6480464 | Benzo(a)pyrene results in decreased expression of HDAC1 mRNA | CTD | PMID:16269432 |
| benzo[b]fluoranthene | decreases expression | ISO | RGD:1320330 | 6480464 | benzo(b)fluoranthene results in decreased expression of HDAC1 mRNA | CTD | PMID:16269432 |
| bisphenol A | multiple interactions | EXP | | 6480464 | HDAC1 mutant form inhibits the reaction [bisphenol A results in decreased expression of SLC12A5 mRNA] | CTD | PMID:23440186 |
| C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of HDAC1 mRNA | CTD | PMID:19167457 |
| choline | multiple interactions | ISO | RGD:1320331 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of HDAC1 gene | CTD | PMID:20938992 |
| chromium atom | multiple interactions | ISO | RGD:1320331 | 6480464 | Chromium inhibits the reaction [Benzo(a)pyrene inhibits the reaction [HDAC1 protein binds to CYP1A1 promoter]]; more ... | CTD | PMID:17682057 |
| chromium(6+) | multiple interactions | ISO | RGD:1320330 | 6480464 | chromium hexavalent ion promotes the reaction [HDAC1 protein binds to CDH1 promoter] | CTD | PMID:23518002 |
| ciprofibrate | increases expression | ISO | RGD:1320331 | 6480464 | ciprofibrate results in increased expression of HDAC1 mRNA | CTD | PMID:12771043 |
| cisplatin | multiple interactions | ISO | RGD:1320330 | 6480464 | Cisplatin inhibits the reaction [[HDAC1 protein co-treated with TP63 protein modified form] binds to BBC3 promoter] | CTD | PMID:21527555 |
| cobalt dichloride | multiple interactions | ISO | RGD:1320330 | 6480464 | cobaltous chloride inhibits the reaction [HDAC1 protein binds to HIF1A promoter] | CTD | PMID:19714248 |
| curcumin | multiple interactions | ISO | RGD:1320330 | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 protein]; more ... | CTD | PMID:17927689 |
| curcumin | decreases expression | ISO | RGD:1320330 | 6480464 | Curcumin results in decreased expression of HDAC1 protein | CTD | PMID:18161303 PMID:17927689 |
| curcumin | decreases expression | ISO | RGD:1320330 | 6480464 | Curcumin results in decreased expression of HDAC1 mRNA | CTD | PMID:17927689 |
| curcumin | decreases expression | ISO | RGD:1320330 | 6480464 | Curcumin results in decreased expression of HDAC1 protein | CTD | PMID:17927689 PMID:18161303 |
| curcumin | affects localization | ISO | RGD:1320330 | 6480464 | Curcumin affects the localization of HDAC1 protein | CTD | PMID:17927689 |
| cyclosporin A | decreases expression | ISO | RGD:1320330 | 6480464 | Cyclosporine results in decreased expression of HDAC1 mRNA | CTD | PMID:20106945 |
| dexamethasone | multiple interactions | EXP | | 6480464 | HDAC1 protein inhibits the reaction [Dexamethasone results in increased expression of UCP3 mRNA] | CTD | PMID:17884810 |
| diarsenic trioxide | multiple interactions | ISO | RGD:1320330 | 6480464 | arsenic trioxide promotes the reaction [[TGIF1 protein co-treated with HDAC1 protein] binds to CDKN1A promoter]; more ... | CTD | PMID:18210215 |
| diarsenic trioxide | multiple interactions | ISO | RGD:1320330 | 6480464 | [arsenic trioxide results in increased phosphorylation of JUN protein] which binds to HDAC1 protein; more ... | CTD | PMID:20074581 |
| dibutyl phthalate | decreases expression | ISO | RGD:1320331 | 6480464 | Dibutyl Phthalate results in decreased expression of HDAC1 mRNA | CTD | PMID:21266533 |
| dibutyl phthalate | decreases expression | ISO | RGD:1320331 | 6480464 | Dibutyl Phthalate results in decreased expression of HDAC1 mRNA | CTD | PMID:17361019 PMID:21266533 |
| doxorubicin | multiple interactions | ISO | RGD:1320330 | 6480464 | Doxorubicin promotes the reaction [HDAC1 protein binds to BIRC5 promoter] | CTD | PMID:17124180 |
| folic acid | multiple interactions | ISO | RGD:1320331 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of HDAC1 gene | CTD | PMID:20938992 |
| furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of HDAC1 gene | CTD | PMID:22079235 |
| hydrogen peroxide | decreases expression | ISO | RGD:1320330 | 6480464 | Hydrogen Peroxide results in decreased expression of HDAC1 mRNA | CTD | PMID:12419474 |
| L-methionine | multiple interactions | ISO | RGD:1320331 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of HDAC1 gene | CTD | PMID:20938992 |
| lithium chloride | multiple interactions | ISO | RGD:1320331 | 6480464 | Lithium Chloride inhibits the reaction [HDAC1 protein binds to GCG promoter]; more ... | CTD | PMID:19582394 |
| lovastatin | increases expression | ISO | RGD:1320331 | 6480464 | Lovastatin results in increased expression of HDAC1 mRNA | CTD | PMID:20493250 |
| methylmercury chloride | decreases expression | ISO | RGD:1320331 | 6480464 | methylmercuric chloride results in decreased expression of HDAC1 mRNA | CTD | PMID:20061341 |
| N-ethyl-N-nitrosourea | increases expression | ISO | RGD:1320331 | 6480464 | Ethylnitrosourea results in increased expression of HDAC1 | CTD | PMID:21154115 |
| N-nitrosodiethylamine | multiple interactions | ISO | RGD:1320331 | 6480464 | AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of HDAC1 mRNA] | CTD | PMID:19996281 |
| N-nitrosodiethylamine | increases expression | ISO | RGD:1320331 | 6480464 | Diethylnitrosamine results in increased expression of HDAC1 mRNA | CTD | PMID:12771043 |
| N-nitrosodiethylamine | decreases expression | ISO | RGD:1320331 | 6480464 | Diethylnitrosamine results in decreased expression of HDAC1 mRNA | CTD | PMID:19996281 |
| oleanolic acid | decreases expression | ISO | RGD:1320330 | 6480464 | Oleanolic Acid results in decreased expression of HDAC1 protein | CTD | PMID:20726234 |
| paracetamol | decreases expression | ISO | RGD:1320330 | 6480464 | Acetaminophen results in decreased expression of HDAC1 mRNA | CTD | PMID:21420995 |
| progesterone | decreases expression | ISO | RGD:1320330 | 6480464 | Progesterone results in decreased expression of HDAC1 mRNA | CTD | PMID:18037150 |
| resveratrol | increases expression | ISO | RGD:1320331 | 6480464 | resveratrol results in increased expression of HDAC1 mRNA | CTD | PMID:22610192 |
| resveratrol | multiple interactions | ISO | RGD:1320330 | 6480464 | [resveratrol results in decreased expression of MTA1 protein] inhibits the reaction [MTA1 protein binds to HDAC1 protein]; more ... | CTD | PMID:19810103 |
| tamoxifen | multiple interactions | ISO | RGD:1320330 | 6480464 | Tamoxifen promotes the reaction [HDAC1 protein binds to FOXM1 promoter] | CTD | PMID:20208560 |
| tert-butyl hydroperoxide | decreases expression | ISO | RGD:1320330 | 6480464 | tert-Butylhydroperoxide results in decreased expression of HDAC1 mRNA | CTD | PMID:12419474 |
| theophylline | increases expression | ISO | RGD:1320330 | 6480464 | Theophylline results in increased expression of HDAC1 protein | CTD | PMID:15337792 |
| theophylline | increases expression | ISO | RGD:1320330 | 6480464 | Theophylline results in increased expression of HDAC1 protein | CTD | PMID:15337792 PMID:12070353 |
| theophylline | increases expression | ISO | RGD:1320330 | 6480464 | Theophylline results in increased expression of HDAC1 protein | CTD | PMID:12070353 PMID:15337792 |
| theophylline | increases activity | ISO | RGD:1320330 | 6480464 | Theophylline results in increased activity of HDAC1 protein | CTD | PMID:12070353 |
| trans-resveratrol | increases expression | ISO | RGD:1320331 | 6480464 | resveratrol results in increased expression of HDAC1 mRNA | CTD | PMID:22610192 |
| trans-resveratrol | multiple interactions | ISO | RGD:1320330 | 6480464 | [resveratrol results in decreased expression of MTA1 protein] inhibits the reaction [MTA1 protein binds to HDAC1 protein]; more ... | CTD | PMID:19810103 |
| trichostatin A | decreases activity | ISO | RGD:1320330 | 6480464 | trichostatin A results in decreased activity of HDAC1 protein | CTD | PMID:15930892 more ... |
| trichostatin A | decreases expression | ISO | RGD:1320330 | 6480464 | trichostatin A results in decreased expression of HDAC1 protein | CTD | PMID:23285096 |
| trichostatin A | decreases activity | ISO | RGD:1320330 | 6480464 | trichostatin A results in decreased activity of HDAC1 protein | CTD | PMID:15103026 more ... |
| valproic acid | decreases activity | ISO | RGD:1320330 | 6480464 | Valproic Acid results in decreased activity of HDAC1 protein | CTD | PMID:15103026 |
| zinc atom | multiple interactions | ISO | RGD:1320330 | 6480464 | Zinc binds to and results in increased activity of HDAC1 protein | CTD | PMID:16439135 |
| zinc(0) | multiple interactions | ISO | RGD:1320330 | 6480464 | Zinc binds to and results in increased activity of HDAC1 protein | CTD | PMID:16439135 |